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Volumn 1, Issue 4, 1998, Pages 611-617

Human Smad3 and Smad4 are sequence-specific transcription activators

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; SMAD3 PROTEIN; SMAD3 PROTEIN, HUMAN; SMAD4 PROTEIN; SMAD4 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032014216     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80061-1     Document Type: Article
Times cited : (918)

References (39)
  • 1
    • 0029829230 scopus 로고    scopus 로고
    • A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
    • Baker, J.C., and Harland, R.M. (1996). A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 10, 1880-1889.
    • (1996) Genes Dev. , vol.10 , pp. 1880-1889
    • Baker, J.C.1    Harland, R.M.2
  • 2
    • 0028359376 scopus 로고
    • Type I receptors specify growth-inhibitory and transcriptional responses to TGF-β and activin
    • Carcamo, J., Weis, F.M., Ventura, F., Wieser, R., Wrana, J.L., Attisano, L., and Massague, J. (1994). Type I receptors specify growth-inhibitory and transcriptional responses to TGF-β and activin. Mol. Cell. Biol. 14, 3810-3821.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3810-3821
    • Carcamo, J.1    Weis, F.M.2    Ventura, F.3    Wieser, R.4    Wrana, J.L.5    Attisano, L.6    Massague, J.7
  • 3
    • 0028894025 scopus 로고
    • Disruption of TGF-β signaling by a mutation that prevents transphosphorylation within the receptor complex
    • Carcamo, J., Zentella, A., and Massague, J. (1995). Disruption of TGF-β signaling by a mutation that prevents transphosphorylation within the receptor complex. Mol. Cell. Biol. 15, 1573-1581.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1573-1581
    • Carcamo, J.1    Zentella, A.2    Massague, J.3
  • 4
    • 0029802485 scopus 로고    scopus 로고
    • A transcriptional partner for MAD proteins in TGF-β signaling
    • Chen, X., Rubock, M.J., and Whitman, M. (1996). A transcriptional partner for MAD proteins in TGF-β signaling. Nature 383, 691-696.
    • (1996) Nature , vol.383 , pp. 691-696
    • Chen, X.1    Rubock, M.J.2    Whitman, M.3
  • 9
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signaling from cell membrane to nucleus through SMAD proteins
    • Heldin, C.H., Miyazono, K., and ten Dijke, P. (1997). TGF-β signaling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 11
    • 0029892494 scopus 로고    scopus 로고
    • MADR1, a MAD-related protein that functions in BMP2 signaling pathways
    • Hoodless, P. (1996). MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85, 489-500.
    • (1996) Cell , vol.85 , pp. 489-500
    • Hoodless, P.1
  • 12
    • 0030787152 scopus 로고    scopus 로고
    • Mechanism and function of signaling by the TGF-β superfamily
    • Hoodless, P.A., and Wrana, J.L. (1998). Mechanism and function of signaling by the TGF-β superfamily. Curr. Top. Microbiol. Immunol. 228, 235-272.
    • (1998) Curr. Top. Microbiol. Immunol. , vol.228 , pp. 235-272
    • Hoodless, P.A.1    Wrana, J.L.2
  • 13
    • 0031057713 scopus 로고    scopus 로고
    • DPC4 gene mutation in colitis associated neoplasia
    • Hoque, A.T., Hahn, S.A., Schutte, M., and Kern, S.E. (1997). DPC4 gene mutation in colitis associated neoplasia. Gut 40, 120-122.
    • (1997) Gut , vol.40 , pp. 120-122
    • Hoque, A.T.1    Hahn, S.A.2    Schutte, M.3    Kern, S.E.4
  • 14
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • Kim, J., Johnson, K., Chen, H.J., Carroll, S., and Laughon, A. (1997). Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.
    • (1997) Nature , vol.388 , pp. 304-308
    • Kim, J.1    Johnson, K.2    Chen, H.J.3    Carroll, S.4    Laughon, A.5
  • 15
    • 0024346502 scopus 로고
    • Whole genome PCR: Application to the identification of sequences bound by gene regulatory proteins
    • Kinzler, K.W., and Vogelstein, B. (1989). Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins. Nucleic Acids Res. 17, 3645-3653.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 3645-3653
    • Kinzler, K.W.1    Vogelstein, B.2
  • 16
    • 0030911104 scopus 로고    scopus 로고
    • The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
    • Kretzschmar, M., Liu, F., Hata, A., Doody, J., and Massague, J. (1997). The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev. 11, 984-995.
    • (1997) Genes Dev. , vol.11 , pp. 984-995
    • Kretzschmar, M.1    Liu, F.2    Hata, A.3    Doody, J.4    Massague, J.5
  • 17
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-β signaling pathways
    • Lagna, G., Hata, A., Hemmati-Brivanlou, A., and Massague, J. (1996). Partnership between DPC4 and SMAD proteins in TGF-β signaling pathways. Nature 383, 832-836.
    • (1996) Nature , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massague, J.4
  • 18
    • 0026767150 scopus 로고
    • Modifications of cell cycle controlling nuclear proteins by TGF-β in the HaCaT keratinocyte cell line
    • Landesman, Y., Pagano, M., Draetta, G., Rotter, V., Fusenig, N.E., and Kimchi, A. (1992). Modifications of cell cycle controlling nuclear proteins by TGF-β in the HaCaT keratinocyte cell line. Oncogene 7, 1661-1665.
    • (1992) Oncogene , vol.7 , pp. 1661-1665
    • Landesman, Y.1    Pagano, M.2    Draetta, G.3    Rotter, V.4    Fusenig, N.E.5    Kimchi, A.6
  • 19
  • 20
    • 0030690337 scopus 로고    scopus 로고
    • Dual role of the Smad4/DPC4 tumor suppressor in TGF-β-inducible transcriptional complexes
    • Liu, F., Pouponnot, C., and Massague, J. (1997a). Dual role of the Smad4/DPC4 tumor suppressor in TGF-β-inducible transcriptional complexes. Genes Dev. 11, 3157-3167.
    • (1997) Genes Dev. , vol.11 , pp. 3157-3167
    • Liu, F.1    Pouponnot, C.2    Massague, J.3
  • 21
    • 0030886204 scopus 로고    scopus 로고
    • TGF-β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
    • Liu, X., Sun, Y., Constantinescu, S.N., Karam, E., Weinberg, R.A., and Lodish, H.F. (1997b). TGF-β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA 94, 10669-10674.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10669-10674
    • Liu, X.1    Sun, Y.2    Constantinescu, S.N.3    Karam, E.4    Weinberg, R.A.5    Lodish, H.F.6
  • 22
    • 0030300115 scopus 로고    scopus 로고
    • MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
    • Macias-Silva, M., Abdollah, S., Hoodless, P.A., Pirone, R., Attisano, L., and Wrana, J.L. (1996). MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215-1224.
    • (1996) Cell , vol.87 , pp. 1215-1224
    • Macias-Silva, M.1    Abdollah, S.2    Hoodless, P.A.3    Pirone, R.4    Attisano, L.5    Wrana, J.L.6
  • 26
    • 0031570511 scopus 로고    scopus 로고
    • Differential effect of Nonidet P40 on DNA binding of transcription factors
    • Nakshatri, H., and Bhat-Nakshatri, P. (1997). Differential effect of Nonidet P40 on DNA binding of transcription factors. Anal. Biochem. 249, 103-104.
    • (1997) Anal. Biochem. , vol.249 , pp. 103-104
    • Nakshatri, H.1    Bhat-Nakshatri, P.2
  • 27
    • 0024365536 scopus 로고
    • Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: Analysis of yeast GCN4 protein
    • Oliphant, A.R., Brandl, C.J., and Struhl, K. (1989). Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein. Mol. Cell. Biol. 9, 2944-2949.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2944-2949
    • Oliphant, A.R.1    Brandl, C.J.2    Struhl, K.3
  • 31
    • 0028940853 scopus 로고
    • Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
    • Sekelsky, J.J., Newfeld, S.J., Raftery, L.A., Chartoff, E.H., and Gelbart, W.M. (1995). Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.
    • (1995) Genetics , vol.139 , pp. 1347-1358
    • Sekelsky, J.J.1    Newfeld, S.J.2    Raftery, L.A.3    Chartoff, E.H.4    Gelbart, W.M.5
  • 32
    • 0030837455 scopus 로고    scopus 로고
    • A structural basis for mutational inactivation of the tumour suppressor Smad4
    • Shi, Y., Hata, A., Lo, R.S., Massague, J., and Pavletich, N.P. (1997). A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87-93.
    • (1997) Nature , vol.388 , pp. 87-93
    • Shi, Y.1    Hata, A.2    Lo, R.S.3    Massague, J.4    Pavletich, N.P.5
  • 33
    • 15844390729 scopus 로고    scopus 로고
    • Evaluation of chromosome 18q in colorectal cancers
    • Thiagalingam, S. (1996). Evaluation of chromosome 18q in colorectal cancers. Nat. Genet. 13, 343-346.
    • (1996) Nat. Genet. , vol.13 , pp. 343-346
    • Thiagalingam, S.1
  • 34
    • 0029131403 scopus 로고
    • Demonstration that mutation of the type II TGF-β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
    • Wang, J., Sun, L., Myeroff, L., Wang, X., Gentry, L.E., Yang, J., Liang, J., Zborowska, E., Markowitz, S., Willson, J.K., et al. (1995). Demonstration that mutation of the type II TGF-β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J. Biol. Chem. 270, 22044-22049.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22044-22049
    • Wang, J.1    Sun, L.2    Myeroff, L.3    Wang, X.4    Gentry, L.E.5    Yang, J.6    Liang, J.7    Zborowska, E.8    Markowitz, S.9    Willson, J.K.10
  • 36
    • 0030974042 scopus 로고    scopus 로고
    • Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
    • Wu, R.Y., Zhang, Y., Feng, X.H., and Derynck, R. (1997). Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4. Mol. Cell. Biol. 17, 2521-2528.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2521-2528
    • Wu, R.Y.1    Zhang, Y.2    Feng, X.H.3    Derynck, R.4
  • 38
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-β response
    • Zhang, Y., Feng, X., Wu, R., and Derynck, R. (1996). Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383, 168-172.
    • (1996) Nature , vol.383 , pp. 168-172
    • Zhang, Y.1    Feng, X.2    Wu, R.3    Derynck, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.