Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition

Oncogene

Volumn 32, Issue 45, 2013, Pages 5272-5282

  Guo, L ^a   Chen, C ^a   Shi, M ^a   Wang, F ^a   Chen, X ^b   Diao, D ^a   Hu, M ^a   Yu, M ^a   Qian, L ^a   Guo, N ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b HENAN UNIVERSITY   (China)

Author keywords

EMT; let 7; miR 200; OSM; Stat3

Indexed keywords

HIGH MOBILITY GROUP A PROTEIN; LIN 28 LET 7 HMGA2 PROTEIN; MICRORNA 200; MICRORNA 200 ZEB1 PROTEIN; MULTIPROTEIN COMPLEX; ONCOPROTEIN; ONCOSTATIN M; STAT3 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; EPIGENETIC REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; LINEAR ENERGY TRANSFER; LUNG METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; UPREGULATION; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HMGA2 PROTEIN; HOMEODOMAIN PROTEINS; HUMANS; INFLAMMATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUNG NEOPLASMS; MAMMARY NEOPLASMS, ANIMAL; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICRORNAS; NEOPLASM TRANSPLANTATION; ONCOSTATIN M; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84881303278     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.573     Document Type: Article

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