메뉴 건너뛰기




Volumn 13, Issue 8, 2015, Pages 1623-1632

ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ATM PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OLAPARIB; TELOMERASE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 84952874391     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.10.035     Document Type: Article
Times cited : (84)

References (67)
  • 2
    • 74049111326 scopus 로고    scopus 로고
    • Telomeres and telomerase in cancer
    • Artandi S.E., DePinho R.A. Telomeres and telomerase in cancer. Carcinogenesis 2010, 31:9-18.
    • (2010) Carcinogenesis , vol.31 , pp. 9-18
    • Artandi, S.E.1    DePinho, R.A.2
  • 3
    • 0029128539 scopus 로고
    • Boundary elements of the Tetrahymena telomerase RNA template and alignment domains
    • Autexier C., Greider C.W. Boundary elements of the Tetrahymena telomerase RNA template and alignment domains. Genes Dev. 1995, 9:2227-2239.
    • (1995) Genes Dev. , vol.9 , pp. 2227-2239
    • Autexier, C.1    Greider, C.W.2
  • 4
    • 3543130605 scopus 로고    scopus 로고
    • Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells
    • Baird D.M., Davis T., Rowson J., Jones C.J., Kipling D. Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells. Hum. Mol. Genet. 2004, 13:1515-1524.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 1515-1524
    • Baird, D.M.1    Davis, T.2    Rowson, J.3    Jones, C.J.4    Kipling, D.5
  • 5
  • 7
    • 33645532464 scopus 로고    scopus 로고
    • Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair
    • Bryant H.E., Helleday T. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair. Nucleic Acids Res. 2006, 34:1685-1691.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1685-1691
    • Bryant, H.E.1    Helleday, T.2
  • 8
    • 84864518203 scopus 로고    scopus 로고
    • Pacific biosciences sequencing technology for genotyping and variation discovery in human data
    • Carneiro M.O., Russ C., Ross M.G., Gabriel S.B., Nusbaum C., DePristo M.A. Pacific biosciences sequencing technology for genotyping and variation discovery in human data. BMC Genomics 2012, 13:375.
    • (2012) BMC Genomics , vol.13 , pp. 375
    • Carneiro, M.O.1    Russ, C.2    Ross, M.G.3    Gabriel, S.B.4    Nusbaum, C.5    DePristo, M.A.6
  • 9
    • 0035928740 scopus 로고    scopus 로고
    • Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
    • Chan S.W., Chang J., Prescott J., Blackburn E.H. Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr. Biol. 2001, 11:1240-1250.
    • (2001) Curr. Biol. , vol.11 , pp. 1240-1250
    • Chan, S.W.1    Chang, J.2    Prescott, J.3    Blackburn, E.H.4
  • 10
    • 0037439107 scopus 로고    scopus 로고
    • Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
    • Chen J.-L., Greider C.W. Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. EMBO J. 2003, 22:304-314.
    • (2003) EMBO J. , vol.22 , pp. 304-314
    • Chen, J.-L.1    Greider, C.W.2
  • 11
    • 0344011566 scopus 로고    scopus 로고
    • Template boundary definition in mammalian telomerase
    • Chen J.L., Greider C.W. Template boundary definition in mammalian telomerase. Genes Dev. 2003, 17:2747-2752.
    • (2003) Genes Dev. , vol.17 , pp. 2747-2752
    • Chen, J.L.1    Greider, C.W.2
  • 13
    • 0036132673 scopus 로고    scopus 로고
    • Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres
    • Cook B.D., Dynek J.N., Chang W., Shostak G., Smith S. Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol. Cell. Biol. 2002, 22:332-342.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 332-342
    • Cook, B.D.1    Dynek, J.N.2    Chang, W.3    Shostak, G.4    Smith, S.5
  • 14
    • 32544443342 scopus 로고    scopus 로고
    • Telomere length homeostasis requires that telomerase levels are limiting
    • Cristofari G., Lingner J. Telomere length homeostasis requires that telomerase levels are limiting. EMBO J. 2006, 25:565-574.
    • (2006) EMBO J. , vol.25 , pp. 565-574
    • Cristofari, G.1    Lingner, J.2
  • 15
    • 0035822641 scopus 로고    scopus 로고
    • Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
    • d'Adda di Fagagna F., Hande M.P., Tong W.M., Roth D., Lansdorp P.M., Wang Z.Q., Jackson S.P. Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr. Biol. 2001, 11:1192-1196.
    • (2001) Curr. Biol. , vol.11 , pp. 1192-1196
    • d'Adda di Fagagna, F.1    Hande, M.P.2    Tong, W.M.3    Roth, D.4    Lansdorp, P.M.5    Wang, Z.Q.6    Jackson, S.P.7
  • 18
    • 71149093724 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange T. How telomeres solve the end-protection problem. Science 2009, 326:948-952.
    • (2009) Science , vol.326 , pp. 948-952
    • de Lange, T.1
  • 19
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
    • Diede S.J., Gottschling D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 1999, 99:723-733.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 20
  • 21
    • 33144482714 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
    • Feldser D., Strong M.A., Greider C.W. Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres. Proc. Natl. Acad. Sci. USA 2006, 103:2249-2251.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2249-2251
    • Feldser, D.1    Strong, M.A.2    Greider, C.W.3
  • 23
    • 33750431337 scopus 로고    scopus 로고
    • Regulation of telomere elongation by the cyclin-dependent kinase CDK1
    • Frank C.J., Hyde M., Greider C.W. Regulation of telomere elongation by the cyclin-dependent kinase CDK1. Mol. Cell 2006, 24:423-432.
    • (2006) Mol. Cell , vol.24 , pp. 423-432
    • Frank, C.J.1    Hyde, M.2    Greider, C.W.3
  • 24
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
    • Greenwell P.W., Kronmal S.L., Porter S.E., Gassenhuber J., Obermaier B., Petes T.D. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 1995, 82:823-829.
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 25
    • 0025914141 scopus 로고
    • Telomerase is processive
    • Greider C.W. Telomerase is processive. Mol. Cell. Biol. 1991, 11:4572-4580.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4572-4580
    • Greider, C.W.1
  • 26
    • 0033028428 scopus 로고    scopus 로고
    • Telomerase activation. One step on the road to cancer?
    • Greider C.W. Telomerase activation. One step on the road to cancer?. Trends Genet. 1999, 15:109-112.
    • (1999) Trends Genet. , vol.15 , pp. 109-112
    • Greider, C.W.1
  • 27
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider C.W., Blackburn E.H. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985, 43:405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 28
    • 0035282711 scopus 로고    scopus 로고
    • Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia
    • Hande M.P., Balajee A.S., Tchirkov A., Wynshaw-Boris A., Lansdorp P.M. Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum. Mol. Genet. 2001, 10:519-528.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 519-528
    • Hande, M.P.1    Balajee, A.S.2    Tchirkov, A.3    Wynshaw-Boris, A.4    Lansdorp, P.M.5
  • 29
    • 28944455294 scopus 로고    scopus 로고
    • Short telomeres, even in the presence of telomerase, limit tissue renewal capacity
    • Hao L.Y., Armanios M., Strong M.A., Karim B., Feldser D.M., Huso D., Greider C.W. Short telomeres, even in the presence of telomerase, limit tissue renewal capacity. Cell 2005, 123:1121-1131.
    • (2005) Cell , vol.123 , pp. 1121-1131
    • Hao, L.Y.1    Armanios, M.2    Strong, M.A.3    Karim, B.4    Feldser, D.M.5    Huso, D.6    Greider, C.W.7
  • 30
    • 0025743438 scopus 로고
    • Telomerase primer specificity and chromosome healing
    • Harrington L.A., Greider C.W. Telomerase primer specificity and chromosome healing. Nature 1991, 353:451-454.
    • (1991) Nature , vol.353 , pp. 451-454
    • Harrington, L.A.1    Greider, C.W.2
  • 32
    • 33644774924 scopus 로고    scopus 로고
    • Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping
    • Hsiao S.J., Poitras M.F., Cook B.D., Liu Y., Smith S. Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping. Mol. Cell. Biol. 2006, 26:2044-2054.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2044-2054
    • Hsiao, S.J.1    Poitras, M.F.2    Cook, B.D.3    Liu, Y.4    Smith, S.5
  • 33
    • 0033532056 scopus 로고    scopus 로고
    • Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
    • Kang S.S., Kwon T., Kwon D.Y., Do S.I. Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J. Biol. Chem. 1999, 274:13085-13090.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13085-13090
    • Kang, S.S.1    Kwon, T.2    Kwon, D.Y.3    Do, S.I.4
  • 34
    • 0033605145 scopus 로고    scopus 로고
    • P53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J., Broccoli D., Dai Y., Hardy S., de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science 1999, 283:1321-1325.
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    de Lange, T.5
  • 35
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan M.B., Lim D.S. The many substrates and functions of ATM. Nat. Rev. Mol. Cell Biol. 2000, 1:179-186.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 36
    • 84945570905 scopus 로고    scopus 로고
    • FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy
    • Kim G., Ison G., McKee A.E., Zhang H., Tang S., Gwise T., Sridhara R., Lee E., Tzou A., Philip R., et al. FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy. Clin. Cancer Res. 2015, 21:4257-4261.
    • (2015) Clin. Cancer Res. , vol.21 , pp. 4257-4261
    • Kim, G.1    Ison, G.2    McKee, A.E.3    Zhang, H.4    Tang, S.5    Gwise, T.6    Sridhara, R.7    Lee, E.8    Tzou, A.9    Philip, R.10
  • 37
    • 0027140403 scopus 로고
    • New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats
    • Kramer K.M., Haber J.E. New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev. 1993, 7(12A):2345-2356.
    • (1993) Genes Dev. , vol.7 , Issue.12 , pp. 2345-2356
    • Kramer, K.M.1    Haber, J.E.2
  • 40
    • 70249120364 scopus 로고    scopus 로고
    • Kinase-independent functions of TEL1 in telomere maintenance
    • Ma Y., Greider C.W. Kinase-independent functions of TEL1 in telomere maintenance. Mol. Cell. Biol. 2009, 29:5193-5202.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5193-5202
    • Ma, Y.1    Greider, C.W.2
  • 42
    • 0025808098 scopus 로고
    • Recognition of a chromosome truncation site associated with alpha-thalassaemia by human telomerase
    • Morin G.B. Recognition of a chromosome truncation site associated with alpha-thalassaemia by human telomerase. Nature 1991, 353:454-456.
    • (1991) Nature , vol.353 , pp. 454-456
    • Morin, G.B.1
  • 43
    • 59249101446 scopus 로고    scopus 로고
    • Short telomeres initiate telomere recombination in primary and tumor cells
    • Morrish T.A., Greider C.W. Short telomeres initiate telomere recombination in primary and tumor cells. PLoS Genet. 2009, 5:e1000357.
    • (2009) PLoS Genet. , vol.5 , pp. e1000357
    • Morrish, T.A.1    Greider, C.W.2
  • 44
    • 82955233574 scopus 로고    scopus 로고
    • Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast
    • Moser B.A., Chang Y.T., Kosti J., Nakamura T.M. Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast. Nat. Struct. Mol. Biol. 2011, 18:1408-1413.
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 1408-1413
    • Moser, B.A.1    Chang, Y.T.2    Kosti, J.3    Nakamura, T.M.4
  • 45
    • 0031686574 scopus 로고    scopus 로고
    • Circular chromosome formation in a fission yeast mutant defective in two ATM homologues
    • Naito T., Matsuura A., Ishikawa F. Circular chromosome formation in a fission yeast mutant defective in two ATM homologues. Nat. Genet. 1998, 20:203-206.
    • (1998) Nat. Genet. , vol.20 , pp. 203-206
    • Naito, T.1    Matsuura, A.2    Ishikawa, F.3
  • 46
    • 0036670615 scopus 로고    scopus 로고
    • Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres
    • Nakamura T.M., Moser B.A., Russell P. Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics 2002, 161:1437-1452.
    • (2002) Genetics , vol.161 , pp. 1437-1452
    • Nakamura, T.M.1    Moser, B.A.2    Russell, P.3
  • 47
    • 84870980867 scopus 로고    scopus 로고
    • The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
    • Nandakumar J., Bell C.F., Weidenfeld I., Zaug A.J., Leinwand L.A., Cech T.R. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature 2012, 492:285-289.
    • (2012) Nature , vol.492 , pp. 285-289
    • Nandakumar, J.1    Bell, C.F.2    Weidenfeld, I.3    Zaug, A.J.4    Leinwand, L.A.5    Cech, T.R.6
  • 48
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm W., de Lange T. How shelterin protects mammalian telomeres. Annu. Rev. Genet. 2008, 42:301-334.
    • (2008) Annu. Rev. Genet. , vol.42 , pp. 301-334
    • Palm, W.1    de Lange, T.2
  • 49
    • 84924384551 scopus 로고    scopus 로고
    • Mechanisms of ATM Activation
    • Paull T.T. Mechanisms of ATM Activation. Annu. Rev. Biochem. 2015, 84:711-738.
    • (2015) Annu. Rev. Biochem. , vol.84 , pp. 711-738
    • Paull, T.T.1
  • 51
    • 0032793298 scopus 로고    scopus 로고
    • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
    • Ritchie K.B., Mallory J.C., Petes T.D. Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 1999, 19:6065-6075.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6065-6075
    • Ritchie, K.B.1    Mallory, J.C.2    Petes, T.D.3
  • 53
    • 0037134452 scopus 로고    scopus 로고
    • The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)
    • Seimiya H., Smith S. The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). J. Biol. Chem. 2002, 277:14116-14126.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14116-14126
    • Seimiya, H.1    Smith, S.2
  • 54
    • 84875423827 scopus 로고    scopus 로고
    • The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    • Shiloh Y., Ziv Y. The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat. Rev. Mol. Cell Biol. 2013, 14:197-210.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 197-210
    • Shiloh, Y.1    Ziv, Y.2
  • 55
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • Smogorzewska A., de Lange T. Different telomere damage signaling pathways in human and mouse cells. EMBO J. 2002, 21:4338-4348.
    • (2002) EMBO J. , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    de Lange, T.2
  • 56
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska A., de Lange T. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 2004, 73:177-208.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 177-208
    • Smogorzewska, A.1    de Lange, T.2
  • 57
    • 0031556539 scopus 로고    scopus 로고
    • Normal telomere maintenance in immortal ataxia telangiectasia cell lines
    • Sprung C.N., Bryan T.M., Reddel R.R., Murnane J.P. Normal telomere maintenance in immortal ataxia telangiectasia cell lines. Mutat. Res. 1997, 379:177-184.
    • (1997) Mutat. Res. , vol.379 , pp. 177-184
    • Sprung, C.N.1    Bryan, T.M.2    Reddel, R.R.3    Murnane, J.P.4
  • 58
    • 0037320653 scopus 로고    scopus 로고
    • Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia
    • Tchirkov A., Lansdorp P.M. Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia. Hum. Mol. Genet. 2003, 12:227-232.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 227-232
    • Tchirkov, A.1    Lansdorp, P.M.2
  • 59
    • 84952877130 scopus 로고    scopus 로고
    • ATM and ATR signaling regulate the recruitment of human telomerase to telomeres
    • Published online November 12, 2015
    • Tong A.S., Stern J.L., Sfeir A., Kartawinata M., de Lange T., Zhu X.D., Bryan T.M. ATM and ATR signaling regulate the recruitment of human telomerase to telomeres. Cell Rep. 2015, 13. Published online November 12, 2015. 10.1016/j.celrep.2015.10.041.
    • (2015) Cell Rep. , vol.13
    • Tong, A.S.1    Stern, J.L.2    Sfeir, A.3    Kartawinata, M.4    de Lange, T.5    Zhu, X.D.6    Bryan, T.M.7
  • 60
    • 79251564088 scopus 로고    scopus 로고
    • A review of PARP inhibitors: from bench to bedside
    • Underhill C., Toulmonde M., Bonnefoi H. A review of PARP inhibitors: from bench to bedside. Ann. Oncol. 2011, 22:268-279.
    • (2011) Ann. Oncol. , vol.22 , pp. 268-279
    • Underhill, C.1    Toulmonde, M.2    Bonnefoi, H.3
  • 61
    • 0030761351 scopus 로고    scopus 로고
    • ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
    • Vaziri H., West M.D., Allsopp R.C., Davison T.S., Wu Y.S., Arrowsmith C.H., Poirier G.G., Benchimol S. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 1997, 16:6018-6033.
    • (1997) EMBO J. , vol.16 , pp. 6018-6033
    • Vaziri, H.1    West, M.D.2    Allsopp, R.C.3    Davison, T.S.4    Wu, Y.S.5    Arrowsmith, C.H.6    Poirier, G.G.7    Benchimol, S.8
  • 63
    • 33846691378 scopus 로고    scopus 로고
    • The POT1-TPP1 telomere complex is a telomerase processivity factor
    • Wang F., Podell E.R., Zaug A.J., Yang Y., Baciu P., Cech T.R., Lei M. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 2007, 445:506-510.
    • (2007) Nature , vol.445 , pp. 506-510
    • Wang, F.1    Podell, E.R.2    Zaug, A.J.3    Yang, Y.4    Baciu, P.5    Cech, T.R.6    Lei, M.7
  • 64
    • 34548492016 scopus 로고    scopus 로고
    • MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
    • Wu Y., Xiao S., Zhu X.D. MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Nat. Struct. Mol. Biol. 2007, 14:832-840.
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 832-840
    • Wu, Y.1    Xiao, S.2    Zhu, X.D.3
  • 65
    • 0030565541 scopus 로고    scopus 로고
    • Reduced telomere length in ataxia-telangiectasia fibroblasts
    • Xia S.J., Shammas M.A., Shmookler Reis R.J. Reduced telomere length in ataxia-telangiectasia fibroblasts. Mutat. Res. 1996, 364:1-11.
    • (1996) Mutat. Res. , vol.364 , pp. 1-11
    • Xia, S.J.1    Shammas, M.A.2    Shmookler Reis, R.J.3
  • 67
    • 84856655950 scopus 로고    scopus 로고
    • Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast
    • Yamazaki H., Tarumoto Y., Ishikawa F. Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast. Genes Dev. 2012, 26:241-246.
    • (2012) Genes Dev. , vol.26 , pp. 241-246
    • Yamazaki, H.1    Tarumoto, Y.2    Ishikawa, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.