메뉴 건너뛰기




Volumn 6, Issue 9, 2011, Pages

Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; GLUCOSE; GLYCOPROTEIN GP 130; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; RESISTIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA;

EID: 80052838069     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024325     Document Type: Article
Times cited : (217)

References (89)
  • 1
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, et al. (2009) Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 120: 1640-1645.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5
  • 3
    • 79952276408 scopus 로고    scopus 로고
    • Metabolic syndrome: what are the risks for humans?
    • Gupta A, Gupta V, (2010) Metabolic syndrome: what are the risks for humans? Biosci Trends 4: 204-212.
    • (2010) Biosci Trends , vol.4 , pp. 204-212
    • Gupta, A.1    Gupta, V.2
  • 4
    • 72049129177 scopus 로고    scopus 로고
    • Metabolic syndrome and cognition in patients with manifest atherosclerotic disease: the SMART study
    • Muller M, van Raamt F, Visseren FL, Kalmijn S, Geerlings MI, et al. (2010) Metabolic syndrome and cognition in patients with manifest atherosclerotic disease: the SMART study. Neuroepidemiology 34: 83-89.
    • (2010) Neuroepidemiology , vol.34 , pp. 83-89
    • Muller, M.1    van Raamt, F.2    Visseren, F.L.3    Kalmijn, S.4    Geerlings, M.I.5
  • 5
    • 79951633727 scopus 로고    scopus 로고
    • Metabolic syndrome and cognitive decline in French elders: the Three-City Study
    • Raffaitin C, Feart C, Le Goff M, Amieva H, Helmer C, et al. (2011) Metabolic syndrome and cognitive decline in French elders: the Three-City Study. Neurology 76: 518-525.
    • (2011) Neurology , vol.76 , pp. 518-525
    • Raffaitin, C.1    Feart, C.2    Le Goff, M.3    Amieva, H.4    Helmer, C.5
  • 6
    • 77953089836 scopus 로고    scopus 로고
    • Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use
    • van Reedt Dortland AK, Giltay EJ, van Veen T, Zitman FG, Penninx BW, (2010) Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use. Acta Psychiatr Scand 122: 30-39.
    • (2010) Acta Psychiatr Scand , vol.122 , pp. 30-39
    • van Reedt Dortland, A.K.1    Giltay, E.J.2    van Veen, T.3    Zitman, F.G.4    Penninx, B.W.5
  • 7
    • 77957672120 scopus 로고    scopus 로고
    • Prevention of cardiovascular disease: obesity, diabetes and the metabolic syndrome
    • Padwal RS, Sharma AM, (2010) Prevention of cardiovascular disease: obesity, diabetes and the metabolic syndrome. Can J Cardiol 26 (Suppl C): 18C-20C.
    • (2010) Can J Cardiol , vol.26 , Issue.SUPPL. C
    • Padwal, R.S.1    Sharma, A.M.2
  • 8
    • 77951665029 scopus 로고    scopus 로고
    • Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys
    • Blalock EM, Grondin R, Chen KC, Thibault O, Thibault V, et al. (2010) Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys. J Neurosci 30: 6058-6071.
    • (2010) J Neurosci , vol.30 , pp. 6058-6071
    • Blalock, E.M.1    Grondin, R.2    Chen, K.C.3    Thibault, O.4    Thibault, V.5
  • 9
    • 33845570920 scopus 로고    scopus 로고
    • The role of depression and anxiety in onset of diabetes in a large population-based study
    • Engum A, (2007) The role of depression and anxiety in onset of diabetes in a large population-based study. J Psychosom Res 62: 31-38.
    • (2007) J Psychosom Res , vol.62 , pp. 31-38
    • Engum, A.1
  • 10
    • 68549088867 scopus 로고    scopus 로고
    • Lifetime history of major depression predicts the development of the metabolic syndrome in middle-aged women
    • Goldbacher EM, Bromberger J, Matthews KA, (2009) Lifetime history of major depression predicts the development of the metabolic syndrome in middle-aged women. Psychosom Med 71: 266-272.
    • (2009) Psychosom Med , vol.71 , pp. 266-272
    • Goldbacher, E.M.1    Bromberger, J.2    Matthews, K.A.3
  • 11
    • 77949455337 scopus 로고    scopus 로고
    • Metabolic syndrome, inflammation, and nonamnestic mild cognitive impairment in older persons: a population-based study
    • Roberts RO, Geda YE, Knopman DS, Cha RH, Boeve BF, et al. (2010) Metabolic syndrome, inflammation, and nonamnestic mild cognitive impairment in older persons: a population-based study. Alzheimer Dis Assoc Disord 24: 11-18.
    • (2010) Alzheimer Dis Assoc Disord , vol.24 , pp. 11-18
    • Roberts, R.O.1    Geda, Y.E.2    Knopman, D.S.3    Cha, R.H.4    Boeve, B.F.5
  • 12
    • 77952012895 scopus 로고    scopus 로고
    • Inflammatory biomarkers in 70 depressed inpatients with and without the metabolic syndrome
    • Zeugmann S, Quante A, Heuser I, Schwarzer R, Anghelescu I, (2010) Inflammatory biomarkers in 70 depressed inpatients with and without the metabolic syndrome. J Clin Psychiatry 71: 1007-1016.
    • (2010) J Clin Psychiatry , vol.71 , pp. 1007-1016
    • Zeugmann, S.1    Quante, A.2    Heuser, I.3    Schwarzer, R.4    Anghelescu, I.5
  • 13
    • 36849037934 scopus 로고    scopus 로고
    • Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being
    • Elenkov IJ, (2008) Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem Int 52: 40-51.
    • (2008) Neurochem Int , vol.52 , pp. 40-51
    • Elenkov, I.J.1
  • 14
    • 34347225636 scopus 로고    scopus 로고
    • Gastric bypass surgery is associated with reduced inflammation and less depression: a preliminary investigation
    • Emery CF, Fondow MD, Schneider CM, Christofi FL, Hunt C, et al. (2007) Gastric bypass surgery is associated with reduced inflammation and less depression: a preliminary investigation. Obes Surg 17: 759-763.
    • (2007) Obes Surg , vol.17 , pp. 759-763
    • Emery, C.F.1    Fondow, M.D.2    Schneider, C.M.3    Christofi, F.L.4    Hunt, C.5
  • 15
    • 59749102688 scopus 로고    scopus 로고
    • Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap
    • McIntyre RS, Rasgon NL, Kemp DE, Nguyen HT, Law CW, et al. (2009) Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap. Curr Diab Rep 9: 51-59.
    • (2009) Curr Diab Rep , vol.9 , pp. 51-59
    • McIntyre, R.S.1    Rasgon, N.L.2    Kemp, D.E.3    Nguyen, H.T.4    Law, C.W.5
  • 16
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R, (2005) Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111: 1448-1454.
    • (2005) Circulation , vol.111 , pp. 1448-1454
    • Dandona, P.1    Aljada, A.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5
  • 17
    • 78549245105 scopus 로고    scopus 로고
    • Systemic inflammation and the metabolic syndrome among middle-aged community volunteers
    • Marsland AL, McCaffery JM, Muldoon MF, Manuck SB, (2010) Systemic inflammation and the metabolic syndrome among middle-aged community volunteers. Metabolism 59: 1801-1808.
    • (2010) Metabolism , vol.59 , pp. 1801-1808
    • Marsland, A.L.1    McCaffery, J.M.2    Muldoon, M.F.3    Manuck, S.B.4
  • 18
    • 33748742519 scopus 로고    scopus 로고
    • Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue
    • Cancello R, Clement K, (2006) Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. Bjog 113: 1141-1147.
    • (2006) Bjog , vol.113 , pp. 1141-1147
    • Cancello, R.1    Clement, K.2
  • 20
    • 0142029561 scopus 로고    scopus 로고
    • Diabesity: an inflammatory metabolic condition
    • Schmidt MI, Duncan BB, (2003) Diabesity: an inflammatory metabolic condition. Clin Chem Lab Med 41: 1120-1130.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1120-1130
    • Schmidt, M.I.1    Duncan, B.B.2
  • 21
    • 42449095441 scopus 로고    scopus 로고
    • Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders
    • Anisman H, Merali Z, Hayley S, (2008) Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders. Prog Neurobiol 85: 1-74.
    • (2008) Prog Neurobiol , vol.85 , pp. 1-74
    • Anisman, H.1    Merali, Z.2    Hayley, S.3
  • 22
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW, (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9: 46-56.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 23
    • 23444451611 scopus 로고    scopus 로고
    • Mood disorders in the medically ill: scientific review and recommendations
    • Evans DL, Charney DS, Lewis L, Golden RN, Gorman JM, et al. (2005) Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry 58: 175-189.
    • (2005) Biol Psychiatry , vol.58 , pp. 175-189
    • Evans, D.L.1    Charney, D.S.2    Lewis, L.3    Golden, R.N.4    Gorman, J.M.5
  • 24
    • 50249114538 scopus 로고    scopus 로고
    • Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior
    • Moreau M, Andre C, O'Connor JC, Dumich SA, Woods JA, et al. (2008) Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior. Brain Behav Immun 22: 1087-1095.
    • (2008) Brain Behav Immun , vol.22 , pp. 1087-1095
    • Moreau, M.1    Andre, C.2    O'Connor, J.C.3    Dumich, S.A.4    Woods, J.A.5
  • 25
    • 65249156122 scopus 로고    scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin
    • O'Connor JC, Andre C, Wang Y, Lawson MA, Szegedi SS, et al. (2009) Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. J Neurosci 29: 4200-4209.
    • (2009) J Neurosci , vol.29 , pp. 4200-4209
    • O'Connor, J.C.1    Andre, C.2    Wang, Y.3    Lawson, M.A.4    Szegedi, S.S.5
  • 26
    • 64849115090 scopus 로고    scopus 로고
    • Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior
    • O'Connor JC, Lawson MA, Andre C, Briley EM, Szegedi SS, et al. (2009) Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior. J Immunol 182: 3202-3212.
    • (2009) J Immunol , vol.182 , pp. 3202-3212
    • O'Connor, J.C.1    Lawson, M.A.2    Andre, C.3    Briley, E.M.4    Szegedi, S.S.5
  • 27
    • 77950022119 scopus 로고    scopus 로고
    • CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression
    • Raison CL, Dantzer R, Kelley KW, Lawson MA, Woolwine BJ, et al. (2010) CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry 15: 393-403.
    • (2010) Mol Psychiatry , vol.15 , pp. 393-403
    • Raison, C.L.1    Dantzer, R.2    Kelley, K.W.3    Lawson, M.A.4    Woolwine, B.J.5
  • 28
    • 79959740393 scopus 로고    scopus 로고
    • Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms
    • Capuron L, Schroecksnadel S, Feart C, Aubert A, Higueret D, et al. (2011) Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms. Biol Psychiatry 70: 175-82.
    • (2011) Biol Psychiatry , vol.70 , pp. 175-182
    • Capuron, L.1    Schroecksnadel, S.2    Feart, C.3    Aubert, A.4    Higueret, D.5
  • 30
    • 33747160445 scopus 로고    scopus 로고
    • IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors
    • Chourbaji S, Urani A, Inta I, Sanchis-Segura C, Brandwein C, et al. (2006) IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors. Neurobiol Dis 23: 587-594.
    • (2006) Neurobiol Dis , vol.23 , pp. 587-594
    • Chourbaji, S.1    Urani, A.2    Inta, I.3    Sanchis-Segura, C.4    Brandwein, C.5
  • 31
    • 33750936288 scopus 로고    scopus 로고
    • Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers
    • Sparkman NL, Buchanan JB, Heyen JR, Chen J, Beverly JL, et al. (2006) Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers. J Neurosci 26: 10709-10716.
    • (2006) J Neurosci , vol.26 , pp. 10709-10716
    • Sparkman, N.L.1    Buchanan, J.B.2    Heyen, J.R.3    Chen, J.4    Beverly, J.L.5
  • 32
    • 33751332116 scopus 로고    scopus 로고
    • Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers
    • Marsland AL, Petersen KL, Sathanoori R, Muldoon MF, Neumann SA, et al. (2006) Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers. Psychosom Med 68: 895-903.
    • (2006) Psychosom Med , vol.68 , pp. 895-903
    • Marsland, A.L.1    Petersen, K.L.2    Sathanoori, R.3    Muldoon, M.F.4    Neumann, S.A.5
  • 33
    • 78149469093 scopus 로고    scopus 로고
    • Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships
    • O'Donovan A, Hughes BM, Slavich GM, Lynch L, Cronin MT, et al. (2010) Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships. Brain Behav Immun 24: 1074-1077.
    • (2010) Brain Behav Immun , vol.24 , pp. 1074-1077
    • O'Donovan, A.1    Hughes, B.M.2    Slavich, G.M.3    Lynch, L.4    Cronin, M.T.5
  • 34
    • 0037072285 scopus 로고    scopus 로고
    • Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging
    • Weaver JD, Huang MH, Albert M, Harris T, Rowe JW, et al. (2002) Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology 59: 371-378.
    • (2002) Neurology , vol.59 , pp. 371-378
    • Weaver, J.D.1    Huang, M.H.2    Albert, M.3    Harris, T.4    Rowe, J.W.5
  • 35
    • 50049113248 scopus 로고    scopus 로고
    • Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration
    • Andre C, O'Connor JC, Kelley KW, Lestage J, Dantzer R, et al. (2008) Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration. J Neuroimmunol 200: 90-99.
    • (2008) J Neuroimmunol , vol.200 , pp. 90-99
    • Andre, C.1    O'Connor, J.C.2    Kelley, K.W.3    Lestage, J.4    Dantzer, R.5
  • 37
    • 72649097241 scopus 로고    scopus 로고
    • Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice
    • Hein AM, Stasko MR, Matousek SB, Scott-McKean JJ, Maier SF, et al. (2010) Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav Immun 24: 243-253.
    • (2010) Brain Behav Immun , vol.24 , pp. 243-253
    • Hein, A.M.1    Stasko, M.R.2    Matousek, S.B.3    Scott-McKean, J.J.4    Maier, S.F.5
  • 38
    • 53349129897 scopus 로고    scopus 로고
    • Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
    • Lee JW, Lee YK, Yuk DY, Choi DY, Ban SB, et al. (2008) Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation. J Neuroinflammation 5: 37.
    • (2008) J Neuroinflammation , vol.5 , pp. 37
    • Lee, J.W.1    Lee, Y.K.2    Yuk, D.Y.3    Choi, D.Y.4    Ban, S.B.5
  • 39
    • 34548040464 scopus 로고    scopus 로고
    • Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice
    • Noble F, Rubira E, Boulanouar M, Palmier B, Plotkine M, et al. (2007) Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice. Neurosci Lett 424: 106-110.
    • (2007) Neurosci Lett , vol.424 , pp. 106-110
    • Noble, F.1    Rubira, E.2    Boulanouar, M.3    Palmier, B.4    Plotkine, M.5
  • 40
    • 0028843876 scopus 로고
    • Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6
    • Bellinger FP, Madamba SG, Campbell IL, Siggins GR, (1995) Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6. Neurosci Lett 198: 95-98.
    • (1995) Neurosci Lett , vol.198 , pp. 95-98
    • Bellinger, F.P.1    Madamba, S.G.2    Campbell, I.L.3    Siggins, G.R.4
  • 41
    • 0031028141 scopus 로고    scopus 로고
    • Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
    • Heyser CJ, Masliah E, Samimi A, Campbell IL, Gold LH, (1997) Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc Natl Acad Sci U S A 94: 1500-1505.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1500-1505
    • Heyser, C.J.1    Masliah, E.2    Samimi, A.3    Campbell, I.L.4    Gold, L.H.5
  • 42
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje ML, Toda H, Palmer TD, (2003) Inflammatory blockade restores adult hippocampal neurogenesis. Science 302: 1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 45
    • 0038730942 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor/TrkB signaling in memory processes
    • Yamada K, Nabeshima T, (2003) Brain-derived neurotrophic factor/TrkB signaling in memory processes. J Pharmacol Sci 91: 267-270.
    • (2003) J Pharmacol Sci , vol.91 , pp. 267-270
    • Yamada, K.1    Nabeshima, T.2
  • 46
    • 77952508732 scopus 로고    scopus 로고
    • Neural control of feeding behavior: Overview and clinical correlations
    • Benarroch EE, (2010) Neural control of feeding behavior: Overview and clinical correlations. Neurology 74: 1643-1650.
    • (2010) Neurology , vol.74 , pp. 1643-1650
    • Benarroch, E.E.1
  • 47
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • Martinowich K, Manji H, Lu B, (2007) New insights into BDNF function in depression and anxiety. Nat Neurosci 10: 1089-1093.
    • (2007) Nat Neurosci , vol.10 , pp. 1089-1093
    • Martinowich, K.1    Manji, H.2    Lu, B.3
  • 48
    • 4444338123 scopus 로고    scopus 로고
    • BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration
    • Barrientos RM, Sprunger DB, Campeau S, Watkins LR, Rudy JW, et al. (2004) BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. J Neuroimmunol 155: 119-126.
    • (2004) J Neuroimmunol , vol.155 , pp. 119-126
    • Barrientos, R.M.1    Sprunger, D.B.2    Campeau, S.3    Watkins, L.R.4    Rudy, J.W.5
  • 49
    • 33644910893 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats
    • Tanaka S, Ide M, Shibutani T, Ohtaki H, Numazawa S, et al. (2006) Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. J Neurosci Res 83: 557-566.
    • (2006) J Neurosci Res , vol.83 , pp. 557-566
    • Tanaka, S.1    Ide, M.2    Shibutani, T.3    Ohtaki, H.4    Numazawa, S.5
  • 50
    • 45249088290 scopus 로고    scopus 로고
    • Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction
    • Tong L, Balazs R, Soiampornkul R, Thangnipon W, Cotman CW, (2008) Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction. Neurobiol Aging 29: 1380-1393.
    • (2008) Neurobiol Aging , vol.29 , pp. 1380-1393
    • Tong, L.1    Balazs, R.2    Soiampornkul, R.3    Thangnipon, W.4    Cotman, C.W.5
  • 51
    • 77249153620 scopus 로고    scopus 로고
    • Cognitive impairment following high fat diet consumption is associated with brain inflammation
    • Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, et al. (2010) Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol 219: 25-32.
    • (2010) J Neuroimmunol , vol.219 , pp. 25-32
    • Pistell, P.J.1    Morrison, C.D.2    Gupta, S.3    Knight, A.G.4    Keller, J.N.5
  • 52
    • 34147119059 scopus 로고    scopus 로고
    • Metabolic syndrome and cognitive decline
    • Yaffe K, (2007) Metabolic syndrome and cognitive decline. Curr Alzheimer Res 4: 123-126.
    • (2007) Curr Alzheimer Res , vol.4 , pp. 123-126
    • Yaffe, K.1
  • 53
    • 79958865792 scopus 로고    scopus 로고
    • Relationship between adiposity, emotional status and eating behaviour in obese women: role of inflammation
    • Capuron L, Poitou C, Machaux-Tholliez D, Frochot V, Bouillot JL, et al. (2010) Relationship between adiposity, emotional status and eating behaviour in obese women: role of inflammation. Psychol Med pp. 1-12.
    • (2010) Psychol Med , pp. 1-12
    • Capuron, L.1    Poitou, C.2    Machaux-Tholliez, D.3    Frochot, V.4    Bouillot, J.L.5
  • 54
    • 54149116720 scopus 로고    scopus 로고
    • Depressive symptoms and metabolic syndrome: is inflammation the underlying link?
    • Capuron L, Su S, Miller AH, Bremner JD, Goldberg J, et al. (2008) Depressive symptoms and metabolic syndrome: is inflammation the underlying link? Biol Psychiatry 64: 896-900.
    • (2008) Biol Psychiatry , vol.64 , pp. 896-900
    • Capuron, L.1    Su, S.2    Miller, A.H.3    Bremner, J.D.4    Goldberg, J.5
  • 55
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice
    • Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495.
    • (1996) Cell , vol.84 , pp. 491-495
    • Chen, H.1    Charlat, O.2    Tartaglia, L.A.3    Woolf, E.A.4    Weng, X.5
  • 56
    • 3042598376 scopus 로고    scopus 로고
    • Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation
    • Naguib G, Al-Mashat H, Desta T, Graves DT, (2004) Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation. J Invest Dermatol 123: 87-92.
    • (2004) J Invest Dermatol , vol.123 , pp. 87-92
    • Naguib, G.1    Al-Mashat, H.2    Desta, T.3    Graves, D.T.4
  • 57
    • 77951877918 scopus 로고    scopus 로고
    • Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation
    • Rummel C, Inoue W, Poole S, Luheshi GN, (2010) Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation. Mol Psychiatry 15: 523-534.
    • (2010) Mol Psychiatry , vol.15 , pp. 523-534
    • Rummel, C.1    Inoue, W.2    Poole, S.3    Luheshi, G.N.4
  • 58
    • 17044425940 scopus 로고    scopus 로고
    • IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes
    • O'Connor JC, Satpathy A, Hartman ME, Horvath EM, Kelley KW, et al. (2005) IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes. J Immunol 174: 4991-4997.
    • (2005) J Immunol , vol.174 , pp. 4991-4997
    • O'Connor, J.C.1    Satpathy, A.2    Hartman, M.E.3    Horvath, E.M.4    Kelley, K.W.5
  • 59
    • 0037008873 scopus 로고    scopus 로고
    • Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents
    • Li XL, Aou S, Oomura Y, Hori N, Fukunaga K, et al. (2002) Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. Neuroscience 113: 607-615.
    • (2002) Neuroscience , vol.113 , pp. 607-615
    • Li, X.L.1    Aou, S.2    Oomura, Y.3    Hori, N.4    Fukunaga, K.5
  • 60
    • 77649180893 scopus 로고    scopus 로고
    • Prandial increase of leptin in the brain activates spatial learning and memory
    • Oomura Y, Aou S, Fukunaga K, (2010) Prandial increase of leptin in the brain activates spatial learning and memory. Pathophysiology 17: 119-127.
    • (2010) Pathophysiology , vol.17 , pp. 119-127
    • Oomura, Y.1    Aou, S.2    Fukunaga, K.3
  • 61
    • 39749137437 scopus 로고    scopus 로고
    • Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
    • Stranahan AM, Arumugam TV, Cutler RG, Lee K, Egan JM, et al. (2008) Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci 11: 309-317.
    • (2008) Nat Neurosci , vol.11 , pp. 309-317
    • Stranahan, A.M.1    Arumugam, T.V.2    Cutler, R.G.3    Lee, K.4    Egan, J.M.5
  • 62
    • 70349262248 scopus 로고    scopus 로고
    • Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
    • Stranahan AM, Lee K, Martin B, Maudsley S, Golden E, et al. (2009) Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus 19: 951-961.
    • (2009) Hippocampus , vol.19 , pp. 951-961
    • Stranahan, A.M.1    Lee, K.2    Martin, B.3    Maudsley, S.4    Golden, E.5
  • 63
    • 0034078621 scopus 로고    scopus 로고
    • Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice
    • Dellu F, Contarino A, Simon H, Koob GF, Gold LH, (2000) Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice. Neurobiol Learn Mem 73: 31-48.
    • (2000) Neurobiol Learn Mem , vol.73 , pp. 31-48
    • Dellu, F.1    Contarino, A.2    Simon, H.3    Koob, G.F.4    Gold, L.H.5
  • 64
    • 67650287040 scopus 로고    scopus 로고
    • Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice
    • Labrousse VF, Costes L, Aubert A, Darnaudery M, Ferreira G, et al. (2009) Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice. PLoS One 4: e6006.
    • (2009) PLoS One , vol.4
    • Labrousse, V.F.1    Costes, L.2    Aubert, A.3    Darnaudery, M.4    Ferreira, G.5
  • 65
    • 34247574175 scopus 로고    scopus 로고
    • The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
    • Dere E, Huston JP, De Souza Silva MA, (2007) The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci Biobehav Rev 31: 673-704.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 673-704
    • Dere, E.1    Huston, J.P.2    de Souza Silva, M.A.3
  • 66
    • 0033735522 scopus 로고    scopus 로고
    • Selective involvement of interleukin-6 in the transcriptional activation of the suppressor of cytokine signaling-3 in the brain during systemic immune challenges
    • Lebel E, Vallieres L, Rivest S, (2000) Selective involvement of interleukin-6 in the transcriptional activation of the suppressor of cytokine signaling-3 in the brain during systemic immune challenges. Endocrinology 141: 3749-3763.
    • (2000) Endocrinology , vol.141 , pp. 3749-3763
    • Lebel, E.1    Vallieres, L.2    Rivest, S.3
  • 67
    • 33845459603 scopus 로고    scopus 로고
    • Animal models of mood disorders: Recent developments
    • Cryan JF, Slattery DA, (2007) Animal models of mood disorders: Recent developments. Curr Opin Psychiatry 20: 1-7.
    • (2007) Curr Opin Psychiatry , vol.20 , pp. 1-7
    • Cryan, J.F.1    Slattery, D.A.2
  • 68
    • 0343714599 scopus 로고    scopus 로고
    • Decreased 5-HT transporter mRNA in neurons of the dorsal raphe nucleus and behavioral depression in the obese leptin-deficient ob/ob mouse
    • Collin M, Hakansson-Ovesjo ML, Misane I, Ogren SO, Meister B, (2000) Decreased 5-HT transporter mRNA in neurons of the dorsal raphe nucleus and behavioral depression in the obese leptin-deficient ob/ob mouse. Brain Res Mol Brain Res 81: 51-61.
    • (2000) Brain Res Mol Brain Res , vol.81 , pp. 51-61
    • Collin, M.1    Hakansson-Ovesjo, M.L.2    Misane, I.3    Ogren, S.O.4    Meister, B.5
  • 69
    • 54249128702 scopus 로고    scopus 로고
    • Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior
    • Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, et al. (2008) Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior. Mol Psychiatry 13: 1028-1042.
    • (2008) Mol Psychiatry , vol.13 , pp. 1028-1042
    • Lu, A.1    Steiner, M.A.2    Whittle, N.3    Vogl, A.M.4    Walser, S.M.5
  • 70
    • 34248581135 scopus 로고    scopus 로고
    • Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior
    • Frenois F, Moreau M, O'Connor J, Lawson M, Micon C, et al. (2007) Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior. Psychoneuroendocrinology 32: 516-531.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 516-531
    • Frenois, F.1    Moreau, M.2    O'Connor, J.3    Lawson, M.4    Micon, C.5
  • 71
    • 36949034086 scopus 로고    scopus 로고
    • Arousal and stress effects on consolidation and reconsolidation of recognition memory
    • Maroun M, Akirav I, (2008) Arousal and stress effects on consolidation and reconsolidation of recognition memory. Neuropsychopharmacology 33: 394-405.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 394-405
    • Maroun, M.1    Akirav, I.2
  • 72
    • 1642433171 scopus 로고    scopus 로고
    • Glucocorticoid effects on object recognition memory require training-associated emotional arousal
    • Okuda S, Roozendaal B, McGaugh JL, (2004) Glucocorticoid effects on object recognition memory require training-associated emotional arousal. Proc Natl Acad Sci U S A 101: 853-858.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 853-858
    • Okuda, S.1    Roozendaal, B.2    McGaugh, J.L.3
  • 73
    • 0032077527 scopus 로고    scopus 로고
    • Effects of peripheral administration of LPS on the expression of immunoreactive interleukin-1 alpha, beta, and receptor antagonist in rat brain
    • van Dam AM, Poole S, Schultzberg M, Zavala F, Tilders FJ, (1998) Effects of peripheral administration of LPS on the expression of immunoreactive interleukin-1 alpha, beta, and receptor antagonist in rat brain. Ann N Y Acad Sci 840: 128-138.
    • (1998) Ann N Y Acad Sci , vol.840 , pp. 128-138
    • van Dam, A.M.1    Poole, S.2    Schultzberg, M.3    Zavala, F.4    Tilders, F.J.5
  • 76
    • 1842633557 scopus 로고    scopus 로고
    • The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition
    • Wu A, Ying Z, Gomez-Pinilla F, (2004) The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. Eur J Neurosci 19: 1699-1707.
    • (2004) Eur J Neurosci , vol.19 , pp. 1699-1707
    • Wu, A.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 77
    • 77955093819 scopus 로고    scopus 로고
    • Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring
    • Tozuka Y, Kumon M, Wada E, Onodera M, Mochizuki H, et al. (2010) Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochem Int 57: 235-247.
    • (2010) Neurochem Int , vol.57 , pp. 235-247
    • Tozuka, Y.1    Kumon, M.2    Wada, E.3    Onodera, M.4    Mochizuki, H.5
  • 79
    • 79952814389 scopus 로고    scopus 로고
    • Amygdala circuitry mediating reversible and bidirectional control of anxiety
    • Tye KM, Prakash R, Kim SY, Fenno LE, Grosenick L, et al. (2011) Amygdala circuitry mediating reversible and bidirectional control of anxiety. Nature 471: 358-362.
    • (2011) Nature , vol.471 , pp. 358-362
    • Tye, K.M.1    Prakash, R.2    Kim, S.Y.3    Fenno, L.E.4    Grosenick, L.5
  • 81
    • 57449101122 scopus 로고    scopus 로고
    • The immediate and long-term impact of physical and/or emotional stress from motor vehicle accidents on circulating stress hormones and adipo-cytokines in children and adolescents
    • Pervanidou P, Margeli A, Lazaropoulou C, Papassotiriou I, Chrousos GP, (2008) The immediate and long-term impact of physical and/or emotional stress from motor vehicle accidents on circulating stress hormones and adipo-cytokines in children and adolescents. Stress 11: 438-447.
    • (2008) Stress , vol.11 , pp. 438-447
    • Pervanidou, P.1    Margeli, A.2    Lazaropoulou, C.3    Papassotiriou, I.4    Chrousos, G.P.5
  • 82
    • 39149107769 scopus 로고    scopus 로고
    • Immune challenge induces differential corticosterone and interleukin-6 responsiveness in rats bred for extremes in anxiety-related behavior
    • Salome N, Tasiemski A, Dutriez I, Wigger A, Landgraf R, et al. (2008) Immune challenge induces differential corticosterone and interleukin-6 responsiveness in rats bred for extremes in anxiety-related behavior. Neuroscience 151: 1112-1118.
    • (2008) Neuroscience , vol.151 , pp. 1112-1118
    • Salome, N.1    Tasiemski, A.2    Dutriez, I.3    Wigger, A.4    Landgraf, R.5
  • 83
    • 57549097462 scopus 로고    scopus 로고
    • Analgesic, learning and memory and anxiolytic effects of insulin in mice
    • Akanmu MA, Nwabudike NL, Ilesanmi OR, (2009) Analgesic, learning and memory and anxiolytic effects of insulin in mice. Behav Brain Res 196: 237-241.
    • (2009) Behav Brain Res , vol.196 , pp. 237-241
    • Akanmu, M.A.1    Nwabudike, N.L.2    Ilesanmi, O.R.3
  • 84
    • 77955639045 scopus 로고    scopus 로고
    • Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours
    • Finger BC, Dinan TG, Cryan JF, (2010) Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours. Psychopharmacology 210: 559-568.
    • (2010) Psychopharmacology , vol.210 , pp. 559-568
    • Finger, B.C.1    Dinan, T.G.2    Cryan, J.F.3
  • 85
    • 59649122815 scopus 로고    scopus 로고
    • Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits
    • Kuhad A, Bishnoi M, Tiwari V, Chopra K, (2009) Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits. Pharmacol Biochem Behav 92: 251-259.
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 251-259
    • Kuhad, A.1    Bishnoi, M.2    Tiwari, V.3    Chopra, K.4
  • 86
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
    • Raison CL, Miller AH, (2003) When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 160: 1554-1565.
    • (2003) Am J Psychiatry , vol.160 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 87
    • 57449118499 scopus 로고    scopus 로고
    • Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide
    • Konsman JP, Veeneman J, Combe C, Poole S, Luheshi GN, et al. (2008) Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. Eur J Neurosci 28: 2499-2510.
    • (2008) Eur J Neurosci , vol.28 , pp. 2499-2510
    • Konsman, J.P.1    Veeneman, J.2    Combe, C.3    Poole, S.4    Luheshi, G.N.5
  • 88
    • 0035829390 scopus 로고    scopus 로고
    • Measuring normal and pathological anxiety-like behaviour in mice: a review
    • Belzung C, Griebel G, (2001) Measuring normal and pathological anxiety-like behaviour in mice: a review. Behav Brain Res 125: 141-149.
    • (2001) Behav Brain Res , vol.125 , pp. 141-149
    • Belzung, C.1    Griebel, G.2
  • 89
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108.
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.