Stimulating effect of diacerein on TGF-β1 and β2 expression in articular chondrocytes cultured with and without interleukin-1

Osteoarthritis and Cartilage

Volumn 7, Issue 3, 1999, Pages 255-264

  Felisaz, Nathalie ^a   Boumediene, Karim ^a   Ghayor, Chafik ^a   Herrouin, Jean Francois ^a   Bogdanowicz, Patrick ^a   Galera, Philippe ^a   Pujol, Jean Pierre ^a  

^a UNIVERSITÉ DE CAEN   (France)

Author keywords

Articular chondrocytes; Diacerein; Interleukin 1; TGF receptors; TGF s

Indexed keywords

COMPLEMENTARY DNA; DIACETYLRHEIN; INTERLEUKIN 1BETA; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATTLE; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0033136710     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.1998.0199     Document Type: Article

References (43)

1. 1. Pelletier J-P, Martel-Pelletier J, Howell DS. Etiopathogenesis of Osteoarthritis. In: McCarty DJ, Koopman WJ, Eds. Arthritis and Allied Conditions: A Textbook of Rheumatology. Philadelphia: Lea and Febiger 1996.
2. 2. Pujol J-P, Loyau G. Interleukin-1 and osteoarthritis. Life Sci 1987;41:1187-98.
3. 3. Pelletier J-P, Martel-Pelletier J. Evidence for the involvement of interleukin-1 in human osteoarthritic cartilage degradation: protective effect of NSAID. J Rheumatol 1989;16:19-27.
4. 4. Mankin HJ. Reaction of articular cartilage to injury and osteoarthritis. N Engl J Med 1974;291:1310-35.
5. 5. Vignon E, Arlot M, Hartmann D, Moyen B, Ville G. Hypertrophic repair of articular cartilage in experimental osteoarthritis. Ann Rheum Dis 1983; 42:82-8.
6. 6. Brandt K. Transection of the anterior cruciate ligament in the dog. A model of osteoarthritis. Semin Arthritis Rheum 1991;21:22-32.
7. 7. Malemud CJ. The role of growth factors in cartilage metabolism. Rheum Dis Clin North Amer 1993; 19:569-80.
8. 8. Pujol J-P, Galéra P, Pronost S, Boumediene K, Vivien D, Macro M et al. Transforming growth factor-β (TGF-β) and articular chondrocytes. Ann Endocrinol 1994;55:109-20.
9. 9. Seyedin SM, Thompson AY, Bentz H, Rosen DM, McPherson JM, Conte A, Sigel NR, Gallupi GR, Piez KA. Cartilage-inducing factor-A. Apparent identity to transforming growth factor-β. J Biol Chem 1986;261:5693-5.
10. 10. Ellingsworth LR, Brennan JE, Fok K, Rosen DM, Bentz H, Piez KA, Seyedin SM. Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor-β. J Biol Chem 1986;261:12,362-7.
11. 11. Frazer A, Seid JM, Hart KA, Bentley H, Bunning RAD, Russell RGG. Detection of mRNA for the transforming growth factor β family in human chondrocytes by the polymerase chain reaction. Biochem Biophys Res Commun 1991;180:602-8.
12. 12. Rédini F, Galéra P, Mauviel A, Loyau G, Pujol J-P. Transforming growth factor β stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit chondrocytes. FEBS Lett 1988;234:172-6.
13. 13. Rédini F, Daireaux M, Mauviel A, Galéra P, Loyau G, Pujol J-P. Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-β (TGF-β). Biochim Biophys Acta 1991;1093:196-206.
14. 14. Morales TI. Transforming growth factor-betasign1 stimulates synthesis of proteoglycan aggregates in calf articular cartilage organ cultures. Arch Biochem Biophys 1991;286:99-106.
15. 15. Van Beuningen HM, van der Kraan PM, Arntz OJ, van den Berg WB. Protection from interleukin-1 induced destruction of articular cartilage by transforming growth factor-β: Studies in anatomically intact cartilage in vitro and in vivo. Ann Rheum Dis 1993;52:185-91.
16. 16. Van Beuningen HM, van der Kraan PM, Arntz OJ, van den Berg WB. In vivo protection against interleukin-1-induced articular cartilage damage by transforming growth factor-β1. Age related differences. Ann Rheum Dis 1994;53:593-600.
17. 17. Pomarelli P, Berti M, Gatti MT, Mosconi P. A non steroidal anti-inflammatory drug that stimulates prostaglandins release. II Farmaco, Ed Sc 1980; 35:836-42.
18. 18. Franchi-Michelli S, Lavacchi L, Friedmann CA, Zilletti L. The influence of rhein on the biosynthesis of prostaglandin-like substances in vitro. J Pharm Pharmacol 1983;35:262-4.
19. 19. Brandt KD, Smith G, Kang SY, Myers S, O'Connor B, Albrecht M. Effects of diacerein in an accelerated canine model of osteoarthritis. Osteoarthritis Cartilage 1997;5:438-49.
20. 20. Moore AR, Greenslade KJ, Alam CA, Willoughby DA. Effects of diacerein on granuloma induced cartilage breakdown in the mouse. Osteoarthritis Cartilage 1998;6:19-23.
21. 21. Mazières B, Berdah L, Thiechart M, Viguier G. Etude de la diacerhéine sur un modèle post contusif d'arthrose expérimentale chez le lapin. Rev Rhum Ed Fr 1993;60:S77-S81.
22. 22. Marcolongo R, Fioravanti A, Adami S, Tozzi, Mian M, Zampieri A. Efficacy and tolerability of diacerein in the treatment of osteoarthrosis. Curr Ther Res 1988;43:878-87.
23. 23. Nguyen M, Dougados M, Berdah L, Amor B. Diacerein in the treatment of osteoarthritis of the hip. Arthritis Rheum 1994;37:529-36.
24. 24. Dougados M, Nguyen M, Berdah L, Lequesne M, Mazieres B, Vignon E. Methodes d'évaluation de l'arthrose: à propos de l'étude ECHODIAH. Rev Prat 1996;46:S53-S56.
25. 25. Boittin M, Redini F, Loyau G, Pujol JP. Effect of diacetylrhein on matrix synthesis and collagenase release in cultured rabbit articular chondrocytes. Rev Rhum 1993;60:68S-76S.
26. 26. Pujol JP. Collagenolytic enzymes and interleukin-1: their role in inflammation and cartilage degradation; the antagonistic effects of diacerein on IL-1 action on cartilage matrix components. Osteoarthritis Cart 1993;1:82.
27. 27. Mian M, Brunelleschi S, Tarli S, Rubino A, Benetti D, Fantozzi R. Rhein: an anthraquinone that modulates superoxide anion production from human neutrophils. J Pharm Pharmacol 1987; 39:845-7.
28. 28. Mian M, Benetti D, Rosini S, Fantozzi R. Effects of diacerein on the quantity and phagocytic activity of thioglycollate-elicited mouse peritoneal macrophages. Pharmacology 1989;39:362-6.
29. 29. Benya PD, Padilla SR, Nimmi ME. The progeny of articular chondrocytes synthesize collagen types I and III trimer, but not type II. Verification by cyanogen bromide peptide analysis. Biochemistry 1977;16:865-72.
30. 30. Lupparello C, Ginty AF, Gallagher JA, Pucci-Minifra I, Minafra S. Transforming growth factorβ1, β2 and β3, urokinase and parathyroid hormone-related peptide expression in 8701-Bc breast cancer cell and clones. Differentiation 1993;55: 73-80.
31. 31. Franzen P, ten Dijke P, Iokijo H, Yamashita H, Schulz P, Heldin CH, Miyazono K. Cloning of TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor. Cell 1992;75:681-92.
32. 32. Lin HY, Wang XF, Ng-Eaton E, Weinberg RA, Lodish HF. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/ threonine kinase. Cell 1992;68:775-85.
33. 33. Siebert D. Quantitative RT-PCR. In: Reischl U, Ed. Methods in Molecular Medicine. Molecular Diagnosis of Infectious Diseases. Totowa, NJ: Humana Press Inc. 1998;13:55-79.
34. 34. Jennings JC, Mohan S, Linkhart TA, Widstrom R. Comparison of the biological actions of TGF-β1 and TGF-β2: differential activity in endothelial cells. J Cell Physiol 1988;137:167-72.
35. 35. Sambrook J, Fritsh EF, Maniatis T. In Molecular Cloning: A Laboratory Manual (second edition). Cold Spring Harbor 1989.
36. 36. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
37. 37. Kim SJ, Glick A, Sporn MB, Roberts AB. Characterization of the promoter region of the human transforming growth factor-beta 1 gene. J Biol Chem 1989;264:402-8.
38. 38. Debord P, Louchahi K, Tod M, Molinier P, Berdah L, Perret G, Petitjean O. Influence of renal function on the pharmacokinetics of diacerein after a single oral dose. Fundam Clin Pharmacol 1993; 7:435-41.
39. 39. Boumédiene K, Conrozier T, Mathieu P, Richard M, Marcelli C, Vignon E, Pujol JP. Decrease of cartilage transforming growth factor-β receptor II expression in the rabbit experimental osteoarthritis - Potential role in cartilage breakdown. Osteoarthritis Cart 1998;6:146-9.
40. 40. Serra R, Johnson M, Filvaroff EH, Laborde J, Sheehan DM, Derynck R, Moses HL. Expression of a truncated, kinase-defective TGF-β type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J Cell Biol 1997;139:541-52.
41. 41. Kim SJ, Angel P, Lafyatis R, Hattori K, Kim KY, Sporn MB, Karim M, Roberts AB. Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex. Mol Cell Biol 1990;10:1492-7.
42. 42. Jakowlew SB, Dillard PJ, Winokur TS, Flanders KC, Sporn MB, Roberts AB. Expression of transforming growth factor-βs 1-4 in chicken embryo chondrocytes and myocytes. Dev Biol 1991; 143:135-48.
43. 43. Roberts AB, Sporn MB. Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues. Mol Repr Dev 1992;32:91-8.