Hepatoprotective role of Sestrin2 against chronic ER stress

Nature Communications

Volumn 5, Issue , 2014, Pages

  Park, Hwan Woo ^a   Park, Haeli ^a   Ro, Seung Hyun ^a   Jang, Insook ^a   Semple, Ian A ^a   Kim, David N ^a   Kim, Myungjin ^a   Nam, Myeongjin ^a,b   Zhang, Deqiang ^a   Yin, Lei ^a   Lee, Jun Hee ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BUTYLATED HYDROXYANISOLE; CCAAT ENHANCER BINDING PROTEIN BETA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN; RAPAMYCIN; SESTRIN 2 PROTEIN; UNCLASSIFIED DRUG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; NUCLEAR PROTEIN; REACTIVE OXYGEN METABOLITE; SESN2 PROTEIN, HUMAN; SESTRIN 2 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

CYTOLOGY; FAT; GENE EXPRESSION; INHIBITION; MAMMAL; OBESITY; PATHOLOGY; PROTEIN; RODENT;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HEPATITIS; HOMEOSTASIS; LIPID STORAGE; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; UNFOLDED PROTEIN RESPONSE; WILD TYPE; ANIMAL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; FATTY LIVER; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; HEPG2 CELL LINE; HUMAN; INFLAMMATION; KNOCKOUT MOUSE; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; HEP G2 CELLS; HEPATOCYTES; HOMEOSTASIS; HUMANS; INFLAMMATION; INSULIN; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; OBESITY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UNFOLDED PROTEIN RESPONSE;

EID: 84903166942     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5233     Document Type: Article

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