ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

PLoS Biology

Volumn 13, Issue 12, 2015, Pages

  Muthusamy, Baby Periyanayaki ^a   Budi, Erine H ^a   Katsuno, Yoko ^a,f   Lee, Matthew K ^b   Smith, Susan M ^b   Mirza, Amer M ^c   Akhurst, Rosemary J ^a,d,e   Derynck, Rik ^a,d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c XOMA Corporation   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SHC SIGNALING ADAPTOR PROTEIN; SHC TRANSFORMING PROTEIN 1; SHC1 PROTEIN, HUMAN; SHC1 PROTEIN, MOUSE; SMAD2 PROTEIN; SMAD2 PROTEIN, HUMAN; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN; SMAD3 PROTEIN, HUMAN; SMAD3 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL MEMBRANE; CYTOLOGY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KERATINOCYTE; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; RNA INTERFERENCE; UDDER;

ANIMALS; CELL LINE; CELL MEMBRANE; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; KERATINOCYTES; MAMMARY GLANDS, ANIMAL; MICE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RNA INTERFERENCE; SHC SIGNALING ADAPTOR PROTEINS; SMAD2 PROTEIN; SMAD3 PROTEIN; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 84953242016     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002325     Document Type: Article

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