Addiction to MTH1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry

DNA Repair

Volumn 33, Issue , 2015, Pages 101-110

  Coskun, Erdem ^a,b   Jaruga, Pawel ^a   Jemth, Ann Sofie ^c   Loseva, Olga ^c   Scanlan, Leona D ^a   Tona, Alessandro ^a   Lowenthal, Mark S ^a   Helleday, Thomas ^c   Dizdaroglu, Miral ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b GAZI UNIVERSITY   (Turkey)

^c SCIENCE FOR LIFE LABORATORY   (Sweden)

Author keywords

Extreme expression; Isotope dilution mass spectrometry; MTH1 protein; Nucleotide pool; Stable isotope labeled MTH1

Indexed keywords

MTH1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; 8-OXODGTPASE; DNA LIGASE; NITROGEN; PEPTIDE; PHOSPHATASE; TRYPSIN;

ABSORPTION SPECTROPHOTOMETRY; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER TISSUE; FEMALE; HELA CELL LINE; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MCF 7 CELL LINE; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL NOISE RATIO; STANDARD; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; BREAST TUMOR; CHEMISTRY; HYDROLYSIS; METABOLISM; MOLECULAR GENETICS; PROCEDURES; TUMOR CELL LINE;

AMINO ACID SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DNA REPAIR ENZYMES; FEMALE; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; NITROGEN ISOTOPES; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; TANDEM MASS SPECTROMETRY; TRYPSIN;

EID: 84937196705     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2015.05.008     Document Type: Article

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