Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model

Breast Cancer Research

Volumn 15, Issue 6, 2013, Pages

  Drabsch, Yvette ^a   He, Shuning ^b   Zhang, Long ^a,d   Snaar Jagalska, B E ^b   ten Dijke, Peter ^a,c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UPPSALA UNIVERSITY   (Sweden)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ILOMASTAT; MATRIX METALLOPROTEINASE; SHORT HAIRPIN RNA; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; 1,3 DIOXOLANE DERIVATIVE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; CHROMONE DERIVATIVE; DIPEPTIDE; ENZYME INHIBITOR; MATRIX METALLOPROTEINASE INHIBITOR; MOLECULAR LIBRARY; MORPHOLINE DERIVATIVE; N-(2(R)-2-(HYDROXAMIDOCARBONYLMETHYL)-4-METHYLPENTANOYL)-L-TRYPTOPHAN METHYLAMIDE; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN; SMAD2 PROTEIN, ZEBRAFISH; SMAD4 PROTEIN, ZEBRAFISH; TGF-BETA TYPE I RECEPTOR; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST METASTASIS; CARCINOGENICITY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HEMATOPOIETIC TISSUE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; TUMOR INVASION; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; EMBRYOLOGY; FEMALE; GENETICS; METABOLISM; MOLECULAR LIBRARY; PATHOLOGY; PHARMACOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

ANIMALS; BENZAMIDES; BREAST NEOPLASMS; CHROMONES; DIOXOLES; DIPEPTIDES; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; EMBRYO, NONMAMMALIAN; ENZYME INHIBITORS; FEMALE; HUMANS; MATRIX METALLOPROTEINASE INHIBITORS; MORPHOLINES; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD4 PROTEIN; SMALL MOLECULE LIBRARIES; TRANSFORMING GROWTH FACTOR BETA; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84887040380     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3573     Document Type: Article

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