Efficacy of combination of meloxicam and pregabalin for pain in knee osteoarthritis

Yonsei Medical Journal

Volumn 54, Issue 5, 2013, Pages 1253-1258

  Ohtori, Seiji ^a   Inoue, Gen ^a   Orita, Sumihisa ^a   Takaso, Masashi ^a   Eguchi, Yawara ^a   Ochiai, Nobuyasu ^a   Kishida, Shunji ^a   Kuniyoshi, Kazuki ^a   Aoki, Yasuchika ^a   Ishikawa, Tetsuhiro ^a   Miyagi, Masayuki ^a   Kamoda, Hiroto ^a   Suzkuki, Miyako ^a   Nakamura, Junichi ^a   Kubota, Gou ^a   Sakuma, Yoshihiro ^a   Oikawa, Yasuhiro ^a   Toyone, Tomoaki ^a   Inage, Kazuhide ^a   Sainoh, Takeshi ^a   Yamauchi, Kazuyo ^a   Takahashi, Kazuhisa ^a   more..

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Inflammatory; Knee; Nerve; Neuropathic; Osteoarthritis; Pain; Pregabalin

Indexed keywords

MELOXICAM; PREGABALIN;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANALGESIA; ARTICLE; BEDTIME DOSAGE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; VISUAL ANALOG SCALE; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX; X RAY ANALYSIS;

INFLAMMATORY; KNEE; NERVE; NEUROPATHIC; OSTEOARTHRITIS; PAIN; PREGABALIN;

AGED; AGED, 80 AND OVER; DRUG THERAPY, COMBINATION; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; THIAZINES; THIAZOLES;

EID: 84881011661     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2013.54.5.1253     Document Type: Article

References (24)

1. Paxton EW, Furnes O, Namba RS, Inacio MC, Fenstad AM, Havelin LI. Comparison of the Norwegian knee arthroplasty register and a United States arthroplasty registry. J Bone Joint Surg Am 2011;93 Suppl 3:20-30.
2. Daousi C, MacFarlane IA, Woodward A, Nurmikko TJ, Bundred PE, Benbow SJ. Chronic painful peripheral neuropathy in an urban community: a controlled comparison of people with and without diabetes. Diabet Med 2004;21:976-82.
3. Siddall PJ, McClelland JM, Rutkowski SB, Cousins MJ. A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury. Pain 2003;103:249-57.
4. van der Kraan PM, Vitters EL, van de Putte LB, van den Berg WB. Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints. Am J Pathol 1989; 135:1001-14.
5. Ochiai N, Ohtori S, Sasho T, Nakagawa K, Takahashi K, Takahashi N, et al. Extracorporeal shock wave therapy improves motor dysfunction and pain originating from knee osteoarthritis in rats. Osteoarthritis Cartilage 2007;15:1093-6.
6. Ivanavicius SP, Ball AD, Heapy CG, Westwood FR, Murray F, Read SJ. Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. Pain 2007;128:272-82.
7. Fernihough J, Gentry C, Malcangio M, Fox A, Rediske J, Pellas T, et al. Pain related behaviour in two models of osteoarthritis in the rat knee. Pain 2004;112:83-93.
8. Pomonis JD, Boulet JM, Gottshall SL, Phillips S, Sellers R, Bunton T, et al. Development and pharmacological characterization of a rat model of osteoarthritis pain. Pain 2005;114:339-46.
9. Dworkin RH, O'Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 2007;132:237-51.
10. Freynhagen R, Baron R, Gockel U, Tölle TR. PainDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 2006;22:1911-20.
11. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833-40.
12. Kellgren JH, Lawrence JS. Radiological assessment of osteoarthrosis. Ann Rheum Dis 1957;16:494-501.
13. Pocock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 1975;31:103-15.
14. Hochman JR, French MR, Bermingham SL, Hawker GA. The nerve of osteoarthritis pain. Arthritis Care Res (Hoboken) 2010; 62:1019-23.
15. Grönblad M, Korkala O, Liesi P, Karaharju E. Innervation of synovial membrane and meniscus. Acta Orthop Scand 1985;56:484-6.
16. Fortier LA, Nixon AJ. Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations. J Rheumatol 1997;24:524-30.
17. Saito T, Koshino T. Distribution of neuropeptides in synovium of the knee with osteoarthritis. Clin Orthop Relat Res 2000:172-82.
18. Suri S, Gill SE, Massena de Camin S, Wilson D, McWilliams DF, Walsh DA. Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis. Ann Rheum Dis 2007;66: 1423-8.
19. Ogino S, Sasho T, Nakagawa K, Suzuki M, Yamaguchi S, Higashi M, et al. Detection of pain-related molecules in the subchondral bone of osteoarthritic knees. Clin Rheumatol 2009;28:1395-402.
20. Creamer P, Hunt M, Dieppe P. Pain mechanisms in osteoarthritis of the knee: effect of intraarticular anesthetic. J Rheumatol 1996; 23:1031-6.
21. Ethgen O, Bruyère O, Richy F, Dardennes C, Reginster JY. Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature. J Bone Joint Surg Am 2004;86-A:963-74.
22. Kosek E, Ordeberg G. Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief. Pain 2000;88:69-78.
23. Orita S, Ishikawa T, Miyagi M, Ochiai N, Inoue G, Eguchi Y, et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. BMC Musculoskelet Disord 2011;12:134.
24. Rahman W, Bauer CS, Bannister K, Vonsy JL, Dolphin AC, Dickenson AH. Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. Mol Pain 2009;5:45.