메뉴 건너뛰기




Volumn 50, Issue 4, 1998, Pages 966-971

A population study on blood-brain barrier function in 85-year-olds: Relation to Alzheimer's disease and vascular dementia

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; APOLIPOPROTEIN E3;

EID: 0031922362     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.50.4.966     Document Type: Article
Times cited : (216)

References (63)
  • 1
    • 0023869451 scopus 로고
    • Effect of aging on the blood-brain barrier
    • Review
    • Mooradian A. Effect of aging on the blood-brain barrier. Neurobiol Aging 1988:9:31-39. Review.
    • (1988) Neurobiol Aging , vol.9 , pp. 31-39
    • Mooradian, A.1
  • 2
    • 0002052091 scopus 로고
    • Cerebrospinal fluid as reflection of internal milieu of brain
    • Wood JH, ed. New York: Plenum
    • Milhorat T, Hammock K. Cerebrospinal fluid as reflection of internal milieu of brain. In: Wood JH, ed. Neurobiology of cerebrospinal fluid. New York: Plenum, 1983:1-23.
    • (1983) Neurobiology of Cerebrospinal Fluid , pp. 1-23
    • Milhorat, T.1    Hammock, K.2
  • 3
    • 0018841902 scopus 로고
    • Multiple sclerosis: Measurement and validation of central nervous system IgG synthesis rate
    • Tourtellotte WW, Potvin AR, Fleming JO, et al. Multiple sclerosis: measurement and validation of central nervous system IgG synthesis rate. Neurology 1980;30:240-244.
    • (1980) Neurology , vol.30 , pp. 240-244
    • Tourtellotte, W.W.1    Potvin, A.R.2    Fleming, J.O.3
  • 5
    • 0028037604 scopus 로고
    • Cerebrospinal fluid in the diagnosis of multiple sclerosis: A consensus report
    • Andersson M, Alvarez-Cermeno J, Bernardi G, et al. Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report. J Neurol Neurosurg Psychiatry 1994;57:897-902.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 897-902
    • Andersson, M.1    Alvarez-Cermeno, J.2    Bernardi, G.3
  • 6
    • 0027503277 scopus 로고
    • Protein analysis in cerebrospinal fluid. II. Reference values derived from healthy individuals 18-88 years of age
    • Blennow K, Wallin A, Gottfries CG, et al. Protein analysis in cerebrospinal fluid. II. Reference values derived from healthy individuals 18-88 years of age. Eur Neurol 1993;33:129-133.
    • (1993) Eur Neurol , vol.33 , pp. 129-133
    • Blennow, K.1    Wallin, A.2    Gottfries, C.G.3
  • 8
    • 0030467118 scopus 로고    scopus 로고
    • Fundamental pathological lesions in vascular dementia
    • Olsson Y, Brun A, Englund E. Fundamental pathological lesions in vascular dementia. Acta Neurol Scand 1996;168(suppl 2):31-38.
    • (1996) Acta Neurol Scand , vol.168 , Issue.2 SUPPL. , pp. 31-38
    • Olsson, Y.1    Brun, A.2    Englund, E.3
  • 9
    • 0028287502 scopus 로고
    • Pathogenesis of vascular dementia: The possible role of hypertension
    • Johansson BB. Pathogenesis of vascular dementia: the possible role of hypertension. Dementia 1994;5:174-176.
    • (1994) Dementia , vol.5 , pp. 174-176
    • Johansson, B.B.1
  • 10
    • 0021750083 scopus 로고
    • Cerebral vascular bed in hyeprtension and consequences for the brain
    • Johansson BB. Cerebral vascular bed in hyeprtension and consequences for the brain. Hypertension 1984;6(suppl 3):81-86.
    • (1984) Hypertension , vol.6 , Issue.3 SUPPL. , pp. 81-86
    • Johansson, B.B.1
  • 11
    • 0028848312 scopus 로고
    • Evidence of blood-cerebrospinal fluid-barrier impairment in a subgroup of patients with dementia of the Alzheimer type and major depression: A possible indicator for immunoactivation
    • Hampel H, Muller-Spahn F, Berger C, Haberl A, Ackenheil M, Hock C. Evidence of blood-cerebrospinal fluid-barrier impairment in a subgroup of patients with dementia of the Alzheimer type and major depression: a possible indicator for immunoactivation. Dementia 1995;6:348-354.
    • (1995) Dementia , vol.6 , pp. 348-354
    • Hampel, H.1    Muller-Spahn, F.2    Berger, C.3    Haberl, A.4    Ackenheil, M.5    Hock, C.6
  • 12
    • 0025870546 scopus 로고
    • Blood brain barrier in a geriatric population: Barrier function in degenerative and vascular dementia
    • Mecocci P, Parnetti L, Reboldi GP, et al. Blood brain barrier in a geriatric population: barrier function in degenerative and vascular dementia. Acta Neurol Scand 1991;84:210-213.
    • (1991) Acta Neurol Scand , vol.84 , pp. 210-213
    • Mecocci, P.1    Parnetti, L.2    Reboldi, G.P.3
  • 14
    • 0025978236 scopus 로고
    • White-matter lesions on CT in Alzheimer patients: Relation to clinical symptomatology and vascular factors
    • Blennow K, Wallin A, Uhlemann C, Gottfries C. White-matter lesions on CT in Alzheimer patients: relation to clinical symptomatology and vascular factors. Acta Neurol Scand 1991;83: 187-193.
    • (1991) Acta Neurol Scand , vol.83 , pp. 187-193
    • Blennow, K.1    Wallin, A.2    Uhlemann, C.3    Gottfries, C.4
  • 15
    • 0027402238 scopus 로고
    • Cerebrospinal fluid proteins in patients with leucoaraiosis: Possible abnormalities in blood-brain barrier function
    • Pantoni L, Inzitari D, Pracucci G, et al. Cerebrospinal fluid proteins in patients with leucoaraiosis: possible abnormalities in blood-brain barrier function. J Neurol Sci 1993;115:125-131.
    • (1993) J Neurol Sci , vol.115 , pp. 125-131
    • Pantoni, L.1    Inzitari, D.2    Pracucci, G.3
  • 16
    • 0002866684 scopus 로고
    • The neuropathology of Alzheimer's disease
    • Burns A, Levy R, eds. London: Chapman and Hall
    • Lantos PL, Cairns NJ. The neuropathology of Alzheimer's disease. In: Burns A, Levy R, eds. Dementia. London: Chapman and Hall, 1994:185-207.
    • (1994) Dementia , pp. 185-207
    • Lantos, P.L.1    Cairns, N.J.2
  • 17
    • 0030603535 scopus 로고    scopus 로고
    • A 15-year longitudinal study on blood pressure and dementia
    • Skoog I, Lernfelt B, Landahl S, et al. A 15-year longitudinal study on blood pressure and dementia. Lancet 1996;347:1141-1145.
    • (1996) Lancet , vol.347 , pp. 1141-1145
    • Skoog, I.1    Lernfelt, B.2    Landahl, S.3
  • 18
    • 0029020269 scopus 로고
    • Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension
    • Sparks DL, Scheff SW, Liu H, Landers TM, Coyne CM, Hunsaker JC III. Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension. J Neurol Sci 1995;131:162-169.
    • (1995) J Neurol Sci , vol.131 , pp. 162-169
    • Sparks, D.L.1    Scheff, S.W.2    Liu, H.3    Landers, T.M.4    Coyne, C.M.5    Hunsaker J.C. III6
  • 20
    • 0031026879 scopus 로고    scopus 로고
    • Atherosclerosis, apolipoprotein E, and the prevalence of dementia and Alzheimer's disease in the Rotterdam Study
    • Hofman A, Ott A, Breteler MMB, et al. Atherosclerosis, apolipoprotein E, and the prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet 1997;349:151-154.
    • (1997) Lancet , vol.349 , pp. 151-154
    • Hofman, A.1    Ott, A.2    Breteler, M.M.B.3
  • 21
    • 0022572209 scopus 로고
    • A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study
    • Brun A, Englund E. A white matter disorder in dementia of the Alzheimer type: a pathoanatomical study. Ann Neurol 1986;19:253-262.
    • (1986) Ann Neurol , vol.19 , pp. 253-262
    • Brun, A.1    Englund, E.2
  • 22
    • 0024405528 scopus 로고
    • Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease
    • De la Monte SM. Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease. Ann Neurol 1989;25: 450-459.
    • (1989) Ann Neurol , vol.25 , pp. 450-459
    • De La Monte, S.M.1
  • 23
    • 0028277531 scopus 로고
    • The prevalence of white matter lesions on computed tomography of the brain in demented and non-demented 85-year-olds
    • Skoog I, Palmertz B, Andreasson L-A. The prevalence of white matter lesions on computed tomography of the brain in demented and non-demented 85-year-olds. J Geriatr Psychiatry Neurol 1994;7:169-175.
    • (1994) J Geriatr Psychiatry Neurol , vol.7 , pp. 169-175
    • Skoog, I.1    Palmertz, B.2    Andreasson, L.-A.3
  • 24
    • 0018610797 scopus 로고
    • Congophilic microangiopathy in the pathogenesis of Alzheimer's syndrome (presenile dementia)
    • Glenner GG. Congophilic microangiopathy in the pathogenesis of Alzheimer's syndrome (presenile dementia). Med Hypoth 1979:5:1231-1236.
    • (1979) Med Hypoth , vol.5 , pp. 1231-1236
    • Glenner, G.G.1
  • 25
    • 0023254674 scopus 로고
    • Cerebral amyloid angiopathy: A critical review
    • Vinters HV. Cerebral amyloid angiopathy: a critical review. Stroke 1987;18:311-324.
    • (1987) Stroke , vol.18 , pp. 311-324
    • Vinters, H.V.1
  • 26
    • 0029896438 scopus 로고    scopus 로고
    • β-Amyloid vasoactivity in Alzheimer's disease
    • Letter
    • Kalaria RN, Hedera P. β-Amyloid vasoactivity in Alzheimer's disease. Lancet 1996;347:1492-1493. Letter.
    • (1996) Lancet , vol.347 , pp. 1492-1493
    • Kalaria, R.N.1    Hedera, P.2
  • 27
    • 0025341743 scopus 로고
    • Microangiopathy, the vascular basement membrane and Alzheimer's disease: A review
    • Perlmutter LS, Chui HC. Microangiopathy, the vascular basement membrane and Alzheimer's disease: a review. Brain Res Bull 1990;24:677-686.
    • (1990) Brain Res Bull , vol.24 , pp. 677-686
    • Perlmutter, L.S.1    Chui, H.C.2
  • 28
    • 0026066312 scopus 로고
    • Observations of microvessels in the brain with Alzheimer's disease by scanning electron microscopy
    • Kimura T, Hashimura T, Miyakawa T. Observations of microvessels in the brain with Alzheimer's disease by scanning electron microscopy. Jpn J Psych Neurol 1991;45:671-676.
    • (1991) Jpn J Psych Neurol , vol.45 , pp. 671-676
    • Kimura, T.1    Hashimura, T.2    Miyakawa, T.3
  • 29
    • 0023475838 scopus 로고
    • Denervation microangiopathy in senile dementia, Alzheimer type
    • Scheibel AB, Duong T, Tomiyasu U. Denervation microangiopathy in senile dementia, Alzheimer type. Alz Dis Assoc Dis 1987;1:19-37.
    • (1987) Alz Dis Assoc Dis , vol.1 , pp. 19-37
    • Scheibel, A.B.1    Duong, T.2    Tomiyasu, U.3
  • 30
    • 0029655250 scopus 로고    scopus 로고
    • Utrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients
    • Claudio L. Utrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients. Acta Neuropathol 1996;91:6-14.
    • (1996) Acta Neuropathol , vol.91 , pp. 6-14
    • Claudio, L.1
  • 31
    • 0020348267 scopus 로고
    • Evidence for blood-brain barrier changes in senile dementia of the Alzheimer type (SDAT)
    • Wisniewski HM, Kozlowski PB. Evidence for blood-brain barrier changes in senile dementia of the Alzheimer type (SDAT). Ann NY Acad Sci 1982;396:119-131.
    • (1982) Ann NY Acad Sci , vol.396 , pp. 119-131
    • Wisniewski, H.M.1    Kozlowski, P.B.2
  • 32
    • 0020715072 scopus 로고
    • Alzheimer's disease and senile brains: An immunofluorescence study
    • Licandro A, Ferla S, Tavolato B. Alzheimer's disease and senile brains: an immunofluorescence study. Riv Pat Nerv Ment 1983;104:75-87.
    • (1983) Riv Pat Nerv Ment , vol.104 , pp. 75-87
    • Licandro, A.1    Ferla, S.2    Tavolato, B.3
  • 34
    • 0022921664 scopus 로고
    • An integrative hypothesis concerning the pathogenesis and progression of Alzheimer's disease
    • Hardy J, Mann D, Wester P, Winblad B. An integrative hypothesis concerning the pathogenesis and progression of Alzheimer's disease. Neurobiol Aging 1986;7:489-502.
    • (1986) Neurobiol Aging , vol.7 , pp. 489-502
    • Hardy, J.1    Mann, D.2    Wester, P.3    Winblad, B.4
  • 35
    • 0026377774 scopus 로고
    • Serum amyloid P in Alzheimer's disease. Implications for dysfunction of the blood-brain barrier
    • Kalaria RN, Golde TE, Cohen ML, Younkin SG. Serum amyloid P in Alzheimer's disease. Implications for dysfunction of the blood-brain barrier. Ann NY Acad Sci 1991;640:145-148.
    • (1991) Ann NY Acad Sci , vol.640 , pp. 145-148
    • Kalaria, R.N.1    Golde, T.E.2    Cohen, M.L.3    Younkin, S.G.4
  • 36
    • 0028284580 scopus 로고
    • Vascular basement membrane components and the lesions of Alzheimer's disease: Light and electron microscopic analyses
    • Perlmutter LS, Myers MA, Barrón E. Vascular basement membrane components and the lesions of Alzheimer's disease: light and electron microscopic analyses. Microsc Res Technique 1994;28:204-215.
    • (1994) Microsc Res Technique , vol.28 , pp. 204-215
    • Perlmutter, L.S.1    Myers, M.A.2    Barrón, E.3
  • 37
    • 0021854780 scopus 로고
    • CSF in Alzheimer's disease. Studies on blood-brain barrier function and intrathecal protein synthesis
    • Elovaara I, Icén A, Palo J, Erkinjuntti T. CSF in Alzheimer's disease. Studies on blood-brain barrier function and intrathecal protein synthesis. J Neurol Sci 1985:70:73-80.
    • (1985) J Neurol Sci , vol.70 , pp. 73-80
    • Elovaara, I.1    Icén, A.2    Palo, J.3    Erkinjuntti, T.4
  • 38
    • 0023950591 scopus 로고
    • Oligoclonal immunoglobulin bands in cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia
    • Elovaara I, Seppälä I, Palo J, Sulkava R, Erkinjuntti T. Oligoclonal immunoglobulin bands in cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia. Acta Neurol Scand 1988:77:397-401.
    • (1988) Acta Neurol Scand , vol.77 , pp. 397-401
    • Elovaara, I.1    Seppälä, I.2    Palo, J.3    Sulkava, R.4    Erkinjuntti, T.5
  • 40
    • 0023110541 scopus 로고
    • CSF and serum concentration of albumin and IgG in Alzheimer's disease
    • Kay A, May C, Papadopoulos N, et al. CSF and serum concentration of albumin and IgG in Alzheimer's disease. Neurobiol Aging 1987:8:21-25.
    • (1987) Neurobiol Aging , vol.8 , pp. 21-25
    • Kay, A.1    May, C.2    Papadopoulos, N.3
  • 41
    • 0021986721 scopus 로고
    • The integrity of the blood-brain barrier in Alzheimer's type and multi-infarct dementia evaluated by the study of albumin and IgG in serum and cerebrospinal fluid
    • Leonardi A, Gandolfo C, Caponetto C, Arata L, Vecchia R. The integrity of the blood-brain barrier in Alzheimer's type and multi-infarct dementia evaluated by the study of albumin and IgG in serum and cerebrospinal fluid. J Neurol Sci 1985;67: 253-261.
    • (1985) J Neurol Sci , vol.67 , pp. 253-261
    • Leonardi, A.1    Gandolfo, C.2    Caponetto, C.3    Arata, L.4    Vecchia, R.5
  • 43
    • 0016820254 scopus 로고
    • Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. I. General presentation of the study
    • Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. I. General presentation of the study. Acta Med Scand 1975;198:397-407.
    • (1975) Acta Med Scand , vol.198 , pp. 397-407
    • Rinder, L.1    Roupe, S.2    Steen, B.3    Svanborg, A.4
  • 44
    • 0017635810 scopus 로고
    • Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. II. General presentation of social and medical conditions
    • Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. II. General presentation of social and medical conditions. Acta Med Scand 1977;611(suppl 2):3-37.
    • (1977) Acta Med Scand , vol.611 , Issue.2 SUPPL. , pp. 3-37
    • Svanborg, A.1
  • 45
    • 0029797820 scopus 로고    scopus 로고
    • A population-based study on the incidence of dementia disorders between 85 and 88 years of age
    • Aevarsson O, Skoog I. A population-based study on the incidence of dementia disorders between 85 and 88 years of age. J Am Geriatr Soc 1996;44:1455-1460.
    • (1996) J Am Geriatr Soc , vol.44 , pp. 1455-1460
    • Aevarsson, O.1    Skoog, I.2
  • 47
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 48
    • 0027534657 scopus 로고
    • Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN international workshop
    • Román GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN international workshop. Neurology 1993;43: 250-260.
    • (1993) Neurology , vol.43 , pp. 250-260
    • Román, G.C.1    Tatemichi, T.K.2    Erkinjuntti, T.3
  • 49
    • 0015275825 scopus 로고
    • Electroimmunoassay
    • Laurell CB. Electroimmunoassay. Scand J Clin Lab Invest 1972:29(suppl 124):21-37.
    • (1972) Scand J Clin Lab Invest , vol.29 , Issue.124 SUPPL. , pp. 21-37
    • Laurell, C.B.1
  • 50
    • 0017574898 scopus 로고
    • Principles of albumin and IgG analyses in neurological disorders. II. Relation of the concentration of the proteins in serum and cerebrospinal fluid
    • Link H, Tibbling G. Principles of albumin and IgG analyses in neurological disorders. II. Relation of the concentration of the proteins in serum and cerebrospinal fluid. Scand J Clin Lab Invest 1977:37:391-396.
    • (1977) Scand J Clin Lab Invest , vol.37 , pp. 391-396
    • Link, H.1    Tibbling, G.2
  • 51
    • 0022460597 scopus 로고
    • A method for the identification of apolipoprotein e isoforms employing chemical precipitation and flat bed isoelectric focusing in agarose
    • Kane JW, Gowland G. A method for the identification of apolipoprotein E isoforms employing chemical precipitation and flat bed isoelectric focusing in agarose. Ann Clin Biochem 1986;23:509-513.
    • (1986) Ann Clin Biochem , vol.23 , pp. 509-513
    • Kane, J.W.1    Gowland, G.2
  • 54
    • 0019993831 scopus 로고
    • Immunoglobulins and complement factors in senile plaques
    • Berlin
    • Eikelenboom P, Stam FC. Immunoglobulins and complement factors in senile plaques. Acta Neuropathol (Berlin) 1982:57: 239-242.
    • (1982) Acta Neuropathol , vol.57 , pp. 239-242
    • Eikelenboom, P.1    Stam, F.C.2
  • 55
    • 0029910943 scopus 로고    scopus 로고
    • Complement activation in the central nervous system following blood-brain barrier damage in man
    • Lindsberg PJ, Öhman J, Lehto T, et al. Complement activation in the central nervous system following blood-brain barrier damage in man. Ann Neurol 1996;40:587-596.
    • (1996) Ann Neurol , vol.40 , pp. 587-596
    • Lindsberg, P.J.1    Öhman, J.2    Lehto, T.3
  • 56
    • 0021356005 scopus 로고
    • Cerebral changes in chronic hypertension: Combined permeability and immunohistochemical studies
    • Berlin
    • Nag S. Cerebral changes in chronic hypertension: combined permeability and immunohistochemical studies. Acta Neuropathol (Berlin) 1984;62:178-184.
    • (1984) Acta Neuropathol , vol.62 , pp. 178-184
    • Nag, S.1
  • 57
    • 0029670094 scopus 로고    scopus 로고
    • β-Amyloid-mediated vasoactivity and vascular endothelial damage
    • Thomas T, Thomas G, McLendon C, Sutton T, Mullan M. β-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996;380:168-171.
    • (1996) Nature , vol.380 , pp. 168-171
    • Thomas, T.1    Thomas, G.2    McLendon, C.3    Sutton, T.4    Mullan, M.5
  • 58
    • 0021273682 scopus 로고
    • The protective influence of the locus ceruleus on the blood-brain barrier
    • Harik SI, McGunigal T. The protective influence of the locus ceruleus on the blood-brain barrier. Ann Neurol 1984;15: 568-574.
    • (1984) Ann Neurol , vol.15 , pp. 568-574
    • Harik, S.I.1    McGunigal, T.2
  • 59
    • 0021911830 scopus 로고
    • CT contrast enhancement on brain scans and blood-CSF barrier disturbances in cerebral ischemic infarction
    • Hornig CR, Busse O, Buettner T, Dorndorf W, Agnoli A, Akengin Z. CT contrast enhancement on brain scans and blood-CSF barrier disturbances in cerebral ischemic infarction. Stroke 1985;16:268-273.
    • (1985) Stroke , vol.16 , pp. 268-273
    • Hornig, C.R.1    Busse, O.2    Buettner, T.3    Dorndorf, W.4    Agnoli, A.5    Akengin, Z.6
  • 61
    • 0029127716 scopus 로고
    • White matter lesions and disequilibrium in older people. II. Clinicopathologic correlation
    • Baloh RW, Vinters HV. White matter lesions and disequilibrium in older people. II. Clinicopathologic correlation. Arch Neurol 1995;52:975-981.
    • (1995) Arch Neurol , vol.52 , pp. 975-981
    • Baloh, R.W.1    Vinters, H.V.2
  • 62
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988;240:622-630.
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 63
    • 0029665096 scopus 로고    scopus 로고
    • Apolipoprotein E-∈4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • Premkumar DRD, Cohen DL, Hedera P, Friedland RP, Kalaria RN. Apolipoprotein E-∈4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol 1996;148:2083-2095.
    • (1996) Am J Pathol , vol.148 , pp. 2083-2095
    • Premkumar, D.R.D.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.