Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1

OncoTargets and Therapy

Volumn 8, Issue , 2015, Pages 3649-3664

  Dong, Liwei ^a   Wang, Hongge ^a   Niu, Jiajing ^a   Zou, Mingwei ^b   Wu, Nuoting ^a   Yu, Debin ^a   Wang, Ye ^a   Zou, Zhihua ^a  

^a JILIN UNIVERSITY   (China)

^b UNIVERSITY OF HOUSTON   (United States)

Author keywords

8 oxoG; Apoptosis; Cell cycle arrest; DNA damage; Echinacoside; MTH1

Indexed keywords

8 HYDROXYGUANINE; CRIZOTINIB; CYCLIN DEPENDENT KINASE INHIBITOR 1; ECHINACOSIDE; GLYCYRRHETINIC; HYPERIN; JATRORRHIZINE; KAEMPFEROL; MAGNOLOL; MTH1 PROTEIN; NUDIX HYDROLASE; PIPERINE; PLANT MEDICINAL PRODUCT; QUERCETIN; REACTIVE OXYGEN METABOLITE; RUTOSIDE; SAFFLOMIN A; SALIDROSIDE; SCUTELLARIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL LINE; CELL CYCLE ARREST; CISTANCHE; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DNA DAMAGE; DNA MARKER; DRUG DETERMINATION; DRUG SCREENING; DRUG STRUCTURE; ECHINACEA; EMBRYO; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME MECHANISM; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MCF 7 CELL LINE; MOUSE; NONHUMAN; OSTEOSARCOMA CELL LINE;

EID: 84949684866     PISSN: 11786930     EISSN: 11786930     Source Type: Journal    
DOI: 10.2147/OTT.S94513     Document Type: Article

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