Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-α

Biochemical Pharmacology

Volumn 77, Issue 7, 2009, Pages 1213-1222

  Hwang, Mun Kyung ^a,b   Kang, Nam Joo ^a,b   Heo, Yong Seok ^b   Lee, Ki Won ^b   Lee, Hyong Joo ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

c Jun N terminal kinase; Cyclooxygenase 2; Delphinidin; Fyn kinase; Tumor necrosis factor

Indexed keywords

CYCLOOXYGENASE 2; DELPHINIDIN; GALLIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN TYROSINE KINASE; RESVERATROL; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BERRY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPIDERMIS CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RED WINE;

ANIMALS; ANTHOCYANINS; BINDING SITES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DRUG DELIVERY SYSTEMS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; PLANTS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-FYN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 61449168794     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.12.021     Document Type: Article

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