Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes

Biochimica et Biophysica Acta - Biomembranes

Volumn 1788, Issue 9, 2009, Pages 1731-1739

  Sánchez Wandelmer, Jana ^a   Dávalos, Alberto ^a   Herrera, Emilio ^b   Giera, Martin ^c   Cano, Sonia ^a   de la Peña, Gema ^a   Lasunción, Miguel A ^a,d,e   Busto, Rebeca ^a,e  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b UNIVERSIDAD SAN PABLO CEU   (Spain)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF ALCALÁ   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

3T3 L1; Cholesterol biosynthesis; Signal transduction; Sterol

Indexed keywords

CAVEOLIN 1; CHOLESTEROL; GLUCOSE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE FYN;

ANIMAL CELL; ARTICLE; CAVEOLA; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CHOLESTEROL SYNTHESIS; GLUCOSE TRANSPORT; LIPID COMPOSITION; LIPID RAFT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ANIMALS; CAVEOLAE; CAVEOLIN 1; CELL MEMBRANE; CHOLESTEROL; DEHYDROCHOLESTEROLS; ENZYME INHIBITORS; G(M1) GANGLIOSIDE; LANOSTEROL; MEMBRANE MICRODOMAINS; MICE; RECEPTOR, INSULIN; TRANS-1,4-BIS(2-CHLOROBENZAMINOMETHYL)CYCLOHEXANE DIHYDROCHLORIDE; TRIPARANOL;

EID: 68749118353     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2009.05.002     Document Type: Article

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