IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase Activities in astroglioma

Journal of Neuro-Oncology

Volumn 109, Issue 2, 2012, Pages 253-260

  Liu, Ying ^a   Jiang, Wenqing ^a   Liu, Jing ^a   Zhao, Shimin ^a   Xiong, Ji ^a   Mao, Ying ^b   Wang, Yin ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Ketoglutarate; Dioxygenase; Glioma; IDH1

Indexed keywords

2 OXOGLUTARIC ACID; 5 HYDROXYMETHYLCYTOSINE; DIOXYGENASE; ENDOSTATIN; GLYCINE DEHYDROGENASE (DECARBOXYLATING); HISTONE H3; LYSINE;

ADULT; ARTICLE; ASTROCYTOMA; CANCER GRADING; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME INHIBITION; FRONTAL LOBE; GENE; GENE LOCATION; GENE MUTATION; GENE PRODUCT; GLIOMA; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN GENOME; HUMAN TISSUE; IDH1 GENE; IDH2 GENE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; PROTEIN EXPRESSION; TUMOR VASCULARIZATION; WILD TYPE;

ADULT; AGED; ANTIGENS, CD34; ASIAN CONTINENTAL ANCESTRY GROUP; ASTROCYTOMA; BRAIN NEOPLASMS; CELL LINE, TRANSFORMED; DIOXYGENASES; DNA METHYLATION; ENDOSTATINS; FEMALE; GLUTAMATES; HUMANS; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; MUTATION; TRANSFECTION;

EID: 84866018949     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-012-0914-4     Document Type: Article

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