Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Liren ^a,b   Shao, Yanjiao ^a   Guan, Yuting ^a   Li, Liang ^a   Wu, Lijuan ^a   Chen, Fangrui ^a   Liu, Meizhen ^a   Chen, Huaqing ^a   Ma, Yanlin ^c   Ma, Xueyun ^a   Liu, Mingyao ^a,d   Li, Dali ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b East China Normal University   (China)

^c HAINAN MEDICAL UNIVERSITY   (China)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; CRISPR CAS SYSTEM; CYTOLOGY; GENE DELETION; GENE LOCUS; GENE TARGETING; MAMMALIAN EMBRYO; METABOLISM; MOUSE; PROCEDURES; RAT; ZYGOTE;

ANIMALS; CRISPR-CAS SYSTEMS; EMBRYO, MAMMALIAN; GENE DELETION; GENE KNOCK-IN TECHNIQUES; GENETIC LOCI; MICE; RATS; ZYGOTE;

EID: 84949211352     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep17517     Document Type: Article

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