-
1
-
-
77950346282
-
Immunity, inflammation, and cancer
-
20303878 2866629
-
Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140(6):883-899
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
2
-
-
84857141296
-
Cancer-related inflammation: Common themes and therapeutic opportunities
-
22210179
-
Balkwill FR, Mantovani A (2012) Cancer-related inflammation: common themes and therapeutic opportunities. Semin Cancer Biol 22(1):33-40
-
(2012)
Semin Cancer Biol
, vol.22
, Issue.1
, pp. 33-40
-
-
Balkwill, F.R.1
Mantovani, A.2
-
3
-
-
84872445265
-
Neutralizing tumor-promoting chronic inflammation: A magic bullet?
-
23329041 3591506
-
Coussens LM, Zitvogel L, Palucka AK (2013) Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 339(6117):286-291
-
(2013)
Science
, vol.339
, Issue.6117
, pp. 286-291
-
-
Coussens, L.M.1
Zitvogel, L.2
Palucka, A.K.3
-
4
-
-
59449085264
-
Targeting inflammatory pathways for prevention and therapy of cancer: Short-term friend, long-term foe
-
19147746
-
Aggarwal BB, Vijayalekshmi RV, Sung B (2009) Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe. Clin Cancer Res 15(2):425-430
-
(2009)
Clin Cancer Res
, vol.15
, Issue.2
, pp. 425-430
-
-
Aggarwal, B.B.1
Vijayalekshmi, R.V.2
Sung, B.3
-
5
-
-
17644394616
-
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
-
15766659
-
Balkwill F, Charles KA, Mantovani A (2005) Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7(3):211-217
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 211-217
-
-
Balkwill, F.1
Charles, K.A.2
Mantovani, A.3
-
6
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
16724054
-
Karin M (2006) Nuclear factor-kappaB in cancer development and progression. Nature 441(7092):431-436
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
7
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
19701202 3034219
-
Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL (2009) A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 15(9):1016-1022
-
(2009)
Nat Med
, vol.15
, Issue.9
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
Rabizadeh, S.4
Wu, X.5
Yen, H.R.6
Huso, D.L.7
Brancati, F.L.8
Wick, E.9
McAllister, F.10
Housseau, F.11
Pardoll, D.M.12
Sears, C.L.13
-
8
-
-
84888633713
-
Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms
-
24154716
-
Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA (2013) Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer 13(11):759-771
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.11
, pp. 759-771
-
-
Elinav, E.1
Nowarski, R.2
Thaiss, C.A.3
Hu, B.4
Jin, C.5
Flavell, R.A.6
-
9
-
-
84905381214
-
The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis
-
25082194
-
McAllister SS, Weinberg RA (2014) The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nat Cell Biol 16(8):717-727
-
(2014)
Nat Cell Biol
, vol.16
, Issue.8
, pp. 717-727
-
-
McAllister, S.S.1
Weinberg, R.A.2
-
10
-
-
84928749945
-
New horizons in tumor microenvironment biology: Challenges and opportunities
-
25857315 4350882
-
Chen F, Zhuang X, Lin L, Yu P, Wang Y, Shi Y, Hu G, Sun Y (2015) New horizons in tumor microenvironment biology: challenges and opportunities. BMC Med 13:45
-
(2015)
BMC Med
, vol.13
, pp. 45
-
-
Chen, F.1
Zhuang, X.2
Lin, L.3
Yu, P.4
Wang, Y.5
Shi, Y.6
Hu, G.7
Sun, Y.8
-
11
-
-
84901767734
-
Chronic inflammation and cytokines in the tumor microenvironment
-
24901008 4036716
-
Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA (2014) Chronic inflammation and cytokines in the tumor microenvironment. J Immunol Res 2014:149185
-
(2014)
J Immunol Res
, vol.2014
, pp. 149185
-
-
Landskron, G.1
De La Fuente, M.2
Thuwajit, P.3
Thuwajit, C.4
Hermoso, M.A.5
-
12
-
-
34249337761
-
Perceptions of epigenetics
-
17522671
-
Bird A (2007) Perceptions of epigenetics. Nature 447(7143):396-398
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 396-398
-
-
Bird, A.1
-
13
-
-
67349240804
-
Metabolic defects provide a spark for the epigenetic switch in cancer
-
19362589 2728018
-
Hitchler MJ, Domann FE (2009) Metabolic defects provide a spark for the epigenetic switch in cancer. Free Radic Biol Med 47(2):115-127
-
(2009)
Free Radic Biol Med
, vol.47
, Issue.2
, pp. 115-127
-
-
Hitchler, M.J.1
Domann, F.E.2
-
14
-
-
0017145368
-
Autoregulation and function of a repressor in bacteriophage lambda
-
959843
-
Ptashne M, Backman K, Humayun MZ, Jeffrey A, Maurer R, Meyer B, Sauer RT (1976) Autoregulation and function of a repressor in bacteriophage lambda. Science 194(4261):156-161
-
(1976)
Science
, vol.194
, Issue.4261
, pp. 156-161
-
-
Ptashne, M.1
Backman, K.2
Humayun, M.Z.3
Jeffrey, A.4
Maurer, R.5
Meyer, B.6
Sauer, R.T.7
-
15
-
-
84938310296
-
A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element
-
25108384 4270207
-
Herzog VA, Lempradl A, Trupke J, Okulski H, Altmutter C, Ruge F, Boidol B, Kubicek S, Schmauss G, Aumayr K, Ruf M, Pospisilik A, Dimond A, Senergin HB, Vargas ML, Simon JA, Ringrose L (2014) A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet 46(9):973-981
-
(2014)
Nat Genet
, vol.46
, Issue.9
, pp. 973-981
-
-
Herzog, V.A.1
Lempradl, A.2
Trupke, J.3
Okulski, H.4
Altmutter, C.5
Ruge, F.6
Boidol, B.7
Kubicek, S.8
Schmauss, G.9
Aumayr, K.10
Ruf, M.11
Pospisilik, A.12
Dimond, A.13
Senergin, H.B.14
Vargas, M.L.15
Simon, J.A.16
Ringrose, L.17
-
16
-
-
84868514154
-
Vernalization: A cold-induced epigenetic switch
-
22935652, PT 16
-
Song J, Angel A, Howard M, Dean C (2012) Vernalization: a cold-induced epigenetic switch. J Cell Sci 125(Pt 16):3723-3731
-
(2012)
J Cell Sci
, vol.125
, pp. 3723-3731
-
-
Song, J.1
Angel, A.2
Howard, M.3
Dean, C.4
-
17
-
-
84906777828
-
An epigenetic switch of the brain sex as a basis of gendered behavior in Drosophila
-
25172345
-
Sato K, Yamamoto D (2014) An epigenetic switch of the brain sex as a basis of gendered behavior in Drosophila. Adv Genet 86:45-63
-
(2014)
Adv Genet
, vol.86
, pp. 45-63
-
-
Sato, K.1
Yamamoto, D.2
-
18
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
19878981 2783826
-
Iliopoulos D, Hirsch HA, Struhl K (2009) An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 139(4):693-706
-
(2009)
Cell
, vol.139
, Issue.4
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
19
-
-
84862806829
-
IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis
-
22364742 3319241
-
Rokavec M, Wu W, Luo JL (2012) IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis. Mol Cell 45(6):777-789
-
(2012)
Mol Cell
, vol.45
, Issue.6
, pp. 777-789
-
-
Rokavec, M.1
Wu, W.2
Luo, J.L.3
-
20
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
23827675 4015106
-
Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, D'Alessio AC, Young RA, Weinberg RA (2013) Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154(1):61-74
-
(2013)
Cell
, vol.154
, Issue.1
, pp. 61-74
-
-
Chaffer, C.L.1
Marjanovic, N.D.2
Lee, T.3
Bell, G.4
Kleer, C.G.5
Reinhardt, F.6
D'Alessio, A.C.7
Young, R.A.8
Weinberg, R.A.9
-
21
-
-
84890226018
-
Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma
-
24332177
-
Chiou GY, Chien CS, Wang ML, Chen MT, Yang YP, Yu YL, Chien Y, Chang YC, Shen CC, Chio CC, Lu KH, Ma HI, Chen KH, Liu DM, Miller SA, Chen YW, Huang PI, Shih YH, Hung MC, Chiou SH (2013) Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma. Mol Cell 52(5):693-706
-
(2013)
Mol Cell
, vol.52
, Issue.5
, pp. 693-706
-
-
Chiou, G.Y.1
Chien, C.S.2
Wang, M.L.3
Chen, M.T.4
Yang, Y.P.5
Yu, Y.L.6
Chien, Y.7
Chang, Y.C.8
Shen, C.C.9
Chio, C.C.10
Lu, K.H.11
Ma, H.I.12
Chen, K.H.13
Liu, D.M.14
Miller, S.A.15
Chen, Y.W.16
Huang, P.I.17
Shih, Y.H.18
Hung, M.C.19
Chiou, S.H.20
more..
-
22
-
-
84887456252
-
The epigenetics of epithelial-mesenchymal plasticity in cancer
-
24202396 4190672
-
Tam WL, Weinberg RA (2013) The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat Med 19(11):1438-1449
-
(2013)
Nat Med
, vol.19
, Issue.11
, pp. 1438-1449
-
-
Tam, W.L.1
Weinberg, R.A.2
-
23
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
11782440
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16(1):6-21
-
(2002)
Genes Dev
, vol.16
, Issue.1
, pp. 6-21
-
-
Bird, A.1
-
24
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
12042769
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3(6):415-428
-
(2002)
Nat Rev Genet
, vol.3
, Issue.6
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
25
-
-
80053144962
-
A decade of exploring the cancer epigenome - Biological and translational implications
-
21941284 3307543
-
Baylin SB, Jones PA (2011) A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer 11(10):726-734
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.10
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
26
-
-
84901853867
-
Cancer epigenetics: Tumor heterogeneity, plasticity of stem-like states, and drug resistance
-
24905005 4103691
-
Easwaran H, Tsai HC, Baylin SB (2014) Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. Mol Cell 54(5):716-727
-
(2014)
Mol Cell
, vol.54
, Issue.5
, pp. 716-727
-
-
Easwaran, H.1
Tsai, H.C.2
Baylin, S.B.3
-
27
-
-
0032845039
-
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
-
10471500
-
Wade PA, Gegonne A, Jones PL, Ballestar E, Aubry F, Wolffe AP (1999) Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation. Nat Genet 23(1):62-66
-
(1999)
Nat Genet
, vol.23
, Issue.1
, pp. 62-66
-
-
Wade, P.A.1
Gegonne, A.2
Jones, P.L.3
Ballestar, E.4
Aubry, F.5
Wolffe, A.P.6
-
28
-
-
0034713375
-
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
-
10839546
-
Bell AC, Felsenfeld G (2000) Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405(6785):482-485
-
(2000)
Nature
, vol.405
, Issue.6785
, pp. 482-485
-
-
Bell, A.C.1
Felsenfeld, G.2
-
29
-
-
0034713275
-
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
-
10839547
-
Hark AT, Schoenherr CJ, Katz DJ, Ingram RS, Levorse JM, Tilghman SM (2000) CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 405(6785):486-489
-
(2000)
Nature
, vol.405
, Issue.6785
, pp. 486-489
-
-
Hark, A.T.1
Schoenherr, C.J.2
Katz, D.J.3
Ingram, R.S.4
Levorse, J.M.5
Tilghman, S.M.6
-
30
-
-
0033404952
-
Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production
-
10587350 2195731
-
Hmadcha A, Bedoya FJ, Sobrino F, Pintado E (1999) Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production. J Exp Med 190(11):1595-1604
-
(1999)
J Exp Med
, vol.190
, Issue.11
, pp. 1595-1604
-
-
Hmadcha, A.1
Bedoya, F.J.2
Sobrino, F.3
Pintado, E.4
-
31
-
-
41049086674
-
E-Cadherin promoter hypermethylation induced by interleukin-1beta treatment or H. Pylori infection in human gastric cancer cell lines
-
18249489
-
Qian X, Huang C, Cho CH, Hui WM, Rashid A, Chan AO (2008) E-cadherin promoter hypermethylation induced by interleukin-1beta treatment or H. pylori infection in human gastric cancer cell lines. Cancer Lett 263(1):107-113
-
(2008)
Cancer Lett
, vol.263
, Issue.1
, pp. 107-113
-
-
Qian, X.1
Huang, C.2
Cho, C.H.3
Hui, W.M.4
Rashid, A.5
Chan, A.O.6
-
32
-
-
84867332710
-
Helicobacter pylori induces promoter methylation of E-cadherin via interleukin-1beta activation of nitric oxide production in gastric cancer cells
-
22415887
-
Huang FY, Chan AO, Rashid A, Wong DK, Cho CH, Yuen MF (2012) Helicobacter pylori induces promoter methylation of E-cadherin via interleukin-1beta activation of nitric oxide production in gastric cancer cells. Cancer 118(20):4969-4980
-
(2012)
Cancer
, vol.118
, Issue.20
, pp. 4969-4980
-
-
Huang, F.Y.1
Chan, A.O.2
Rashid, A.3
Wong, D.K.4
Cho, C.H.5
Yuen, M.F.6
-
33
-
-
84922024758
-
TGF-beta induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells
-
25470663 4622747
-
Cardenas H, Vieth E, Lee J, Segar M, Liu Y, Nephew KP, Matei D (2014) TGF-beta induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells. Epigenetics 9(11):1461-1472
-
(2014)
Epigenetics
, vol.9
, Issue.11
, pp. 1461-1472
-
-
Cardenas, H.1
Vieth, E.2
Lee, J.3
Segar, M.4
Liu, Y.5
Nephew, K.P.6
Matei, D.7
-
34
-
-
77951460399
-
Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta
-
20196115 2862140
-
You H, Ding W, Rountree CB (2010) Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta. Hepatology 51(5):1635-1644
-
(2010)
Hepatology
, vol.51
, Issue.5
, pp. 1635-1644
-
-
You, H.1
Ding, W.2
Rountree, C.B.3
-
35
-
-
84875684822
-
Transforming growth factor beta1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts
-
23560091 3613378
-
Pan X, Chen Z, Huang R, Yao Y, Ma G (2013) Transforming growth factor beta1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts. PLoS ONE 8(4):e60335
-
(2013)
PLoS ONE
, vol.8
, Issue.4
, pp. e60335
-
-
Pan, X.1
Chen, Z.2
Huang, R.3
Yao, Y.4
Ma, G.5
-
36
-
-
77951188458
-
Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6
-
20354000
-
Foran E, Garrity-Park MM, Mureau C, Newell J, Smyrk TC, Limburg PJ, Egan LJ (2010) Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. Mol Cancer Res 8(4):471-481
-
(2010)
Mol Cancer Res
, vol.8
, Issue.4
, pp. 471-481
-
-
Foran, E.1
Garrity-Park, M.M.2
Mureau, C.3
Newell, J.4
Smyrk, T.C.5
Limburg, P.J.6
Egan, L.J.7
-
37
-
-
0035955640
-
Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells
-
11551897
-
Hodge DR, Xiao W, Clausen PA, Heidecker G, Szyf M, Farrar WL (2001) Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells. J Biol Chem 276(43):39508-39511
-
(2001)
J Biol Chem
, vol.276
, Issue.43
, pp. 39508-39511
-
-
Hodge, D.R.1
Xiao, W.2
Clausen, P.A.3
Heidecker, G.4
Szyf, M.5
Farrar, W.L.6
-
38
-
-
84911004173
-
IL-6 enriched lung cancer stem-like cell population by inhibition of cell cycle regulators via DNMT1 upregulation
-
24947242
-
Liu CC, Lin JH, Hsu TW, Su K, Li AF, Hsu HS, Hung SC (2015) IL-6 enriched lung cancer stem-like cell population by inhibition of cell cycle regulators via DNMT1 upregulation. Int J Cancer 136(3):547-559
-
(2015)
Int J Cancer
, vol.136
, Issue.3
, pp. 547-559
-
-
Liu, C.C.1
Lin, J.H.2
Hsu, T.W.3
Su, K.4
Li, A.F.5
Hsu, H.S.6
Hung, S.C.7
-
39
-
-
84861215508
-
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation
-
22547799 3356652
-
Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, Hoon DS, Forman SJ, Jove R, Riggs AD, Yu H (2012) Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci U S A 109(20):7765-7769
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.20
, pp. 7765-7769
-
-
Lee, H.1
Zhang, P.2
Herrmann, A.3
Yang, C.4
Xin, H.5
Wang, Z.6
Hoon, D.S.7
Forman, S.J.8
Jove, R.9
Riggs, A.D.10
Yu, H.11
-
40
-
-
84855968457
-
Early-stage formation of an epigenetic field defect in a mouse colitis model, and non-essential roles of T- and B-cells in DNA methylation induction
-
21685942
-
Katsurano M, Niwa T, Yasui Y, Shigematsu Y, Yamashita S, Takeshima H, Lee MS, Kim YJ, Tanaka T, Ushijima T (2012) Early-stage formation of an epigenetic field defect in a mouse colitis model, and non-essential roles of T- and B-cells in DNA methylation induction. Oncogene 31(3):342-351
-
(2012)
Oncogene
, vol.31
, Issue.3
, pp. 342-351
-
-
Katsurano, M.1
Niwa, T.2
Yasui, Y.3
Shigematsu, Y.4
Yamashita, S.5
Takeshima, H.6
Lee, M.S.7
Kim, Y.J.8
Tanaka, T.9
Ushijima, T.10
-
41
-
-
84896760044
-
Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes
-
24469454 3945349
-
Haseeb A, Makki MS, Haqqi TM (2014) Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes. J Biol Chem 289(10):6877-6885
-
(2014)
J Biol Chem
, vol.289
, Issue.10
, pp. 6877-6885
-
-
Haseeb, A.1
Makki, M.S.2
Haqqi, T.M.3
-
42
-
-
84964255539
-
Jansen JH (2015) 5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer
-
Kroeze LI, van der Reijden BA (1855) Jansen JH (2015) 5-Hydroxymethylcytosine: an epigenetic mark frequently deregulated in cancer. Biochim Biophys Acta 2:144-154
-
(1855)
Biochim Biophys Acta
, vol.2
, pp. 144-154
-
-
Kroeze, L.I.1
Van Der Reijden, B.A.2
-
43
-
-
33847070442
-
The role of chromatin during transcription
-
17320508
-
Li B, Carey M, Workman JL (2007) The role of chromatin during transcription. Cell 128(4):707-719
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
44
-
-
77957154350
-
Throwing the cancer switch: Reciprocal roles of polycomb and trithorax proteins
-
20865010 4068012
-
Mills AA (2010) Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat Rev Cancer 10(10):669-682
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.10
, pp. 669-682
-
-
Mills, A.A.1
-
45
-
-
84899482505
-
What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory
-
24755934
-
Steffen PA, Ringrose L (2014) What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory. Nat Rev Mol Cell Biol 15(5):340-356
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, Issue.5
, pp. 340-356
-
-
Steffen, P.A.1
Ringrose, L.2
-
46
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
17320510
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G (2007) Genome regulation by polycomb and trithorax proteins. Cell 128(4):735-745
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
47
-
-
65349151439
-
Biochemical mechanisms of gene regulation by polycomb group protein complexes
-
19345089
-
Muller J, Verrijzer P (2009) Biochemical mechanisms of gene regulation by polycomb group protein complexes. Curr Opin Genet Dev 19(2):150-158
-
(2009)
Curr Opin Genet Dev
, vol.19
, Issue.2
, pp. 150-158
-
-
Muller, J.1
Verrijzer, P.2
-
48
-
-
70349469565
-
Mechanisms of polycomb gene silencing: Knowns and unknowns
-
19738629
-
Simon JA, Kingston RE (2009) Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 10(10):697-708
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.10
, pp. 697-708
-
-
Simon, J.A.1
Kingston, R.E.2
-
49
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
18931660
-
Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, Rappsilber J, Lerdrup M, Helin K (2008) A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol 10(11):1291-1300
-
(2008)
Nat Cell Biol
, vol.10
, Issue.11
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
Gehani, S.S.5
Monrad, A.6
Rappsilber, J.7
Lerdrup, M.8
Helin, K.9
-
50
-
-
0036143654
-
P38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment
-
11743587
-
Saccani S, Pantano S, Natoli G (2002) p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 3(1):69-75
-
(2002)
Nat Immunol
, vol.3
, Issue.1
, pp. 69-75
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
51
-
-
0037497184
-
A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression
-
12789343
-
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS (2003) A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature 423(6940):659-663
-
(2003)
Nature
, vol.423
, Issue.6940
, pp. 659-663
-
-
Anest, V.1
Hanson, J.L.2
Cogswell, P.C.3
Steinbrecher, K.A.4
Strahl, B.D.5
Baldwin, A.S.6
-
52
-
-
79961023271
-
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
-
McDonald OG, Wu H, Timp W, Doi A, Feinberg AP (2011) Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition. Nat Struct Mol Biol 18(8):867-874
-
(2011)
Nat Struct Mol Biol
, vol.18
, Issue.8
, pp. 867-874
-
-
McDonald, O.G.1
Wu, H.2
Timp, W.3
Doi, A.4
Feinberg, A.P.5
-
53
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
20393566 3049919
-
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464(7291):1071-1076
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
Tsai, M.C.7
Hung, T.8
Argani, P.9
Rinn, J.L.10
Wang, Y.11
Brzoska, P.12
Kong, B.13
Li, R.14
West, R.B.15
Van De Vijver, M.J.16
Sukumar, S.17
Chang, H.Y.18
-
54
-
-
84911377275
-
Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract
-
25447409
-
Liu Y, Luo F, Xu Y, Wang B, Zhao Y, Xu W, Shi L, Lu X, Liu Q (2015) Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract. Toxicol Appl Pharmacol 282(1):9-19
-
(2015)
Toxicol Appl Pharmacol
, vol.282
, Issue.1
, pp. 9-19
-
-
Liu, Y.1
Luo, F.2
Xu, Y.3
Wang, B.4
Zhao, Y.5
Xu, W.6
Shi, L.7
Lu, X.8
Liu, Q.9
-
55
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
20797623 2929389
-
Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K (2010) STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 39(4):493-506
-
(2010)
Mol Cell
, vol.39
, Issue.4
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
Bulyk, M.L.4
Struhl, K.5
-
56
-
-
84896713700
-
A model for the epigenetic switch linking inflammation to cell transformation: Deterministic and stochastic approaches
-
24499937 3907303
-
Gerard C, Gonze D, Lemaigre F, Novak B (2014) A model for the epigenetic switch linking inflammation to cell transformation: deterministic and stochastic approaches. PLoS Comput Biol 10(1):e1003455
-
(2014)
PLoS Comput Biol
, vol.10
, Issue.1
, pp. e1003455
-
-
Gerard, C.1
Gonze, D.2
Lemaigre, F.3
Novak, B.4
-
57
-
-
33745686647
-
Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line
-
16597643
-
Fenton JI, Hursting SD, Perkins SN, Hord NG (2006) Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. Carcinogenesis 27(7):1507-1515
-
(2006)
Carcinogenesis
, vol.27
, Issue.7
, pp. 1507-1515
-
-
Fenton, J.I.1
Hursting, S.D.2
Perkins, S.N.3
Hord, N.G.4
-
58
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
19185845 2667107
-
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L, Karin M (2009) IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15(2):103-113
-
(2009)
Cancer Cell
, vol.15
, Issue.2
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
Karin, M.11
-
59
-
-
58649101347
-
Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
19185844
-
Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M, Greten FR (2009) gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15(2):91-102
-
(2009)
Cancer Cell
, vol.15
, Issue.2
, pp. 91-102
-
-
Bollrath, J.1
Phesse, T.J.2
Von Burstin, V.A.3
Putoczki, T.4
Bennecke, M.5
Bateman, T.6
Nebelsiek, T.7
Lundgren-May, T.8
Canli, O.9
Schwitalla, S.10
Matthews, V.11
Schmid, R.M.12
Kirchner, T.13
Arkan, M.C.14
Ernst, M.15
Greten, F.R.16
-
60
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
15294155
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M (2004) IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118(3):285-296
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
61
-
-
32044447161
-
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
-
16469705
-
Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, Liu YC, Karin M (2006) The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 124(3):601-613
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 601-613
-
-
Chang, L.1
Kamata, H.2
Solinas, G.3
Luo, J.L.4
Maeda, S.5
Venuprasad, K.6
Liu, Y.C.7
Karin, M.8
-
62
-
-
84858446579
-
MicroRNAs and their targets: Recognition, regulation and an emerging reciprocal relationship
-
22411466
-
Pasquinelli AE (2012) MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat Rev Genet 13(4):271-282
-
(2012)
Nat Rev Genet
, vol.13
, Issue.4
, pp. 271-282
-
-
Pasquinelli, A.E.1
-
63
-
-
84859920413
-
MicroRNA in cancer: New hopes for antineoplastic chemotherapy
-
22348396 3339552
-
Di Leva G, Briskin D, Croce CM (2012) MicroRNA in cancer: new hopes for antineoplastic chemotherapy. Ups J Med Sci 117(2):202-216
-
(2012)
Ups J Med Sci
, vol.117
, Issue.2
, pp. 202-216
-
-
Di Leva, G.1
Briskin, D.2
Croce, C.M.3
-
65
-
-
78649378267
-
MicroRNA functions in stress responses
-
20965416 2996264
-
Leung AK, Sharp PA (2010) MicroRNA functions in stress responses. Mol Cell 40(2):205-215
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 205-215
-
-
Leung, A.K.1
Sharp, P.A.2
-
66
-
-
84860324470
-
Roles for microRNAs in conferring robustness to biological processes
-
22541426 3351105
-
Ebert MS, Sharp PA (2012) Roles for microRNAs in conferring robustness to biological processes. Cell 149(3):515-524
-
(2012)
Cell
, vol.149
, Issue.3
, pp. 515-524
-
-
Ebert, M.S.1
Sharp, P.A.2
-
67
-
-
84883805211
-
The role of miRNAs in regulating gene expression networks
-
23500488 3757117
-
Gurtan AM, Sharp PA (2013) The role of miRNAs in regulating gene expression networks. J Mol Biol 425(19):3582-3600
-
(2013)
J Mol Biol
, vol.425
, Issue.19
, pp. 3582-3600
-
-
Gurtan, A.M.1
Sharp, P.A.2
-
68
-
-
85010834629
-
Exosomic microRNAs in the Tumor Microenvironment
-
Neviani P, Fabbri M (2015) Exosomic microRNAs in the Tumor Microenvironment. Front Med (Lausanne) 2:47
-
(2015)
Front Med (Lausanne)
, vol.2
, pp. 47
-
-
Neviani, P.1
Fabbri, M.2
-
69
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
17890317 2000384
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G, Morrison CD, Chan KK, Marcucci G, Calin GA, Huebner K, Croce CM (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 104(40):15805-15810
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.40
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
Liu, S.7
Alder, H.8
Costinean, S.9
Fernandez-Cymering, C.10
Volinia, S.11
Guler, G.12
Morrison, C.D.13
Chan, K.K.14
Marcucci, G.15
Calin, G.A.16
Huebner, K.17
Croce, C.M.18
-
70
-
-
64949190804
-
MiR-449a targets HDAC-1 and induces growth arrest in prostate cancer
-
19252524
-
Noonan EJ, Place RF, Pookot D, Basak S, Whitson JM, Hirata H, Giardina C, Dahiya R (2009) miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene 28(14):1714-1724
-
(2009)
Oncogene
, vol.28
, Issue.14
, pp. 1714-1724
-
-
Noonan, E.J.1
Place, R.F.2
Pookot, D.3
Basak, S.4
Whitson, J.M.5
Hirata, H.6
Giardina, C.7
Dahiya, R.8
-
71
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
19008416 2684823
-
Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM (2008) Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322(5908):1695-1699
-
(2008)
Science
, vol.322
, Issue.5908
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
Laxman, B.7
Cao, X.8
Jing, X.9
Ramnarayanan, K.10
Brenner, J.C.11
Yu, J.12
Kim, J.H.13
Han, B.14
Tan, P.15
Kumar-Sinha, C.16
Lonigro, R.J.17
Palanisamy, N.18
Maher, C.A.19
Chinnaiyan, A.M.20
more..
-
72
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
19665978 2731699
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, Diehn M, Liu H, Panula SP, Chiao E, Dirbas FM, Somlo G, Pera RA, Lao K, Clarke MF (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138(3):592-603
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
Diehn, M.7
Liu, H.8
Panula, S.P.9
Chiao, E.10
Dirbas, F.M.11
Somlo, G.12
Pera, R.A.13
Lao, K.14
Clarke, M.F.15
-
73
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
18719384
-
Lodygin D, Tarasov V, Epanchintsev A, Berking C, Knyazeva T, Korner H, Knyazev P, Diebold J, Hermeking H (2008) Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7(16):2591-2600
-
(2008)
Cell Cycle
, vol.7
, Issue.16
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
Berking, C.4
Knyazeva, T.5
Korner, H.6
Knyazev, P.7
Diebold, J.8
Hermeking, H.9
-
74
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
22898542
-
Hermeking H (2012) MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 12(9):613-626
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.9
, pp. 613-626
-
-
Hermeking, H.1
-
75
-
-
36349036470
-
Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor
-
17766920
-
Inouye S, Fujimoto M, Nakamura T, Takaki E, Hayashida N, Hai T, Nakai A (2007) Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor. J Biol Chem 282(45):33210-33217
-
(2007)
J Biol Chem
, vol.282
, Issue.45
, pp. 33210-33217
-
-
Inouye, S.1
Fujimoto, M.2
Nakamura, T.3
Takaki, E.4
Hayashida, N.5
Hai, T.6
Nakai, A.7
-
76
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
2470152
-
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A et al (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244(4905):707-712
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
77
-
-
79959917275
-
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis
-
21518778 3129398
-
Hartman ZC, Yang XY, Glass O, Lei G, Osada T, Dave SS, Morse MA, Clay TM, Lyerly HK (2011) HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis. Cancer Res 71(13):4380-4391
-
(2011)
Cancer Res
, vol.71
, Issue.13
, pp. 4380-4391
-
-
Hartman, Z.C.1
Yang, X.Y.2
Glass, O.3
Lei, G.4
Osada, T.5
Dave, S.S.6
Morse, M.A.7
Clay, T.M.8
Lyerly, H.K.9
-
78
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
16236738
-
Romond EH, Perez EA, Bryant J, Suman VJ, Geyer CE Jr, Davidson NE, Tan-Chiu E, Martino S, Paik S, Kaufman PA, Swain SM, Pisansky TM, Fehrenbacher L, Kutteh LA, Vogel VG, Visscher DW, Yothers G, Jenkins RB, Brown AM, Dakhil SR, Mamounas EP, Lingle WL, Klein PM, Ingle JN, Wolmark N (2005) Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353(16):1673-1684
-
(2005)
N Engl J Med
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer, C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
79
-
-
84865401715
-
Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population
-
22819326 3432419
-
Korkaya H, Kim GI, Davis A, Malik F, Henry NL, Ithimakin S, Quraishi AA, Tawakkol N, D'Angelo R, Paulson AK, Chung S, Luther T, Paholak HJ, Liu S, Hassan KA, Zen Q, Clouthier SG, Wicha MS (2012) Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population. Mol Cell 47(4):570-584
-
(2012)
Mol Cell
, vol.47
, Issue.4
, pp. 570-584
-
-
Korkaya, H.1
Kim, G.I.2
Davis, A.3
Malik, F.4
Henry, N.L.5
Ithimakin, S.6
Quraishi, A.A.7
Tawakkol, N.8
D'Angelo, R.9
Paulson, A.K.10
Chung, S.11
Luther, T.12
Paholak, H.J.13
Liu, S.14
Hassan, K.A.15
Zen, Q.16
Clouthier, S.G.17
Wicha, M.S.18
-
80
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
21220315 3029760
-
Iliopoulos D, Hirsch HA, Wang G, Struhl K (2011) Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci USA 108(4):1397-1402
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.4
, pp. 1397-1402
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Wang, G.3
Struhl, K.4
-
81
-
-
84886498002
-
NF-kappaB-mediated inflammation leading to EMT via miR-200c is involved in cell transformation induced by cigarette smoke extract
-
23824089
-
Zhao Y, Xu Y, Li Y, Xu W, Luo F, Wang B, Pang Y, Xiang Q, Zhou J, Wang X, Liu Q (2013) NF-kappaB-mediated inflammation leading to EMT via miR-200c is involved in cell transformation induced by cigarette smoke extract. Toxicol Sci 135(2):265-276
-
(2013)
Toxicol Sci
, vol.135
, Issue.2
, pp. 265-276
-
-
Zhao, Y.1
Xu, Y.2
Li, Y.3
Xu, W.4
Luo, F.5
Wang, B.6
Pang, Y.7
Xiang, Q.8
Zhou, J.9
Wang, X.10
Liu, Q.11
-
82
-
-
84881303278
-
Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition
-
23318420
-
Guo L, Chen C, Shi M, Wang F, Chen X, Diao D, Hu M, Yu M, Qian L, Guo N (2013) Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition. Oncogene 32(45):5272-5282
-
(2013)
Oncogene
, vol.32
, Issue.45
, pp. 5272-5282
-
-
Guo, L.1
Chen, C.2
Shi, M.3
Wang, F.4
Chen, X.5
Diao, D.6
Hu, M.7
Yu, M.8
Qian, L.9
Guo, N.10
-
83
-
-
84894495362
-
STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-kappaB to IL-6 signaling axis and STAT3-driven cancer phenotypes
-
Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA (2014) STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-kappaB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal 7 (310):ra11
-
(2014)
Sci Signal
, vol.7
, Issue.310
, pp. ra11
-
-
Xiang, M.1
Birkbak, N.J.2
Vafaizadeh, V.3
Walker, S.R.4
Yeh, J.E.5
Liu, S.6
Kroll, Y.7
Boldin, M.8
Taganov, K.9
Groner, B.10
Richardson, A.L.11
Frank, D.A.12
-
84
-
-
84893771246
-
SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model
-
24531711 4285772
-
Kim G, Ouzounova M, Quraishi AA, Davis A, Tawakkol N, Clouthier SG, Malik F, Paulson AK, D'Angelo RC, Korkaya S, Baker TL, Esen ES, Prat A, Liu S, Kleer CG, Thomas DG, Wicha MS, Korkaya H (2015) SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model. Oncogene 34(6):671-680
-
(2015)
Oncogene
, vol.34
, Issue.6
, pp. 671-680
-
-
Kim, G.1
Ouzounova, M.2
Quraishi, A.A.3
Davis, A.4
Tawakkol, N.5
Clouthier, S.G.6
Malik, F.7
Paulson, A.K.8
D'Angelo, R.C.9
Korkaya, S.10
Baker, T.L.11
Esen, E.S.12
Prat, A.13
Liu, S.14
Kleer, C.G.15
Thomas, D.G.16
Wicha, M.S.17
Korkaya, H.18
-
85
-
-
84859710888
-
An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice
-
22406536 3314459
-
Daniluk J, Liu Y, Deng D, Chu J, Huang H, Gaiser S, Cruz-Monserrate Z, Wang H, Ji B, Logsdon CD (2012) An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest 122(4):1519-1528
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1519-1528
-
-
Daniluk, J.1
Liu, Y.2
Deng, D.3
Chu, J.4
Huang, H.5
Gaiser, S.6
Cruz-Monserrate, Z.7
Wang, H.8
Ji, B.9
Logsdon, C.D.10
-
86
-
-
84879469809
-
The gastrointestinal tumor microenvironment
-
23583733 4012393
-
Quante M, Varga J, Wang TC, Greten FR (2013) The gastrointestinal tumor microenvironment. Gastroenterology 145(1):63-78
-
(2013)
Gastroenterology
, vol.145
, Issue.1
, pp. 63-78
-
-
Quante, M.1
Varga, J.2
Wang, T.C.3
Greten, F.R.4
-
87
-
-
84898005710
-
Interleukin 6 promotes endometrial cancer growth through an autocrine feedback loop involving ERK-NF-kappaB signaling pathway
-
24582558
-
Che Q, Liu BY, Wang FY, He YY, Lu W, Liao Y, Gu W, Wan XP (2014) Interleukin 6 promotes endometrial cancer growth through an autocrine feedback loop involving ERK-NF-kappaB signaling pathway. Biochem Biophys Res Commun 446(1):167-172
-
(2014)
Biochem Biophys Res Commun
, vol.446
, Issue.1
, pp. 167-172
-
-
Che, Q.1
Liu, B.Y.2
Wang, F.Y.3
He, Y.Y.4
Lu, W.5
Liao, Y.6
Gu, W.7
Wan, X.P.8
-
88
-
-
79956126860
-
IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR
-
21258401 3112005
-
Rojas A, Liu G, Coleman I, Nelson PS, Zhang M, Dash R, Fisher PB, Plymate SR, Wu JD (2011) IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR. Oncogene 30(20):2345-2355
-
(2011)
Oncogene
, vol.30
, Issue.20
, pp. 2345-2355
-
-
Rojas, A.1
Liu, G.2
Coleman, I.3
Nelson, P.S.4
Zhang, M.5
Dash, R.6
Fisher, P.B.7
Plymate, S.R.8
Wu, J.D.9
-
89
-
-
49449106856
-
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
-
18759290
-
Nile CJ, Read RC, Akil M, Duff GW, Wilson AG (2008) Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 58(9):2686-2693
-
(2008)
Arthritis Rheum
, vol.58
, Issue.9
, pp. 2686-2693
-
-
Nile, C.J.1
Read, R.C.2
Akil, M.3
Duff, G.W.4
Wilson, A.G.5
-
90
-
-
78549283836
-
Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells
-
21092249 3002335
-
D'Anello L, Sansone P, Storci G, Mitrugno V, D'Uva G, Chieco P, Bonafe M (2010) Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells. Mol Cancer 9:300
-
(2010)
Mol Cancer
, vol.9
, pp. 300
-
-
D'Anello, L.1
Sansone, P.2
Storci, G.3
Mitrugno, V.4
D'Uva, G.5
Chieco, P.6
Bonafe, M.7
-
91
-
-
0030034383
-
Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines
-
9816109
-
Chiu JJ, Sgagias MK, Cowan KH (1996) Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines. Clin Cancer Res 2(1):215-221
-
(1996)
Clin Cancer Res
, vol.2
, Issue.1
, pp. 215-221
-
-
Chiu, J.J.1
Sgagias, M.K.2
Cowan, K.H.3
-
92
-
-
84857919158
-
Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs
-
21553120
-
Guttilla IK, Phoenix KN, Hong X, Tirnauer JS, Claffey KP, White BA (2012) Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs. Breast Cancer Res Treat 132(1):75-85
-
(2012)
Breast Cancer Res Treat
, vol.132
, Issue.1
, pp. 75-85
-
-
Guttilla, I.K.1
Phoenix, K.N.2
Hong, X.3
Tirnauer, J.S.4
Claffey, K.P.5
White, B.A.6
-
93
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
17615358
-
Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM, Karin M (2007) Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317(5834):121-124
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
Karin, M.7
-
94
-
-
83255162659
-
An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
-
22153071 3251960
-
Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D (2011) An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell 147(6):1233-1247
-
(2011)
Cell
, vol.147
, Issue.6
, pp. 1233-1247
-
-
Hatziapostolou, M.1
Polytarchou, C.2
Aggelidou, E.3
Drakaki, A.4
Poultsides, G.A.5
Jaeger, S.A.6
Ogata, H.7
Karin, M.8
Struhl, K.9
Hadzopoulou-Cladaras, M.10
Iliopoulos, D.11
-
95
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
2188735
-
Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61(5):759-767
-
(1990)
Cell
, vol.61
, Issue.5
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
96
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
21376230
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646-674
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
97
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
18555778
-
Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS (2008) Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133(6):1019-1031
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
Van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
98
-
-
27744487376
-
Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line
-
16271952
-
Cowell JK, LaDuca J, Rossi MR, Burkhardt T, Nowak NJ, Matsui S (2005) Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line. Cancer Genet Cytogenet 163(1):23-29
-
(2005)
Cancer Genet Cytogenet
, vol.163
, Issue.1
, pp. 23-29
-
-
Cowell, J.K.1
LaDuca, J.2
Rossi, M.R.3
Burkhardt, T.4
Nowak, N.J.5
Matsui, S.6
-
99
-
-
70350784147
-
Transformation locked in a loop
-
19914159
-
Drost J, Agami R (2009) Transformation locked in a loop. Cell 139(4):654-656
-
(2009)
Cell
, vol.139
, Issue.4
, pp. 654-656
-
-
Drost, J.1
Agami, R.2
-
101
-
-
33745684527
-
Metastasis: A question of life or death
-
16723991
-
Mehlen P, Puisieux A (2006) Metastasis: a question of life or death. Nat Rev Cancer 6(6):449-458
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.6
, pp. 449-458
-
-
Mehlen, P.1
Puisieux, A.2
-
102
-
-
50849090319
-
Macrophages define the invasive microenvironment in breast cancer
-
18467655 2516896
-
Pollard JW (2008) Macrophages define the invasive microenvironment in breast cancer. J Leukoc Biol 84(3):623-630
-
(2008)
J Leukoc Biol
, vol.84
, Issue.3
, pp. 623-630
-
-
Pollard, J.W.1
-
103
-
-
69249221254
-
Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells
-
19581928
-
Sullivan NJ, Sasser AK, Axel AE, Vesuna F, Raman V, Ramirez N, Oberyszyn TM, Hall BM (2009) Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. Oncogene 28(33):2940-2947
-
(2009)
Oncogene
, vol.28
, Issue.33
, pp. 2940-2947
-
-
Sullivan, N.J.1
Sasser, A.K.2
Axel, A.E.3
Vesuna, F.4
Raman, V.5
Ramirez, N.6
Oberyszyn, T.M.7
Hall, B.M.8
-
104
-
-
33845865825
-
Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
-
17186030
-
Yu H, Kortylewski M, Pardoll D (2007) Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 7(1):41-51
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.1
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
105
-
-
65349092794
-
Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
-
19411070 2881229
-
Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP (2009) Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 15(5):416-428
-
(2009)
Cancer Cell
, vol.15
, Issue.5
, pp. 416-428
-
-
Wu, Y.1
Deng, J.2
Rychahou, P.G.3
Qiu, S.4
Evers, B.M.5
Zhou, B.P.6
-
106
-
-
84055207487
-
IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway
-
21976712 3243808
-
Yadav A, Kumar B, Datta J, Teknos TN, Kumar P (2011) IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway. Mol Cancer Res 9(12):1658-1667
-
(2011)
Mol Cancer Res
, vol.9
, Issue.12
, pp. 1658-1667
-
-
Yadav, A.1
Kumar, B.2
Datta, J.3
Teknos, T.N.4
Kumar, P.5
-
107
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
19308067
-
Nguyen DX, Bos PD, Massague J (2009) Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9(4):274-284
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
108
-
-
68749109536
-
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
-
19668347 2721818
-
Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J, Lang RA, Pollard JW (2009) A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS ONE 4(8):e6562
-
(2009)
PLoS ONE
, vol.4
, Issue.8
, pp. e6562
-
-
Qian, B.1
Deng, Y.2
Im, J.H.3
Muschel, R.J.4
Zou, Y.5
Li, J.6
Lang, R.A.7
Pollard, J.W.8
-
109
-
-
47949090079
-
The role of myeloid cells in the promotion of tumour angiogenesis
-
18633355
-
Murdoch C, Muthana M, Coffelt SB, Lewis CE (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 8(8):618-631
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.8
, pp. 618-631
-
-
Murdoch, C.1
Muthana, M.2
Coffelt, S.B.3
Lewis, C.E.4
-
110
-
-
84928077532
-
Macrophages and Therapeutic Resistance in Cancer
-
25858805
-
Ruffell B, Coussens LM (2015) Macrophages and Therapeutic Resistance in Cancer. Cancer Cell 27(4):462-472
-
(2015)
Cancer Cell
, vol.27
, Issue.4
, pp. 462-472
-
-
Ruffell, B.1
Coussens, L.M.2
-
111
-
-
84902546715
-
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
-
24898549
-
Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, Rey-Giraud F, Pradel LP, Feuerhake F, Klaman I, Jones T, Jucknischke U, Scheiblich S, Kaluza K, Gorr IH, Walz A, Abiraj K, Cassier PA, Sica A, Gomez-Roca C, de Visser KE, Italiano A, Le Tourneau C, Delord JP, Levitsky H, Blay JY, Ruttinger D (2014) Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell 25(6):846-859
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 846-859
-
-
Ries, C.H.1
Cannarile, M.A.2
Hoves, S.3
Benz, J.4
Wartha, K.5
Runza, V.6
Rey-Giraud, F.7
Pradel, L.P.8
Feuerhake, F.9
Klaman, I.10
Jones, T.11
Jucknischke, U.12
Scheiblich, S.13
Kaluza, K.14
Gorr, I.H.15
Walz, A.16
Abiraj, K.17
Cassier, P.A.18
Sica, A.19
Gomez-Roca, C.20
De Visser, K.E.21
Italiano, A.22
Le Tourneau, C.23
Delord, J.P.24
Levitsky, H.25
Blay, J.Y.26
Ruttinger, D.27
more..
-
112
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
21654748 3208506
-
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, Kaiser EA, Snyder LA, Pollard JW (2011) CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 475(7355):222-225
-
(2011)
Nature
, vol.475
, Issue.7355
, pp. 222-225
-
-
Qian, B.Z.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
Kaiser, E.A.7
Snyder, L.A.8
Pollard, J.W.9
-
113
-
-
84874629992
-
MiR-126 and miR-126repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis
-
23396050 3672398
-
Zhang Y, Yang P, Sun T, Li D, Xu X, Rui Y, Li C, Chong M, Ibrahim T, Mercatali L, Amadori D, Lu X, Xie D, Li QJ, Wang XF (2013) miR-126 and miR-126repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol 15(3):284-294
-
(2013)
Nat Cell Biol
, vol.15
, Issue.3
, pp. 284-294
-
-
Zhang, Y.1
Yang, P.2
Sun, T.3
Li, D.4
Xu, X.5
Rui, Y.6
Li, C.7
Chong, M.8
Ibrahim, T.9
Mercatali, L.10
Amadori, D.11
Lu, X.12
Xie, D.13
Li, Q.J.14
Wang, X.F.15
-
114
-
-
84863756518
-
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway
-
22789541
-
Wolf MJ, Hoos A, Bauer J, Boettcher S, Knust M, Weber A, Simonavicius N, Schneider C, Lang M, Sturzl M, Croner RS, Konrad A, Manz MG, Moch H, Aguzzi A, van Loo G, Pasparakis M, Prinz M, Borsig L, Heikenwalder M (2012) Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway. Cancer Cell 22(1):91-105
-
(2012)
Cancer Cell
, vol.22
, Issue.1
, pp. 91-105
-
-
Wolf, M.J.1
Hoos, A.2
Bauer, J.3
Boettcher, S.4
Knust, M.5
Weber, A.6
Simonavicius, N.7
Schneider, C.8
Lang, M.9
Sturzl, M.10
Croner, R.S.11
Konrad, A.12
Manz, M.G.13
Moch, H.14
Aguzzi, A.15
Van Loo, G.16
Pasparakis, M.17
Prinz, M.18
Borsig, L.19
Heikenwalder, M.20
more..
-
115
-
-
84877679070
-
Tumor endothelial cells
-
22393533 3282494
-
Dudley AC (2012) Tumor endothelial cells. Cold Spring Harb Perspect Med 2(3):a006536
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, Issue.3
, pp. a006536
-
-
Dudley, A.C.1
-
116
-
-
79959944026
-
Antiangiogenic therapy, hypoxia, and metastasis: Risky liaisons, or not?
-
21629216
-
De Bock K, Mazzone M, Carmeliet P (2011) Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? Nat Rev Clin Oncol 8(7):393-404
-
(2011)
Nat Rev Clin Oncol
, vol.8
, Issue.7
, pp. 393-404
-
-
De Bock, K.1
Mazzone, M.2
Carmeliet, P.3
-
117
-
-
73349128755
-
Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes
-
19779041
-
Laubli H, Spanaus KS, Borsig L (2009) Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes. Blood 114(20):4583-4591
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4583-4591
-
-
Laubli, H.1
Spanaus, K.S.2
Borsig, L.3
-
118
-
-
34748914299
-
Evolving functions of endothelial cells in inflammation
-
17893694
-
Pober JS, Sessa WC (2007) Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7(10):803-815
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.10
, pp. 803-815
-
-
Pober, J.S.1
Sessa, W.C.2
-
119
-
-
0028179102
-
Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis
-
7515767
-
Okahara H, Yagita H, Miyake K, Okumura K (1994) Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis. Cancer Res 54(12):3233-3236
-
(1994)
Cancer Res
, vol.54
, Issue.12
, pp. 3233-3236
-
-
Okahara, H.1
Yagita, H.2
Miyake, K.3
Okumura, K.4
-
120
-
-
38549159585
-
The selectin-selectin ligand axis in tumor progression
-
18180878
-
Witz IP (2008) The selectin-selectin ligand axis in tumor progression. Cancer Metastasis Rev 27(1):19-30
-
(2008)
Cancer Metastasis Rev
, vol.27
, Issue.1
, pp. 19-30
-
-
Witz, I.P.1
-
121
-
-
33845982933
-
Involvement of p38alpha mitogen-activated protein kinase in lung metastasis of tumor cells
-
17028194
-
Matsuo Y, Amano S, Furuya M, Namiki K, Sakurai K, Nishiyama M, Sudo T, Tatsumi K, Kuriyama T, Kimura S, Kasuya Y (2006) Involvement of p38alpha mitogen-activated protein kinase in lung metastasis of tumor cells. J Biol Chem 281(48):36767-36775
-
(2006)
J Biol Chem
, vol.281
, Issue.48
, pp. 36767-36775
-
-
Matsuo, Y.1
Amano, S.2
Furuya, M.3
Namiki, K.4
Sakurai, K.5
Nishiyama, M.6
Sudo, T.7
Tatsumi, K.8
Kuriyama, T.9
Kimura, S.10
Kasuya, Y.11
-
122
-
-
0034660854
-
Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression
-
10919677
-
Kobayashi K, Matsumoto S, Morishima T, Kawabe T, Okamoto T (2000) Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Res 60(14):3978-3984
-
(2000)
Cancer Res
, vol.60
, Issue.14
, pp. 3978-3984
-
-
Kobayashi, K.1
Matsumoto, S.2
Morishima, T.3
Kawabe, T.4
Okamoto, T.5
-
123
-
-
84925023408
-
Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer
-
25411357
-
Kurashige J, Mima K, Sawada G, Takahashi Y, Eguchi H, Sugimachi K, Mori M, Yanagihara K, Yashiro M, Hirakawa K, Baba H, Mimori K (2015) Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer. Carcinogenesis 36(1):133-141
-
(2015)
Carcinogenesis
, vol.36
, Issue.1
, pp. 133-141
-
-
Kurashige, J.1
Mima, K.2
Sawada, G.3
Takahashi, Y.4
Eguchi, H.5
Sugimachi, K.6
Mori, M.7
Yanagihara, K.8
Yashiro, M.9
Hirakawa, K.10
Baba, H.11
Mimori, K.12
-
124
-
-
84883377982
-
Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma
-
23993096 3974915
-
Zhang XH, Jin X, Malladi S, Zou Y, Wen YH, Brogi E, Smid M, Foekens JA, Massague J (2013) Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell 154(5):1060-1073
-
(2013)
Cell
, vol.154
, Issue.5
, pp. 1060-1073
-
-
Zhang, X.H.1
Jin, X.2
Malladi, S.3
Zou, Y.4
Wen, Y.H.5
Brogi, E.6
Smid, M.7
Foekens, J.A.8
Massague, J.9
-
125
-
-
84859710342
-
Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change
-
22514714 3325931
-
Tyan SW, Hsu CH, Peng KL, Chen CC, Kuo WH, Lee EY, Shew JY, Chang KJ, Juan LJ, Lee WH (2012) Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change. PLoS ONE 7(4):e35128
-
(2012)
PLoS ONE
, vol.7
, Issue.4
, pp. e35128
-
-
Tyan, S.W.1
Hsu, C.H.2
Peng, K.L.3
Chen, C.C.4
Kuo, W.H.5
Lee, E.Y.6
Shew, J.Y.7
Chang, K.J.8
Juan, L.J.9
Lee, W.H.10
-
126
-
-
33646576169
-
Matrix metalloproteinases and tumor metastasis
-
16680569
-
Deryugina EI, Quigley JP (2006) Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25(1):9-34
-
(2006)
Cancer Metastasis Rev
, vol.25
, Issue.1
, pp. 9-34
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
127
-
-
0347383715
-
Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development
-
14612884 2394437
-
Hojilla CV, Mohammed FF, Khokha R (2003) Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development. Br J Cancer 89(10):1817-1821
-
(2003)
Br J Cancer
, vol.89
, Issue.10
, pp. 1817-1821
-
-
Hojilla, C.V.1
Mohammed, F.F.2
Khokha, R.3
-
128
-
-
0141988559
-
Molecular mechanisms of tumor invasion and metastasis: An integrated view
-
14601640
-
Cairns RA, Khokha R, Hill RP (2003) Molecular mechanisms of tumor invasion and metastasis: an integrated view. Curr Mol Med 3(7):659-671
-
(2003)
Curr Mol Med
, vol.3
, Issue.7
, pp. 659-671
-
-
Cairns, R.A.1
Khokha, R.2
Hill, R.P.3
-
129
-
-
84882450634
-
Epigenetic regulation of mmp-9 gene expression
-
23184252
-
Labrie M, St-Pierre Y (2013) Epigenetic regulation of mmp-9 gene expression. Cell Mol Life Sci 70(17):3109-3124
-
(2013)
Cell Mol Life Sci
, vol.70
, Issue.17
, pp. 3109-3124
-
-
Labrie, M.1
St-Pierre, Y.2
-
130
-
-
43049101599
-
The regulation of matrix metalloproteinases and their inhibitors
-
18258475
-
Clark IM, Swingler TE, Sampieri CL, Edwards DR (2008) The regulation of matrix metalloproteinases and their inhibitors. Int J Biochem Cell Biol 40(6-7):1362-1378
-
(2008)
Int J Biochem Cell Biol
, vol.40
, Issue.6-7
, pp. 1362-1378
-
-
Clark, I.M.1
Swingler, T.E.2
Sampieri, C.L.3
Edwards, D.R.4
-
131
-
-
80052269426
-
5-Aza-2′-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression
-
21170958
-
Couillard J, Esteve PO, Pradhan S, St-Pierre Y (2011) 5-Aza-2′-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression. Int J Cancer 129(9):2083-2092
-
(2011)
Int J Cancer
, vol.129
, Issue.9
, pp. 2083-2092
-
-
Couillard, J.1
Esteve, P.O.2
Pradhan, S.3
St-Pierre, Y.4
-
132
-
-
84885915873
-
Epithelial-mesenchymal plasticity in carcinoma metastasis
-
24142872 3814640
-
Tsai JH, Yang J (2013) Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev 27(20):2192-2206
-
(2013)
Genes Dev
, vol.27
, Issue.20
, pp. 2192-2206
-
-
Tsai, J.H.1
Yang, J.2
-
133
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
-
23201163
-
Ocana OH, Corcoles R, Fabra A, Moreno-Bueno G, Acloque H, Vega S, Barrallo-Gimeno A, Cano A, Nieto MA (2012) Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22(6):709-724
-
(2012)
Cancer Cell
, vol.22
, Issue.6
, pp. 709-724
-
-
Ocana, O.H.1
Corcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
Barrallo-Gimeno, A.7
Cano, A.8
Nieto, M.A.9
-
134
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
21663795 3930331
-
Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA (2011) Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 145(6):926-940
-
(2011)
Cell
, vol.145
, Issue.6
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
Kah, K.J.6
Bell, G.7
Guo, W.8
Rubin, J.9
Richardson, A.L.10
Weinberg, R.A.11
-
135
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Pa Gregory, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, Ma Vadas, Khew-Goodall Y, Goodall GJ (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10(5):593-601
-
(2008)
Nat Cell Biol
, vol.10
, Issue.5
, pp. 593-601
-
-
Pa, G.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Ma, V.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
136
-
-
84055184850
-
MiR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
-
22134354
-
Siemens H, Jackstadt R, Hunten S, Kaller M, Menssen A, Gotz U, Hermeking H (2011) miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle 10(24):4256-4271
-
(2011)
Cell Cycle
, vol.10
, Issue.24
, pp. 4256-4271
-
-
Siemens, H.1
Jackstadt, R.2
Hunten, S.3
Kaller, M.4
Menssen, A.5
Gotz, U.6
Hermeking, H.7
-
137
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
18483486 2396950
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9(6):582-589
-
(2008)
EMBO Rep
, vol.9
, Issue.6
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
Brabletz, T.7
-
138
-
-
84888875112
-
SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition
-
24185900 3844956
-
Hahn S, Jackstadt R, Siemens H, Hunten S, Hermeking H (2013) SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition. EMBO J 32(23):3079-3095
-
(2013)
EMBO J
, vol.32
, Issue.23
, pp. 3079-3095
-
-
Hahn, S.1
Jackstadt, R.2
Siemens, H.3
Hunten, S.4
Hermeking, H.5
-
139
-
-
84901704452
-
The p53/miR-34 axis in development and disease
-
24815299
-
Rokavec M, Li H, Jiang L, Hermeking H (2014) The p53/miR-34 axis in development and disease. J Mol Cell Biol 6(3):214-230
-
(2014)
J Mol Cell Biol
, vol.6
, Issue.3
, pp. 214-230
-
-
Rokavec, M.1
Li, H.2
Jiang, L.3
Hermeking, H.4
-
140
-
-
84865973348
-
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
-
22850877 3428095
-
Ahn YH, Gibbons DL, Chakravarti D, Creighton CJ, Rizvi ZH, Adams HP, Pertsemlidis A, Gregory PA, Wright JA, Goodall GJ, Flores ER, Kurie JM (2012) ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest 122(9):3170-3183
-
(2012)
J Clin Invest
, vol.122
, Issue.9
, pp. 3170-3183
-
-
Ahn, Y.H.1
Gibbons, D.L.2
Chakravarti, D.3
Creighton, C.J.4
Rizvi, Z.H.5
Adams, H.P.6
Pertsemlidis, A.7
Gregory, P.A.8
Wright, J.A.9
Goodall, G.J.10
Flores, E.R.11
Kurie, J.M.12
-
141
-
-
77649251655
-
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells
-
20084174 2805718
-
Vrba L, Jensen TJ, Garbe JC, Heimark RL, Cress AE, Dickinson S, Stampfer MR, Futscher BW (2010) Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. PLoS ONE 5(1):e8697
-
(2010)
PLoS ONE
, vol.5
, Issue.1
, pp. e8697
-
-
Vrba, L.1
Jensen, T.J.2
Garbe, J.C.3
Heimark, R.L.4
Cress, A.E.5
Dickinson, S.6
Stampfer, M.R.7
Futscher, B.W.8
-
142
-
-
79954576652
-
EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells
-
21363915 3078195
-
Tellez CS, Juri DE, Do K, Bernauer AM, Thomas CL, Damiani LA, Tessema M, Leng S, Belinsky SA (2011) EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res 71(8):3087-3097
-
(2011)
Cancer Res
, vol.71
, Issue.8
, pp. 3087-3097
-
-
Tellez, C.S.1
Juri, D.E.2
Do, K.3
Bernauer, A.M.4
Thomas, C.L.5
Damiani, L.A.6
Tessema, M.7
Leng, S.8
Belinsky, S.A.9
-
143
-
-
84897561550
-
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
-
24642471 3973098
-
Rokavec M, Oner MG, Li H, Jackstadt R, Jiang L, Lodygin D, Kaller M, Horst D, Ziegler PK, Schwitalla S, Slotta-Huspenina J, Bader FG, Greten FR, Hermeking H (2014) IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. J Clin Invest 124(4):1853-1867
-
(2014)
J Clin Invest
, vol.124
, Issue.4
, pp. 1853-1867
-
-
Rokavec, M.1
Oner, M.G.2
Li, H.3
Jackstadt, R.4
Jiang, L.5
Lodygin, D.6
Kaller, M.7
Horst, D.8
Ziegler, P.K.9
Schwitalla, S.10
Slotta-Huspenina, J.11
Bader, F.G.12
Greten, F.R.13
Hermeking, H.14
-
144
-
-
84931076559
-
Soluble IL6R represents a miR-34a target: Potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop
-
26091352 4546448
-
Li H, Rokavec M, Hermeking H (2015) Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop. Oncotarget 6(17):14026-14032
-
(2015)
Oncotarget
, vol.6
, Issue.17
, pp. 14026-14032
-
-
Li, H.1
Rokavec, M.2
Hermeking, H.3
-
145
-
-
79955470407
-
The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer
-
21145125
-
Chalaris A, Garbers C, Rabe B, Rose-John S, Scheller J (2011) The soluble Interleukin 6 receptor: generation and role in inflammation and cancer. Eur J Cell Biol 90(6-7):484-494
-
(2011)
Eur J Cell Biol
, vol.90
, Issue.6-7
, pp. 484-494
-
-
Chalaris, A.1
Garbers, C.2
Rabe, B.3
Rose-John, S.4
Scheller, J.5
-
146
-
-
5644252874
-
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
-
15485627
-
Becker C, Fantini MC, Schramm C, Lehr HA, Wirtz S, Nikolaev A, Burg J, Strand S, Kiesslich R, Huber S, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Galle PR, Blessing M, Rose-John S, Neurath MF (2004) TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 21(4):491-501
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 491-501
-
-
Becker, C.1
Fantini, M.C.2
Schramm, C.3
Lehr, H.A.4
Wirtz, S.5
Nikolaev, A.6
Burg, J.7
Strand, S.8
Kiesslich, R.9
Huber, S.10
Ito, H.11
Nishimoto, N.12
Yoshizaki, K.13
Kishimoto, T.14
Galle, P.R.15
Blessing, M.16
Rose-John, S.17
Neurath, M.F.18
-
147
-
-
78650949351
-
Interleukin 6/interleukin 6 receptor interaction and its role as a therapeutic target for treatment of cachexia and cancer
-
21156962
-
Weidle UH, Klostermann S, Eggle D, Kruger A (2010) Interleukin 6/interleukin 6 receptor interaction and its role as a therapeutic target for treatment of cachexia and cancer. Cancer Genomics Proteomics 7(6):287-302
-
(2010)
Cancer Genomics Proteomics
, vol.7
, Issue.6
, pp. 287-302
-
-
Weidle, U.H.1
Klostermann, S.2
Eggle, D.3
Kruger, A.4
-
148
-
-
84927610492
-
Interleukin-6 as a Therapeutic Target
-
25589616
-
Rossi JF, Lu ZY, Jourdan M, Klein B (2015) Interleukin-6 as a Therapeutic Target. Clin Cancer Res 21(6):1248-1257
-
(2015)
Clin Cancer Res
, vol.21
, Issue.6
, pp. 1248-1257
-
-
Rossi, J.F.1
Lu, Z.Y.2
Jourdan, M.3
Klein, B.4
-
149
-
-
84859731270
-
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
-
22406531 3314447
-
Dong C, Wu Y, Yao J, Wang Y, Yu Y, Rychahou PG, Evers BM, Zhou BP (2012) G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer. J Clin Invest 122(4):1469-1486
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1469-1486
-
-
Dong, C.1
Wu, Y.2
Yao, J.3
Wang, Y.4
Yu, Y.5
Rychahou, P.G.6
Evers, B.M.7
Zhou, B.P.8
-
150
-
-
84875220237
-
Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer
-
22562246 3703513
-
Dong C, Wu Y, Wang Y, Wang C, Kang T, Rychahou PG, Chi YI, Evers BM, Zhou BP (2013) Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer. Oncogene 32(11):1351-1362
-
(2013)
Oncogene
, vol.32
, Issue.11
, pp. 1351-1362
-
-
Dong, C.1
Wu, Y.2
Wang, Y.3
Wang, C.4
Kang, T.5
Rychahou, P.G.6
Chi, Y.I.7
Evers, B.M.8
Zhou, B.P.9
-
151
-
-
47949125993
-
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor
-
18519590 2493371
-
Herranz N, Pasini D, Diaz VM, Franci C, Gutierrez A, Dave N, Escriva M, Hernandez-Munoz I, Di Croce L, Helin K, Garcia de Herreros A, Peiro S (2008) Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol 28(15):4772-4781
-
(2008)
Mol Cell Biol
, vol.28
, Issue.15
, pp. 4772-4781
-
-
Herranz, N.1
Pasini, D.2
Diaz, V.M.3
Franci, C.4
Gutierrez, A.5
Dave, N.6
Escriva, M.7
Hernandez-Munoz, I.8
Di Croce, L.9
Helin, K.10
Garcia De Herreros, A.11
Peiro, S.12
-
152
-
-
77956547097
-
Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
-
20832727 2938080
-
Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K (2010) Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell 39(5):761-772
-
(2010)
Mol Cell
, vol.39
, Issue.5
, pp. 761-772
-
-
Iliopoulos, D.1
Lindahl-Allen, M.2
Polytarchou, C.3
Hirsch, H.A.4
Tsichlis, P.N.5
Struhl, K.6
-
153
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
19269371 2787236
-
Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R (2009) Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136(5):964-977
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
Isacson, O.11
Jaenisch, R.12
-
154
-
-
84885183807
-
Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq
-
23995732 4100556
-
Brady JJ, Li M, Suthram S, Jiang H, Wong WH, Blau HM (2013) Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq. Nat Cell Biol 15(10):1244-1252
-
(2013)
Nat Cell Biol
, vol.15
, Issue.10
, pp. 1244-1252
-
-
Brady, J.J.1
Li, M.2
Suthram, S.3
Jiang, H.4
Wong, W.H.5
Blau, H.M.6
-
155
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
16630819
-
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125(2):315-326
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
Jaenisch, R.11
Wagschal, A.12
Feil, R.13
Schreiber, S.L.14
Lander, E.S.15
-
156
-
-
84923337150
-
An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth
-
25370275
-
Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J (2014) An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun 5:5425
-
(2014)
Nat Commun
, vol.5
, pp. 5425
-
-
Shi, X.1
Zhang, Z.2
Zhan, X.3
Cao, M.4
Satoh, T.5
Akira, S.6
Shpargel, K.7
Magnuson, T.8
Li, Q.9
Wang, R.10
Wang, C.11
Ge, K.12
Wu, J.13
-
157
-
-
84892770469
-
Basal-like breast cancer: Update on clinicopathologic, immunohistochemical, and molecular features
-
24377810
-
Leidy J, Khan A, Kandil D (2014) Basal-like breast cancer: update on clinicopathologic, immunohistochemical, and molecular features. Arch Pathol Lab Med 138(1):37-43
-
(2014)
Arch Pathol Lab Med
, vol.138
, Issue.1
, pp. 37-43
-
-
Leidy, J.1
Khan, A.2
Kandil, D.3
-
159
-
-
84924249260
-
The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
-
25748930
-
Plaks V, Kong N, Werb Z (2015) The Cancer Stem Cell Niche: how Essential Is the Niche in Regulating Stemness of Tumor Cells? Cell Stem Cell 16(3):225-238
-
(2015)
Cell Stem Cell
, vol.16
, Issue.3
, pp. 225-238
-
-
Plaks, V.1
Kong, N.2
Werb, Z.3
-
160
-
-
35648983903
-
Inflammation and cancer: An ancient link with novel potentials
-
17893866
-
Hussain SP, Harris CC (2007) Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 121(11):2373-2380
-
(2007)
Int J Cancer
, vol.121
, Issue.11
, pp. 2373-2380
-
-
Hussain, S.P.1
Harris, C.C.2
-
161
-
-
76649145629
-
Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells
-
20124475
-
Niwa T, Tsukamoto T, Toyoda T, Mori A, Tanaka H, Maekita T, Ichinose M, Tatematsu M, Ushijima T (2010) Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res 70(4):1430-1440
-
(2010)
Cancer Res
, vol.70
, Issue.4
, pp. 1430-1440
-
-
Niwa, T.1
Tsukamoto, T.2
Toyoda, T.3
Mori, A.4
Tanaka, H.5
Maekita, T.6
Ichinose, M.7
Tatematsu, M.8
Ushijima, T.9
-
162
-
-
79958025266
-
An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling
-
21515785 3383860
-
Kominsky DJ, Keely S, MacManus CF, Glover LE, Scully M, Collins CB, Bowers BE, Campbell EL, Colgan SP (2011) An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. J Immunol 186(11):6505-6514
-
(2011)
J Immunol
, vol.186
, Issue.11
, pp. 6505-6514
-
-
Kominsky, D.J.1
Keely, S.2
MacManus, C.F.3
Glover, L.E.4
Scully, M.5
Collins, C.B.6
Bowers, B.E.7
Campbell, E.L.8
Colgan, S.P.9
-
163
-
-
78049285751
-
IFN induces miR-21 through a signal transducer and activator of transcription 3-dependent pathway as a suppressive negative feedback on IFN-induced apoptosis
-
20813833 3014825
-
Yang CH, Yue J, Fan M, Pfeffer LM (2010) IFN induces miR-21 through a signal transducer and activator of transcription 3-dependent pathway as a suppressive negative feedback on IFN-induced apoptosis. Cancer Res 70(20):8108-8116
-
(2010)
Cancer Res
, vol.70
, Issue.20
, pp. 8108-8116
-
-
Yang, C.H.1
Yue, J.2
Fan, M.3
Pfeffer, L.M.4
-
164
-
-
34548039517
-
Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
-
17496199
-
Loffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermuller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F (2007) Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110(4):1330-1333
-
(2007)
Blood
, vol.110
, Issue.4
, pp. 1330-1333
-
-
Loffler, D.1
Brocke-Heidrich, K.2
Pfeifer, G.3
Stocsits, C.4
Hackermuller, J.5
Kretzschmar, A.K.6
Burger, R.7
Gramatzki, M.8
Blumert, C.9
Bauer, K.10
Cvijic, H.11
Ullmann, A.K.12
Stadler, P.F.13
Horn, F.14
-
165
-
-
84865624014
-
Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells
-
22139078
-
Kong D, Piao YS, Yamashita S, Oshima H, Oguma K, Fushida S, Fujimura T, Minamoto T, Seno H, Yamada Y, Satou K, Ushijima T, Ishikawa TO, Oshima M (2012) Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. Oncogene 31(35):3949-3960
-
(2012)
Oncogene
, vol.31
, Issue.35
, pp. 3949-3960
-
-
Kong, D.1
Piao, Y.S.2
Yamashita, S.3
Oshima, H.4
Oguma, K.5
Fushida, S.6
Fujimura, T.7
Minamoto, T.8
Seno, H.9
Yamada, Y.10
Satou, K.11
Ushijima, T.12
Ishikawa, T.O.13
Oshima, M.14
-
166
-
-
84927578539
-
Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
-
25333344 4264448
-
Patel SA, Bhambra U, Charalambous MP, David RM, Edwards RJ, Lightfoot T, Boobis AR, Gooderham NJ (2014) Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3. Br J Cancer 111(12):2287-2296
-
(2014)
Br J Cancer
, vol.111
, Issue.12
, pp. 2287-2296
-
-
Patel, S.A.1
Bhambra, U.2
Charalambous, M.P.3
David, R.M.4
Edwards, R.J.5
Lightfoot, T.6
Boobis, A.R.7
Gooderham, N.J.8
-
167
-
-
78650108135
-
Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation
-
20848542 3006011
-
Olaru AV, Selaru FM, Mori Y, Vazquez C, David S, Paun B, Cheng Y, Jin Z, Yang J, Agarwal R, Abraham JM, Dassopoulos T, Harris M, Bayless TM, Kwon J, Harpaz N, Livak F, Meltzer SJ (2011) Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation. Inflamm Bowel Dis 17(1):221-231
-
(2011)
Inflamm Bowel Dis
, vol.17
, Issue.1
, pp. 221-231
-
-
Olaru, A.V.1
Selaru, F.M.2
Mori, Y.3
Vazquez, C.4
David, S.5
Paun, B.6
Cheng, Y.7
Jin, Z.8
Yang, J.9
Agarwal, R.10
Abraham, J.M.11
Dassopoulos, T.12
Harris, M.13
Bayless, T.M.14
Kwon, J.15
Harpaz, N.16
Livak, F.17
Meltzer, S.J.18
-
168
-
-
84866018690
-
TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma
-
22975373 3443566
-
Yang P, Li Q-J, Feng Y, Zhang Y, Markowitz GJ, Ning S, Deng Y, Zhao J, Jiang S, Yuan Y, Wang H-Y, Cheng S-Q, Xie D, Wang X-F (2012) TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. Cancer Cell 22(3):291-303
-
(2012)
Cancer Cell
, vol.22
, Issue.3
, pp. 291-303
-
-
Yang, P.1
Li, Q.-J.2
Feng, Y.3
Zhang, Y.4
Markowitz, G.J.5
Ning, S.6
Deng, Y.7
Zhao, J.8
Jiang, S.9
Yuan, Y.10
Wang, H.-Y.11
Cheng, S.-Q.12
Xie, D.13
Wang, X.-F.14
|