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Volumn 8, Issue OCT, 2014, Pages

Obesity and cognitive decline: Role of inflammation and vascular changes

Author keywords

Alzheimer's disease; Cytokines; Dementia; Hippocampus; Memory; Neuroinflammation

Indexed keywords

TAU PROTEIN;

EID: 84949117755     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2014.00375     Document Type: Article
Times cited : (297)

References (139)
  • 1
    • 84879731698 scopus 로고    scopus 로고
    • Vitamin E prevents highfat high-carbohydrates diet-induced memory impairment: the role of oxidative stress
    • Alzoubi, K.H., Khabour, O.F., Salah, H.A., and Hasan, Z. (2013). Vitamin E prevents highfat high-carbohydrates diet-induced memory impairment: the role of oxidative stress. Physiol Behav 119, 72-78. doi: 10.1016/j.physbeh.2013.06.011.
    • (2013) Physiol Behav , vol.119 , pp. 72-78
    • Alzoubi, K.H.1    Khabour, O.F.2    Salah, H.A.3    Hasan, Z.4
  • 3
    • 84924047127 scopus 로고    scopus 로고
    • Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation
    • Andre, C., Dinel, A.L., Ferreira, G., Laye, S., and Castanon, N. (2014). Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation. Brain Behav Immun. doi: 10.1016/j.bbi.2014.03.012.
    • (2014) Brain Behav Immun.
    • Andre, C.1    Dinel, A.L.2    Ferreira, G.3    Laye, S.4    Castanon, N.5
  • 4
    • 79954996833 scopus 로고    scopus 로고
    • Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
    • Anstey, K.J., Cherbuin, N., Budge, M., and Young, J. (2011). Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes Rev 12, e426-437. doi: 10.1111/j.1467-789X.2010.00825.x.
    • (2011) Obes Rev , vol.12 , pp. e426-437
    • Anstey, K.J.1    Cherbuin, N.2    Budge, M.3    Young, J.4
  • 5
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh, P., Braun, A., and Nedergaard, M. (2004). The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 16, 1-13. doi: 10.1016/j.nbd.2003.12.016.
    • (2004) Neurobiol Dis , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 6
    • 54149094094 scopus 로고    scopus 로고
    • Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier
    • Banks, W.A., Burney, B.O., and Robinson, S.M. (2008). Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier. Peptides 29, 2061-2065. doi: DOI 10.1016/j.peptides.2008.07.001.
    • (2008) Peptides , vol.29 , pp. 2061-2065
    • Banks, W.A.1    Burney, B.O.2    Robinson, S.M.3
  • 8
    • 0024824922 scopus 로고
    • Patterns of gliosis in Alzheimer's disease and aging cerebrum
    • Beach, T.G., Walker, R., and Mcgeer, E.G. (1989). Patterns of gliosis in Alzheimer's disease and aging cerebrum. Glia 2, 420-436. doi: 10.1002/glia.440020605.
    • (1989) Glia , vol.2 , pp. 420-436
    • Beach, T.G.1    Walker, R.2    Mcgeer, E.G.3
  • 9
    • 84894477354 scopus 로고    scopus 로고
    • Body mass index, weight change, and clinical progression in mild cognitive impairment and Alzheimer disease
    • Besser, L.M., Gill, D.P., Monsell, S.E., Brenowitz, W., Meranus, D.H., Kukull, W., and Gustafson, D.R. (2014). Body mass index, weight change, and clinical progression in mild cognitive impairment and Alzheimer disease. Alzheimer Dis Assoc Disord 28, 36-43. doi: 10.1097/wad.0000000000000005.
    • (2014) Alzheimer Dis Assoc Disord , vol.28 , pp. 36-43
    • Besser, L.M.1    Gill, D.P.2    Monsell, S.E.3    Brenowitz, W.4    Meranus, D.H.5    Kukull, W.6    Gustafson, D.R.7
  • 10
    • 42749100518 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for Alzheimer's disease
    • CD005593
    • Birks, J. (2006). Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev, CD005593. doi: 10.1002/14651858.CD005593.
    • (2006) Cochrane Database Syst Rev
    • Birks, J.1
  • 11
    • 0025339140 scopus 로고
    • Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors
    • Blennow, K., Wallin, A., Fredman, P., Karlsson, I., Gottfries, C.G., and Svennerholm, L. (1990). Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors. Acta Neurol Scand 81, 323-326.
    • (1990) Acta Neurol Scand , vol.81 , pp. 323-326
    • Blennow, K.1    Wallin, A.2    Fredman, P.3    Karlsson, I.4    Gottfries, C.G.5    Svennerholm, L.6
  • 12
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • Bliss, T.V., and Collingridge, G.L. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39. doi: 10.1038/361031a0.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 13
    • 84904126101 scopus 로고    scopus 로고
    • Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats
    • Boitard, C., Cavaroc, A., Sauvant, J., Aubert, A., Castanon, N., Laye, S., and Ferreira, G. (2014). Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats. Brain Behavior and Immunity 40, 9-17. doi: DOI 10.1016/j.bbi.2014.03.005.
    • (2014) Brain Behavior and Immunity , vol.40 , pp. 9-17
    • Boitard, C.1    Cavaroc, A.2    Sauvant, J.3    Aubert, A.4    Castanon, N.5    Laye, S.6    Ferreira, G.7
  • 14
    • 25444473999 scopus 로고    scopus 로고
    • Change in body mass index and risk of incident Alzheimer disease
    • Buchman, A.S., Wilson, R.S., Bienias, J.L., Shah, R.C., Evans, D.A., and Bennett, D.A. (2005). Change in body mass index and risk of incident Alzheimer disease. Neurology 65, 892-897. doi: 10.1212/01.wnl.0000176061.33817.90.
    • (2005) Neurology , vol.65 , pp. 892-897
    • Buchman, A.S.1    Wilson, R.S.2    Bienias, J.L.3    Shah, R.C.4    Evans, D.A.5    Bennett, D.A.6
  • 15
    • 84901853714 scopus 로고    scopus 로고
    • Short-term high-fat-and-fructose feeding produces insulin signaling alterations accompanied by neurite and synaptic reduction and astroglial activation in the rat hippocampus
    • Calvo-Ochoa, E., Hernandez-Ortega, K., Ferrera, P., Morimoto, S., and Arias, C. (2014). Short-term high-fat-and-fructose feeding produces insulin signaling alterations accompanied by neurite and synaptic reduction and astroglial activation in the rat hippocampus. J Cereb Blood Flow Metab 34, 1001-1008. doi: 10.1038/jcbfm.2014.48.
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 1001-1008
    • Calvo-Ochoa, E.1    Hernandez-Ortega, K.2    Ferrera, P.3    Morimoto, S.4    Arias, C.5
  • 16
    • 84920644057 scopus 로고    scopus 로고
    • Morphological changes in glial fibrillary acidic protein immunopositive astrocytes in the hippocampus of dietary-induced obese mice
    • Cano, V., Valladolid-Acebes, I., Hernandez-Nuno, F., Merino, B., Del Olmo, N., Chowen, J.A., and Ruiz-Gayo, M. (2014). Morphological changes in glial fibrillary acidic protein immunopositive astrocytes in the hippocampus of dietary-induced obese mice. Neuroreport 25, 819-822. doi: Doi 10.1097/Wnr.0000000000000180.
    • (2014) Neuroreport , vol.25 , pp. 819-822
    • Cano, V.1    Valladolid-Acebes, I.2    Hernandez-Nuno, F.3    Merino, B.4    Del Olmo, N.5    Chowen, J.A.6    Ruiz-Gayo, M.7
  • 17
    • 84905499874 scopus 로고    scopus 로고
    • Neuropsychiatric comorbidity in obesity: role of inflammatory processes
    • Castanon, N., Lasselin, J., and Capuron, L. (2014). Neuropsychiatric comorbidity in obesity: role of inflammatory processes. Front Endocrinol (Lausanne) 5, 74. doi: 10.3389/fendo.2014.00074.
    • (2014) Front Endocrinol (Lausanne) , vol.5 , pp. 74
    • Castanon, N.1    Lasselin, J.2    Capuron, L.3
  • 18
    • 33749861878 scopus 로고    scopus 로고
    • Relation between body mass index and cognitive function in healthy middle-aged men and women
    • Cournot, M., Marquie, J.C., Ansiau, D., Martinaud, C., Fonds, H., Ferrieres, J., and Ruidavets, J.B. (2006). Relation between body mass index and cognitive function in healthy middle-aged men and women. Neurology 67, 1208-1214. doi: 10.1212/01.wnl.0000238082.13860.50.
    • (2006) Neurology , vol.67 , pp. 1208-1214
    • Cournot, M.1    Marquie, J.C.2    Ansiau, D.3    Martinaud, C.4    Fonds, H.5    Ferrieres, J.6    Ruidavets, J.B.7
  • 19
    • 26444604608 scopus 로고    scopus 로고
    • Rivastigmine for vascular cognitive impairment
    • CD004744.
    • Craig, D., and Birks, J. (2005). Rivastigmine for vascular cognitive impairment. Cochrane Database Syst Rev, CD004744. doi: 10.1002/14651858.CD004744.pub2.
    • (2005) Cochrane Database Syst Rev
    • Craig, D.1    Birks, J.2
  • 20
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer, R., O'connor, J.C., Freund, G.G., Johnson, R.W., and Kelley, K.W. (2008). From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9, 46-56. doi: 10.1038/nrn2297.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 21
    • 84861933896 scopus 로고    scopus 로고
    • The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood-brain barrier integrity differ for diet-induced obese and dietresistant rats
    • Davidson, T.L., Monnot, A., Neal, A.U., Martin, A.A., Horton, J.J., and Zheng, W. (2012). The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood-brain barrier integrity differ for diet-induced obese and dietresistant rats. Physiol Behav 107, 26-33. doi: 10.1016/j.physbeh.2012.05.015.
    • (2012) Physiol Behav , vol.107 , pp. 26-33
    • Davidson, T.L.1    Monnot, A.2    Neal, A.U.3    Martin, A.A.4    Horton, J.J.5    Zheng, W.6
  • 22
    • 70349217937 scopus 로고    scopus 로고
    • Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC)
    • De Hert, M., Dekker, J.M., Wood, D., Kahl, K.G., Holt, R.I., and Moller, H.J. (2009). Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur Psychiatry 24, 412-424. doi: 10.1016/j.eurpsy.2009.01.005.
    • (2009) Eur Psychiatry , vol.24 , pp. 412-424
    • De Hert, M.1    Dekker, J.M.2    Wood, D.3    Kahl, K.G.4    Holt, R.I.5    Moller, H.J.6
  • 23
    • 78649236899 scopus 로고    scopus 로고
    • Depressive and anxiety disorders and the association with obesity, physical, and social activities
    • De Wit, L.M., Fokkema, M., Van Straten, A., Lamers, F., Cuijpers, P., and Penninx, B.W. (2010). Depressive and anxiety disorders and the association with obesity, physical, and social activities. Depress Anxiety 27, 1057-1065. doi: 10.1002/da.20738.
    • (2010) Depress Anxiety , vol.27 , pp. 1057-1065
    • De Wit, L.M.1    Fokkema, M.2    Van Straten, A.3    Lamers, F.4    Cuijpers, P.5    Penninx, B.W.6
  • 24
    • 80051508807 scopus 로고    scopus 로고
    • Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline
    • Debette, S., Seshadri, S., Beiser, A., Au, R., Himali, J.J., Palumbo, C., Wolf, P.A., and Decarli, C. (2011). Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology 77, 461-468. doi: Doi 10.1212/Wnl.0b013e318227b227.
    • (2011) Neurology , vol.77 , pp. 461-468
    • Debette, S.1    Seshadri, S.2    Beiser, A.3    Au, R.4    Himali, J.J.5    Palumbo, C.6    Wolf, P.A.7    Decarli, C.8
  • 25
    • 77950829087 scopus 로고    scopus 로고
    • A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline
    • Den Heijer, T., Van Der Lijn, F., Koudstaal, P.J., Hofman, A., Van Der Lugt, A., Krestin, G.P., Niessen, W.J., and Breteler, M.M. (2010). A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain 133, 1163-1172. doi: 10.1093/brain/awq048.
    • (2010) Brain , vol.133 , pp. 1163-1172
    • Den Heijer, T.1    Van Der Lijn, F.2    Koudstaal, P.J.3    Hofman, A.4    Van Der Lugt, A.5    Krestin, G.P.6    Niessen, W.J.7    Breteler, M.M.8
  • 27
    • 80052838069 scopus 로고    scopus 로고
    • Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome
    • Dinel, A.L., Andre, C., Aubert, A., Ferreira, G., Laye, S., and Castanon, N. (2011). Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome. PLoS One 6, e24325. doi: 10.1371/journal.pone.0024325.
    • (2011) PLoS One , vol.6 , pp. e24325
    • Dinel, A.L.1    Andre, C.2    Aubert, A.3    Ferreira, G.4    Laye, S.5    Castanon, N.6
  • 29
    • 0034084815 scopus 로고    scopus 로고
    • The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort
    • Elias, M.F., Beiser, A., Wolf, P.A., Au, R., White, R.F., and D'agostino, R.B. (2000). The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort. Arch Neurol 57, 808-813.
    • (2000) Arch Neurol , vol.57 , pp. 808-813
    • Elias, M.F.1    Beiser, A.2    Wolf, P.A.3    Au, R.4    White, R.F.5    D'agostino, R.B.6
  • 30
    • 0037327636 scopus 로고    scopus 로고
    • Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study
    • Elias, M.F., Elias, P.K., Sullivan, L.M., Wolf, P.A., and D'agostino, R.B. (2003). Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study. Int J Obes Relat Metab Disord 27, 260-268.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 260-268
    • Elias, M.F.1    Elias, P.K.2    Sullivan, L.M.3    Wolf, P.A.4    D'agostino, R.B.5
  • 32
    • 80053383804 scopus 로고    scopus 로고
    • Depression in dementia: epidemiology, mechanisms, and treatment
    • Enache, D., Winblad, B., and Aarsland, D. (2011). Depression in dementia: epidemiology, mechanisms, and treatment. Curr Opin Psychiatry 24, 461-472. doi: 10.1097/YCO.0b013e32834bb9d4.
    • (2011) Curr Opin Psychiatry , vol.24 , pp. 461-472
    • Enache, D.1    Winblad, B.2    Aarsland, D.3
  • 33
    • 84893666444 scopus 로고    scopus 로고
    • Obesity elicits interleukin 1-mediated deficits in hippocampal synaptic plasticity
    • Erion, J.R., Wosiski-Kuhn, M., Dey, A., Hao, S., Davis, C.L., Pollock, N.K., and Stranahan, A.M. (2014). Obesity elicits interleukin 1-mediated deficits in hippocampal synaptic plasticity. J Neurosci 34, 2618-2631. doi: 10.1523/JNEUROSCI.4200-13.2014.
    • (2014) J Neurosci , vol.34 , pp. 2618-2631
    • Erion, J.R.1    Wosiski-Kuhn, M.2    Dey, A.3    Hao, S.4    Davis, C.L.5    Pollock, N.K.6    Stranahan, A.M.7
  • 36
    • 84859428464 scopus 로고    scopus 로고
    • Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet
    • Freeman, L.R., and Granholm, A.C. (2012). Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet. J Cereb Blood Flow Metab 32, 643-653. doi: 10.1038/jcbfm.2011.168jcbfm2011168 [pii].
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 643-653
    • Freeman, L.R.1    Granholm, A.C.2
  • 39
    • 34447549299 scopus 로고    scopus 로고
    • Interleukin-1beta and caspase-1: players in the regulation of age-related cognitive dysfunction
    • Gemma, C., and Bickford, P.C. (2007). Interleukin-1beta and caspase-1: players in the regulation of age-related cognitive dysfunction. Rev Neurosci 18, 137-148.
    • (2007) Rev Neurosci , vol.18 , pp. 137-148
    • Gemma, C.1    Bickford, P.C.2
  • 40
    • 54049149226 scopus 로고    scopus 로고
    • Changes in Cognitive Function in Human Aging
    • ed. D.R. Riddle. (Boca Raton (FL)).
    • Glisky, E.L. (2007). "Changes in Cognitive Function in Human Aging," in Brain Aging: Models, Methods, and Mechanisms, ed. D.R. Riddle. (Boca Raton (FL)).
    • (2007) Brain Aging: Models, Methods, and Mechanisms
    • Glisky, E.L.1
  • 42
    • 47849114072 scopus 로고    scopus 로고
    • Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat
    • Granholm, A.C., Bimonte-Nelson, H.A., Moore, A.B., Nelson, M.E., Freeman, L.R., and Sambamurti, K. (2008). Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat. J Alzheimers Dis 14, 133-145.
    • (2008) J Alzheimers Dis , vol.14 , pp. 133-145
    • Granholm, A.C.1    Bimonte-Nelson, H.A.2    Moore, A.B.3    Nelson, M.E.4    Freeman, L.R.5    Sambamurti, K.6
  • 43
    • 2942675088 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome, and cardiovascular disease
    • Grundy, S.M. (2004). Obesity, metabolic syndrome, and cardiovascular disease. Journal of Clinical Endocrinology & Metabolism 89, 2595-2600. doi: Doi 10.1210/Jc.2004- 0372.
    • (2004) Journal of Clinical Endocrinology & Metabolism , vol.89 , pp. 2595-2600
    • Grundy, S.M.1
  • 44
    • 37849185832 scopus 로고    scopus 로고
    • Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
    • Gunstad, J., Paul, R.H., Cohen, R.A., Tate, D.F., Spitznagel, M.B., and Gordon, E. (2007). Elevated body mass index is associated with executive dysfunction in otherwise healthy adults. Comprehensive Psychiatry 48, 57-61. doi: DOI 10.1016/j.comppsych.2006.05.001.
    • (2007) Comprehensive Psychiatry , vol.48 , pp. 57-61
    • Gunstad, J.1    Paul, R.H.2    Cohen, R.A.3    Tate, D.F.4    Spitznagel, M.B.5    Gordon, E.6
  • 45
  • 46
    • 0038494075 scopus 로고    scopus 로고
    • An 18-year follow-up of overweight and risk of Alzheimer disease
    • Gustafson, D., Rothenberg, E., Blennow, K., Steen, B., and Skoog, I. (2003). An 18-year follow-up of overweight and risk of Alzheimer disease. Arch Intern Med 163, 1524- 1528. doi: 10.1001/archinte.163.13.1524.
    • (2003) Arch Intern Med , vol.163 , pp. 1524- 1528
    • Gustafson, D.1    Rothenberg, E.2    Blennow, K.3    Steen, B.4    Skoog, I.5
  • 47
    • 84855781454 scopus 로고    scopus 로고
    • 37 years of body mass index and dementia: observations from the prospective population study of women in Gothenburg, Sweden
    • Gustafson, D.R., Backman, K., Joas, E., Waern, M., Ostling, S., Guo, X., and Skoog, I. (2012). 37 years of body mass index and dementia: observations from the prospective population study of women in Gothenburg, Sweden. J Alzheimers Dis 28, 163-171. doi: 10.3233/jad-2011-110917.
    • (2012) J Alzheimers Dis , vol.28 , pp. 163-171
    • Gustafson, D.R.1    Backman, K.2    Joas, E.3    Waern, M.4    Ostling, S.5    Guo, X.6    Skoog, I.7
  • 49
    • 36248939638 scopus 로고    scopus 로고
    • Mid-life adiposity factors relate to blood-brain barrier integrity in late life
    • Gustafson, D.R., Karlsson, C., Skoog, I., Rosengren, L., Lissner, L., and Blennow, K. (2007). Mid-life adiposity factors relate to blood-brain barrier integrity in late life. J Intern Med 262, 643-650. doi: 10.1111/j.1365-2796.2007.01869.x.
    • (2007) J Intern Med , vol.262 , pp. 643-650
    • Gustafson, D.R.1    Karlsson, C.2    Skoog, I.3    Rosengren, L.4    Lissner, L.5    Blennow, K.6
  • 50
    • 84886914486 scopus 로고    scopus 로고
    • Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat
    • Hansen, H.H., Jensen, M.M., Overgaard, A., Weikop, P., and Mikkelsen, J.D. (2013). Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat. Pharmacol Biochem Behav 110, 265-271. doi: 10.1016/j.pbb.2013.07.018.
    • (2013) Pharmacol Biochem Behav , vol.110 , pp. 265-271
    • Hansen, H.H.1    Jensen, M.M.2    Overgaard, A.3    Weikop, P.4    Mikkelsen, J.D.5
  • 51
    • 84922617580 scopus 로고    scopus 로고
    • Peripheral Inflammation Acutely Impairs Human Spatial Memory via Actions on Medial Temporal Lobe Glucose Metabolism
    • Harrison, N.A., Doeller, C.F., Voon, V., Burgess, N., and Critchley, H.D. (2014). Peripheral Inflammation Acutely Impairs Human Spatial Memory via Actions on Medial Temporal Lobe Glucose Metabolism. Biol Psychiatry 76, 585-593. doi: 10.1016/j.biopsych.2014.01.005.
    • (2014) Biol Psychiatry , vol.76 , pp. 585-593
    • Harrison, N.A.1    Doeller, C.F.2    Voon, V.3    Burgess, N.4    Critchley, H.D.5
  • 52
    • 25844457693 scopus 로고    scopus 로고
    • Obesity
    • Haslam, D.W., and James, W.P.T. (2005). Obesity. Lancet 366, 1197-1209. doi: Doi 10.1016/S0140-6736(05)67483-1.
    • (2005) Lancet , vol.366 , pp. 1197-1209
    • Haslam, D.W.1    James, W.P.T.2
  • 53
    • 84871692604 scopus 로고    scopus 로고
    • Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians
    • Hasnain, M., Vieweg, W.V., and Hollett, B. (2012). Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians. Postgrad Med 124, 154-167. doi: 10.3810/pgm.2012.07.2577.
    • (2012) Postgrad Med , vol.124 , pp. 154-167
    • Hasnain, M.1    Vieweg, W.V.2    Hollett, B.3
  • 54
    • 77954191017 scopus 로고    scopus 로고
    • Overweight in midlife is related to lower cognitive function 30 years later: a prospective study with longitudinal assessments
    • Hassing, L.B., Dahl, A.K., Pedersen, N.L., and Johansson, B. (2010). Overweight in midlife is related to lower cognitive function 30 years later: a prospective study with longitudinal assessments. Dement Geriatr Cogn Disord 29, 543-552. doi: 10.1159/000314874.
    • (2010) Dement Geriatr Cogn Disord , vol.29 , pp. 543-552
    • Hassing, L.B.1    Dahl, A.K.2    Pedersen, N.L.3    Johansson, B.4
  • 55
    • 79956125681 scopus 로고    scopus 로고
    • Central adiposity rather than total adiposity measurements are specifically involved in the inflammatory status from healthy young adults
    • Hermsdorff, H.H., Zulet, M.A., Puchau, B., and Martinez, J.A. (2011). Central adiposity rather than total adiposity measurements are specifically involved in the inflammatory status from healthy young adults. Inflammation 34, 161-170. doi: 10.1007/s10753- 010-9219-y.
    • (2011) Inflammation , vol.34 , pp. 161-170
    • Hermsdorff, H.H.1    Zulet, M.A.2    Puchau, B.3    Martinez, J.A.4
  • 56
    • 84890428034 scopus 로고    scopus 로고
    • Associations between obesogenic risk factors and depression among adolescents: a systematic review
    • Hoare, E., Skouteris, H., Fuller-Tyszkiewicz, M., Millar, L., and Allender, S. (2014). Associations between obesogenic risk factors and depression among adolescents: a systematic review. Obesity Reviews 15, 40-51. doi: Doi 10.1111/Obr.12069.
    • (2014) Obesity Reviews , vol.15 , pp. 40-51
    • Hoare, E.1    Skouteris, H.2    Fuller-Tyszkiewicz, M.3    Millar, L.4    Allender, S.5
  • 57
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
    • Hotamisligil, G.S., Shargill, N.S., and Spiegelman, B.M. (1993). Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259, 87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 58
    • 84888788348 scopus 로고    scopus 로고
    • Metabolic disturbances connecting obesity and depression
    • Hryhorczuk, C., Sharma, S., and Fulton, S.E. (2013). Metabolic disturbances connecting obesity and depression. Front Neurosci 7, 177. doi: 10.3389/fnins.2013.00177.
    • (2013) Front Neurosci , vol.7 , pp. 177
    • Hryhorczuk, C.1    Sharma, S.2    Fulton, S.E.3
  • 59
    • 0014004384 scopus 로고
    • Diabetes, a new mutation in the mouse
    • Hummel, K.P., Dickie, M.M., and Coleman, D.L. (1966). Diabetes, a new mutation in the mouse. Science 153, 1127-1128.
    • (1966) Science , vol.153 , pp. 1127-1128
    • Hummel, K.P.1    Dickie, M.M.2    Coleman, D.L.3
  • 60
    • 0024436506 scopus 로고
    • Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
    • Itagaki, S., Mcgeer, P.L., Akiyama, H., Zhu, S., and Selkoe, D. (1989). Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J Neuroimmunol 24, 173-182.
    • (1989) J Neuroimmunol , vol.24 , pp. 173-182
    • Itagaki, S.1    Mcgeer, P.L.2    Akiyama, H.3    Zhu, S.4    Selkoe, D.5
  • 62
    • 84879332355 scopus 로고    scopus 로고
    • Serum Amyloid A is Found on ApoB-Containing Lipoproteins in Obese Humans with Diabetes
    • Jahangiri, A., Wilson, P.G., Hou, T.F., Brown, A., King, V.L., and Tannock, L.R. (2013). Serum Amyloid A is Found on ApoB-Containing Lipoproteins in Obese Humans with Diabetes. Obesity 21, 993-996. doi: Doi 10.1002/Oby.20126.
    • (2013) Obesity , vol.21 , pp. 993-996
    • Jahangiri, A.1    Wilson, P.G.2    Hou, T.F.3    Brown, A.4    King, V.L.5    Tannock, L.R.6
  • 63
    • 0032590178 scopus 로고    scopus 로고
    • Cytokine and growth factor involvement in long-term potentiation
    • Jankowsky, J.L., and Patterson, P.H. (1999). Cytokine and growth factor involvement in long-term potentiation. Mol Cell Neurosci 14, 273-286.
    • (1999) Mol Cell Neurosci , vol.14 , pp. 273-286
    • Jankowsky, J.L.1    Patterson, P.H.2
  • 64
    • 84876137618 scopus 로고    scopus 로고
    • Synergistic Relationships among Stress, Depression, and Troubled Relationships: Insights from Psychoneuroimmunology
    • Jaremka, L.M., Lindgren, M.E., and Kiecolt-Glaser, J.K. (2013). Synergistic Relationships among Stress, Depression, and Troubled Relationships: Insights from Psychoneuroimmunology. Depression and Anxiety 30, 288-296. doi: Doi 10.1002/Da.22078.
    • (2013) Depression and Anxiety , vol.30 , pp. 288-296
    • Jaremka, L.M.1    Lindgren, M.E.2    Kiecolt-Glaser, J.K.3
  • 65
    • 84861846116 scopus 로고    scopus 로고
    • Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a highfat diet
    • Jeon, B.T., Jeong, E.A., Shin, H.J., Lee, Y., Lee, D.H., Kim, H.J., Kang, S.S., Cho, G.J., Choi, W.S., and Roh, G.S. (2012). Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a highfat diet. Diabetes 61, 1444-1454. doi: 10.2337/db11-1498.
    • (2012) Diabetes , vol.61 , pp. 1444-1454
    • Jeon, B.T.1    Jeong, E.A.2    Shin, H.J.3    Lee, Y.4    Lee, D.H.5    Kim, H.J.6    Kang, S.S.7    Cho, G.J.8    Choi, W.S.9    Roh, G.S.10
  • 67
    • 77954955083 scopus 로고    scopus 로고
    • High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model
    • Julien, C., Tremblay, C., Phivilay, A., Berthiaume, L., Emond, V., Julien, P., and Calon, F. (2010). High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model. Neurobiol Aging 31, 1516-1531. doi: 10.1016/j.neurobiolaging.2008.08.022.
    • (2010) Neurobiol Aging , vol.31 , pp. 1516-1531
    • Julien, C.1    Tremblay, C.2    Phivilay, A.3    Berthiaume, L.4    Emond, V.5    Julien, P.6    Calon, F.7
  • 68
    • 50449105836 scopus 로고    scopus 로고
    • Diet-induced obesity and spatial cognition in young male rats
    • Jurdak, N., Lichtenstein, A.H., and Kanarek, R.B. (2008). Diet-induced obesity and spatial cognition in young male rats. Nutr Neurosci 11, 48-54.
    • (2008) Nutr Neurosci , vol.11 , pp. 48-54
    • Jurdak, N.1    Lichtenstein, A.H.2    Kanarek, R.B.3
  • 69
    • 77950940297 scopus 로고    scopus 로고
    • Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet
    • Kanoski, S.E., and Davidson, T.L. (2010). Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet. J Exp Psychol Anim Behav Process 36, 313-319.
    • (2010) J Exp Psychol Anim Behav Process , vol.36 , pp. 313-319
    • Kanoski, S.E.1    Davidson, T.L.2
  • 70
    • 77954981010 scopus 로고    scopus 로고
    • The effects of a highenergy diet on hippocampal function and blood-brain barrier integrity in the rat
    • Kanoski, S.E., Zhang, Y., Zheng, W., and Davidson, T.L. (2010). The effects of a highenergy diet on hippocampal function and blood-brain barrier integrity in the rat. J Alzheimers Dis 21, 207-219. doi: 10.3233/JAD-2010-091414.
    • (2010) J Alzheimers Dis , vol.21 , pp. 207-219
    • Kanoski, S.E.1    Zhang, Y.2    Zheng, W.3    Davidson, T.L.4
  • 71
    • 84887141745 scopus 로고    scopus 로고
    • Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study
    • Karimi, S.A., Salehi, I., Komaki, A., Sarihi, A., Zarei, M., and Shahidi, S. (2013). Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study. Brain Res 1539, 1-6. doi: 10.1016/j.brainres.2013.09.029.
    • (2013) Brain Res , vol.1539 , pp. 1-6
    • Karimi, S.A.1    Salehi, I.2    Komaki, A.3    Sarihi, A.4    Zarei, M.5    Shahidi, S.6
  • 73
    • 84899826728 scopus 로고    scopus 로고
    • Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus
    • Koga, S., Kojima, A., Kuwabara, S., and Yoshiyama, Y. (2014). Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. Neurosci Lett 571, 11-16. doi: 10.1016/j.neulet.2014.04.028.
    • (2014) Neurosci Lett , vol.571 , pp. 11-16
    • Koga, S.1    Kojima, A.2    Kuwabara, S.3    Yoshiyama, Y.4
  • 74
    • 84864812652 scopus 로고    scopus 로고
    • Effect of western and high fat diets on memory and cholinergic measures in the rat
    • Kosari, S., Badoer, E., Nguyen, J.C., Killcross, A.S., and Jenkins, T.A. (2012). Effect of western and high fat diets on memory and cholinergic measures in the rat. Behav Brain Res 235, 98-103. doi: 10.1016/j.bbr.2012.07.017.
    • (2012) Behav Brain Res , vol.235 , pp. 98-103
    • Kosari, S.1    Badoer, E.2    Nguyen, J.C.3    Killcross, A.S.4    Jenkins, T.A.5
  • 75
    • 84875201745 scopus 로고    scopus 로고
    • The role of peripheral inflammatory markers in dementia and Alzheimer's disease: a metaanalysis
    • Koyama, A., O'brien, J., Weuve, J., Blacker, D., Metti, A.L., and Yaffe, K. (2013). The role of peripheral inflammatory markers in dementia and Alzheimer's disease: a metaanalysis. J Gerontol A Biol Sci Med Sci 68, 433-440. doi: 10.1093/gerona/gls187.
    • (2013) J Gerontol A Biol Sci Med Sci , vol.68 , pp. 433-440
    • Koyama, A.1    O'brien, J.2    Weuve, J.3    Blacker, D.4    Metti, A.L.5    Yaffe, K.6
  • 76
    • 71849089826 scopus 로고    scopus 로고
    • Plasma Amyloid-beta Peptide Levels Correlate with Adipocyte Amyloid Precursor Protein Gene Expression in Obese Individuals
    • Lee, Y.H., Martin, J.M., Maple, R.L., Tharp, W.G., and Pratley, R.E. (2009). Plasma Amyloid-beta Peptide Levels Correlate with Adipocyte Amyloid Precursor Protein Gene Expression in Obese Individuals. Neuroendocrinology 90, 383-390. doi: Doi 10.1159/000235555.
    • (2009) Neuroendocrinology , vol.90 , pp. 383-390
    • Lee, Y.H.1    Martin, J.M.2    Maple, R.L.3    Tharp, W.G.4    Pratley, R.E.5
  • 78
    • 84898041036 scopus 로고    scopus 로고
    • Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents
    • Liang, J., Matheson, B.E., Kaye, W.H., and Boutelle, K.N. (2014). Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents. Int J Obes (Lond) 38, 494-506. doi: 10.1038/ijo.2013.142.
    • (2014) Int J Obes (Lond) , vol.38 , pp. 494-506
    • Liang, J.1    Matheson, B.E.2    Kaye, W.H.3    Boutelle, K.N.4
  • 80
    • 77957086962 scopus 로고    scopus 로고
    • Role of Microglia in Neurotrauma
    • Loane, D.J., and Byrnes, K.R. (2010). Role of Microglia in Neurotrauma. Neurotherapeutics 7, 366-377.
    • (2010) Neurotherapeutics , vol.7 , pp. 366-377
    • Loane, D.J.1    Byrnes, K.R.2
  • 81
    • 70249093603 scopus 로고    scopus 로고
    • Evidence of executive dysfunction in extremely obese adolescents: a pilot study
    • Lokken, K.L., Boeka, A.G., Austin, H.M., Gunstad, J., and Harmon, C.M. (2009). Evidence of executive dysfunction in extremely obese adolescents: a pilot study. Surg Obes Relat Dis 5, 547-552. doi: 10.1016/j.soard.2009.05.008.
    • (2009) Surg Obes Relat Dis , vol.5 , pp. 547-552
    • Lokken, K.L.1    Boeka, A.G.2    Austin, H.M.3    Gunstad, J.4    Harmon, C.M.5
  • 82
    • 84887194572 scopus 로고    scopus 로고
    • Physical activity and the brain: A review of this dynamic, bi-directional relationship
    • Loprinzi, P.D., Herod, S.M., Cardinal, B.J., and Noakes, T.D. (2013). Physical activity and the brain: A review of this dynamic, bi-directional relationship. Brain Research 1539, 95-104. doi: DOI 10.1016/j.brainres.2013.10.004.
    • (2013) Brain Research , vol.1539 , pp. 95-104
    • Loprinzi, P.D.1    Herod, S.M.2    Cardinal, B.J.3    Noakes, T.D.4
  • 83
    • 33947195233 scopus 로고    scopus 로고
    • Measures of adiposity and dementia risk in elderly persons
    • Luchsinger, J.A., Patel, B., Tang, M.X., Schupf, N., and Mayeux, R. (2007). Measures of adiposity and dementia risk in elderly persons. Arch Neurol 64, 392-398. doi: 10.1001/archneur.64.3.392.
    • (2007) Arch Neurol , vol.64 , pp. 392-398
    • Luchsinger, J.A.1    Patel, B.2    Tang, M.X.3    Schupf, N.4    Mayeux, R.5
  • 84
    • 84887462053 scopus 로고    scopus 로고
    • Towards a Smart Population: A Public Health Framework for Cognitive Enhancement
    • Lucke, J., and Partridge, B. (2013). Towards a Smart Population: A Public Health Framework for Cognitive Enhancement. Neuroethics 6, 419-427. doi: DOI 10.1007/s12152-012- 9167-3.
    • (2013) Neuroethics , vol.6 , pp. 419-427
    • Lucke, J.1    Partridge, B.2
  • 85
    • 77649217019 scopus 로고    scopus 로고
    • Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies
    • Luppino, F.S., De Wit, L.M., Bouvy, P.F., Stijnen, T., Cuijpers, P., Penninx, B.W., and Zitman, F.G. (2010). Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 67, 220-229. doi: 10.1001/archgenpsychiatry.2010.2.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 220-229
    • Luppino, F.S.1    De Wit, L.M.2    Bouvy, P.F.3    Stijnen, T.4    Cuijpers, P.5    Penninx, B.W.6    Zitman, F.G.7
  • 86
    • 0037174346 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
    • Lyketsos, C.G., Lopez, O., Jones, B., Fitzpatrick, A.L., Breitner, J., and Dekosky, S. (2002). Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA 288, 1475-1483.
    • (2002) JAMA , vol.288 , pp. 1475-1483
    • Lyketsos, C.G.1    Lopez, O.2    Jones, B.3    Fitzpatrick, A.L.4    Breitner, J.5    Dekosky, S.6
  • 88
    • 78149325368 scopus 로고    scopus 로고
    • High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task
    • Mcneilly, A.D., Williamson, R., Sutherland, C., Balfour, D.J., and Stewart, C.A. (2011). High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task. Behav Brain Res 217, 134-141.
    • (2011) Behav Brain Res , vol.217 , pp. 134-141
    • Mcneilly, A.D.1    Williamson, R.2    Sutherland, C.3    Balfour, D.J.4    Stewart, C.A.5
  • 89
    • 80052090780 scopus 로고    scopus 로고
    • Obesity in adults with serious and persistent mental illness: a review of postulated mechanisms and current interventions
    • Megna, J.L., Schwartz, T.L., Siddiqui, U.A., and Herrera Rojas, M. (2011). Obesity in adults with serious and persistent mental illness: a review of postulated mechanisms and current interventions. Ann Clin Psychiatry 23, 131-140.
    • (2011) Ann Clin Psychiatry , vol.23 , pp. 131-140
    • Megna, J.L.1    Schwartz, T.L.2    Siddiqui, U.A.3    Herrera Rojas, M.4
  • 90
    • 84908651577 scopus 로고    scopus 로고
    • Obesity and neuroinflammation: A pathway to cognitive impairment
    • Miller, A.A., and Spencer, S.J. (2014). Obesity and neuroinflammation: A pathway to cognitive impairment. Brain Behav Immun. doi: 10.1016/j.bbi.2014.04.001.
    • (2014) Brain Behav Immun.
    • Miller, A.A.1    Spencer, S.J.2
  • 91
    • 0037135258 scopus 로고    scopus 로고
    • A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning
    • Molteni, R., Barnard, R.J., Ying, Z., Roberts, C.K., and Gomez-Pinilla, F. (2002). A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience 112, 803-814.
    • (2002) Neuroscience , vol.112 , pp. 803-814
    • Molteni, R.1    Barnard, R.J.2    Ying, Z.3    Roberts, C.K.4    Gomez-Pinilla, F.5
  • 92
    • 38049050406 scopus 로고    scopus 로고
    • Obesity and impairment in psychosocial functioning in women: the mediating role of eating disorder features
    • Mond, J.M., Rodgers, B., Hay, P.J., Darby, A., Owen, C., Baune, B.T., and Kennedy, R.L. (2007). Obesity and impairment in psychosocial functioning in women: the mediating role of eating disorder features. Obesity (Silver Spring) 15, 2769-2779. doi: 10.1038/oby.2007.329.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2769-2779
    • Mond, J.M.1    Rodgers, B.2    Hay, P.J.3    Darby, A.4    Owen, C.5    Baune, B.T.6    Kennedy, R.L.7
  • 94
    • 84864633293 scopus 로고    scopus 로고
    • Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption
    • Morganstern, I., Ye, Z., Liang, S., Fagan, S., and Leibowitz, S.F. (2012). Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption. Brain Res 1470, 24-34. doi: 10.1016/j.brainres.2012.06.004.
    • (2012) Brain Res , vol.1470 , pp. 24-34
    • Morganstern, I.1    Ye, Z.2    Liang, S.3    Fagan, S.4    Leibowitz, S.F.5
  • 95
    • 62849098571 scopus 로고    scopus 로고
    • Alzheimer-type neuropathological changes in morbidly obese elderly individuals
    • Mrak, R.E. (2009). Alzheimer-type neuropathological changes in morbidly obese elderly individuals. Clinical Neuropathology 28, 40-45.
    • (2009) Clinical Neuropathology , vol.28 , pp. 40-45
    • Mrak, R.E.1
  • 96
    • 72749106820 scopus 로고    scopus 로고
    • Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding
    • Murray, A.J., Knight, N.S., Cochlin, L.E., Mcaleese, S., Deacon, R.M., Rawlins, J.N., and Clarke, K. (2009). Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding. Faseb J 23, 4353-4360.
    • (2009) Faseb J , vol.23 , pp. 4353-4360
    • Murray, A.J.1    Knight, N.S.2    Cochlin, L.E.3    Mcaleese, S.4    Deacon, R.M.5    Rawlins, J.N.6    Clarke, K.7
  • 97
    • 0030681215 scopus 로고    scopus 로고
    • Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease.
    • National Institute on Aging, A.R.I.W.G. (1997). Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Neurobiol Aging 18, S1-2.
    • (1997) Neurobiol Aging , vol.18 , pp. S1-S2
  • 98
    • 84872166765 scopus 로고    scopus 로고
    • Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
    • Odegaard, J.I., and Chawla, A. (2013). Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science 339, 172-177. doi: 10.1126/science.1230721.
    • (2013) Science , vol.339 , pp. 172-177
    • Odegaard, J.I.1    Chawla, A.2
  • 99
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • Ouchi, N., Parker, J.L., Lugus, J.J., and Walsh, K. (2011). Adipokines in inflammation and metabolic disease. Nat Rev Immunol 11, 85-97. doi: 10.1038/nri2921.
    • (2011) Nat Rev Immunol , vol.11 , pp. 85-97
    • Ouchi, N.1    Parker, J.L.2    Lugus, J.J.3    Walsh, K.4
  • 100
    • 84862111274 scopus 로고    scopus 로고
    • Bidirectional Association Between Depression and Metabolic Syndrome A systematic review and meta-analysis of epidemiological studies
    • Pan, A., Keum, N., Okereke, O.I., Sun, Q., Kivimaki, M., Rubin, R.R., and Hu, F.B. (2012). Bidirectional Association Between Depression and Metabolic Syndrome A systematic review and meta-analysis of epidemiological studies. Diabetes Care 35, 1171-1180. doi: Doi 10.2337/Dc11-2055.
    • (2012) Diabetes Care , vol.35 , pp. 1171-1180
    • Pan, A.1    Keum, N.2    Okereke, O.I.3    Sun, Q.4    Kivimaki, M.5    Rubin, R.R.6    Hu, F.B.7
  • 101
    • 33745456661 scopus 로고    scopus 로고
    • Brain abnormalities in human obesity: a voxel-based morphometric study
    • Pannacciulli, N., Del Parigi, A., Chen, K., Le, D.S., Reiman, E.M., and Tataranni, P.A. (2006). Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage 31, 1419-1425. doi: 10.1016/j.neuroimage.2006.01.047.
    • (2006) Neuroimage , vol.31 , pp. 1419-1425
    • Pannacciulli, N.1    Del Parigi, A.2    Chen, K.3    Le, D.S.4    Reiman, E.M.5    Tataranni, P.A.6
  • 103
    • 70350266822 scopus 로고    scopus 로고
    • Changes in hypothalamically mediated acute-phase inflammatory responses to lipopolysaccharide in diet-induced obese rats
    • Pohl, J., Woodside, B., and Luheshi, G.N. (2009). Changes in hypothalamically mediated acute-phase inflammatory responses to lipopolysaccharide in diet-induced obese rats. Endocrinology 150, 4901-4910. doi: 10.1210/en.2009-0526.
    • (2009) Endocrinology , vol.150 , pp. 4901-4910
    • Pohl, J.1    Woodside, B.2    Luheshi, G.N.3
  • 104
    • 84856021238 scopus 로고    scopus 로고
    • Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity
    • Puig, K.L., Floden, A.M., Adhikari, R., Golovko, M.Y., and Combs, C.K. (2012). Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity. Plos One 7. doi: ARTN e30378 DOI 10.1371/journal.pone.0030378.
    • (2012) Plos One , vol.7
    • Puig, K.L.1    Floden, A.M.2    Adhikari, R.3    Golovko, M.Y.4    Combs, C.K.5
  • 105
  • 107
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment- -pharmacological mechanisms
    • Reynolds, G.P., and Kirk, S.L. (2010). Metabolic side effects of antipsychotic drug treatment- -pharmacological mechanisms. Pharmacol Ther 125, 169-179. doi: 10.1016/j.pharmthera.2009.10.010.
    • (2010) Pharmacol Ther , vol.125 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 109
    • 68149101186 scopus 로고    scopus 로고
    • Health behaviors from early to late midlife as predictors of cognitive function: The Whitehall II study
    • Sabia, S., Nabi, H., Kivimaki, M., Shipley, M.J., Marmot, M.G., and Singh-Manoux, A. (2009). Health behaviors from early to late midlife as predictors of cognitive function: The Whitehall II study. Am J Epidemiol 170, 428-437. doi: 10.1093/aje/kwp161.
    • (2009) Am J Epidemiol , vol.170 , pp. 428-437
    • Sabia, S.1    Nabi, H.2    Kivimaki, M.3    Shipley, M.J.4    Marmot, M.G.5    Singh-Manoux, A.6
  • 111
    • 78149305142 scopus 로고    scopus 로고
    • Antidepressants and body weight: a comprehensive review and meta-analysis
    • Serretti, A., and Mandelli, L. (2010). Antidepressants and body weight: a comprehensive review and meta-analysis. J Clin Psychiatry 71, 1259-1272. doi: 10.4088/JCP.09r05346blu.
    • (2010) J Clin Psychiatry , vol.71 , pp. 1259-1272
    • Serretti, A.1    Mandelli, L.2
  • 112
    • 0035893251 scopus 로고    scopus 로고
    • Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity
    • Shanley, L.J., Irving, A.J., and Harvey, J. (2001). Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. Journal of Neuroscience 21, art. no.- RC186.
    • (2001) Journal of Neuroscience , vol.21
    • Shanley, L.J.1    Irving, A.J.2    Harvey, J.3
  • 113
    • 0031922362 scopus 로고    scopus 로고
    • A population study on blood-brain barrier function in 85- year-olds: relation to Alzheimer's disease and vascular dementia
    • Skoog, I., Wallin, A., Fredman, P., Hesse, C., Aevarsson, O., Karlsson, I., Gottfries, C.G., and Blennow, K. (1998). A population study on blood-brain barrier function in 85- year-olds: relation to Alzheimer's disease and vascular dementia. Neurology 50, 966- 971.
    • (1998) Neurology , vol.50 , pp. 966-971
    • Skoog, I.1    Wallin, A.2    Fredman, P.3    Hesse, C.4    Aevarsson, O.5    Karlsson, I.6    Gottfries, C.G.7    Blennow, K.8
  • 114
    • 77649189116 scopus 로고    scopus 로고
    • Astrocytes: biology and pathology
    • Sofroniew, M.V., and Vinters, H.V. (2010). Astrocytes: biology and pathology. Acta Neuropathologica 119, 7-35. doi: DOI 10.1007/s00401-009-0619-8.
    • (2010) Acta Neuropathologica , vol.119 , pp. 7-35
    • Sofroniew, M.V.1    Vinters, H.V.2
  • 116
  • 117
    • 12144268588 scopus 로고    scopus 로고
    • A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study
    • Stewart, R., Masaki, K., Xue, Q.L., Peila, R., Petrovitch, H., White, L.R., and Launer, L.J. (2005). A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol 62, 55-60. doi: 10.1001/archneur.62.1.55.
    • (2005) Arch Neurol , vol.62 , pp. 55-60
    • Stewart, R.1    Masaki, K.2    Xue, Q.L.3    Peila, R.4    Petrovitch, H.5    White, L.R.6    Launer, L.J.7
  • 118
    • 55549139200 scopus 로고    scopus 로고
    • Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
    • Stranahan, A.M., Norman, E.D., Lee, K., Cutler, R.G., Telljohann, R.S., Egan, J.M., and Mattson, M.P. (2008). Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. Hippocampus 18, 1085-1088. doi: 10.1002/hipo.20470.
    • (2008) Hippocampus , vol.18 , pp. 1085-1088
    • Stranahan, A.M.1    Norman, E.D.2    Lee, K.3    Cutler, R.G.4    Telljohann, R.S.5    Egan, J.M.6    Mattson, M.P.7
  • 119
    • 0033528254 scopus 로고    scopus 로고
    • Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage
    • Su, G.C., Arendash, G.W., Kalaria, R.N., Bjugstad, K.B., and Mullan, M. (1999). Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage. Brain Res 818, 105-117.
    • (1999) Brain Res , vol.818 , pp. 105-117
    • Su, G.C.1    Arendash, G.W.2    Kalaria, R.N.3    Bjugstad, K.B.4    Mullan, M.5
  • 121
    • 39449125017 scopus 로고    scopus 로고
    • Relationship between body mass index and gray matter volume in 1,428 healthy individuals
    • Taki, Y., Kinomura, S., Sato, K., Inoue, K., Goto, R., Okada, K., Uchida, S., Kawashima, R., and Fukuda, H. (2008). Relationship between body mass index and gray matter volume in 1,428 healthy individuals. Obesity 16, 119-124. doi: Doi 10.1038/Oby.2007.4.
    • (2008) Obesity , vol.16 , pp. 119-124
    • Taki, Y.1    Kinomura, S.2    Sato, K.3    Inoue, K.4    Goto, R.5    Okada, K.6    Uchida, S.7    Kawashima, R.8    Fukuda, H.9
  • 123
    • 45249117903 scopus 로고    scopus 로고
    • High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
    • JNC5415
    • Thirumangalakudi, L., Prakasam, A., Zhang, R., Bimonte-Nelson, H., Sambamurti, K., Kindy, M.S., and Bhat, N.R. (2008). High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J Neurochem 106, 475-485. doi: JNC5415 [pii]10.1111/j.1471-4159.2008.05415.x.
    • (2008) J Neurochem , vol.106 , pp. 475-485
    • Thirumangalakudi, L.1    Prakasam, A.2    Zhang, R.3    Bimonte-Nelson, H.4    Sambamurti, K.5    Kindy, M.S.6    Bhat, N.R.7
  • 126
    • 84908376800 scopus 로고    scopus 로고
    • Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in Beta-amyloid generation and Alzheimer's disease
    • Tucsek, Z., Toth, P., Sosnowska, D., Gautam, T., Mitschelen, M., Koller, A., Szalai, G., Sonntag, W.E., Ungvari, Z., and Csiszar, A. (2014a). Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in Beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci 69, 1212-1226. doi: 10.1093/gerona/glt177.
    • (2014) J Gerontol A Biol Sci Med Sci , vol.69 , pp. 1212-1226
    • Tucsek, Z.1    Toth, P.2    Sosnowska, D.3    Gautam, T.4    Mitschelen, M.5    Koller, A.6    Szalai, G.7    Sonntag, W.E.8    Ungvari, Z.9    Csiszar, A.10
  • 128
    • 74949113952 scopus 로고    scopus 로고
    • A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adult mouse brain
    • Valente, T., Hidalgo, J., Bolea, I., Ramirez, B., Angles, N., Reguant, J., Morello, J.R., Gutierrez, C., Boada, M., and Unzeta, M. (2009). A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adult mouse brain. J Alzheimers Dis 18, 849-865. doi: 10.3233/JAD-2009-1188.
    • (2009) J Alzheimers Dis , vol.18 , pp. 849-865
    • Valente, T.1    Hidalgo, J.2    Bolea, I.3    Ramirez, B.4    Angles, N.5    Reguant, J.6    Morello, J.R.7    Gutierrez, C.8    Boada, M.9    Unzeta, M.10
  • 129
    • 0033537013 scopus 로고    scopus 로고
    • Elevated C-reactive protein levels in overweight and obese adults
    • Visser, M., Bouter, L.M., Mcquillan, G.M., Wener, M.H., and Harris, T.B. (1999). Elevated C-reactive protein levels in overweight and obese adults. Jama 282, 2131-2135.
    • (1999) Jama , vol.282 , pp. 2131-2135
    • Visser, M.1    Bouter, L.M.2    Mcquillan, G.M.3    Wener, M.H.4    Harris, T.B.5
  • 130
    • 24644500799 scopus 로고    scopus 로고
    • The impact of obesity on psychological well-being
    • Wardle, J., and Cooke, L. (2005). The impact of obesity on psychological well-being. Best Pract Res Clin Endocrinol Metab 19, 421-440. doi: 10.1016/j.beem.2005.04.006.
    • (2005) Best Pract Res Clin Endocrinol Metab , vol.19 , pp. 421-440
    • Wardle, J.1    Cooke, L.2
  • 132
    • 20544462061 scopus 로고    scopus 로고
    • Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study
    • Whitmer, R.A., Gunderson, E.P., Barrett-Connor, E., Quesenberry, C.P., Jr., and Yaffe, K. (2005). Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. Bmj 330, 1360.
    • (2005) Bmj , vol.330 , pp. 1360
    • Whitmer, R.A.1    Gunderson, E.P.2    Barrett-Connor, E.3    Quesenberry Jr, C.P.4    Yaffe, K.5
  • 134
    • 0012850301 scopus 로고    scopus 로고
    • A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor
    • Wu, A., Molteni, R., Ying, Z., and Gomez-Pinilla, F. (2003). A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience 119, 365-375.
    • (2003) Neuroscience , vol.119 , pp. 365-375
    • Wu, A.1    Molteni, R.2    Ying, Z.3    Gomez-Pinilla, F.4
  • 136
    • 84867144608 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome and functional and structural brain impairments in adolescence
    • Yau, P.L., Castro, M.G., Tagani, A., Tsui, W.H., and Convit, A. (2012). Obesity and metabolic syndrome and functional and structural brain impairments in adolescence. Pediatrics 130, e856-864. doi: 10.1542/peds.2012-0324.
    • (2012) Pediatrics , vol.130 , pp. e856-864
    • Yau, P.L.1    Castro, M.G.2    Tagani, A.3    Tsui, W.H.4    Convit, A.5
  • 137
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?
    • Yudkin, J.S., Stehouwer, C.D., Emeis, J.J., and Coppack, S.W. (1999). C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 19, 972-978.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.2    Emeis, J.J.3    Coppack, S.W.4
  • 138
    • 67349254152 scopus 로고    scopus 로고
    • Exacerbation of Poststroke Dementia by Type 2 Diabetes Is Associated with Synergistic Increases of Beta-Secretase Activation and Beta-Amyloid Generation in Rat Brains
    • Zhang, T., Pan, B.S., Zhao, B., Zhang, L.M., Huang, Y.L., and Sun, F.Y. (2009). Exacerbation of Poststroke Dementia by Type 2 Diabetes Is Associated with Synergistic Increases of Beta-Secretase Activation and Beta-Amyloid Generation in Rat Brains. Neuroscience 161, 1045-1056. doi: DOI 10.1016/j.neuroscience.2009.04.032.
    • (2009) Neuroscience , vol.161 , pp. 1045-1056
    • Zhang, T.1    Pan, B.S.2    Zhao, B.3    Zhang, L.M.4    Huang, Y.L.5    Sun, F.Y.6
  • 139
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic, B.V. (2011). Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 12, 723-738. doi: 10.1038/nrn3114.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1


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