Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase

Journal of Biological Chemistry

Volumn 279, Issue 52, 2004, Pages 54103-54109

  Kimball, Scot R ^a   Siegfried, Brett A ^a   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GLUCOSE; INSULIN; METABOLISM; PROTEINS; SIGNALING; SUBSTRATES;

MAMMALIAN TARGET OF REPAMYCIN (MTOR); PLASMA GLUCOSE; PROTEIN KINASE;

BIOCHEMISTRY;

GLUCAGON; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 4E; INSULIN; MAMMALIN TARGET OF RAPAMYCIN KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN S6K1; RPS6 KINASE; S6 KINASE; TARGET OF RAPAMYCIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HORMONE ACTION; LIVER FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

AMINO ACIDS; ANIMALS; CARRIER PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GLUCAGON; LIVER; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION;

ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 11144219992     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410755200     Document Type: Article

References (53)

1. Bollen, M., Keppens, S., and Stalmans, W. (1998) Biochem. J. 336, 19-31
2. Couet, C., Fukagawa, N. K., Matthews, D. E., Bier, D. M., and Young, V. R. (1990) Am. J. Physiol. 258, E78-E85
3. Flakoll, P. J., Borel, M. J., Wentzel, L. S., Williams, P. E., Lacy, D. B., and Abumrad, N. N. (1994) Metabolism 43, 1509-1516
4. Charlton, M. R., Adey, D. B., and Nair, K. S. (1996) J. Clin. Investig. 98, 90-99
5. Nair, K. S., Ford, G. C., Ekberg, K., Fernqvist-Forbes, E., and Wahren, J. (1995) J. Clin. Investig. 95, 2926-2937
6. Woodside, K. H., Ward, W. F., and Mortimore, G. E. (1974) J. Biol. Chem. 249, 5458-5463
7. Dixon, M., Agius, L., Yeaman, S. J., and Day, C. P. (1999) Hepatology 29, 1418-1424
8. Jeno, P., Ballou, L. M., Novak-Hofer, I., and Thomas, G. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 406-410
9. Raught, B., Peiretti, F., Gingras, A.-C., Livingstone, M., Shahbazian, D., Mayeur, G. L., Polakiewicz, R. D., Sonenberg, N., and Hershey, J. W. (2004) EMBO J. 23, 1761-1769
10. Meyuhas, O. (2000) Eur. J. Biochem. 267, 6321-6330
11. Gingras, A.-C., Gygi, S. P., Raught, B., Polakeiwicz, R. D., Abraham, R. T., Hoekstra, M. F., Aebersold, R., and Sonenberg, N. (1999) Genes Dev. 13, 1422-1437
12. Gingras, A.-C., Raught, B., and Sonenberg, N. (2001) Genes Dev. 15, 807-826
13. Bolster, D. R., Crozier, S. J., Kimball, S. R., and Jefferson, L. S. (2002) J. Biol. Chem. 277, 23977-23980
14. Dubbelhuis, P. F., and Meijer, A. J. (2002) FEBS Lett. 521, 39-42
15. Krause, U., Bertrand, L., and Hue, L. (2002) Eur. J. Biochem. 269, 3751-3759
16. Rimura, N., Tokunaga, C., Dalal, S., Richardson, C., Yoshino, K.-i., Kara, K., Kemp, B. E., Witters, L. A., Mimura, O., and Yonezawa, K. (2003) Genes Cells 8, 65-79
17. Shaw, R. J., Bardeesy, N., Manning, B. D., Lopez, L., Kosmatka, M., DePinho, R. A., and Cantley, L. C. (2004) Cancer Cells 6, 91-99
18. Hardie, D. G., Scott, J. W., Pan, D. A., and Hudson, E. R. (2003) FEBS Lett. 546, 113-120
19. Hawley, S. A., Boudeau, J., Reid, J. L., Mustard, K. J., Udd, L., Makela, T. P., Alessi, D. R., and Hardie, D. G. (2003) J. Biol. 2, 28.21-28.15
20. Collins, S. P., Reoma, J. L., Gamm, D.M., and Uhler, M. D. (2000) Biochem. J. 345, 673-680
21. Sapkota, G. P., Kieloch, A., Lizcano, J. M., Lain, S., Arthur, J. S. C., Williams, M. R., Morrice, N., Deak, M., and Alessi, D. R. (2001) J. Biol. Chem. 276, 19469-19482
22. Jiang, Y., Cypess, A. M., Muse, E. D., Wu, C.-R., Unson, C. G., Merrifield, R. B., and Sakmar, T. P. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10102-10107
23. Dalle, S., Longuet, C., Costes, S., Broca, C., Faruque, O., Fontes, G., Hani, E. H., and Bataille, D. (2004) J. Biol. Chem. 279, 20345-20355
24. Li, Y., Inoki, K, Vacratsis, P., and Guan, K.-L. (2003) J. Biol. Chem. 278, 13663-13671
25. Tee, A. R., Anjum, R., and Blenis, J. (2003) J. Biol. Chem. 278, 37288-37296
26. Roux, P. P., Ballif, B. A., Anjum, R., Gygi, S. P., and Blenis, J. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 13489-13494
27. Frodin, M., and Gammeltoft, S. (1999) Mol. Cell. Endocrinol. 151, 65-77
28. Jefferies, H. B. J., and Thomas, G. (1996) in Translational Control of Gene Expression (Hershey, J. W. B., Mathews, M. B., and Sonenberg, N., eds) Vol. 30, pp. 389-409, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
29. Kimball, S. R., Jurasinski, C. V., Lawrence, J. C., and Jefferson, L. S. (1997) Am. J. Physiol. 272, C754-C759
30. Exton, J. H. (1975) Methods Enzymol. 39, 25-36
31. Feldhoff, R. C., Taylor, J. M., and Jefferson, L. S. (1977) J. Biol. Chem. 252, 3611-3616
32. Tolman, E. L., Schworer, C. M., and Jefferson, L. S. (1973) J. Biol. Chem. 248, 4552-4560
33. Jelinek, L. J., Lok, S., Rosenberg, G. B., Smith, R. A., Grant, F. J., Biggs, S., Bensch, P. A., Kuijper, J. L., Sheppard, P. O., Sprecher, C. A., O'Hara, P. J., Foster, D., Walker, K. M., Chen, L. H. J., McKernan, P. A., and Kindsvogel, W. (1993) Science 259, 1614-1616
34. Yin, W., Mu, J., and Birnbaum, M. J. (2003) J. Biol. Chem. 278, 43074-43080
35. Yoshizawa, F., Kimball, S. R., Vary, T. C., and Jefferson, L. S. (1998) Am. J. Physiol. 275, E814-E820
36. Anthony, J. C., Yoshizawa, F., Anthony, T. G., Vary, T. C., Jefferson, L. S., and Kimball, S. R. (2000) J. Nutr. 130, 2413-2419
37. Kimball, S. R., Jefferson, L. S., and Davis, T. A. (2000) Am. J. Physiol 279, E1080-E1087
38. Mothe-Satney, I., Gautier, N., Hinault, C., Lawrence, J. C., and Van Obberghen, E. (2004) J. Biol. Chem. 279, 42628-42637
39. Boudeau, J., Sapkota, G. P., and Alessi, D. R. (2003) FEBS Lett. 546, 159-165
40. Yoo, L. I., Chung, D. C., and Yuan, J. (2002) Nat. Rev. Cancer 2, 529-535
41. Kwiatkowski, D. J. (2003) Ann. Hum. Genet. 67, 87-96
42. Sampson, J. R. (2003) Biochem. Soc. Trans. 31, 592-596
43. Kwiatkowski, D. J. (2003) Cancer Biol. Ther. 2, 471-476
44. Manning, B. D., and Cantley, L. C. (2003) Trends Biochem. Sci. 28, 573-575
45. Garami, A., Zwartkruis, F. J. T., Nobukuni, T., Joaquin, M., Roccio, M., Stocker, H., Kozma, S. C., Hafen, E., Bos, J. L., and Thomas, G. (2003) Mol. Cell 11, 1457-1466
46. Inoki, K., Li, Y., Xu, T., and Guan, K.-L. (2003) Genes Dev. 17, 1829-1834
47. Inoki, K., Zhu, T., and Guan, K.-L. (2003) Cell 115, 577-590
48. Pende, M., Um, S. H., Mieulet, V., Sticker, M., Goss, V. L., Mestan, J., Mueller, M., Fumagalli, S., Kozma, S. C., and Thomas, G. (2004) Mol. Cell Biol. 24, 3112-3124
49. Fumagalli, S., and Thomas, G. (2000) in Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B., and Mathews, M. B., eds) pp. 695-717, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
50. Meyuhas, O., and Hornstein, E. (2000) in Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B., and Mathews, M. B., eds) pp. 671-693, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
51. Lawson, T., Lee, K, Maimone, M., Abramson, R., Dever, T. E., Merrick, W. C., and Thach, R. (1989) Biochemistry 28, 4729-4734
52. Rogers, G. W., Jr., Richter, N. J., and Merrick, W. C. (1999) J. Biol. Chem. 274, 12236-12244
53. Rogers, G. W., Jr., Richter, N. J., Lima, W. F., and Merrick, W. C. (2001) J. Biol. Chem. 276, 30914-30922