메뉴 건너뛰기




Volumn 38, Issue 12, 2015, Pages 2093-2105

Phytochemical regulation of Fyn and AMPK signaling circuitry

Author keywords

AMPK; Antioxidant; Fyn; Metabolic disease; Phytochemical

Indexed keywords

ADENYLATE KINASE; BERBERINE; CAFFEIC ACID; CURCUMIN; DELPHINIDIN; DITHIOTHREITOL; EPIGALLOCATECHIN GALLATE; GENISTEIN; KAZINOL DERIVATIVE; LIGNAN DERIVATIVE; MYRICETIN; PLANT MEDICINAL PRODUCT; POLYPHENOL DERIVATIVE; PROTEIN KINASE FYN; QUERCETIN; RESVERATROL; ROSMARINIC ACID; SAUCHINONE; UNCLASSIFIED DRUG; FYN PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

EID: 84948720915     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-015-0611-x     Document Type: Review
Times cited : (11)

References (121)
  • 1
    • 0033597766 scopus 로고    scopus 로고
    • Fyn and JAK2 mediate Ras activation by reactive oxygen species
    • Abe, J., and B.C. Berk. 1999. Fyn and JAK2 mediate Ras activation by reactive oxygen species. Journal of Biological Chemistry 274(30): 21003-21010.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.30 , pp. 21003-21010
    • Abe, J.1    Berk, B.C.2
  • 3
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • Aggarwal, B.B., and K.B. Harikumar. 2009. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. International Journal of Biochemistry & Cell Biology 41(1): 40-59. doi: 10.1016/j.biocel.2008.06.010.
    • (2009) International Journal of Biochemistry & Cell Biology , vol.41 , Issue.1 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 7
    • 8444225811 scopus 로고    scopus 로고
    • Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: The modifying effects of estrogen
    • Ascherio, A., M.G. Weisskopf, E.J. O'Reilly, M.L. McCullough, E.E. Calle, C. Rodriguez, and M.J. Thun. 2004. Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: The modifying effects of estrogen. American Journal of Epidemiology 160(10): 977-984. doi: 10.1093/aje/kwh312.
    • (2004) American Journal of Epidemiology , vol.160 , Issue.10 , pp. 977-984
    • Ascherio, A.1    Weisskopf, M.G.2    O'Reilly, E.J.3    McCullough, M.L.4    Calle, E.E.5    Rodriguez, C.6    Thun, M.J.7
  • 9
    • 34247566256 scopus 로고    scopus 로고
    • Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn
    • Bastie, C.C., H. Zong, J. Xu, B. Busa, S. Judex, I.J. Kurland, and J.E. Pessin. 2007. Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metabolism 5(5): 371-381. doi: 10.1016/j.cmet.2007.04.005.
    • (2007) Cell Metabolism , vol.5 , Issue.5 , pp. 371-381
    • Bastie, C.C.1    Zong, H.2    Xu, J.3    Busa, B.4    Judex, S.5    Kurland, I.J.6    Pessin, J.E.7
  • 10
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur, J.A., and D.A. Sinclair. 2006. Therapeutic potential of resveratrol: The in vivo evidence. Nature Reviews Drug Discovery 5(6): 493-506. doi: 10.1038/nrd2060.
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 11
    • 7944223078 scopus 로고    scopus 로고
    • Structure and regulation of Src family kinases
    • Boggon, T.J., and M.J. Eck. 2004. Structure and regulation of Src family kinases. Oncogene 23(48): 7918-7927. doi: 10.1038/sj.onc.1208081.
    • (2004) Oncogene , vol.23 , Issue.48 , pp. 7918-7927
    • Boggon, T.J.1    Eck, M.J.2
  • 12
    • 0034917948 scopus 로고    scopus 로고
    • Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells
    • 1:CAS:528:DC%2BD3MXlsVCgur0%3D
    • Boney, C.M., H. Sekimoto, P.A. Gruppuso, and A.R. Frackelton Jr. 2001. Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells. Cell Growth & Differentiation 12(7): 379-386.
    • (2001) Cell Growth & Differentiation , vol.12 , Issue.7 , pp. 379-386
    • Boney, C.M.1    Sekimoto, H.2    Gruppuso, P.A.3    Frackelton, A.R.4
  • 14
    • 7944237784 scopus 로고    scopus 로고
    • The interplay between Src family kinases and receptor tyrosine kinases
    • Bromann, P.A., H. Korkaya, and S.A. Courtneidge. 2004. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23(48): 7957-7968. doi: 10.1038/sj.onc.1208079.
    • (2004) Oncogene , vol.23 , Issue.48 , pp. 7957-7968
    • Bromann, P.A.1    Korkaya, H.2    Courtneidge, S.A.3
  • 15
    • 84856185031 scopus 로고    scopus 로고
    • The pro-apoptotic effect of quercetin in cancer cell lines requires ERbeta-dependent signals
    • Bulzomi, P., P. Galluzzo, A. Bolli, S. Leone, F. Acconcia, and M. Marino. 2012. The pro-apoptotic effect of quercetin in cancer cell lines requires ERbeta-dependent signals. Journal of Cellular Physiology 227(5): 1891-1898. doi: 10.1002/jcp.22917.
    • (2012) Journal of Cellular Physiology , vol.227 , Issue.5 , pp. 1891-1898
    • Bulzomi, P.1    Galluzzo, P.2    Bolli, A.3    Leone, S.4    Acconcia, F.5    Marino, M.6
  • 19
    • 76749172145 scopus 로고    scopus 로고
    • Antioxidant and mitochondrial protective effects of oxidized metabolites of oltipraz
    • Choi, S.H., Y.M. Kim, J.M. Lee, and S.G. Kim. 2010a. Antioxidant and mitochondrial protective effects of oxidized metabolites of oltipraz. Expert Opinion on Drug Metabolism & Toxicology 6(2): 213-224. doi: 10.1517/17425250903427972.
    • (2010) Expert Opinion on Drug Metabolism & Toxicology , vol.6 , Issue.2 , pp. 213-224
    • Choi, S.H.1    Kim, Y.M.2    Lee, J.M.3    Kim, S.G.4
  • 20
    • 77649183809 scopus 로고    scopus 로고
    • AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress
    • Choi, S.H., Y.W. Kim, and S.G. Kim. 2010b. AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress. Biochemical Pharmacology 79(9): 1352-1362. doi: 10.1016/j.bcp.2009.12.011.
    • (2010) Biochemical Pharmacology , vol.79 , Issue.9 , pp. 1352-1362
    • Choi, S.H.1    Kim, Y.W.2    Kim, S.G.3
  • 21
    • 33749267065 scopus 로고    scopus 로고
    • C-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells
    • Choudhury, G.G., L. Mahimainathan, F. Das, B. Venkatesan, and N. Ghosh-Choudhury. 2006. c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells. Cellular Signalling 18(11): 1854-1864. doi: 10.1016/j.cellsig.2006.02.003.
    • (2006) Cellular Signalling , vol.18 , Issue.11 , pp. 1854-1864
    • Choudhury, G.G.1    Mahimainathan, L.2    Das, F.3    Venkatesan, B.4    Ghosh-Choudhury, N.5
  • 22
    • 40749099894 scopus 로고    scopus 로고
    • Pyruvate kinase M2 is a phosphotyrosine-binding protein
    • Christofk, H.R., M.G. Vander Heiden, N. Wu, J.M. Asara, and L.C. Cantley. 2008. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature 452(7184): 181-186. doi: 10.1038/nature06667.
    • (2008) Nature , vol.452 , Issue.7184 , pp. 181-186
    • Christofk, H.R.1    Vander Heiden, M.G.2    Wu, N.3    Asara, J.M.4    Cantley, L.C.5
  • 24
    • 35648944317 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5′-AMP-activated protein kinase
    • Collins, Q.F., H.Y. Liu, J. Pi, Z. Liu, M.J. Quon, and W. Cao. 2007. Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5′-AMP-activated protein kinase. Journal of Biological Chemistry 282(41): 30143-30149. doi: 10.1074/jbc.M702390200.
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.41 , pp. 30143-30149
    • Collins, Q.F.1    Liu, H.Y.2    Pi, J.3    Liu, Z.4    Quon, M.J.5    Cao, W.6
  • 25
    • 20444399897 scopus 로고    scopus 로고
    • The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation
    • Cowan-Jacob, S.W., G. Fendrich, P.W. Manley, W. Jahnke, D. Fabbro, J. Liebetanz, and T. Meyer. 2005. The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation. Structure 13(6): 861-871. doi: 10.1016/j.str.2005.03.012.
    • (2005) Structure , vol.13 , Issue.6 , pp. 861-871
    • Cowan-Jacob, S.W.1    Fendrich, G.2    Manley, P.W.3    Jahnke, W.4    Fabbro, D.5    Liebetanz, J.6    Meyer, T.7
  • 26
    • 0034803430 scopus 로고    scopus 로고
    • AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation
    • Culmsee, C., J. Monnig, B.E. Kemp, and M.P. Mattson. 2001. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. Journal of Molecular Neuroscience 17(1): 45-58. doi: 10.1385/JMN:17:1:45.
    • (2001) Journal of Molecular Neuroscience , vol.17 , Issue.1 , pp. 45-58
    • Culmsee, C.1    Monnig, J.2    Kemp, B.E.3    Mattson, M.P.4
  • 29
    • 0032853934 scopus 로고    scopus 로고
    • Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice
    • 1:CAS:528:DyaK1MXmslelsrc%3D
    • Eberl, G., B. Lowin-Kropf, and H.R. MacDonald. 1999. Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. Journal of Immunology 163(8): 4091-4094.
    • (1999) Journal of Immunology , vol.163 , Issue.8 , pp. 4091-4094
    • Eberl, G.1    Lowin-Kropf, B.2    MacDonald, H.R.3
  • 30
    • 55249084003 scopus 로고    scopus 로고
    • Food labeling: Health claims; Soluble fiber from certain foods and risk of coronary heart disease. Final rule
    • Food, and H. H. S. Drug Administration
    • Food, and H. H. S. Drug Administration. 2008. Food labeling: Health claims; soluble fiber from certain foods and risk of coronary heart disease. Final rule. Federal Register 73(159): 47828-47829.
    • (2008) Federal Register , vol.73 , Issue.159 , pp. 47828-47829
  • 32
    • 43049121395 scopus 로고    scopus 로고
    • Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
    • Fulco, M., Y. Cen, P. Zhao, E.P. Hoffman, M.W. McBurney, A.A. Sauve, and V. Sartorelli. 2008. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Developmental Cell 14(5): 661-673. doi: 10.1016/j.devcel.2008.02.004.
    • (2008) Developmental Cell , vol.14 , Issue.5 , pp. 661-673
    • Fulco, M.1    Cen, Y.2    Zhao, P.3    Hoffman, E.P.4    McBurney, M.W.5    Sauve, A.A.6    Sartorelli, V.7
  • 33
    • 57349169258 scopus 로고    scopus 로고
    • Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues
    • 2607479 1:CAS:528:DC%2BD1MXhtVKrsL8%3D 19029811
    • Fulco, M., and V. Sartorelli. 2008. Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues. Cell Cycle 7(23): 3669-3679.
    • (2008) Cell Cycle , vol.7 , Issue.23 , pp. 3669-3679
    • Fulco, M.1    Sartorelli, V.2
  • 34
    • 0032723181 scopus 로고    scopus 로고
    • The Src family tyrosine kinase Fyn regulates natural killer T cell development
    • 2195667 1:CAS:528:DyaK1MXmslKis7c%3D 10523617
    • Gadue, P., N. Morton, and P.L. Stein. 1999. The Src family tyrosine kinase Fyn regulates natural killer T cell development. Journal of Experimental Medicine 190(8): 1189-1196.
    • (1999) Journal of Experimental Medicine , vol.190 , Issue.8 , pp. 1189-1196
    • Gadue, P.1    Morton, N.2    Stein, P.L.3
  • 35
    • 84907870409 scopus 로고    scopus 로고
    • Recent progress on liver kinase B1 (LKB1): Expression, regulation, downstream signaling and cancer suppressive function
    • Gan, R.Y., and H.B. Li. 2014. Recent progress on liver kinase B1 (LKB1): Expression, regulation, downstream signaling and cancer suppressive function. International Journal of Molecular Sciences 15(9): 16698-16718. doi: 10.3390/ijms150916698.
    • (2014) International Journal of Molecular Sciences , vol.15 , Issue.9 , pp. 16698-16718
    • Gan, R.Y.1    Li, H.B.2
  • 36
    • 78650270601 scopus 로고    scopus 로고
    • Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activation
    • Han, C.Y., S.H. Ki, Y.W. Kim, K. Noh, Y. da Lee, B. Kang, J.H. Ryu, R. Jeon, E.H. Kim, S.J. Hwang, and S.G. Kim. 2011. Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activation. Antioxidants & Redox Signaling 14(2): 187-202. doi: 10.1089/ars.2010.3190.
    • (2011) Antioxidants & Redox Signaling , vol.14 , Issue.2 , pp. 187-202
    • Han, C.Y.1    Ki, S.H.2    Kim, Y.W.3    Noh, K.4    Da Lee, Y.5    Kang, B.6    Ryu, J.H.7    Jeon, R.8    Kim, E.H.9    Hwang, S.J.10    Kim, S.G.11
  • 37
    • 3543140227 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A master switch in glucose and lipid metabolism
    • Hardie, D.G. 2004. AMP-activated protein kinase: A master switch in glucose and lipid metabolism. Reviews in Endocrine and Metabolic Disorders 5(2): 119-125. doi: 10.1023/B:REMD.0000021433.63915.bb.
    • (2004) Reviews in Endocrine and Metabolic Disorders , vol.5 , Issue.2 , pp. 119-125
    • Hardie, D.G.1
  • 38
    • 0029910018 scopus 로고    scopus 로고
    • Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
    • 1:CAS:528:DyaK28XmvVWrurc%3D 8910387
    • Hawley, S.A., M. Davison, A. Woods, S.P. Davies, R.K. Beri, D. Carling, and D.G. Hardie. 1996. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. Journal of Biological Chemistry 271(44): 27879-27887.
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.44 , pp. 27879-27887
    • Hawley, S.A.1    Davison, M.2    Woods, A.3    Davies, S.P.4    Beri, R.K.5    Carling, D.6    Hardie, D.G.7
  • 39
    • 0034070567 scopus 로고    scopus 로고
    • Metabolic stress and altered glucose transport: Activation of AMP-activated protein kinase as a unifying coupling mechanism
    • 1:CAS:528:DC%2BD3cXisFyls7g%3D 10871188
    • Hayashi, T., M.F. Hirshman, N. Fujii, S.A. Habinowski, L.A. Witters, and L.J. Goodyear. 2000. Metabolic stress and altered glucose transport: Activation of AMP-activated protein kinase as a unifying coupling mechanism. Diabetes 49(4): 527-531.
    • (2000) Diabetes , vol.49 , Issue.4 , pp. 527-531
    • Hayashi, T.1    Hirshman, M.F.2    Fujii, N.3    Habinowski, S.A.4    Witters, L.A.5    Goodyear, L.J.6
  • 41
    • 0024431825 scopus 로고
    • Effects of synthetic and naturally occurring flavonoids on Na+, K+ -ATPase: Aspects of the structure-activity relationship and action mechanism
    • 1:CAS:528:DyaK3cXhvVSquw%3D%3D 2552245
    • Hirano, T., K. Oka, and M. Akiba. 1989. Effects of synthetic and naturally occurring flavonoids on Na+, K+ -ATPase: Aspects of the structure-activity relationship and action mechanism. Life Sciences 45(12): 1111-1117.
    • (1989) Life Sciences , vol.45 , Issue.12 , pp. 1111-1117
    • Hirano, T.1    Oka, K.2    Akiba, M.3
  • 42
    • 77954624176 scopus 로고    scopus 로고
    • Flavonoids as protein kinase inhibitors for cancer chemoprevention: Direct binding and molecular modeling
    • Hou, D.X., and T. Kumamoto. 2010. Flavonoids as protein kinase inhibitors for cancer chemoprevention: Direct binding and molecular modeling. Antioxidants & Redox Signaling 13(5): 691-719. doi: 10.1089/ars.2009.2816.
    • (2010) Antioxidants & Redox Signaling , vol.13 , Issue.5 , pp. 691-719
    • Hou, D.X.1    Kumamoto, T.2
  • 44
    • 59449086814 scopus 로고    scopus 로고
    • Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways
    • Hwang, J.T., M.S. Lee, H.J. Kim, M.J. Sung, H.Y. Kim, M.S. Kim, and D.Y. Kwon. 2009a. Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways. Phytotherapy Research 23(2): 262-266. doi: 10.1002/ptr.2606.
    • (2009) Phytotherapy Research , vol.23 , Issue.2 , pp. 262-266
    • Hwang, J.T.1    Lee, M.S.2    Kim, H.J.3    Sung, M.J.4    Kim, H.Y.5    Kim, M.S.6    Kwon, D.Y.7
  • 45
    • 61449168794 scopus 로고    scopus 로고
    • Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha
    • Hwang, M.K., N.J. Kang, Y.S. Heo, K.W. Lee, and H.J. Lee. 2009b. Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha. Biochemical Pharmacology 77(7): 1213-1222. doi: 10.1016/j.bcp.2008.12.021.
    • (2009) Biochemical Pharmacology , vol.77 , Issue.7 , pp. 1213-1222
    • Hwang, M.K.1    Kang, N.J.2    Heo, Y.S.3    Lee, K.W.4    Lee, H.J.5
  • 46
    • 34447526197 scopus 로고    scopus 로고
    • GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
    • Jain, A.K., and A.K. Jaiswal. 2007. GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. Journal of Biological Chemistry 282(22): 16502-16510. doi: 10.1074/jbc.M611336200.
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16502-16510
    • Jain, A.K.1    Jaiswal, A.K.2
  • 47
    • 0031908477 scopus 로고    scopus 로고
    • Effects of the flavonoids quercetin and apigenin on hemostasis in healthy volunteers: Results from an in vitro and a dietary supplement study
    • 1:CAS:528:DyaK1cXntVensQ%3D%3D 9459373
    • Janssen, K., R.P. Mensink, F.J. Cox, J.L. Harryvan, R. Hovenier, P.C. Hollman, and M.B. Katan. 1998. Effects of the flavonoids quercetin and apigenin on hemostasis in healthy volunteers: Results from an in vitro and a dietary supplement study. American Journal of Clinical Nutrition 67(2): 255-262.
    • (1998) American Journal of Clinical Nutrition , vol.67 , Issue.2 , pp. 255-262
    • Janssen, K.1    Mensink, R.P.2    Cox, F.J.3    Harryvan, J.L.4    Hovenier, R.5    Hollman, P.C.6    Katan, M.B.7
  • 48
    • 33947659355 scopus 로고    scopus 로고
    • Homology modeling of human Fyn kinase structure: Discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes
    • Jelic, D., B. Mildner, S. Kostrun, K. Nujic, D. Verbanac, O. Culic, R. Antolovic, and W. Brandt. 2007. Homology modeling of human Fyn kinase structure: Discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes. Journal of Medicinal Chemistry 50(6): 1090-1100. doi: 10.1021/jm0607202.
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.6 , pp. 1090-1100
    • Jelic, D.1    Mildner, B.2    Kostrun, S.3    Nujic, K.4    Verbanac, D.5    Culic, O.6    Antolovic, R.7    Brandt, W.8
  • 49
    • 0029993727 scopus 로고    scopus 로고
    • Active and inactive protein kinases: Structural basis for regulation
    • 1:CAS:528:DyaK28XisFejs7o%3D 8612268
    • Johnson, L.N., M.E. Noble, and D.J. Owen. 1996. Active and inactive protein kinases: Structural basis for regulation. Cell 85(2): 149-158.
    • (1996) Cell , vol.85 , Issue.2 , pp. 149-158
    • Johnson, L.N.1    Noble, M.E.2    Owen, D.J.3
  • 50
    • 84887499625 scopus 로고    scopus 로고
    • MiR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injury
    • Joo, M.S., C.G. Lee, J.H. Koo, and S.G. Kim. 2013. miR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injury. Cell Death and Disease 4: e899. doi: 10.1038/cddis.2013.427.
    • (2013) Cell Death and Disease , vol.4 , pp. e899
    • Joo, M.S.1    Lee, C.G.2    Koo, J.H.3    Kim, S.G.4
  • 52
    • 60149095366 scopus 로고    scopus 로고
    • Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression
    • Kang, N.J., K.W. Lee, B.J. Shin, S.K. Jung, M.K. Hwang, A.M. Bode, Y.S. Heo, H.J. Lee, and Z. Dong. 2009. Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis 30(2): 321-330. doi: 10.1093/carcin/bgn282.
    • (2009) Carcinogenesis , vol.30 , Issue.2 , pp. 321-330
    • Kang, N.J.1    Lee, K.W.2    Shin, B.J.3    Jung, S.K.4    Hwang, M.K.5    Bode, A.M.6    Heo, Y.S.7    Lee, H.J.8    Dong, Z.9
  • 53
    • 79954617446 scopus 로고    scopus 로고
    • Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression
    • Kaspar, J.W., and A.K. Jaiswal. 2011. Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression. FASEB Journal 25(3): 1076-1087. doi: 10.1096/fj.10-171553.
    • (2011) FASEB Journal , vol.25 , Issue.3 , pp. 1076-1087
    • Kaspar, J.W.1    Jaiswal, A.K.2
  • 54
    • 70350606061 scopus 로고    scopus 로고
    • FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
    • Kemper, J.K., Z. Xiao, B. Ponugoti, J. Miao, S. Fang, D. Kanamaluru, S. Tsang, S.Y. Wu, C.M. Chiang, and T.D. Veenstra. 2009. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metabolism 10(5): 392-404. doi: 10.1016/j.cmet.2009.09.009.
    • (2009) Cell Metabolism , vol.10 , Issue.5 , pp. 392-404
    • Kemper, J.K.1    Xiao, Z.2    Ponugoti, B.3    Miao, J.4    Fang, S.5    Kanamaluru, D.6    Tsang, S.7    Wu, S.Y.8    Chiang, C.M.9    Veenstra, T.D.10
  • 55
    • 84865504748 scopus 로고    scopus 로고
    • Enhanced antioxidant effect of prenylated polyphenols as Fyn inhibitor
    • Kim, A.Y., C.G. Lee, Y. da Lee, H. Li, R. Jeon, J.H. Ryu, and S.G. Kim. 2012. Enhanced antioxidant effect of prenylated polyphenols as Fyn inhibitor. Free Radical Biology and Medicine 53(5): 1198-1208. doi: 10.1016/j.freeradbiomed.2012.06.039.
    • (2012) Free Radical Biology and Medicine , vol.53 , Issue.5 , pp. 1198-1208
    • Kim, A.Y.1    Lee, C.G.2    Da Lee, Y.3    Li, H.4    Jeon, R.5    Ryu, J.H.6    Kim, S.G.7
  • 56
    • 84881233274 scopus 로고    scopus 로고
    • Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation
    • Kim, H.S., V. Montana, H.J. Jang, V. Parpura, and J.A. Kim. 2013. Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation. Journal of Biological Chemistry 288(31): 22693-22705. doi: 10.1074/jbc.M113.477505.
    • (2013) Journal of Biological Chemistry , vol.288 , Issue.31 , pp. 22693-22705
    • Kim, H.S.1    Montana, V.2    Jang, H.J.3    Parpura, V.4    Kim, J.A.5
  • 57
    • 74149092293 scopus 로고    scopus 로고
    • Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis
    • Kim, Y.W., Y.M. Kim, Y.M. Yang, T.H. Kim, S.J. Hwang, J.R. Lee, S.C. Kim, and S.G. Kim. 2010. Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis. Free Radical Biology and Medicine 48(4): 567-578. doi: 10.1016/j.freeradbiomed.2009.12.006.
    • (2010) Free Radical Biology and Medicine , vol.48 , Issue.4 , pp. 567-578
    • Kim, Y.W.1    Kim, Y.M.2    Yang, Y.M.3    Kim, T.H.4    Hwang, S.J.5    Lee, J.R.6    Kim, S.C.7    Kim, S.G.8
  • 58
    • 69249240216 scopus 로고    scopus 로고
    • Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury
    • Kim, Y.W., S.M. Lee, S.M. Shin, S.J. Hwang, J.S. Brooks, H.E. Kang, M.G. Lee, S.C. Kim, and S.G. Kim. 2009. Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. Free Radical Biology and Medicine 47(7): 1082-1092. doi: 10.1016/j.freeradbiomed.2009.07.018.
    • (2009) Free Radical Biology and Medicine , vol.47 , Issue.7 , pp. 1082-1092
    • Kim, Y.W.1    Lee, S.M.2    Shin, S.M.3    Hwang, S.J.4    Brooks, J.S.5    Kang, H.E.6    Lee, M.G.7    Kim, S.C.8    Kim, S.G.9
  • 59
    • 0032931358 scopus 로고    scopus 로고
    • Cytotoxic isoprenylated flavans of Broussonetia kazinoki
    • Ko, H.H., M.H. Yen, R.R. Wu, S.J. Won, and C.N. Lin. 1999. Cytotoxic isoprenylated flavans of Broussonetia kazinoki. Journal of Natural Products 62(1): 164-166. doi: 10.1021/np980281c.
    • (1999) Journal of Natural Products , vol.62 , Issue.1 , pp. 164-166
    • Ko, H.H.1    Yen, M.H.2    Wu, R.R.3    Won, S.J.4    Lin, C.N.5
  • 60
    • 84862580442 scopus 로고    scopus 로고
    • Fyn inhibition by cycloalkane-fused 1,2-dithiole-3-thiones enhances antioxidant capacity and protects mitochondria from oxidative injury
    • Koo, J.H., W.H. Lee, C.G. Lee, and S.G. Kim. 2012. Fyn inhibition by cycloalkane-fused 1,2-dithiole-3-thiones enhances antioxidant capacity and protects mitochondria from oxidative injury. Molecular Pharmacology 82(1): 27-36. doi: 10.1124/mol.111.077149.
    • (2012) Molecular Pharmacology , vol.82 , Issue.1 , pp. 27-36
    • Koo, J.H.1    Lee, W.H.2    Lee, C.G.3    Kim, S.G.4
  • 62
    • 56449117024 scopus 로고    scopus 로고
    • AMPK: A metabolic gauge regulating whole-body energy homeostasis
    • Lage, R., C. Dieguez, A. Vidal-Puig, and M. Lopez. 2008. AMPK: A metabolic gauge regulating whole-body energy homeostasis. Trends in Molecular Medicine 14(12): 539-549. doi: 10.1016/j.molmed.2008.09.007.
    • (2008) Trends in Molecular Medicine , vol.14 , Issue.12 , pp. 539-549
    • Lage, R.1    Dieguez, C.2    Vidal-Puig, A.3    Lopez, M.4
  • 63
    • 55549096745 scopus 로고    scopus 로고
    • SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
    • Lan, F., J.M. Cacicedo, N. Ruderman, and Y. Ido. 2008. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. Journal of Biological Chemistry 283(41): 27628-27635. doi: 10.1074/jbc.M805711200.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.41 , pp. 27628-27635
    • Lan, F.1    Cacicedo, J.M.2    Ruderman, N.3    Ido, Y.4
  • 64
    • 84863552974 scopus 로고    scopus 로고
    • Updated knowledge about polyphenols: Functions, bioavailability, metabolism, and health
    • Landete, J.M. 2012. Updated knowledge about polyphenols: Functions, bioavailability, metabolism, and health. Critical Reviews in Food Science and Nutrition 52(10): 936-948. doi: 10.1080/10408398.2010.513779.
    • (2012) Critical Reviews in Food Science and Nutrition , vol.52 , Issue.10 , pp. 936-948
    • Landete, J.M.1
  • 65
    • 0015954420 scopus 로고
    • Effects of quercetin and F1 inhibitor on mitochondrial ATPase and energy-linked reactions in submitochondrial particles
    • 1:CAS:528:DyaE2cXhtFOlsLs%3D 19400030
    • Lang, D.R., and E. Racker. 1974. Effects of quercetin and F1 inhibitor on mitochondrial ATPase and energy-linked reactions in submitochondrial particles. Biochimica et Biophysica Acta 333(2): 180-186.
    • (1974) Biochimica et Biophysica Acta , vol.333 , Issue.2 , pp. 180-186
    • Lang, D.R.1    Racker, E.2
  • 66
    • 84862778692 scopus 로고    scopus 로고
    • Farnesoid X receptor protects hepatocytes from injury by repressing miR-199a-3p, which increases levels of LKB1
    • 3578415 1:CAS:528:DC%2BC38XktlCitbg%3D 22265968
    • Lee, C.G., Y.W. Kim, E.H. Kim, Z. Meng, W. Huang, S.J. Hwang, and S.G. Kim. 2012. Farnesoid X receptor protects hepatocytes from injury by repressing miR-199a-3p, which increases levels of LKB1. Gastroenterology 142(5): 1206-1217.
    • (2012) Gastroenterology , vol.142 , Issue.5 , pp. 1206-1217
    • Lee, C.G.1    Kim, Y.W.2    Kim, E.H.3    Meng, Z.4    Huang, W.5    Hwang, S.J.6    Kim, S.G.7
  • 68
    • 80053466167 scopus 로고    scopus 로고
    • Sauchinone suppresses pro-inflammatory mediators by inducing heme oxygenase-1 in RAW264.7 macrophages
    • 1:CAS:528:DC%2BC3MXhsFyqtb3L
    • Li, B., D.S. Lee, H.G. Choi, K.S. Kim, D.G. Kang, H.S. Lee, G.S. Jeong, and Y.C. Kim. 2011. Sauchinone suppresses pro-inflammatory mediators by inducing heme oxygenase-1 in RAW264.7 macrophages. Biological & Pharmaceutical Bulletin 34(10): 1566-1571.
    • (2011) Biological & Pharmaceutical Bulletin , vol.34 , Issue.10 , pp. 1566-1571
    • Li, B.1    Lee, D.S.2    Choi, H.G.3    Kim, K.S.4    Kang, D.G.5    Lee, H.S.6    Jeong, G.S.7    Kim, Y.C.8
  • 69
    • 77949683134 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A stress-responsive kinase with implications for cardiovascular disease
    • Li, C., and J.F. Keaney Jr. 2010. AMP-activated protein kinase: A stress-responsive kinase with implications for cardiovascular disease. Current Opinion in Pharmacology 10(2): 111-115. doi: 10.1016/j.coph.2009.11.009.
    • (2010) Current Opinion in Pharmacology , vol.10 , Issue.2 , pp. 111-115
    • Li, C.1    Keaney, J.F.2
  • 71
    • 34748897191 scopus 로고    scopus 로고
    • Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase
    • Liu, G., M. Grifman, J. Macdonald, P. Moller, F. Wong-Staal, and Q.X. Li. 2007. Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase. Journal of Endocrinology 194(3): 569-578. doi: 10.1677/JOE-07-0200.
    • (2007) Journal of Endocrinology , vol.194 , Issue.3 , pp. 569-578
    • Liu, G.1    Grifman, M.2    Macdonald, J.3    Moller, P.4    Wong-Staal, F.5    Li, Q.X.6
  • 72
    • 0023938523 scopus 로고
    • Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat
    • 1:CAS:528:DyaL1cXktFygu7o%3D 3130679
    • Liu, Y.L., B.D. Roebuck, J.D. Yager, J.D. Groopman, and T.W. Kensler. 1988. Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat. Toxicology and Applied Pharmacology 93(3): 442-451.
    • (1988) Toxicology and Applied Pharmacology , vol.93 , Issue.3 , pp. 442-451
    • Liu, Y.L.1    Roebuck, B.D.2    Yager, J.D.3    Groopman, J.D.4    Kensler, T.W.5
  • 73
  • 74
    • 77957933189 scopus 로고    scopus 로고
    • Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity
    • Lu, J., D.M. Wu, Y.L. Zheng, B. Hu, Z.F. Zhang, Q. Shan, Z.H. Zheng, C.M. Liu, and Y.J. Wang. 2010. Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity. The Journal of Pathology 222(2): 199-212. doi: 10.1002/path.2754.
    • (2010) The Journal of Pathology , vol.222 , Issue.2 , pp. 199-212
    • Lu, J.1    Wu, D.M.2    Zheng, Y.L.3    Hu, B.4    Zhang, Z.F.5    Shan, Q.6    Zheng, Z.H.7    Liu, C.M.8    Wang, Y.J.9
  • 75
    • 7944226933 scopus 로고    scopus 로고
    • Not so strange bedfellows: G-protein-coupled receptors and Src family kinases
    • Luttrell, D.K., and L.M. Luttrell. 2004. Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene 23(48): 7969-7978. doi: 10.1038/sj.onc.1208162.
    • (2004) Oncogene , vol.23 , Issue.48 , pp. 7969-7978
    • Luttrell, D.K.1    Luttrell, L.M.2
  • 76
    • 0035989680 scopus 로고    scopus 로고
    • HSP90 as a new therapeutic target for cancer therapy: The story unfolds
    • Maloney, A., and P. Workman. 2002. HSP90 as a new therapeutic target for cancer therapy: The story unfolds. Expert Opinion on Biological Therapy 2(1): 3-24. doi: 10.1517/14712598.2.1.3.
    • (2002) Expert Opinion on Biological Therapy , vol.2 , Issue.1 , pp. 3-24
    • Maloney, A.1    Workman, P.2
  • 78
    • 0030744872 scopus 로고    scopus 로고
    • Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
    • 1:CAS:528:DyaK2sXlsFKrs78%3D 9252391
    • Mastick, C.C., and A.R. Saltiel. 1997. Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. Journal of Biological Chemistry 272(33): 20706-20714.
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20706-20714
    • Mastick, C.C.1    Saltiel, A.R.2
  • 79
    • 34248575149 scopus 로고    scopus 로고
    • Integrating signals from RTKs to ERK/MAPK
    • McKay, M.M., and D.K. Morrison. 2007. Integrating signals from RTKs to ERK/MAPK. Oncogene 26(22): 3113-3121. doi: 10.1038/sj.onc.1210394.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3113-3121
    • McKay, M.M.1    Morrison, D.K.2
  • 82
    • 80051690439 scopus 로고    scopus 로고
    • Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression
    • Niture, S.K., A.K. Jain, P.M. Shelton, and A.K. Jaiswal. 2011. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression. Journal of Biological Chemistry 286(33): 28821-28832. doi: 10.1074/jbc.M111.255042.
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.33 , pp. 28821-28832
    • Niture, S.K.1    Jain, A.K.2    Shelton, P.M.3    Jaiswal, A.K.4
  • 83
    • 0030747399 scopus 로고    scopus 로고
    • Biological effects of myricetin
    • 1:CAS:528:DyaK2sXkvFGiu7s%3D 9251891
    • Ong, K.C., and H.E. Khoo. 1997. Biological effects of myricetin. General Pharmacology 29(2): 121-126.
    • (1997) General Pharmacology , vol.29 , Issue.2 , pp. 121-126
    • Ong, K.C.1    Khoo, H.E.2
  • 84
    • 0033553885 scopus 로고    scopus 로고
    • Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase
    • 2133143 1:CAS:528:DyaK1MXjvVKiurg%3D 10366594
    • Osterhout, D.J., A. Wolven, R.M. Wolf, M.D. Resh, and M.V. Chao. 1999. Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase. Journal of Cell Biology 145(6): 1209-1218.
    • (1999) Journal of Cell Biology , vol.145 , Issue.6 , pp. 1209-1218
    • Osterhout, D.J.1    Wolven, A.2    Wolf, R.M.3    Resh, M.D.4    Chao, M.V.5
  • 88
    • 4444233869 scopus 로고    scopus 로고
    • Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) delta in skeletal muscle
    • Rosenzweig, T., S. Aga-Mizrachi, A. Bak, and S.R. Sampson. 2004. Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) delta in skeletal muscle. Cellular Signalling 16(11): 1299-1308. doi: 10.1016/j.cellsig.2004.03.015.
    • (2004) Cellular Signalling , vol.16 , Issue.11 , pp. 1299-1308
    • Rosenzweig, T.1    Aga-Mizrachi, S.2    Bak, A.3    Sampson, S.R.4
  • 89
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • Ross, J.A., and C.M. Kasum. 2002. Dietary flavonoids: Bioavailability, metabolic effects, and safety. Annual Review of Nutrition 22: 19-34. doi: 10.1146/annurev.nutr.22.111401.144957.
    • (2002) Annual Review of Nutrition , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 90
    • 68749118353 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes
    • Sanchez-Wandelmer, J., A. Davalos, E. Herrera, M. Giera, S. Cano, G. de la Pena, M.A. Lasuncion, and R. Busto. 2009. Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes. Biochimica et Biophysica Acta 1788(9): 1731-1739. doi: 10.1016/j.bbamem.2009.05.002.
    • (2009) Biochimica et Biophysica Acta , vol.1788 , Issue.9 , pp. 1731-1739
    • Sanchez-Wandelmer, J.1    Davalos, A.2    Herrera, E.3    Giera, M.4    Cano, S.5    De La Pena, G.6    Lasuncion, M.A.7    Busto, R.8
  • 91
    • 0344825239 scopus 로고    scopus 로고
    • Fyn is required for oxidative- and hyperosmotic-stress-induced tyrosine phosphorylation of caveolin-1
    • Sanguinetti, A.R., H. Cao, and C. Corley Mastick. 2003. Fyn is required for oxidative- and hyperosmotic-stress-induced tyrosine phosphorylation of caveolin-1. Biochemical Journal 376(Pt 1): 159-168. doi: 10.1042/bj20030336.
    • (2003) Biochemical Journal , vol.376 , Issue.PT 1 , pp. 159-168
    • Sanguinetti, A.R.1    Cao, H.2    Corley Mastick, C.3
  • 92
    • 84875051800 scopus 로고    scopus 로고
    • Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase alpha content and changes in mitochondrial respiratory complexes
    • Serrano, J.C., H. Gonzalo-Benito, M. Jove, S. Fourcade, A. Cassanye, J. Boada, M.A. Delgado, A.E. Espinel, R. Pamplona, and M. Portero-Otin. 2013. Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase alpha content and changes in mitochondrial respiratory complexes. Molecular Nutrition & Food Research 57(3): 459-470. doi: 10.1002/mnfr.201200513.
    • (2013) Molecular Nutrition & Food Research , vol.57 , Issue.3 , pp. 459-470
    • Serrano, J.C.1    Gonzalo-Benito, H.2    Jove, M.3    Fourcade, S.4    Cassanye, A.5    Boada, J.6    Delgado, M.A.7    Espinel, A.E.8    Pamplona, R.9    Portero-Otin, M.10
  • 93
    • 70349324339 scopus 로고    scopus 로고
    • Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway
    • Shin, S.M., I.J. Cho, and S.G. Kim. 2009. Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway. Molecular Pharmacology 76(4): 884-895. doi: 10.1124/mol.109.058479.
    • (2009) Molecular Pharmacology , vol.76 , Issue.4 , pp. 884-895
    • Shin, S.M.1    Cho, I.J.2    Kim, S.G.3
  • 94
    • 58849093275 scopus 로고    scopus 로고
    • Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners
    • Shin, S.M., and S.G. Kim. 2009. Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners. Molecular Pharmacology 75(1): 242-253. doi: 10.1124/mol.108.051128.
    • (2009) Molecular Pharmacology , vol.75 , Issue.1 , pp. 242-253
    • Shin, S.M.1    Kim, S.G.2
  • 95
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
    • Singh, B.N., S. Shankar, and R.K. Srivastava. 2011. Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications. Biochemical Pharmacology 82(12): 1807-1821. doi: 10.1016/j.bcp.2011.07.093.
    • (2011) Biochemical Pharmacology , vol.82 , Issue.12 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 99
    • 15844409347 scopus 로고    scopus 로고
    • The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation
    • 1:CAS:528:DyaK28XivVaqtro%3D 8631859
    • Sun, X.J., S. Pons, T. Asano, M.G. Myers Jr, E. Glasheen, and M.F. White. 1996. The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation. Journal of Biological Chemistry 271(18): 10583-10587.
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.18 , pp. 10583-10587
    • Sun, X.J.1    Pons, S.2    Asano, T.3    Myers, M.G.4    Glasheen, E.5    White, M.F.6
  • 100
    • 17544363201 scopus 로고    scopus 로고
    • Hepatoprotective diastereomeric lignans from Saururus chinensis herbs
    • 1:CAS:528:DC%2BD3cXjt1eltLY%3D 10924192
    • Sung, S.H., and Y.C. Kim. 2000. Hepatoprotective diastereomeric lignans from Saururus chinensis herbs. Journal of Natural Products 63(7): 1019-1021.
    • (2000) Journal of Natural Products , vol.63 , Issue.7 , pp. 1019-1021
    • Sung, S.H.1    Kim, Y.C.2
  • 103
    • 27144489669 scopus 로고    scopus 로고
    • AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
    • Terai, K., Y. Hiramoto, M. Masaki, S. Sugiyama, T. Kuroda, M. Hori, I. Kawase, and H. Hirota. 2005. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Molecular and Cellular Biology 25(21): 9554-9575. doi: 10.1128/MCB.25.21.9554-9575.2005.
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.21 , pp. 9554-9575
    • Terai, K.1    Hiramoto, Y.2    Masaki, M.3    Sugiyama, S.4    Kuroda, T.5    Hori, M.6    Kawase, I.7    Hirota, H.8
  • 104
    • 84876453706 scopus 로고    scopus 로고
    • Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction
    • Tse, M.C., X. Liu, S. Yang, K. Ye, and C.B. Chan. 2013. Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction. Molecular and Cellular Biology 33(9): 1797-1808. doi: 10.1128/mcb.01410-12.
    • (2013) Molecular and Cellular Biology , vol.33 , Issue.9 , pp. 1797-1808
    • Tse, M.C.1    Liu, X.2    Yang, S.3    Ye, K.4    Chan, C.B.5
  • 105
    • 48449084609 scopus 로고    scopus 로고
    • Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action
    • Turner, N., J.Y. Li, A. Gosby, S.W. To, Z. Cheng, H. Miyoshi, M.M. Taketo, G.J. Cooney, E.W. Kraegen, D.E. James, L.H. Hu, J. Li, and J.M. Ye. 2008. Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes 57(5): 1414-1418. doi: 10.2337/db07-1552.
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1414-1418
    • Turner, N.1    Li, J.Y.2    Gosby, A.3    To, S.W.4    Cheng, Z.5    Miyoshi, H.6    Taketo, M.M.7    Cooney, G.J.8    Kraegen, E.W.9    James, D.E.10    Hu, L.H.11    Li, J.12    Ye, J.M.13
  • 106
    • 0033558323 scopus 로고    scopus 로고
    • Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination
    • 1:CAS:528:DyaK1MXhtFOhtbk%3D 9952416
    • Umemori, H., Y. Kadowaki, K. Hirosawa, Y. Yoshida, K. Hironaka, H. Okano, and T. Yamamoto. 1999. Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination. Journal of Neuroscience 19(4): 1393-1397.
    • (1999) Journal of Neuroscience , vol.19 , Issue.4 , pp. 1393-1397
    • Umemori, H.1    Kadowaki, Y.2    Hirosawa, K.3    Yoshida, Y.4    Hironaka, K.5    Okano, H.6    Yamamoto, T.7
  • 107
    • 21444448910 scopus 로고    scopus 로고
    • Coffee consumption and risk of type 2 diabetes: A systematic review
    • van Dam, R.M., and F.B. Hu. 2005. Coffee consumption and risk of type 2 diabetes: A systematic review. JAMA 294(1): 97-104. doi: 10.1001/jama.294.1.97.
    • (2005) JAMA , vol.294 , Issue.1 , pp. 97-104
    • Van Dam, R.M.1    Hu, F.B.2
  • 108
    • 70449365855 scopus 로고    scopus 로고
    • Fyn kinase function in lipid utilization: A new upstream regulator of AMPK activity?
    • Vatish, M., E. Yamada, J.E. Pessin, and C.C. Bastie. 2009. Fyn kinase function in lipid utilization: A new upstream regulator of AMPK activity? Archives of Physiology and Biochemistry 115(4): 191-198. doi: 10.1080/13813450903164348.
    • (2009) Archives of Physiology and Biochemistry , vol.115 , Issue.4 , pp. 191-198
    • Vatish, M.1    Yamada, E.2    Pessin, J.E.3    Bastie, C.C.4
  • 109
    • 0029947174 scopus 로고    scopus 로고
    • Molecular effects of genistein on estrogen receptor mediated pathways
    • 8625449
    • Wang, T.T., N. Sathyamoorthy, and J.M. Phang. 1996. Molecular effects of genistein on estrogen receptor mediated pathways. Carcinogenesis 17(2): 271-275.
    • (1996) Carcinogenesis , vol.17 , Issue.2 , pp. 271-275
    • Wang, T.T.1    Sathyamoorthy, N.2    Phang, J.M.3
  • 110
    • 23044437445 scopus 로고    scopus 로고
    • Ca2 +/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
    • Woods, A., K. Dickerson, R. Heath, S.P. Hong, M. Momcilovic, S.R. Johnstone, M. Carlson, and D. Carling. 2005. Ca2 +/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metabolism 2(1): 21-33. doi: 10.1016/j.cmet.2005.06.005.
    • (2005) Cell Metabolism , vol.2 , Issue.1 , pp. 21-33
    • Woods, A.1    Dickerson, K.2    Heath, R.3    Hong, S.P.4    Momcilovic, M.5    Johnstone, S.R.6    Carlson, M.7    Carling, D.8
  • 112
    • 33745339103 scopus 로고    scopus 로고
    • Down-regulation of p210(bcr/abl) by curcumin involves disrupting molecular chaperone functions of Hsp90
    • Wu, L.X., J.H. Xu, X.W. Huang, K.Z. Zhang, C.X. Wen, and Y.Z. Chen. 2006. Down-regulation of p210(bcr/abl) by curcumin involves disrupting molecular chaperone functions of Hsp90. Acta Pharmacologica Sinica 27(6): 694-699. doi: 10.1111/j.1745-7254.2006.00326.x.
    • (2006) Acta Pharmacologica Sinica , vol.27 , Issue.6 , pp. 694-699
    • Wu, L.X.1    Xu, J.H.2    Huang, X.W.3    Zhang, K.Z.4    Wen, C.X.5    Chen, Y.Z.6
  • 114
    • 84863288474 scopus 로고    scopus 로고
    • Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells
    • Xu, Y., L. Nie, Y.G. Yin, J.L. Tang, J.Y. Zhou, D.D. Li, and S.W. Zhou. 2012. Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells. Toxicology and Applied Pharmacology 259(3): 395-401. doi: 10.1016/j.taap.2011.09.028.
    • (2012) Toxicology and Applied Pharmacology , vol.259 , Issue.3 , pp. 395-401
    • Xu, Y.1    Nie, L.2    Yin, Y.G.3    Tang, J.L.4    Zhou, J.Y.5    Li, D.D.6    Zhou, S.W.7
  • 115
    • 75149117805 scopus 로고    scopus 로고
    • Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
    • Yamada, E., J.E. Pessin, I.J. Kurland, G.J. Schwartz, and C.C. Bastie. 2010. Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1. Cell Metabolism 11(2): 113-124. doi: 10.1016/j.cmet.2009.12.010.
    • (2010) Cell Metabolism , vol.11 , Issue.2 , pp. 113-124
    • Yamada, E.1    Pessin, J.E.2    Kurland, I.J.3    Schwartz, G.J.4    Bastie, C.C.5
  • 116
    • 77649151829 scopus 로고    scopus 로고
    • Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways
    • Yan, G.R., C.L. Xiao, G.W. He, X.F. Yin, N.P. Chen, Y. Cao, and Q.Y. He. 2010. Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways. Proteomics 10(5): 976-986. doi: 10.1002/pmic.200900662.
    • (2010) Proteomics , vol.10 , Issue.5 , pp. 976-986
    • Yan, G.R.1    Xiao, C.L.2    He, G.W.3    Yin, X.F.4    Chen, N.P.5    Cao, Y.6    He, Q.Y.7
  • 117
    • 77955753666 scopus 로고    scopus 로고
    • AMPK-associated signaling to bridge the gap between fuel metabolism and hepatocyte viability
    • 2921082 1:CAS:528:DC%2BC3cXhtVens7jP 20698033
    • Yang, Y.M., C.Y. Han, Y.J. Kim, and S.G. Kim. 2010. AMPK-associated signaling to bridge the gap between fuel metabolism and hepatocyte viability. World Journal of Gastroenterology 16(30): 3731-3742.
    • (2010) World Journal of Gastroenterology , vol.16 , Issue.30 , pp. 3731-3742
    • Yang, Y.M.1    Han, C.Y.2    Kim, Y.J.3    Kim, S.G.4
  • 119
    • 56249128623 scopus 로고    scopus 로고
    • Dithiolethiones for cancer chemoprevention: Where do we stand?
    • Zhang, Y., and R. Munday. 2008. Dithiolethiones for cancer chemoprevention: Where do we stand? Molecular Cancer Therapeutics 7(11): 3470-3479. doi: 10.1158/1535-7163.mct-08-0625.
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.11 , pp. 3470-3479
    • Zhang, Y.1    Munday, R.2
  • 120
    • 84900344034 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance
    • Zhou, J., B.L. Farah, R.A. Sinha, Y. Wu, B.K. Singh, B.H. Bay, C.S. Yang, and P.M. Yen. 2014. Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance. PLoS One 9(1): e87161. doi: 10.1371/journal.pone.0087161.
    • (2014) PLoS One , vol.9 , Issue.1 , pp. e87161
    • Zhou, J.1    Farah, B.L.2    Sinha, R.A.3    Wu, Y.4    Singh, B.K.5    Bay, B.H.6    Yang, C.S.7    Yen, P.M.8
  • 121
    • 66449113058 scopus 로고    scopus 로고
    • Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: Cytoprotection against oxidative/electrophilic stress and doxorubicin toxicity
    • Zhu, H., Z. Jia, K. Zhou, H.P. Misra, A. Santo, K.L. Gabrielson, and Y. Li. 2009. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: Cytoprotection against oxidative/electrophilic stress and doxorubicin toxicity. Experimental Biology and Medicine (Maywood) 234(4): 418-429. doi: 10.3181/0811-rm-340.
    • (2009) Experimental Biology and Medicine (Maywood) , vol.234 , Issue.4 , pp. 418-429
    • Zhu, H.1    Jia, Z.2    Zhou, K.3    Misra, H.P.4    Santo, A.5    Gabrielson, K.L.6    Li, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.