-
2
-
-
0037376001
-
Protein tyrosine phosphatases: The quest for negative regulators of insulin action
-
Asante-Appiah E, Kennedy BP. (2003). Protein tyrosine phosphatases: the quest for negative regulators of insulin action. Am J Physiol Endocrinol Metab 284:E663-70.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Asante-Appiah, E.1
Kennedy, B.P.2
-
3
-
-
0038614742
-
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD
-
Baas AF, Boudeau J, Sapkota GP, Smit L, Medema R, Morrice NA, Alessi DR, Clevers HC. (2003). Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J 22:3062-3072
-
(2003)
EMBO J
, vol.22
, pp. 3062-3072
-
-
Baas, A.F.1
Boudeau, J.2
Sapkota, G.P.3
Smit, L.4
Medema, R.5
Morrice, N.A.6
Alessi, D.R.7
Clevers, H.C.8
-
4
-
-
34247566256
-
Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn
-
Bastie CC, Zong H, Xu J, Busa B, Judex S, Kurland IJ, Pessin JE. (2007). Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metab 5:371-381
-
(2007)
Cell Metab
, vol.5
, pp. 371-381
-
-
Bastie, C.C.1
Zong, H.2
Xu, J.3
Busa, B.4
Judex, S.5
Kurland, I.J.6
Pessin, J.E.7
-
5
-
-
7944223078
-
Structure and regulation of Src family kinases
-
Boggon TJ, Eck MJ. (2004). Structure and regulation of Src family kinases. Oncogene 23:7918-7927
-
(2004)
Oncogene
, vol.23
, pp. 7918-7927
-
-
Boggon, T.J.1
Eck, M.J.2
-
6
-
-
0141753981
-
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
-
Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. (2003). MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J 22:5102-5114
-
(2003)
EMBO J
, vol.22
, pp. 5102-5114
-
-
Boudeau, J.1
Baas, A.F.2
Deak, M.3
Morrice, N.A.4
Kieloch, A.5
Schutkowski, M.6
Prescott, A.R.7
Clevers, H.C.8
Alessi, D.R.9
-
7
-
-
0029896163
-
Regulation, substrates and functions of src
-
Brown MT, Cooper JA. (1996). Regulation, substrates and functions of src. Biochim Biophys Acta 1287:121-149
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
8
-
-
0028169889
-
Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells
-
Bull HA, Brickell PM, Dowd PM. (1994). Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells. FEBS Lett 351: 41-44
-
(1994)
FEBS Lett
, vol.351
, pp. 41-44
-
-
Bull, H.A.1
Brickell, P.M.2
Dowd, P.M.3
-
9
-
-
21144453387
-
Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligandinduced insulin receptor instability in skeletal muscle
-
Capozza F, Combs TP, Cohen AW, Cho YR, Park SY, Schubert W, Williams TM, Brasaemle DL, Jelicks LA, Scherer PE, Kim JK, Lisanti MP. (2005). Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligandinduced insulin receptor instability in skeletal muscle. Am J Physiol Cell Physiol 288:C1317-31.
-
(2005)
Am J Physiol Cell Physiol
, vol.288
-
-
Capozza, F.1
Combs, T.P.2
Cohen, A.W.3
Cho, Y.R.4
Park, S.Y.5
Schubert, W.6
Williams, T.M.7
Brasaemle, D.L.8
Jelicks, L.A.9
Scherer, P.E.10
Kim, J.K.11
Lisanti, M.P.12
-
10
-
-
0028288927
-
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
-
Chan AC, Desai DM, and Weiss A. (1994). The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol 12:555-592
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.M.2
Weiss, A.3
-
11
-
-
29144452123
-
Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases
-
Chong YP, Ia KK, Mulhern TD, and Cheng HC. (2005a). Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases. Biochim Biophys Acta 1754:210-220
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 210-220
-
-
Chong, Y.P.1
Ia, K.K.2
Mulhern, T.D.3
Cheng, H.C.4
-
12
-
-
32144460477
-
C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)-endogenous negative regulators of Src-family protein kinases
-
Chong YP, Mulhern TD, Cheng HC. (2005b). C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)-endogenous negative regulators of Src-family protein kinases. Growth Factors 23:233-244
-
(2005)
Growth Factors
, vol.23
, pp. 233-244
-
-
Chong, Y.P.1
Mulhern, T.D.2
Cheng, H.C.3
-
13
-
-
2442710106
-
A novel non-catalytic mechanism employed by the C-terminal Srchomologous kinase to inhibit Src-family kinase activity
-
Chong YP, Mulhern TD, Zhu HJ, Fujita DJ, Bjorge JD, Tantiongco JP, Sotirellis N, Lio DS, Scholz G, Cheng HC. (2004). A novel non-catalytic mechanism employed by the C-terminal Srchomologous kinase to inhibit Src-family kinase activity. J Biol Chem 279:20752-20766
-
(2004)
J Biol Chem
, vol.279
, pp. 20752-20766
-
-
Chong, Y.P.1
Mulhern, T.D.2
Zhu, H.J.3
Fujita, D.J.4
Bjorge, J.D.5
Tantiongco, J.P.6
Sotirellis, N.7
Lio, D.S.8
Scholz, G.9
Cheng, H.C.10
-
14
-
-
33749267065
-
C-Src couples PI 3 kinase/Akt and MAPK signalling to PDGF-induced DNA synthesis in mesangial cells
-
Choudhury GG, Mahimainathan L, Das F, Venkatesan B, and Ghosh-Choudhury N. (2006). c-Src couples PI 3 kinase/Akt and MAPK signalling to PDGF-induced DNA synthesis in mesangial cells. Cell Signal 18:1854-1864
-
(2006)
Cell Signal
, vol.18
, pp. 1854-1864
-
-
Choudhury, G.G.1
Mahimainathan, L.2
Das, F.3
Venkatesan, B.4
Ghosh-Choudhury, N.5
-
15
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, Cantley LC. (2008a). The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452:230-233
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
16
-
-
40749099894
-
Pyruvate kinase M2 is a phosphotyrosine- binding protein
-
Christofk HR, Vander Heiden MG, Wu N, Asara JM, and Cantley LC. (2008b). Pyruvate kinase M2 is a phosphotyrosine- binding protein. Nature 452:181-186
-
(2008)
Nature
, vol.452
, pp. 181-186
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
Asara, J.M.4
Cantley, L.C.5
-
17
-
-
0026730817
-
Transcriptional control of nuclear genes for the mitochondrial muscle ADP/ATP translocator and the ATP synthase beta subunit. Multiple factors interact with the OXBOX/ REBOX promoter sequences
-
Chung AB, Stepien G, Haraguchi Y, Li K, Wallace DC. (1992). Transcriptional control of nuclear genes for the mitochondrial muscle ADP/ATP translocator and the ATP synthase beta subunit. Multiple factors interact with the OXBOX/ REBOX promoter sequences. J Biol Chem 267:21154-21161
-
(1992)
J Biol Chem
, vol.267
, pp. 21154-21161
-
-
Chung, A.B.1
Stepien, G.2
Haraguchi, Y.3
Li, K.4
Wallace, D.C.5
-
18
-
-
0037663884
-
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue
-
Cohen AW, Razani B, Wang XB, Combs TP, Williams TM, Scherer PE, Lisanti MP. (2003). Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. Am J Physiol Cell Physiol 285:C222-35.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Cohen, A.W.1
Razani, B.2
Wang, X.B.3
Combs, T.P.4
Williams, T.M.5
Scherer, P.E.6
Lisanti, M.P.7
-
19
-
-
0034141636
-
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo
-
Collins SP, Reoma JL, Gamm DM, Uhler MD. (2000). LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo. Biochem J 345 Pt 3:673-680
-
(2000)
Biochem J
, vol.345
, Issue.PART 3
, pp. 673-680
-
-
Collins, S.P.1
Reoma, J.L.2
Gamm, D.M.3
Uhler, M.D.4
-
20
-
-
7244247059
-
Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development
-
Colognato H, Ramachandrappa S, Olsen IM, ffrench-Constant C. (2004). Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development. J Cell Biol 167:365-375
-
(2004)
J Cell Biol
, vol.167
, pp. 365-375
-
-
Colognato, H.1
Ramachandrappa, S.2
Olsen, I.M.3
Ffrench-Constant, C.4
-
21
-
-
0024751217
-
Expression of a novel form of the fyn proto-oncogene in hematopoietic cells
-
Cooke MP, Perlmutter RM. (1989). Expression of a novel form of the fyn proto-oncogene in hematopoietic cells. New Biol 1:66-74.
-
(1989)
New Biol
, vol.1
, pp. 66-74
-
-
Cooke, M.P.1
Perlmutter, R.M.2
-
22
-
-
0028068882
-
Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure
-
Davies SP, Hawley SA, Woods A, Carling D, Haystead TA, Hardie DG. (1994). Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure. Eur J Biochem 223:351-357
-
(1994)
Eur J Biochem
, vol.223
, pp. 351-357
-
-
Davies, S.P.1
Hawley, S.A.2
Woods, A.3
Carling, D.4
Haystead, T.A.5
Hardie, D.G.6
-
23
-
-
0029561919
-
5-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC
-
Davies SP, Helps NR, Cohen PT, Hardie DG. (1995). 5-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC. FEBS Lett 377:421-425
-
(1995)
FEBS Lett
, vol.377
, pp. 421-425
-
-
Davies, S.P.1
Helps, N.R.2
Cohen, P.T.3
Hardie, D.G.4
-
24
-
-
0030872062
-
Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase
-
Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ. (1997). Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J Biol Chem 272:19125-19132
-
(1997)
J Biol Chem
, vol.272
, pp. 19125-19132
-
-
Della Rocca, G.J.1
Van Biesen, T.2
Daaka, Y.3
Luttrell, D.K.4
Luttrell, L.M.5
Lefkowitz, R.J.6
-
25
-
-
14644427174
-
CD36-dependent fatty acid uptake regulates expression of peroxisome proliferator activated receptors
-
Drover VA, Abumrad NA. (2005). CD36-dependent fatty acid uptake regulates expression of peroxisome proliferator activated receptors. Biochem Soc Trans 33:311-315
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 311-315
-
-
Drover, V.A.1
Abumrad, N.A.2
-
26
-
-
0028805375
-
Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences
-
Ebert BL, Firth JD, Ratcliffe PJ. (1995). Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences. J Biol Chem 270:29083-29089
-
(1995)
J Biol Chem
, vol.270
, pp. 29083-29089
-
-
Ebert, B.L.1
Firth, J.D.2
Ratcliffe, P.J.3
-
27
-
-
2442597072
-
Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny
-
Gadue P, Yin L, Jain S, Stein PL. (2004). Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny. J Immunol 172:6093-6100
-
(2004)
J Immunol
, vol.172
, pp. 6093-6100
-
-
Gadue, P.1
Yin, L.2
Jain, S.3
Stein, P.L.4
-
28
-
-
0036432267
-
Identification of an alternatively spliced isoform of the fyn tyrosine kinase
-
Goldsmith JF, Hall CG, Atkinson TP. (2002). Identification of an alternatively spliced isoform of the fyn tyrosine kinase. Biochem Biophys Res Commun 298:501-504
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 501-504
-
-
Goldsmith, J.F.1
Hall, C.G.2
Atkinson, T.P.3
-
29
-
-
0035542970
-
AMP-activated protein kinase: The energy charge hypothesis revisited
-
Hardie DG, Hawley SA. (2001). AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23:1112-1119
-
(2001)
Bioessays
, vol.23
, pp. 1112-1119
-
-
Hardie, D.G.1
Hawley, S.A.2
-
30
-
-
0033560109
-
AMP-activated protein kinase: An ultrasensitive system for monitoring cellular energy charge
-
Hardie DG, Salt IP, Hawley SA, Davies SP. (1999). AMP-activated protein kinase: An ultrasensitive system for monitoring cellular energy charge. Biochem J 338 (Pt 3):717-722
-
(1999)
Biochem J
, vol.338
, Issue.PART 3
, pp. 717-722
-
-
Hardie, D.G.1
Salt, I.P.2
Hawley, S.A.3
Davies, S.P.4
-
31
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Makela TP, Alessi DR, Hardie DG. (2003). Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2:28.
-
(2003)
J Biol
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
Mustard, K.J.4
Udd, L.5
Makela, T.P.6
Alessi, D.R.7
Hardie, D.G.8
-
32
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley SA, Gadalla AE, Olsen GS, Hardie DG. (2002). The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 51:2420-2425
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
33
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG. (2005). Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2:9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
34
-
-
0028845251
-
5-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase i cascade, via three independent mechanisms
-
Hawley SA, Selbert MA, Goldstein EG, Edelman AM, Carling D, Hardie DG. (1995). 5-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms. J Biol Chem 270:27186-27191
-
(1995)
J Biol Chem
, vol.270
, pp. 27186-27191
-
-
Hawley, S.A.1
Selbert, M.A.2
Goldstein, E.G.3
Edelman, A.M.4
Carling, D.5
Hardie, D.G.6
-
35
-
-
0025775939
-
Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets
-
Huang MM, Bolen JB, Barnwell JW, Shattil SJ, Brugge JS. (1991). Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. Proc Natl Acad Sci USA 88: 7844-7848
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7844-7848
-
-
Huang, M.M.1
Bolen, J.B.2
Barnwell, J.W.3
Shattil, S.J.4
Brugge, J.S.5
-
36
-
-
47649116203
-
Effect of fasting on PPARgamma and AMPK activity in adipocytes
-
Kajita K, Mune T, Ikeda T, Matsumoto M, Uno Y, Sugiyama C, Matsubara K, Morita H, Takemura M, Seishima M, Takeda J, Ishizuka T. (2008). Effect of fasting on PPARgamma and AMPK activity in adipocytes. Diabetes Res Clin Pract 81:144-149
-
(2008)
Diabetes Res Clin Pract
, vol.81
, pp. 144-149
-
-
Kajita, K.1
Mune, T.2
Ikeda, T.3
Matsumoto, M.4
Uno, Y.5
Sugiyama, C.6
Matsubara, K.7
Morita, H.8
Takemura, M.9
Seishima, M.10
Takeda, J.11
Ishizuka, T.12
-
37
-
-
0141925771
-
Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart
-
Kovacic S, Soltys CL, Barr AJ, Shiojima I, Walsh K, Dyck JR. (2003). Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. J Biol Chem 278:39422-39427
-
(2003)
J Biol Chem
, vol.278
, pp. 39422-39427
-
-
Kovacic, S.1
Soltys, C.L.2
Barr, A.J.3
Shiojima, I.4
Walsh, K.5
Dyck, J.R.6
-
38
-
-
56449117024
-
AMPK: A metabolic gauge regulating whole-body energy homeostasis
-
Lage R, Dieguez C, Vidal-Puig A, Lopez M. (2008). AMPK: A metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med 14:539-549
-
(2008)
Trends Mol Med
, vol.14
, pp. 539-549
-
-
Lage, R.1
Dieguez, C.2
Vidal-Puig, A.3
Lopez, M.4
-
39
-
-
1542349837
-
The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: Role in membrane targeting, cell adhesion, and spreading
-
Liang X, Lu Y, Wilkes M, Neubert TA, Resh MD. (2004). The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading. J Biol Chem 279:8133-8139
-
(2004)
J Biol Chem
, vol.279
, pp. 8133-8139
-
-
Liang, X.1
Lu, Y.2
Wilkes, M.3
Neubert, T.A.4
Resh, M.D.5
-
40
-
-
0035903208
-
Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction
-
Liang X, Nazarian A, Erdjument-Bromage H, Bornmann W, Tempst P, Resh MD. (2001). Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. J Biol Chem 276:30987-30994
-
(2001)
J Biol Chem
, vol.276
, pp. 30987-30994
-
-
Liang, X.1
Nazarian, A.2
Erdjument-Bromage, H.3
Bornmann, W.4
Tempst, P.5
Resh, M.D.6
-
41
-
-
0032938716
-
Regulation of tyrosine kinase cascades by G-protein-coupled receptors
-
Luttrell LM, Daaka Y, Lefkowitz RJ. (1999). Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 11:177-183
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 177-183
-
-
Luttrell, L.M.1
Daaka, Y.2
Lefkowitz, R.J.3
-
42
-
-
0030473709
-
Biochemical characterization and deletion analysis of recombinant human protein phosphatase 2C alpha
-
Marley AE, Sullivan JE, Carling D, Abbott WM, Smith GJ, Taylor IW, Carey F, Beri RK. (1996). Biochemical characterization and deletion analysis of recombinant human protein phosphatase 2C alpha. Biochem J 320 (Pt 3):801-806
-
(1996)
Biochem J
, vol.320
, Issue.PART 3
, pp. 801-806
-
-
Marley, A.E.1
Sullivan, J.E.2
Carling, D.3
Abbott, W.M.4
Smith, G.J.5
Taylor, I.W.6
Carey, F.7
Beri, R.K.8
-
43
-
-
0030744872
-
Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
-
Mastick CC, Saltiel AR. (1997). Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. J Biol Chem 272:20706-20714
-
(1997)
J Biol Chem
, vol.272
, pp. 20706-20714
-
-
Mastick, C.C.1
Saltiel, A.R.2
-
44
-
-
28744438683
-
Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia
-
Meex SJ, van der Kallen CJ, van Greevenbroek MM, Eurlings PM, El Hasnaoui M, Evelo CT, Lindsey PJ, Luiken JJ, Glatz JF, de Bruin TW. (2005). Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia. FASEB J 19:2063-2065
-
(2005)
FASEB J
, vol.19
, pp. 2063-2065
-
-
Meex, S.J.1
Van Der Kallen, C.J.2
Van Greevenbroek, M.M.3
Eurlings, P.M.4
El Hasnaoui, M.5
Evelo, C.T.6
Lindsey, P.J.7
Luiken, J.J.8
Glatz, J.F.9
De Bruin, T.W.10
-
45
-
-
33748747706
-
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
-
Momcilovic M, Hong SP, Carlson M. (2006). Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J Biol Chem 281:25336-25343
-
(2006)
J Biol Chem
, vol.281
, pp. 25336-25343
-
-
Momcilovic, M.1
Hong, S.P.2
Carlson, M.3
-
46
-
-
17944387219
-
Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signalling in adipocytes
-
Muller G, Wied S, Frick W. (2000). Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signalling in adipocytes. Mol Cell Biol 20:4708-4723
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4708-4723
-
-
Muller, G.1
Wied, S.2
Frick, W.3
-
47
-
-
0025881470
-
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
-
Nada S, Okada M, MacAuley A, Cooper JA, Nakagawa H. (1991). Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature 351:69-72.
-
(1991)
Nature
, vol.351
, pp. 69-72
-
-
Nada, S.1
Okada, M.2
MacAuley, A.3
Cooper, J.A.4
Nakagawa, H.5
-
48
-
-
0036293394
-
Src family kinase-dependent phosphorylation of a 29-kDa caveolin-associated protein
-
Newcomb LF, Mastick CC. (2002). Src family kinase-dependent phosphorylation of a 29-kDa caveolin-associated protein. Biochem Biophys Res Commun 290:1447-1453
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 1447-1453
-
-
Newcomb, L.F.1
Mastick, C.C.2
-
49
-
-
4344701192
-
Insulin resistance in skeletal muscles of caveolin-3-null mice
-
Oshikawa J, Otsu K, Toya Y, Tsunematsu T, Hankins R, Kawabe J, Minamisawa S, Umemura S, Hagiwara Y, Ishikawa Y. (2004). Insulin resistance in skeletal muscles of caveolin-3-null mice. Proc Natl Acad Sci USA 101:12670-12675
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12670-12675
-
-
Oshikawa, J.1
Otsu, K.2
Toya, Y.3
Tsunematsu, T.4
Hankins, R.5
Kawabe, J.6
Minamisawa, S.7
Umemura, S.8
Hagiwara, Y.9
Ishikawa, Y.10
-
50
-
-
0036347746
-
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
-
Parravicini V, Gadina M, Kovarova M, Odom S, Gonzalez- Espinosa C, Furumoto Y, Saitoh S, Samelson LE, O'Shea JJ, Rivera J. (2002). Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol 3:741-748
-
(2002)
Nat Immunol
, vol.3
, pp. 741-748
-
-
Parravicini, V.1
Gadina, M.2
Kovarova, M.3
Odom, S.4
Gonzalez-Espinosa, C.5
Furumoto, Y.6
Saitoh, S.7
Samelson, L.E.8
O'Shea, J.J.9
Rivera, J.10
-
52
-
-
0037087333
-
Cutting edge: Recruitment of the ancestral fyn gene during emergence of the adaptive immune system
-
Picard C, Gilles A, Pontarotti P, Olive D, Collette Y. (2002). Cutting edge: recruitment of the ancestral fyn gene during emergence of the adaptive immune system. J Immunol 168:2595-2598
-
(2002)
J Immunol
, vol.168
, pp. 2595-2598
-
-
Picard, C.1
Gilles, A.2
Pontarotti, P.3
Olive, D.4
Collette, Y.5
-
53
-
-
0037799908
-
AMPK beta subunit targets metabolic stress sensing to glycogen
-
Polekhina G, Gupta A, Michell BJ, van Denderen B, Murthy S, Feil SC, Jennings IG, Campbell DJ, Witters LA, Parker MW, Kemp BE, Stapleton D. (2003). AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol 13:867-871
-
(2003)
Curr Biol
, vol.13
, pp. 867-871
-
-
Polekhina, G.1
Gupta, A.2
Michell, B.J.3
Van Denderen, B.4
Murthy, S.5
Feil, S.C.6
Jennings, I.G.7
Campbell, D.J.8
Witters, L.A.9
Parker, M.W.10
Kemp, B.E.11
Stapleton, D.12
-
54
-
-
23944518951
-
A SHPing tale: Perspectives on the regulation of SHP-1 and SHP-2 tyrosine phosphatases by the C-terminal tail
-
Poole AW, Jones ML. (2005). A SHPing tale: perspectives on the regulation of SHP-1 and SHP-2 tyrosine phosphatases by the C-terminal tail. Cell Signal 17:1323-1332
-
(2005)
Cell Signal
, vol.17
, pp. 1323-1332
-
-
Poole, A.W.1
Jones, M.L.2
-
55
-
-
0347131011
-
Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension
-
Pravenec M, Landa V, Zidek V, Musilova A, Kazdova L, Qi N, Wang J, St Lezin E, Kurtz TW. (2003). Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. Physiol Res 52:681-688
-
(2003)
Physiol Res
, vol.52
, pp. 681-688
-
-
Pravenec, M.1
Landa, V.2
Zidek, V.3
Musilova, A.4
Kazdova, L.5
Qi, N.6
Wang, J.7
St Lezin, E.8
Kurtz, T.W.9
-
56
-
-
11144238595
-
Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH
-
Rafaeloff-Phail R, Ding L, Conner L, Yeh WK, McClure D, Guo H, Emerson K, Brooks H. (2004). Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH. J Biol Chem 279:52934-52939
-
(2004)
J Biol Chem
, vol.279
, pp. 52934-52939
-
-
Rafaeloff-Phail, R.1
Ding, L.2
Conner, L.3
Yeh, W.K.4
McClure, D.5
Guo, H.6
Emerson, K.7
Brooks, H.8
-
57
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
Roskoski Jr. R. (2005). Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 331:1-14.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1-14
-
-
Roskoski Jr. R1
-
58
-
-
0032529139
-
AMP-activated protein kinase: Greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform
-
Salt I, Celler JW, Hawley SA, Prescot, A, Woods A, Carling D, Hardie DG. (1998). AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. Biochem J 334 (Pt 1):177-187
-
(1998)
Biochem J
, vol.334
, Issue.PART 1
, pp. 177-187
-
-
Salt, I.1
Celler, J.W.2
Hawley, S.A.3
Prescot, A.4
Woods, A.5
Carling, D.6
Hardie, D.G.7
-
59
-
-
0036470213
-
Insulin signalling pathways in time and space
-
Saltiel AR, Pessin JE. (2002). Insulin signalling pathways in time and space. Trends Cell Biol 12:65-71.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 65-71
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
60
-
-
0242268533
-
Insulin signalling in microdomains of the plasma membrane
-
Saltiel AR, Pessin JE. (2003). Insulin signalling in microdomains of the plasma membrane. Traffic 4:711-716.
-
(2003)
Traffic
, vol.4
, pp. 711-716
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
61
-
-
0035375261
-
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP- dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth
-
Sapkota GP, Kieloch A, Lizcano JM, Lain S, Arthur JS, Williams MR, Morrice N, Deak M, Alessi DR. (2001). Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP- dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth. J Biol Chem 276:19469-19482
-
(2001)
J Biol Chem
, vol.276
, pp. 19469-19482
-
-
Sapkota, G.P.1
Kieloch, A.2
Lizcano, J.M.3
Lain, S.4
Arthur, J.S.5
Williams, M.R.6
Morrice, N.7
Deak, M.8
Alessi, D.R.9
-
62
-
-
66849087348
-
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain
-
Sato I, Obata Y, Kasahara K, Nakayama Y, Fukumoto Y, Yamasaki T, Yokoyama KK, Saito T, Yamaguchi N. (2009). Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain. J Cell Sci 122:965-975
-
(2009)
J Cell Sci
, vol.122
, pp. 965-975
-
-
Sato, I.1
Obata, Y.2
Kasahara, K.3
Nakayama, Y.4
Fukumoto, Y.5
Yamasaki, T.6
Yokoyama, K.K.7
Saito, T.8
Yamaguchi, N.9
-
63
-
-
0028243540
-
Role of tyrosine kinases in lymphocyte activation
-
Sefton BM, Taddie JA. (1994). Role of tyrosine kinases in lymphocyte activation. Curr Opin Immunol 6:372-379
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 372-379
-
-
Sefton, B.M.1
Taddie, J.A.2
-
64
-
-
0038522719
-
C-terminal Src kinase (CSK) modulates insulin-like growth factor-I signalling through Src in 3T3-L1 differentiation
-
Sekimoto H, Boney CM. (2003). C-terminal Src kinase (CSK) modulates insulin-like growth factor-I signalling through Src in 3T3-L1 differentiation. Endocrinology 144:2546-2552
-
(2003)
Endocrinology
, vol.144
, pp. 2546-2552
-
-
Sekimoto, H.1
Boney, C.M.2
-
65
-
-
0032938127
-
CD36 antisense expression in 3T3-F442A preadipocytes
-
Sfeir Z, Ibrahimi A, Amri E, Grimaldi P, Abumrad N. (1999). CD36 antisense expression in 3T3-F442A preadipocytes. Mol Cell Biochem 192:3-8.
-
(1999)
Mol Cell Biochem
, vol.192
, pp. 3-8
-
-
Sfeir, Z.1
Ibrahimi, A.2
Amri, E.3
Grimaldi, P.4
Abumrad, N.5
-
66
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. (2000). Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
67
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
Sicheri F, Kuriyan J. (1997). Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 7:777-785
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
68
-
-
0023896220
-
The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase
-
Sim AT, Hardie DG. (1988). The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase. FEBS Lett 233:294-298
-
(1988)
FEBS Lett
, vol.233
, pp. 294-298
-
-
Sim, A.T.1
Hardie, D.G.2
-
69
-
-
0028126820
-
Mammalian 5-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase
-
Stapleton D, Gao G, Michell BJ, Widmer J, Mitchelhill K, Teh T, House CM, Witters LA, Kemp BE. (1994). Mammalian 5-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. J Biol Chem 269:29343-29346
-
(1994)
J Biol Chem
, vol.269
, pp. 29343-29346
-
-
Stapleton, D.1
Gao, G.2
Michell, B.J.3
Widmer, J.4
Mitchelhill, K.5
Teh, T.6
House, C.M.7
Witters, L.A.8
Kemp, B.E.9
-
70
-
-
0027395013
-
A novel Yes-related kinase, Yrk, is expressed at elevated levels in neural and hematopoietic tissues
-
Sudol M, Greulich H, Newman L, Sarkar A, Sukegawa J, Yamamoto T. (1993). A novel Yes-related kinase, Yrk, is expressed at elevated levels in neural and hematopoietic tissues. Oncogene 8:823-831
-
(1993)
Oncogene
, vol.8
, pp. 823-831
-
-
Sudol, M.1
Greulich, H.2
Newman, L.3
Sarkar, A.4
Sukegawa, J.5
Yamamoto, T.6
-
71
-
-
27644500816
-
Requirement of SRC-family tyrosine kinases in fat accumulation
-
Sun Y, Ma YC, Huang J, Chen KY, McGarrigle DK, Huang XY. (2005). Requirement of SRC-family tyrosine kinases in fat accumulation. Biochemistry 44:14455-14462
-
(2005)
Biochemistry
, vol.44
, pp. 14455-14462
-
-
Sun, Y.1
Ma, Y.C.2
Huang, J.3
Chen, K.Y.4
McGarrigle, D.K.5
Huang, X.Y.6
-
72
-
-
0027771186
-
Functional and physical interaction of protein-tyrosine kinases Fyn and Csk in the T-cell signalling system
-
Takeuchi M, Kuramochi S, Fusaki N, Nada S, Kawamura- Tsuzuku J, Matsuda S, Semba K, Toyoshima K, Okada M, Yamamoto T. (1993). Functional and physical interaction of protein-tyrosine kinases Fyn and Csk in the T-cell signalling system. J Biol Chem 268:27413-27419
-
(1993)
J Biol Chem
, vol.268
, pp. 27413-27419
-
-
Takeuchi, M.1
Kuramochi, S.2
Fusaki, N.3
Nada, S.4
Kawamura- Tsuzuku, J.5
Matsuda, S.6
Semba, K.7
Toyoshima, K.8
Okada, M.9
Yamamoto, T.10
-
73
-
-
9144271149
-
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome
-
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. (2003). Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci USA 100:15924-15929
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15924-15929
-
-
Tanaka, T.1
Yamamoto, J.2
Iwasaki, S.3
Asaba, H.4
Hamura, H.5
Ikeda, Y.6
Watanabe, M.7
Magoori, K.8
Ioka, R.X.9
Tachibana, K.10
Watanabe, Y.11
Uchiyama, Y.12
Sumi, K.13
Iguchi, H.14
Ito, S.15
Doi, T.16
Hamakubo, T.17
Naito, M.18
Auwerx, J.19
Yanagisawa, M.20
Kodama, T.21
Sakai, J.22
more..
-
74
-
-
84866476582
-
Rapid plasma membrane anchoring of newly synthesized p59fyn: Selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3
-
van't Hof W, Resh MD. (1997). Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3. J Cell Biol 136:1023-1035
-
(1997)
J Cell Biol
, vol.136
, pp. 1023-1035
-
-
Van'T Hof, W.1
Resh, M.D.2
-
75
-
-
0033815967
-
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods A, Azzout-Marniche D, Foretz M, Stein SC, Lemarchand P, Ferre P, Foufelle F, Carling D. (2000). Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol 20:6704-6711
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
Stein, S.C.4
Lemarchand, P.5
Ferre, P.6
Foufelle, F.7
Carling, D.8
-
76
-
-
0029925785
-
Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro
-
Woods A, Cheung PC, Smith FC, Davison MD, Scott J, Beri RK, Carling D. (1996a). Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro. J Biol Chem 271:10282-10290
-
(1996)
J Biol Chem
, vol.271
, pp. 10282-10290
-
-
Woods, A.1
Cheung, P.C.2
Smith, F.C.3
Davison, M.D.4
Scott, J.5
Beri, R.K.6
Carling, D.7
-
77
-
-
23044437445
-
Ca2+/calmodulin- dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods A, Dickerson K, Heath R, Hong SP, Momcilovic M, Johnstone SR, Carlson M, Carling D. (2005). Ca2+/calmodulin- dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2:21-33.
-
(2005)
Cell Metab
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
78
-
-
0030592623
-
The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro
-
Woods A, Salt I, Scott J, Hardie DG, Carling D. (1996b). The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro. FEBS Lett 397:347-351
-
(1996)
FEBS Lett
, vol.397
, pp. 347-351
-
-
Woods, A.1
Salt, I.2
Scott, J.3
Hardie, D.G.4
Carling, D.5
-
79
-
-
34248199965
-
Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase
-
Wu Y, Song P, Xu J, Zhang M, Zou MH. (2007). Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase. J Biol Chem 282:9777-9788
-
(2007)
J Biol Chem
, vol.282
, pp. 9777-9788
-
-
Wu, Y.1
Song, P.2
Xu, J.3
Zhang, M.4
Zou, M.H.5
-
80
-
-
32044465506
-
TOR signalling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. (2006). TOR signalling in growth and metabolism. Cell 124:471-484
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
81
-
-
33751229931
-
A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
-
Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, Mann DL, Taffet GE, Baldini A, Khoury DS, Schneider MD. (2006). A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci USA 103:17378-17383
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17378-17383
-
-
Xie, M.1
Zhang, D.2
Dyck, J.R.3
Li, Y.4
Zhang, H.5
Morishima, M.6
Mann, D.L.7
Taffet, G.E.8
Baldini, A.9
Khoury, D.S.10
Schneider, M.D.11
-
82
-
-
0034161405
-
A phosphotyrosine displacement mechanism for activation of Src by PTPalpha
-
Zheng XM, Resnick RJ, Shalloway D. (2000). A phosphotyrosine displacement mechanism for activation of Src by PTPalpha. EMBO J 19:964-978
-
(2000)
EMBO J
, vol.19
, pp. 964-978
-
-
Zheng, X.M.1
Resnick, R.J.2
Shalloway, D.3
|