Amino acid-induced activation of mTORC1 in rat liver is attenuated by short-term consumption of a high-fat diet

Journal of Nutrition

Volumn 145, Issue 11, 2015, Pages 2496-2502

  Kimball, Scot R ^a   Ravi, Suhana ^a   Gordon, Bradley S ^a   Dennis, Michael D ^a   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

High fat diet; Liver; mTORC1; Obesity; Signaling

Indexed keywords

AMINO ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE B; PROTEIN RAGA; PROTEIN RAGC; PROTEIN SESTRIN 1; PROTEIN SESTRIN 2; PROTEIN SESTRIN 3; REPRESSOR PROTEIN; S6 KINASE; S6 KINASE 1; TUBERIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; GLUCOSE BLOOD LEVEL; HEAT SHOCK PROTEIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; NUCLEAR PROTEIN; RAGA PROTEIN, RAT; SESTRIN 1 PROTEIN, RAT; SESTRIN 2 PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXPOSURE; LIPID DIET; LIVER; MALE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ADVERSE EFFECTS; ANIMAL; GENETICS; GLUCOSE BLOOD LEVEL; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

AMINO ACIDS; ANIMALS; BLOOD GLUCOSE; CELL CYCLE PROTEINS; DIET, HIGH-FAT; HEAT-SHOCK PROTEINS; IMMUNOPRECIPITATION; LIVER; MALE; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84949650037     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.115.215491     Document Type: Article

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