Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3

British Journal of Cancer

Volumn 111, Issue 12, 2014, Pages 2287-2296

  Patel, S A A ^a   Bhambra, U ^a   Charalambous, M P ^a   David, R M ^a   Edwards, R J ^a   Lightfoot, T ^b   Boobis, A R ^a   Gooderham, N J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

colorectal cancer; cytochrome P450; immunohistochemistry; inflammation; microRNA

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 2E1; INTERLEUKIN 6; MICRORNA; MICRORNA 27B; STAT3 PROTEIN; UNCLASSIFIED DRUG; CYP1B1 PROTEIN, HUMAN; MIRN27 MICRORNA, HUMAN; STAT3 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER RISK; CANCER STAGING; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; HCT116 CELL LINE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; GENETICS; METABOLISM;

AGED; CYTOCHROME P-450 CYP1B1; CYTOCHROME P-450 CYP2E1; DNA METHYLATION; FEMALE; GENE EXPRESSION; HCT116 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MALE; MICRORNAS; MIDDLE AGED; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84927578539     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.540     Document Type: Article

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