Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes

Arthritis Research and Therapy

Volumn 11, Issue 3, 2009, Pages

  Rasheed, Zafar ^a   Anbazhagan, Arivarasu N ^a   Akhtar, Nahid ^a   Ramamurthy, Sangeetha ^a   Voss, Frank R ^a   Haqqi, Tariq M ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; COLLAGENASE 3; EPIGALLOCATECHIN GALLATE; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ADVANCED GLYCATION END PRODUCTS BOVINE SERUM ALBUMIN; ADVANCED GLYCATION END PRODUCTS-BOVINE SERUM ALBUMIN; BOVINE SERUM ALBUMIN; CATECHIN; DRUG DERIVATIVE; FLAVONOID; PHENOL DERIVATIVE; POLYPHENOLS; PROTEINASE INHIBITOR;

ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; CYTOPLASM; DNA BINDING; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; OSTEOARTHRITIS; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TEA; WESTERN BLOTTING; ZYMOGRAPHY; AGED; BIOSYNTHESIS; CELL CULTURE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; MALE; METABOLISM; MIDDLE AGED;

AGED; CATECHIN; CELLS, CULTURED; CHONDROCYTES; FEMALE; FLAVONOIDS; GENE EXPRESSION REGULATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; MALE; MATRIX METALLOPROTEINASE 13; MIDDLE AGED; PHENOLS; PROTEASE INHIBITORS; SERUM ALBUMIN, BOVINE; TEA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649644339     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2700     Document Type: Article

References (59)

1. Felson DT Lawrence RC Dieppe PA Hirsch R Helmick CG Jordan JM Kington RS Lane NE Nevitt MC Zhang Y Sowers M McAlindon T Spector TD Poole AR Yanovski SZ Ateshian G Sharma L Buckwalter JA Brandt KD Fries JF Osteoarthritis: New insights. I. The disease and its risk factors Ann Intern Med 2000, 133:635-646. 11033593
2. Felson DT Zhang Y An update on the epidemiology of knee and hip osteoarthritis with a view to prevention [review] Arthritis Rheum 1998, 41:1343-1355. 10.1002/ 1529-0131(199808)41:8<1343::AID-ART3>3.0.CO;2-9 9704632
3. Verzijl N Bank RA TeKoppele JM DeGroot J Ageing and osteoarthritis: A different perspective Curr Opin Rheumatol 2003, 15:616-622. 10.1097/ 00002281-200309000-00016 12960490
4. Verzijl N DeGroot J Thorpe SR Bank RA Shaw JN Lyons TJ Bijlsma JW Lafeber FP Baynes JW TeKoppele JM Effect of collagen turnover on the accumulation of advanced glycation end products J Biol Chem 2000, 275:39027-39031. 10.1074/jbc.M006700200 10976109
5. Bank RA Bayliss MT Lafeber FP Maroudas A TeKoppele JM Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage: The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage Biochem J 1998, 330:345-351. 1219146 9461529
6. Verzijl N DeGroot J Oldehinkel E Bank RA Thorpe SR Baynes JW Bayliss MT Bijlsma JW Lafeber FP Tekoppele JM Age-related accumulation of Maillard reaction products in human articular cartilage collagen Biochem J 2000, 350:381-387. 1221264 10947951 10.1042/0264-6021:3500381
7. Verzijl N DeGroot J Ben ZC Brau-Benjamin O Maroudas A Bank RA Mizrahi J Schalkwijk CG Thorpe SR Baynes JW Bijlsma JW Lafeber FP TeKoppele JM Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: A possible mechanism through which age is a risk factor for osteoarthritis Arthritis Rheum 2002, 46:114-123. 10.1002/ 1529-0131(200201)46:1<114::AID-ART10025>3.0.CO;2-P 11822407
8. DeGroot J Bank RA Tchetverikov I Verzijl N TeKoppele JM Molecular markers for osteoarthritis: The road ahead Curr Opin Rheumatol 2002, 14:585-589. 10.1097/00002281-200209000-00019 12192260
9. DeGroot J Verzijl N Bank RA Lafeber FP Bijlsma JW TeKoppele JM Age-related decrease in proteoglycan synthesis of human articular chondrocytes: The role of nonenzymatic glycation Arthritis Rheum 1999, 42:1003-1009. 10.1002/ 1529-0131(199905)42:5<1003::AID-ANR20>3.0.CO;2-K 10323457
10. DeGroot J Verzijl N Wenting-van Wijk MJ Jacobs KM van El B van Roermund PM Bank RA Bijlsma JW TeKoppele JM Lafeber FP Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis Arthritis Rheum 2004, 50:1207-1215. 10.1002/ art.20170 15077303
11. Steenvoorden MM Huizinga TW Verzijl N Bank RA Ronday HK Luning HA Lafeber FP Toes RE DeGroot J Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes Arthritis Rheum 2006, 54:253-263. 10.1002/art.21523 16385542
12. McCance DR Dyer DG Dunn JA Bailie KE Thorpe SR Baynes JW Lyons TJ Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus J Clin Invest 1993, 91:2470-2478. 443307 8514859 10.1172/JCI116482
13. Waine H Nevinny D Rosenthal J Joffe IB Association of osteoarthritis and diabetes mellitus Tufts Folia Med 1961, 7:13-19. 13782559
14. Campbell WL Feldman F Bone and soft tissue abnormalities of the upper extremity in diabetes mellitus Am J Roentgenol Radium Ther Nucl Med 1975, 124:7-16. 1147165
15. Bagge E Bjelle A Eden S Svanborg A Factors associated with radiographic osteoarthritis: Results from the population study 70-year-old people in Göteborg J Rheumatol 1991, 18:1218-1222. 1941827
16. Sunahori K Yamamura M Yamana J Takasugi K Kawashima M Makino H Increased expression of receptor for advanced glycation end products by synovial tissue macrophages in rheumatoid arthritis Arthritis Rheum 2006, 54:97-104. 10.1002/art.21524 16385501
17. Loeser RF Yammani RR Carlson CS Chen H Cole A Im HJ Bursch LS Yan SD Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis Arthritis Rheum 2005, 52:2376-2385. 16052547 10.1002/art.21199 1488730
18. Nah SS Choi IY Yoo B Kim YG Moon H Lee C Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-α in human osteoarthritic chondrocytes FEBS Lett 2007, 581:1928-1932. 10.1016/ j.febslet.2007.03.090 17434489
19. Steenvoorden MM Huizinga TW Verzijl N Bank RA Ronday HK Luning HA Lafeber FP Toes RE DeGroot J Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes Arthritis Rheum 2006, 54:253-263. 10.1002/art.21523 16385542
20. Nah SS Choi IY Lee CK Oh JS Kim YG Moon HB Yoo B Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes Rheumatology (Oxford) 2008, 47:425-431. 10.1093/rheumatology/kem376 18285354
21. Valencia JV Weldon SC Quinn D Kiers GH DeGroot J TeKoppele JM Hughes TE Advanced glycation end product ligands for the receptor for advanced glycation end products: Biochemical characterization and formation kinetics Anal Biochem 2004, 324:68-78. 10.1016/j.ab.2003.09.013 14654047
22. Schmitt A Schmitt J Münch G Gasic-Milencovic J Characterization of advanced glycation end products for biochemical studies: Side chain modifications and fluorescence characteristics Anal Biochem 2005, 338:201-215. 10.1016/j.ab.2004.12.003 15745740
23. Schmitt A Nöller J Schmitt J The binding of advanced glycation end products to cell surfaces can be measured using bead-reconstituted cellular membrane proteins Biochim Biophys Acta 2007, 1768:1389-1399. 10.1016/j.bbamem.2007.03.021 17481574
24. Farboud B Aotaki-Keen A Miyata T Hjelmeland LM Handa JT Development of a polyclonal antibody with broad epitope specificity for advanced glycation end products and localization of these epitopes in Bruch's membrane of the aging eye Mol Vis 1999, 5:11. 10407062
25. Sternlicht MD Werb Z How matrix metalloproteinases regulate cell behavior [review] Annu Rev Cell Dev Biol 2001, 17:463-516. 10.1146/ annurev.cellbio.17.1.463 11687497
26. Rasheed Z Haqqi TM Update on targets of biologic therapies for rheumatoid arthritis Curr Rheum Rev 2008, 4:246-253. 10.2174/ 157339708786263915
27. Khan N Mukhtar H Tea polyphenols for health promotion Life Sci 2007, 81:519-533. 10.1016/j.lfs.2007.06.011 17655876
28. Siddiqui IA Malik A Adhami VM Asim M Hafeez BB Sarfaraz S Mukhtar H Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis Oncogene 2008, 27:2055-2063. 10.1038/sj.onc.1210840 17998943
29. Siddiqui IA Shukla Y Adhami VM Sarfaraz S Asim M Hafeez BB Mukhtar H Suppression of NF κB and its regulated gene products by oral administration of green tea polyphenols in an autochthonous mouse prostate cancer model Pharm Res 2008, 25:2135-2142. 10.1007/ s11095-008-9553-z 18317887
30. Haqqi TM Anthony DD Gupta S Ahmed N Lee MS Kumar GK Mukhtar H Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea Proc Natl Acad Sci USA 1999, 96:4524-4529. 16365 10200295 10.1073/pnas.96.8.4524
31. Singh R Ahmed S Islam N Goldberg VM Haqqi TM Epigallocatechin-3-gallate inhibits interleukin-1β-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: Suppression of nuclear factor kappa B activation by degradation of the inhibitor of nuclear factor kappa B Arthritis Rheum 2002, 46:2079-2086. 10.1002/ art.10443 12209512
32. Ahmed S Wang N Lalonde M Goldberg VM Haqqi TM Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1β-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes J Pharmacol Exp Ther 2004, 308:767-773. 10.1124/jpet.103.059220 14600251
33. Singh R Ahmad S Malemud CJ Goldberg VM Haqqi TM Epigallocatechin-3-gallate selectively inhibits interleukin-1-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes J Orthop Res 2003, 21:102-109. 10.1016/ S0736-0266(02)00089-X 12507586
34. Ahmed S Rahman A Hasnain A Lalonde M Goldberg VM Haqqi TM Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1β-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes Free Radic Biol Med 2002, 33:1097-1105. 10.1016/ S0891-5849(02)01004-3 12374621
35. Mandel S Weinreb O Amit T Youdim MB Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: Implications for neurodegenerative diseases J Neurochem 2004, 88:1555-1569. 15009657
36. Armstrong CG Mow VC Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content J Bone Joint Surg Am 1982, 64:88-94. 7054208
37. Shukla M Gupta K Rasheed Z Khan KA Haqqi TM Bioavailable constituents/ metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1β-induced PGE2 production in human chondrocytes in vitro J Inflamm (Lond) 2008, 5:9. 2438359 18554383 10.1186/1476-9255-5-9
38. Mankin HJ Dorfman H Lippiello L Zarins A Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data J Bone Joint Surg Am 1971, 53:523-537. 5580011
39. Laemmli UK Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 1970, 227:680-685. 10.1038/227680a0 5432063
40. Pfaffl MW A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acid Res 2001, 29:e45. 55695 11328886 10.1093/ nar/29.9.e45
41. Gupta K Shukla M Cowland JB Malemud CJ Haqqi TM Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9 Arthritis Rheum 2007, 56:3326-3335. 17907186 10.1002/art.22879
42. Rasheed Z Akhtar N Anbazhagan AN Ramamurthy S Shukla M Haqqi TM Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells J Inflamm (Lond) 2009, 6:1. 2625340 19133134 10.1186/1476-9255-6-1
43. Hafeez BB Ahmed S Wang N Gupta S Zhang A Haqqi TM Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB Toxicol Appl Pharmacol 2006, 216:11-19. 10.1016/ j.taap.2006.03.013 16797629
44. de Crombrugghe B Lefebvre V Behringer RR Bi W Murakami S Huang W Transcriptional mechanisms of chondrocyte differentiation Matrix Biol 2000, 19:389-394. 10.1016/S0945-053X(00)00094-9 10980415
45. Poole AR Cartilage in health and disease Arthritis and Allied Conditions: A Textbook of Rheumatology Philadelphia: Lippincott Williams & Wilkins Koopman W 14 2001:226-284.
46. Pelletier JP Martel-Pelletier J Abramson SB Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets [review] Arthritis Rheum 2001, 44:1237-1247. 10.1002/ 1529-0131(200106)44:6<1237::AID-ART214>3.0.CO;2-F 11407681
47. Weightman BO Freeman MA Swanson SA Fatigue of articular cartilage Nature 1973, 244:303-304. 10.1038/244303a0 4270399
48. Kempson GE The mechanical properties of articular cartilage The Joints and Synovial Fluid New York: Academic Press Sokoloff L 1980:177-238.
49. Fendrick AM Greenberg BP A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis Osteopath Med Prim Care 2009, 3:1. 2646740 19126235 10.1186/1750-4732-3-1
50. Bellamy N Campbell J Robinson V Gee T Bourne R Wells G Intraarticular corticosteroid for treatment of osteoarthritis of the knee Cochrane Database Syst Rev 2006, 2:CD005328. 16625636
51. Fries JF Bruce B Rates of serious gastrointestinal events from low dose use of acetylsalicylic acid, acetaminophen, and ibuprofen in patients with osteoarthritis and rheumatoid arthritis J Rheumatol 2003, 30:2226-2233. 14528521
52. Adcocks C Collin P Buttle DJ Catechins from green tea (Camellia sinensis) inhibit bovine and human cartilage proteoglycan and type-II collagen degradation in vitro J Nutr 2002, 132:341-346. 11880552
53. Vankemmelbeke MN Jones GC Fowles C Ilic MZ Handley CJ Day AJ Knight CG Mort JS Buttle DJ Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters Eur J Biochem 2003, 270:2394-2403. 10.1046/ j.1432-1033.2003.03607.x 12755694
54. Thalhamer T McGrath MA Harnett MM MAPKs and their relevance to arthritis and inflammation Rheumatology 2008, 47:409-414. 10.1093/rheumatology/ kem297 18187523
55. Hofmann MA Drury S Fu C Qu W Taguchi A Lu Y Avila C Kambham N Bierhaus A Nawroth P Neurath MF Slattery T Beach D McClary J Nagashima M Morser J Stern D Schmidt AM RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides Cell 1999, 97:889-901. 10.1016/S0092-8674(00)80801-6 10399917
56. Finco TS Beg AA Baldwin AS Jr Inducible phosphorylation of IκBα is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors Proc Natl Acad Sci USA 1994, 91:11884-11888. 45340 7991551 10.1073/pnas.91.25.11884
57. Zandi E Rothwarf DM Delhase M Hayakawa M Karin M The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation Cell 1997, 91:243-252. 10.1016/S0092-8674(00)80406-7 9346241
58. DiDonato JA Hayakawa M Rothwarf DM Zandi E Karin M A cytokine-responsive IκB kinase that activates the transcription factor NF-κB Nature 1997, 388:548-554. 10.1038/41493 9252186
59. Azzolina A Bongiovanni A Lampiasi N Substance P induces TNF-α and IL-6 production through NF κB in peritoneal mast cells Biochim Biophys Acta 2003, 1643:75-83. 10.1016/j.bbamcr.2003.09.003 14654230