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Volumn 68, Issue 14, 2008, Pages 6021-6029

Myricetin suppresses UVB-induced skin cancer by targeting Fyn

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE TRIPHOSPHATE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYRICETIN; PROTEIN KINASE FYN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; ANTINEOPLASTIC AGENT; FLAVONOID; FYN PROTEIN, MOUSE;

EID: 48649090159     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-0899     Document Type: Article
Times cited : (141)

References (45)
  • 1
    • 14644405691 scopus 로고    scopus 로고
    • Cellular and molecular events leading to the development of skin cancer
    • Melnikova VO, Ananthaswamy HN. Cellular and molecular events leading to the development of skin cancer. Mutation research 2005;571:91-106.
    • (2005) Mutation research , vol.571 , pp. 91-106
    • Melnikova, V.O.1    Ananthaswamy, H.N.2
  • 2
    • 0016299016 scopus 로고
    • The wavelengths in sunlight effective in producing skin cancer: A theoretical analysis
    • Setlow RB. The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. Proc Natl Acad Sci U S A 1974;71:3363-6.
    • (1974) Proc Natl Acad Sci U S A , vol.71 , pp. 3363-3366
    • Setlow, R.B.1
  • 3
    • 0027263693 scopus 로고
    • Photoreactivation in humans
    • Ley RD. Photoreactivation in humans. Proc Natl Acad Sci U S A 1993;90:4337.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4337
    • Ley, R.D.1
  • 4
    • 0347157835 scopus 로고    scopus 로고
    • Short-term and long-term cellular and molecular events following UV irradiation of skin: Implications for molecular medicine
    • Matsumura Y, Ananthaswamy HN. Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine. Exp Rev Mol Med 2002;4:1-22.
    • (2002) Exp Rev Mol Med , vol.4 , pp. 1-22
    • Matsumura, Y.1    Ananthaswamy, H.N.2
  • 6
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV-induced signal transduction
    • Bode AM, Dong Z. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE 2003;2003:RE2.
    • (2003) Sci STKE 2003
    • Bode, A.M.1    Dong, Z.2
  • 7
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Ann Rev Biochem 2000;69:145-82.
    • (2000) Ann Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 8
    • 0035963309 scopus 로고    scopus 로고
    • Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes
    • Chen W, Tang Q, Gonzales MS, Bowden GT. Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene 2001;20:3921-6.
    • (2001) Oncogene , vol.20 , pp. 3921-3926
    • Chen, W.1    Tang, Q.2    Gonzales, M.S.3    Bowden, G.T.4
  • 9
    • 0032815072 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis
    • Fischer SM, Lo HH, Gordon GB, et al. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol Carcinog 1999;25:231-40.
    • (1999) Mol Carcinog , vol.25 , pp. 231-240
    • Fischer, S.M.1    Lo, H.H.2    Gordon, G.B.3
  • 11
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • Thomas SM, Brugge JS. Cellular functions regulated by Src family kinases. Ann Rev Cell Dev Biol 1997;13:513-609.
    • (1997) Ann Rev Cell Dev Biol , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 12
    • 0028214877 scopus 로고
    • Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis
    • Cartwright CA, Coad CA, Egbert BM. Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis. J Clin Investig 1994;93:509-15.
    • (1994) J Clin Investig , vol.93 , pp. 509-515
    • Cartwright, C.A.1    Coad, C.A.2    Egbert, B.M.3
  • 13
    • 0036186833 scopus 로고    scopus 로고
    • Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
    • Matsumoto T, Jiang J, Kiguchi K, et al. Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Mol Carcinog 2002;33:146-55.
    • (2002) Mol Carcinog , vol.33 , pp. 146-155
    • Matsumoto, T.1    Jiang, J.2    Kiguchi, K.3
  • 14
    • 0028808080 scopus 로고
    • Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo
    • Muthuswamy SK, Muller WJ. Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo. Oncogene 1995;11:1801-10.
    • (1995) Oncogene , vol.11 , pp. 1801-1810
    • Muthuswamy, S.K.1    Muller, W.J.2
  • 15
    • 0027170840 scopus 로고
    • c-Yes tyrosine kinase activity in human colon carcinoma
    • Park J, Meisler AI, Cartwright CA. c-Yes tyrosine kinase activity in human colon carcinoma. Oncogene 1993;8:2627-35.
    • (1993) Oncogene , vol.8 , pp. 2627-2635
    • Park, J.1    Meisler, A.I.2    Cartwright, C.A.3
  • 16
    • 0029079944 scopus 로고
    • fyn tyrosine kinase is involved in keratinocyte differentiation control
    • Calautti E, Missero C, Stein PL, Ezzell RM, Dotto GP. fyn tyrosine kinase is involved in keratinocyte differentiation control. Genes Dev 1995;9:2279-91.
    • (1995) Genes Dev , vol.9 , pp. 2279-2291
    • Calautti, E.1    Missero, C.2    Stein, P.L.3    Ezzell, R.M.4    Dotto, G.P.5
  • 17
    • 0041940113 scopus 로고    scopus 로고
    • Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis
    • Matsumoto T, Jiang J, Kiguchi K, et al. Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis. Cancer Res 2003;63:4819-28.
    • (2003) Cancer Res , vol.63 , pp. 4819-4828
    • Matsumoto, T.1    Jiang, J.2    Kiguchi, K.3
  • 18
    • 0032211806 scopus 로고    scopus 로고
    • Resh MD. Fyn, a Src family tyrosine kinase. Int J Biochem Cell Biol 1998;30:1159-62.
    • Resh MD. Fyn, a Src family tyrosine kinase. Int J Biochem Cell Biol 1998;30:1159-62.
  • 19
    • 0142211316 scopus 로고    scopus 로고
    • αvβ6-Fyn signaling promotes oral cancer progression
    • Li X, Yang Y, Hu Y, et al. αvβ6-Fyn signaling promotes oral cancer progression. J Biol Chem 2003;278:41646-53.
    • (2003) J Biol Chem , vol.278 , pp. 41646-41653
    • Li, X.1    Yang, Y.2    Hu, Y.3
  • 20
    • 0037033804 scopus 로고    scopus 로고
    • Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion
    • Calautti E, Grossi M, Mammucari C, et al. Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion. J Cell Biol 2002;156:137-48.
    • (2002) J Cell Biol , vol.156 , pp. 137-148
    • Calautti, E.1    Grossi, M.2    Mammucari, C.3
  • 22
    • 0035851913 scopus 로고    scopus 로고
    • EGF-R signaling through Fyn kinase disrupts the function of integrin α6β4 at hemidesmosomes: Role in epithelial cell migration and carcinoma invasion
    • Mariotti A, Kedeshian PA, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG. EGF-R signaling through Fyn kinase disrupts the function of integrin α6β4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol 2001;155:447-58.
    • (2001) J Cell Biol , vol.155 , pp. 447-458
    • Mariotti, A.1    Kedeshian, P.A.2    Dans, M.3    Curatola, A.M.4    Gagnoux-Palacios, L.5    Giancotti, F.G.6
  • 23
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev 2003;3:768-80.
    • (2003) Nat Rev , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 24
    • 0033826684 scopus 로고    scopus 로고
    • The health benefits of wine
    • German JB, Walzem RL. The health benefits of wine. Ann Rev Nutr 2000;20:561-93.
    • (2000) Ann Rev Nutr , vol.20 , pp. 561-593
    • German, J.B.1    Walzem, R.L.2
  • 26
    • 0037063448 scopus 로고    scopus 로고
    • Flavonoids and antioxidant capacity of Georgia-grown Vidalia onions
    • Sellappan S, Akoh CC. Flavonoids and antioxidant capacity of Georgia-grown Vidalia onions. J Agric Food Chem 2002;50:5338-42.
    • (2002) J Agric Food Chem , vol.50 , pp. 5338-5342
    • Sellappan, S.1    Akoh, C.C.2
  • 27
    • 0000661347 scopus 로고    scopus 로고
    • Determination of stilbenes (trans-astringin, cis-and trans-piceid, and cis- and trans-resveratrol) in Portuguese wines
    • Ribeiro de Lima MT, Waffo-Teguo P, Teissedre PL, et al. Determination of stilbenes (trans-astringin, cis-and trans-piceid, and cis- and trans-resveratrol) in Portuguese wines. J Agric Food Chem 1999;47:2666-70.
    • (1999) J Agric Food Chem , vol.47 , pp. 2666-2670
    • Ribeiro de Lima, M.T.1    Waffo-Teguo, P.2    Teissedre, P.L.3
  • 28
    • 34848916118 scopus 로고    scopus 로고
    • Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1
    • Lee KW, Kang NJ, Rogozin EA, et al. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis 2007;28:1918-27.
    • (2007) Carcinogenesis , vol.28 , pp. 1918-1927
    • Lee, K.W.1    Kang, N.J.2    Rogozin, E.A.3
  • 29
    • 0031825424 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascades as regulators of stress responses
    • Karin M. Mitogen-activated protein kinase cascades as regulators of stress responses. Ann N Y Acad Sci 1998;851:139-46.
    • (1998) Ann N Y Acad Sci , vol.851 , pp. 139-146
    • Karin, M.1
  • 30
    • 0034334115 scopus 로고    scopus 로고
    • Signal transduction pathways: Targets for chemoprevention of skin cancer
    • Bode AM, Dong Z. Signal transduction pathways: targets for chemoprevention of skin cancer. Lancet Oncol 2000;1:181-8.
    • (2000) Lancet Oncol , vol.1 , pp. 181-188
    • Bode, A.M.1    Dong, Z.2
  • 31
    • 33745197329 scopus 로고    scopus 로고
    • Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity
    • Ding M, Feng R, Wang SY, et al. Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. J Biol Chem 2006;281:17359-68.
    • (2006) J Biol Chem , vol.281 , pp. 17359-17368
    • Ding, M.1    Feng, R.2    Wang, S.Y.3
  • 32
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995;80:179-85.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 33
    • 4344639798 scopus 로고    scopus 로고
    • Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling
    • Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling. Cancer Res 2004;64:6349-56.
    • (2004) Cancer Res , vol.64 , pp. 6349-6356
    • Mallikarjuna, G.1    Dhanalakshmi, S.2    Singh, R.P.3    Agarwal, C.4    Agarwal, R.5
  • 34
    • 21744443080 scopus 로고    scopus 로고
    • Chemoprevention of skin cancer by grape constituent resveratrol: Relevance to human disease?
    • Aziz MH, Reagan-Shaw S, Wu J, Longley BJ, Ahmad N. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J 2005;19:1193-5.
    • (2005) FASEB J , vol.19 , pp. 1193-1195
    • Aziz, M.H.1    Reagan-Shaw, S.2    Wu, J.3    Longley, B.J.4    Ahmad, N.5
  • 35
    • 0023139824 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols
    • Das M, Khan WA, Asokan P, Bickers DR, Mukhtar H. Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols. Cancer Res 1987;47:767-73.
    • (1987) Cancer Res , vol.47 , pp. 767-773
    • Das, M.1    Khan, W.A.2    Asokan, P.3    Bickers, D.R.4    Mukhtar, H.5
  • 36
    • 0023927609 scopus 로고
    • Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice
    • Mukhtar H, Das M, Khan WA, Wang ZY, Bik DP, Bickers DR. Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice. Cancer Res 1988;48:2361-5.
    • (1988) Cancer Res , vol.48 , pp. 2361-2365
    • Mukhtar, H.1    Das, M.2    Khan, W.A.3    Wang, Z.Y.4    Bik, D.P.5    Bickers, D.R.6
  • 37
    • 0033578305 scopus 로고    scopus 로고
    • Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion
    • Young MR, Li JJ, Rincon M, et al. Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc Natl Acad Sci U S A 1999;96:9827-32.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9827-9832
    • Young, M.R.1    Li, J.J.2    Rincon, M.3
  • 38
    • 0345862188 scopus 로고    scopus 로고
    • Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling
    • Bowden GT. Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat Rev 2004;4:23-35.
    • (2004) Nat Rev , vol.4 , pp. 23-35
    • Bowden, G.T.1
  • 39
    • 13244259472 scopus 로고    scopus 로고
    • Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase
    • He Z, Cho YY, Ma WY, Choi HS, Bode AM, Dong Z. Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase. J Biol Chem 2005;280:2446-54.
    • (2005) J Biol Chem , vol.280 , pp. 2446-2454
    • He, Z.1    Cho, Y.Y.2    Ma, W.Y.3    Choi, H.S.4    Bode, A.M.5    Dong, Z.6
  • 40
    • 0037155158 scopus 로고    scopus 로고
    • Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling
    • Wellbrock C, Weisser C, Geissinger E, Troppmair J, Schartl M. Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling. J Biol Chem 2002;277:6443-54.
    • (2002) J Biol Chem , vol.277 , pp. 6443-6454
    • Wellbrock, C.1    Weisser, C.2    Geissinger, E.3    Troppmair, J.4    Schartl, M.5
  • 41
    • 33847752706 scopus 로고    scopus 로고
    • Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation
    • Li W, Marshall C, Mei L, Gelfand J, Seykora JT. Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation. J Biol Chem 2007;282:1161-9.
    • (2007) J Biol Chem , vol.282 , pp. 1161-1169
    • Li, W.1    Marshall, C.2    Mei, L.3    Gelfand, J.4    Seykora, J.T.5
  • 42
    • 40749163203 scopus 로고    scopus 로고
    • Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation
    • He Z, Tang F, Ermakova S, et al. Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation. Mol Carcinog 2008;47:172-83.
    • (2008) Mol Carcinog , vol.47 , pp. 172-183
    • He, Z.1    Tang, F.2    Ermakova, S.3
  • 43
    • 0035834648 scopus 로고    scopus 로고
    • MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells
    • Zhang Y, Liu G, Dong Z. MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells. J Biol Chem 2001;276:42534-42.
    • (2001) J Biol Chem , vol.276 , pp. 42534-42542
    • Zhang, Y.1    Liu, G.2    Dong, Z.3
  • 44
    • 14044279320 scopus 로고    scopus 로고
    • Srcasm modulates EGF and Src-kinase signaling in keratinocytes
    • Li W, Marshall C, Mei L, et al. Srcasm modulates EGF and Src-kinase signaling in keratinocytes. J Biol Chem 2005;280:6036-46.
    • (2005) J Biol Chem , vol.280 , pp. 6036-6046
    • Li, W.1    Marshall, C.2    Mei, L.3


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