-
2
-
-
33845690880
-
Ribonucleotide reductase and the regulation of DNA replication: An old story and an ancient heritage
-
Herrick J, Sclavi B. Ribonucleotide reductase and the regulation of DNA replication: an old story and an ancient heritage. Mol Microbiol 2007;63:22-34.
-
(2007)
Mol Microbiol
, vol.63
, pp. 22-34
-
-
Herrick, J.1
Sclavi, B.2
-
3
-
-
33846418710
-
Ribonucleotide reductase small subunit p53R2 facilitates p21 induction of G1 arrest under UV irradiation
-
Xue L, Zhou B, Liu X, Heung Y, Chau J, Chu E, et al. Ribonucleotide reductase small subunit p53R2 facilitates p21 induction of G1 arrest under UV irradiation. Cancer Res 2007;67:16-21.
-
(2007)
Cancer Res
, vol.67
, pp. 16-21
-
-
Xue, L.1
Zhou, B.2
Liu, X.3
Heung, Y.4
Chau, J.5
Chu, E.6
-
5
-
-
79952331478
-
Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization
-
Fairman JW, Wijerathna SR, Ahmad MF, Xu H, Nakano R, Jha S, et al. Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat Struct Mol Biol 2011;18:316-22.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 316-322
-
-
Fairman, J.W.1
Wijerathna, S.R.2
Ahmad, M.F.3
Xu, H.4
Nakano, R.5
Jha, S.6
-
6
-
-
33748785426
-
Enzymatically active mammalian ribonucleotide reductase exists primarily as an alpha6beta2 octamer
-
Rofougaran R, Vodnala M, Hofer A. Enzymatically active mammalian ribonucleotide reductase exists primarily as an alpha6beta2 octamer. J Biol Chem 2006;281:27705-11.
-
(2006)
J Biol Chem
, vol.281
, pp. 27705-27711
-
-
Rofougaran, R.1
Vodnala, M.2
Hofer, A.3
-
7
-
-
0022260274
-
Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits
-
Engstrom Y, Eriksson S, Jildevik I, Skog S, Thelander L, Tribukait B. Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits. J Biol Chem 1985; 260:9114-6.
-
(1985)
J Biol Chem
, vol.260
, pp. 9114-9116
-
-
Engstrom, Y.1
Eriksson, S.2
Jildevik, I.3
Skog, S.4
Thelander, L.5
Tribukait, B.6
-
8
-
-
33846891365
-
Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress
-
Lin ZP, Belcourt MF, Carbone R, Eaton JS, Penketh PG, Shadel GS, et al. Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress. Biochem Pharmacol 2007;73:760-72.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 760-772
-
-
Lin, Z.P.1
Belcourt, M.F.2
Carbone, R.3
Eaton, J.S.4
Penketh, P.G.5
Shadel, G.S.6
-
9
-
-
33745823841
-
Ribonucleotide reductase inhibitors and future drug design
-
Shao J, Zhou B, Chu B, Yen Y. Ribonucleotide reductase inhibitors and future drug design. Curr Cancer Drug Targets 2006;6:409-31.
-
(2006)
Curr Cancer Drug Targets
, vol.6
, pp. 409-431
-
-
Shao, J.1
Zhou, B.2
Chu, B.3
Yen, Y.4
-
10
-
-
38049090214
-
DNA replication stress, genome instability and aging
-
Burhans WC, Weinberger M. DNA replication stress, genome instability and aging. Nucleic Acids Res 2007;35:7545-56.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7545-7556
-
-
Burhans, W.C.1
Weinberger, M.2
-
11
-
-
0347089015
-
Mono- and multisite phosphorylation enhances Bcl2′s antiapoptotic function and inhibition of cell cycle entry functions
-
Deng X, Gao F, Flagg T, May WS Jr. Mono- and multisite phosphorylation enhances Bcl2′s antiapoptotic function and inhibition of cell cycle entry functions. Proc Natl Acad Sci U S A 2004;101:153-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 153-158
-
-
Deng, X.1
Gao, F.2
Flagg, T.3
May Jr., W.S.4
-
12
-
-
39549112507
-
Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway
-
Wang Q, Gao F, May WS, Zhang Y, Flagg T, Deng X. Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway. Mol Cell 2008;29:488-98.
-
(2008)
Mol Cell
, vol.29
, pp. 488-498
-
-
Wang, Q.1
Gao, F.2
May, W.S.3
Zhang, Y.4
Flagg, T.5
Deng, X.6
-
14
-
-
0022379447
-
The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
-
Tsujimoto Y, Gorham J, Cossman J, Jaffe E, Croce CM. The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 1985;229:1390-3.
-
(1985)
Science
, vol.229
, pp. 1390-1393
-
-
Tsujimoto, Y.1
Gorham, J.2
Cossman, J.3
Jaffe, E.4
Croce, C.M.5
-
16
-
-
0142152451
-
Bcl2 retards G1/S cell cycle transition by regulating intracellular ROS
-
Deng X, Gao F, May WS Jr. Bcl2 retards G1/S cell cycle transition by regulating intracellular ROS. Blood 2003;102:3179-85.
-
(2003)
Blood
, vol.102
, pp. 3179-3185
-
-
Deng, X.1
Gao, F.2
May Jr., W.S.3
-
17
-
-
79955799175
-
Doublestrand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
-
Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M. Doublestrand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 2011;145:529-42.
-
(2011)
Cell
, vol.145
, pp. 529-542
-
-
Schlacher, K.1
Christ, N.2
Siaud, N.3
Egashira, A.4
Wu, H.5
Jasin, M.6
-
18
-
-
0032559794
-
Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
-
Jackson DA, Pombo A. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J Cell Biol 1998;140:1285-95.
-
(1998)
J Cell Biol
, vol.140
, pp. 1285-1295
-
-
Jackson, D.A.1
Pombo, A.2
-
19
-
-
0038298811
-
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes
-
Henry-Mowatt J, Jackson D, Masson JY, Johnson PA, Clements PM, Benson FE, et al. XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Mol Cell 2003;11: 1109-17.
-
(2003)
Mol Cell
, vol.11
, pp. 1109-1117
-
-
Henry-Mowatt, J.1
Jackson, D.2
Masson, J.Y.3
Johnson, P.A.4
Clements, P.M.5
Benson, F.E.6
-
20
-
-
0036791653
-
Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus
-
Pasero P, Bensimon A, Schwob E. Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus. Genes Dev 2002;16:2479-84.
-
(2002)
Genes Dev
, vol.16
, pp. 2479-2484
-
-
Pasero, P.1
Bensimon, A.2
Schwob, E.3
-
21
-
-
0026801917
-
Quantitation of deoxyribonucleoside 50-triphosphates by a sequential boronate and anion-exchange high-pressure liquid chromatographic procedure
-
Shewach DS. Quantitation of deoxyribonucleoside 50-triphosphates by a sequential boronate and anion-exchange high-pressure liquid chromatographic procedure. Anal Biochem 1992;206:178-82.
-
(1992)
Anal Biochem
, vol.206
, pp. 178-182
-
-
Shewach, D.S.1
-
22
-
-
79955525482
-
Nucleotide deficiency promotes genomic instability in early stages of cancer development
-
Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, et al. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell 2011;145:435-46.
-
(2011)
Cell
, vol.145
, pp. 435-446
-
-
Bester, A.C.1
Roniger, M.2
Oren, Y.S.3
Im, M.M.4
Sarni, D.5
Chaoat, M.6
-
23
-
-
34250721675
-
Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: A new paradigm for antimetabolite radiosensitizers
-
Flanagan SA, Robinson BW, Krokosky CM, Shewach DS. Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: a new paradigm for antimetabolite radiosensitizers. Mol Cancer Ther 2007;6:1858-68.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1858-1868
-
-
Flanagan, S.A.1
Robinson, B.W.2
Krokosky, C.M.3
Shewach, D.S.4
-
24
-
-
0142250911
-
The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53
-
Zhou B, Liu X, Mo X, Xue L, Darwish D, Qiu W, et al. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53. Cancer Res 2003;63:6583-94.
-
(2003)
Cancer Res
, vol.63
, pp. 6583-6594
-
-
Zhou, B.1
Liu, X.2
Mo, X.3
Xue, L.4
Darwish, D.5
Qiu, W.6
-
25
-
-
70449522304
-
Topoisomerase i suppresses genomic instability by preventing interference between replication and transcription
-
Tuduri S, Crabbe L, Conti C, Tourriere H, Holtgreve-Grez H, Jauch A, et al. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol 2009;11:1315-24.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1315-1324
-
-
Tuduri, S.1
Crabbe, L.2
Conti, C.3
Tourriere, H.4
Holtgreve-Grez, H.5
Jauch, A.6
-
26
-
-
70449725150
-
Staphylococcus aureus synthesizes adenosine to escape host immune responses
-
Thammavongsa V, Kern JW, Missiakas DM, Schneewind O. Staphylococcus aureus synthesizes adenosine to escape host immune responses. J Exp Med 2009;206:2417-27.
-
(2009)
J Exp Med
, vol.206
, pp. 2417-2427
-
-
Thammavongsa, V.1
Kern, J.W.2
Missiakas, D.M.3
Schneewind, O.4
-
27
-
-
58849086028
-
BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells
-
Huang S, Okumura K, Sinicrope FA. BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells. Clin Cancer Res 2009;15:150-9.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 150-159
-
-
Huang, S.1
Okumura, K.2
Sinicrope, F.A.3
-
28
-
-
0037186146
-
Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration
-
Vail ME, Chaisson ML, Thompson J, Fausto N. Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration. Oncogene 2002;21:1548-55.
-
(2002)
Oncogene
, vol.21
, pp. 1548-1555
-
-
Vail, M.E.1
Chaisson, M.L.2
Thompson, J.3
Fausto, N.4
-
29
-
-
84857060479
-
DNTP pools determine fork progression and origin usage under replication stress
-
Poli J, Tsaponina O, Crabbe L, Keszthelyi A, Pantesco V, Chabes A, et al. dNTP pools determine fork progression and origin usage under replication stress. EMBO J 2012;31:883-94.
-
(2012)
EMBO J
, vol.31
, pp. 883-894
-
-
Poli, J.1
Tsaponina, O.2
Crabbe, L.3
Keszthelyi, A.4
Pantesco, V.5
Chabes, A.6
-
30
-
-
84861544402
-
Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair
-
D'Angiolella V, Donato V, Forrester FM, Jeong YT, Pellacani C, Kudo Y, et al. Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell 2012;149: 1023-34.
-
(2012)
Cell
, vol.149
, pp. 1023-1034
-
-
D'Angiolella, V.1
Donato, V.2
Forrester, F.M.3
Jeong, Y.T.4
Pellacani, C.5
Kudo, Y.6
-
31
-
-
34547814092
-
Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells
-
Conti C, Sacca B, Herrick J, Lalou C, Pommier Y, Bensimon A. Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells. Mol Biol Cell 2007;18:3059-67.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 3059-3067
-
-
Conti, C.1
Sacca, B.2
Herrick, J.3
Lalou, C.4
Pommier, Y.5
Bensimon, A.6
-
32
-
-
52949092763
-
Replication fork movement sets chromatin loop size and origin choice in mammalian cells
-
Courbet S, Gay S, Arnoult N, Wronka G, Anglana M, Brison O, et al. Replication fork movement sets chromatin loop size and origin choice in mammalian cells. Nature 2008;455:557-60.
-
(2008)
Nature
, vol.455
, pp. 557-560
-
-
Courbet, S.1
Gay, S.2
Arnoult, N.3
Wronka, G.4
Anglana, M.5
Brison, O.6
-
33
-
-
0032146987
-
Bcl-2-family proteins: The role of the BH3 domain in apoptosis
-
Kelekar A, Thompson CB. Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol 1998;8:324-30.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
34
-
-
0034594978
-
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
-
Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, et al. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature 2000;404: 42-9.
-
(2000)
Nature
, vol.404
, pp. 42-49
-
-
Tanaka, H.1
Arakawa, H.2
Yamaguchi, T.3
Shiraishi, K.4
Fukuda, S.5
Matsui, K.6
-
35
-
-
84865181704
-
Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells
-
Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V. Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells. Proc Natl Acad Sci U S A 2012;109:13302-7.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13302-13307
-
-
Pontarin, G.1
Ferraro, P.2
Bee, L.3
Reichard, P.4
Bianchi, V.5
-
36
-
-
34249811206
-
Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion
-
Bourdon A, Minai L, Serre V, Jais JP, Sarzi E, Aubert S, et al. Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nat Genet 2007;39: 776-80.
-
(2007)
Nat Genet
, vol.39
, pp. 776-780
-
-
Bourdon, A.1
Minai, L.2
Serre, V.3
Jais, J.P.4
Sarzi, E.5
Aubert, S.6
-
37
-
-
4344618200
-
A mechanism for the proapoptotic activity of ursodeoxycholic acid: Effects on Bcl-2 conformation
-
Castelli M, Reiners JJ, Kessel D. A mechanism for the proapoptotic activity of ursodeoxycholic acid: effects on Bcl-2 conformation. Cell Death Differ 2004;11:906-14.
-
(2004)
Cell Death Differ
, vol.11
, pp. 906-914
-
-
Castelli, M.1
Reiners, J.J.2
Kessel, D.3
-
38
-
-
0031465443
-
Conversion of Bcl-2 to a Bax-like death effector by caspases
-
Cheng EH, Kirsch DG, Clem RJ, Ravi R, Kastan MB, Bedi A, et al. Conversion of Bcl-2 to a Bax-like death effector by caspases. Science 1997;278:1966-8.
-
(1997)
Science
, vol.278
, pp. 1966-1968
-
-
Cheng, E.H.1
Kirsch, D.G.2
Clem, R.J.3
Ravi, R.4
Kastan, M.B.5
Bedi, A.6
-
39
-
-
0026582672
-
Ribonucleotide reductase: Regulation, regulation, regulation
-
Elledge SJ, Zhou Z, Allen JB. Ribonucleotide reductase: regulation, regulation, regulation. Trends Biochem Sci 1992;17:119-23.
-
(1992)
Trends Biochem Sci
, vol.17
, pp. 119-123
-
-
Elledge, S.J.1
Zhou, Z.2
Allen, J.B.3
-
40
-
-
33746539166
-
DNA precursor metabolism and genomic stability
-
Mathews CK. DNA precursor metabolism and genomic stability. FASEB J 2006;20:1300-14.
-
(2006)
FASEB J
, vol.20
, pp. 1300-1314
-
-
Mathews, C.K.1
-
41
-
-
84871554234
-
DNTP supply gene expression patterns after P53 loss
-
Radivoyevitch T, Saunthararajah Y, Pink J, Ferris G, Lent I, Jackson M, et al. dNTP supply gene expression patterns after P53 loss. Cancers 2012;4:1212-24.
-
(2012)
Cancers
, vol.4
, pp. 1212-1224
-
-
Radivoyevitch, T.1
Saunthararajah, Y.2
Pink, J.3
Ferris, G.4
Lent, I.5
Jackson, M.6
-
42
-
-
56649111359
-
Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage
-
Pontarin G, Fijolek A, Pizzo P, Ferraro P, Rampazzo C, Pozzan T, et al. Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage. Proc Natl Acad Sci U S A 2008; 105:17801-6.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17801-17806
-
-
Pontarin, G.1
Fijolek, A.2
Pizzo, P.3
Ferraro, P.4
Rampazzo, C.5
Pozzan, T.6
-
43
-
-
9044225527
-
BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy
-
Reed JC, Miyashita T, Takayama S, Wang HG, Sato T, Krajewski S, et al. BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy. J Cell Biochem 1996;60:23-32.
-
(1996)
J Cell Biochem
, vol.60
, pp. 23-32
-
-
Reed, J.C.1
Miyashita, T.2
Takayama, S.3
Wang, H.G.4
Sato, T.5
Krajewski, S.6
-
44
-
-
78449268395
-
Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells
-
Niida H, Shimada M, Murakami H, Nakanishi M. Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells. Cancer Sci 2010;101:2505-9.
-
(2010)
Cancer Sci
, vol.101
, pp. 2505-2509
-
-
Niida, H.1
Shimada, M.2
Murakami, H.3
Nakanishi, M.4
-
45
-
-
42349085603
-
Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms
-
Xu X, Page JL, Surtees JA, Liu H, Lagedrost S, Lu Y, et al. Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms. Cancer Res 2008;68:2652-60.
-
(2008)
Cancer Res
, vol.68
, pp. 2652-2660
-
-
Xu, X.1
Page, J.L.2
Surtees, J.A.3
Liu, H.4
Lagedrost, S.5
Lu, Y.6
-
46
-
-
0032878342
-
Quantitative analysis detects ubiquitous expression of apoptotic regulators in B cell non-Hodgkin's lymphomas
-
Xerri L, Devilard E, Bouabdallah R, Hassoun J, Chaperot L, Birg F, et al. Quantitative analysis detects ubiquitous expression of apoptotic regulators in B cell non-Hodgkin's lymphomas. Leukemia 1999;13:1548-53.
-
(1999)
Leukemia
, vol.13
, pp. 1548-1553
-
-
Xerri, L.1
Devilard, E.2
Bouabdallah, R.3
Hassoun, J.4
Chaperot, L.5
Birg, F.6
-
48
-
-
0036681293
-
Overexpression of Bcl-2 in squamous cell carcinoma of the larynx: A marker of radioresistance
-
Condon LT, Ashman JN, Ell SR, Stafford ND, Greenman J, Cawkwell L. Overexpression of Bcl-2 in squamous cell carcinoma of the larynx: a marker of radioresistance. Int J Cancer 2002;100: 472-5.
-
(2002)
Int J Cancer
, vol.100
, pp. 472-475
-
-
Condon, L.T.1
Ashman, J.N.2
Ell, S.R.3
Stafford, N.D.4
Greenman, J.5
Cawkwell, L.6
-
49
-
-
15644374180
-
Immunohistochemical detection of bcl2, p53, mdm2 and p21/waf1 proteins in small-cell lung carcinomas
-
Stefanaki K, Rontogiannis D, Vamvouka C, Bolioti S, Chaniotis V, Sotsiou F, et al. Immunohistochemical detection of bcl2, p53, mdm2 and p21/waf1 proteins in small-cell lung carcinomas. Anticancer Res 1998;18:1689-95.
-
(1998)
Anticancer Res
, vol.18
, pp. 1689-1695
-
-
Stefanaki, K.1
Rontogiannis, D.2
Vamvouka, C.3
Bolioti, S.4
Chaniotis, V.5
Sotsiou, F.6
-
50
-
-
84879876675
-
RRM2 regulates Bcl-2 in head and neck and lung cancers: A potential target for cancer therapy
-
Rahman MA, Amin AR, Wang D, Koenig L, Nannapaneni S, Chen Z, et al. RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy. Clin Cancer Res 2013;19: 3416-28.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3416-3428
-
-
Rahman, M.A.1
Amin, A.R.2
Wang, D.3
Koenig, L.4
Nannapaneni, S.5
Chen, Z.6
|