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Volumn 34, Issue 44, 2015, Pages 5513-5523

P53, a translational regulator: Contribution to its tumour-suppressor activity

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; PROTEIN P53; RIBOSOME RNA; RNA BINDING PROTEIN; MESSENGER RNA;

EID: 84946498474     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.25     Document Type: Review
Times cited : (70)

References (121)
  • 2
    • 84866425291 scopus 로고    scopus 로고
    • Translational control in cancer etiology
    • Ruggero D. Translational control in cancer etiology. Cold Spring Harbor Perspect Biol 2013; 5: a012336-a012336.
    • (2013) Cold Spring Harbor Perspect Biol , vol.5 , pp. a012336-a012336
    • Ruggero, D.1
  • 3
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • Jackson RJ, Hellen CUT, Pestova TV. The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 2010; 11: 113-127.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.T.2    Pestova, T.V.3
  • 4
    • 84862300106 scopus 로고    scopus 로고
    • Versatility of RNA-binding proteins in cancer
    • Wurth L. Versatility of RNA-binding proteins in cancer. Comp Func Genomics 2012; 2012: 1-11.
    • (2012) Comp Func Genomics , vol.2012 , pp. 1-11
    • Wurth, L.1
  • 7
    • 56649105133 scopus 로고    scopus 로고
    • RNA polymerases i and III, non-coding RNAs and cancer
    • White RJ. RNA polymerases I and III, non-coding RNAs and cancer. Trends Genet 2008; 24: 622-629.
    • (2008) Trends Genet , vol.24 , pp. 622-629
    • White, R.J.1
  • 9
    • 57749187631 scopus 로고    scopus 로고
    • Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
    • Barna M, Pusic A, Zollo O, Costa M, Kondrashov N, Rego E et al. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature 2008; 456: 971-975.
    • (2008) Nature , vol.456 , pp. 971-975
    • Barna, M.1    Pusic, A.2    Zollo, O.3    Costa, M.4    Kondrashov, N.5    Rego, E.6
  • 10
    • 84898739668 scopus 로고    scopus 로고
    • Haematopoietic stem cells require a highly regulated protein synthesis rate
    • Signer RAJ, Magee JA, Salic A, Morrison SJ. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature 2014; 509: 49-54.
    • (2014) Nature , vol.509 , pp. 49-54
    • Signer, R.A.J.1    Magee, J.A.2    Salic, A.3    Morrison, S.J.4
  • 11
    • 84863736613 scopus 로고    scopus 로고
    • Inhibition of RNA polymerase i as a therapeutic strategy to promote cancer-specific activation of p53
    • Bywater MJ, Poortinga G, Sanij E, Hein N, Peck A, Cullinane C et al. Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53. Cancer Cell 2012; 22: 51-65.
    • (2012) Cancer Cell , vol.22 , pp. 51-65
    • Bywater, M.J.1    Poortinga, G.2    Sanij, E.3    Hein, N.4    Peck, A.5    Cullinane, C.6
  • 12
    • 84892409069 scopus 로고    scopus 로고
    • A targeting modality for destruction of RNA polymerase i that possesses anticancer activity
    • Peltonen K, Colis L, Hester L, Trivedi R, Moubarek MS, Moore HM et al. A targeting modality for destruction of RNA polymerase I that possesses anticancer activity. Cancer Cell 2014; 25: 77-90.
    • (2014) Cancer Cell , vol.25 , pp. 77-90
    • Peltonen, K.1    Colis, L.2    Hester, L.3    Trivedi, R.4    Moubarek, M.S.5    Moore, H.M.6
  • 13
    • 84886732942 scopus 로고    scopus 로고
    • Ribosomes: The future of targeted therapies?
    • Marcel V, Catez F, Diaz J-J. Ribosomes: the future of targeted therapies? Oncotarget 2013; 4: 1554-1555.
    • (2013) Oncotarget , vol.4 , pp. 1554-1555
    • Marcel, V.1    Catez, F.2    Diaz, J.-J.3
  • 14
    • 0025173845 scopus 로고
    • P53: Oncogene or anti-oncogene?
    • Lane DP, Benchimol S. p53: oncogene or anti-oncogene? Genes Dev 1990; 4: 1-8.
    • (1990) Genes Dev , vol.4 , pp. 1-8
    • Lane, D.P.1    Benchimol, S.2
  • 16
    • 0021558851 scopus 로고
    • The cellular protein p53 in human tumours
    • Crawford LV, Pim DC, Lamb P. The cellular protein p53 in human tumours. Mol Biol Med 1984; 2: 261-272.
    • (1984) Mol Biol Med , vol.2 , pp. 261-272
    • Crawford, L.V.1    Pim, D.C.2    Lamb, P.3
  • 17
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P et al. Impact of mutant p53 functional properties on TP53mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007; 28: 622-629.
    • (2007) Hum Mutat , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6
  • 18
    • 34047207337 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes
    • Petitjean A, Achatz MIW, Borresen-Dale AL, Hainaut P, Olivier M. TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 2007; 26: 2157-2165.
    • (2007) Oncogene , vol.26 , pp. 2157-2165
    • Petitjean, A.1    Achatz, M.I.W.2    Borresen-Dale, A.L.3    Hainaut, P.4    Olivier, M.5
  • 19
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC, Fraumeni JF, Nelson CE, Kim DH et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990; 250: 1233-1238.
    • (1990) Science , vol.250 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3    Fraumeni, J.F.4    Nelson, C.E.5    Kim, D.H.6
  • 20
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 1990; 348: 747-749.
    • (1990) Nature , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.Q.2    Pirollo, K.3    Blattner, W.4    Chang, E.H.5
  • 21
    • 70350567735 scopus 로고    scopus 로고
    • 20 Years studying p53 functions in genetically engineered mice
    • Donehower LA, Lozano G. 20 Years studying p53 functions in genetically engineered mice. Nat Rev Cancer 2009; 9: 831-841.
    • (2009) Nat Rev Cancer , vol.9 , pp. 831-841
    • Donehower, L.A.1    Lozano, G.2
  • 23
    • 70349442548 scopus 로고    scopus 로고
    • The first 30 years of p53: Growing ever more complex
    • Levine AJ, Oren M. The first 30 years of p53: growing ever more complex. Nat Rev Cancer 2009; 9: 749-758.
    • (2009) Nat Rev Cancer , vol.9 , pp. 749-758
    • Levine, A.J.1    Oren, M.2
  • 24
    • 84899622427 scopus 로고    scopus 로고
    • Unravelling mechanisms of p53-mediated tumour suppresion
    • Bieging KT, Mello SS, Attardi LD. Unravelling mechanisms of p53-mediated tumour suppresion. Nat Rev Cancer 2014; 14: 359-370.
    • (2014) Nat Rev Cancer , vol.14 , pp. 359-370
    • Bieging, K.T.1    Mello, S.S.2    Attardi, L.D.3
  • 25
    • 0346455759 scopus 로고    scopus 로고
    • Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
    • Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK et al. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet 2004; 36: 63-68.
    • (2004) Nat Genet , vol.36 , pp. 63-68
    • Liu, G.1    Parant, J.M.2    Lang, G.3    Chau, P.4    Chavez-Reyes, A.5    El-Naggar, A.K.6
  • 26
    • 84878582588 scopus 로고    scopus 로고
    • P53 DNA binding cooperativity is essential for apoptosis and tumor suppression in vivo
    • Timofeev O, Schlereth K, Wanzel M, Braun A, Nieswandt B, Pagenstecher A et al. p53 DNA binding cooperativity is essential for apoptosis and tumor suppression in vivo. Cell Rep 2013; 3: 1512-1525.
    • (2013) Cell Rep , vol.3 , pp. 1512-1525
    • Timofeev, O.1    Schlereth, K.2    Wanzel, M.3    Braun, A.4    Nieswandt, B.5    Pagenstecher, A.6
  • 27
    • 84878546043 scopus 로고    scopus 로고
    • P53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa
    • Valente LJ, Gray DHD, Michalak EM, Pinon-Hofbauer J, Egle A, Scott CL et al. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa. Cell Rep 2013; 3: 1339-1345.
    • (2013) Cell Rep , vol.3 , pp. 1339-1345
    • Valente, L.J.1    Gray, D.H.D.2    Michalak, E.M.3    Pinon-Hofbauer, J.4    Egle, A.5    Scott, C.L.6
  • 29
    • 84861973567 scopus 로고    scopus 로고
    • Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
    • Li T, Kon N, Jiang Le, Tan M, Ludwig T, Zhao Y et al. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 2012; 149: 1269-1283.
    • (2012) Cell , vol.149 , pp. 1269-1283
    • Li, T.1    Kon, N.2    Jiang Le Tan, M.3    Ludwig, T.4    Zhao, Y.5
  • 30
    • 77955858336 scopus 로고    scopus 로고
    • Posttranslational modification of p53: Cooperative integrators of function
    • Meek DW, Anderson CW. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harbor Perspect Biol 2009; 1: a000950.
    • (2009) Cold Spring Harbor Perspect Biol , vol.1 , pp. a000950
    • Meek, D.W.1    Anderson, C.W.2
  • 31
    • 77954537044 scopus 로고    scopus 로고
    • Regulation of tumor suppressor p53 at the RNA level
    • Vilborg A, Wilhelm MT, Wiman KG. Regulation of tumor suppressor p53 at the RNA level. J Mol Med 2010; 88: 645-652.
    • (2010) J Mol Med , vol.88 , pp. 645-652
    • Vilborg, A.1    Wilhelm, M.T.2    Wiman, K.G.3
  • 32
    • 81155139688 scopus 로고    scopus 로고
    • Biological functions of p53 isoforms through evolution: Lessons from animal and cellular models
    • Marcel V, Dichtel-Danjoy M-L, Sagne C, Hafsi H, Ma D, Ortiz-Cuaran S et al. Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ 2011; 18: 1815-1824.
    • (2011) Cell Death Differ , vol.18 , pp. 1815-1824
    • Marcel, V.1    Dichtel-Danjoy, M.-L.2    Sagne, C.3    Hafsi, H.4    Ma, D.5    Ortiz-Cuaran, S.6
  • 34
    • 59349099726 scopus 로고    scopus 로고
    • P53 isoforms - A conspiracy to kidnap p53 tumor suppressor activity?
    • Marcel V, Hainaut P. p53 isoforms - a conspiracy to kidnap p53 tumor suppressor activity? Cell Mol Life Sci 2008; 66: 391-406.
    • (2008) Cell Mol Life Sci , vol.66 , pp. 391-406
    • Marcel, V.1    Hainaut, P.2
  • 35
    • 84855266512 scopus 로고    scopus 로고
    • Guarding the "translation apparatus" defective ribosome biogenesis and the p53 signaling pathway
    • Chakraborty A, Uechi T, Kenmochi N. Guarding the "translation apparatus": defective ribosome biogenesis and the p53 signaling pathway. WIREs RNA 2011; 2: 507-522.
    • (2011) WIREs RNA , vol.2 , pp. 507-522
    • Chakraborty, A.1    Uechi, T.2    Kenmochi, N.3
  • 36
    • 84890285680 scopus 로고    scopus 로고
    • IRES mediated translational regulation of p53 isoforms
    • Sharathchandra A, Katoch A, Das S. IRES mediated translational regulation of p53 isoforms. WIREs RNA 2013; 5: 131-139.
    • (2013) WIREs RNA , vol.5 , pp. 131-139
    • Sharathchandra, A.1    Katoch, A.2    Das, S.3
  • 37
    • 84905085696 scopus 로고    scopus 로고
    • P53 and ribosome biogenesis stress: The essentials
    • Golomb L, Volarevic S, Oren M. p53 and ribosome biogenesis stress: the essentials. FEBS Lett 2014; 588: 1-9.
    • (2014) FEBS Lett , vol.588 , pp. 1-9
    • Golomb, L.1    Volarevic, S.2    Oren, M.3
  • 38
    • 84861866572 scopus 로고    scopus 로고
    • The mechanics of miRNA-mediated gene silencing: A look under the hood of miRISC
    • Fabian MR, Sonenberg N. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol 2012; 19: 586-593.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 586-593
    • Fabian, M.R.1    Sonenberg, N.2
  • 39
    • 84876318702 scopus 로고    scopus 로고
    • Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation
    • Meijer HA, Kong YW, Lu WT, Wilczynska A, Spriggs RV, Robinson SW et al. Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation. Science 2013; 340: 82-85.
    • (2013) Science , vol.340 , pp. 82-85
    • Meijer, H.A.1    Kong, Y.W.2    Lu, W.T.3    Wilczynska, A.4    Spriggs, R.V.5    Robinson, S.W.6
  • 40
    • 84866423871 scopus 로고    scopus 로고
    • MicroRNAs in the p53 network: Micromanagement of tumour suppression
    • Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 2012; 12: 613-626.
    • (2012) Nat Rev Cancer , vol.12 , pp. 613-626
    • Hermeking, H.1
  • 41
    • 33646258751 scopus 로고    scopus 로고
    • Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer
    • Xi Y. Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer. Clin Cancer Res 2006; 12: 2014-2024.
    • (2006) Clin Cancer Res , vol.12 , pp. 2014-2024
    • Xi, Y.1
  • 43
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of MIR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang T-C, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 2007; 26: 745-752.
    • (2007) Mol Cell , vol.26 , pp. 745-752
    • Chang, T.-C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 44
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447: 1130-1134.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    De Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 46
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MIR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007; 6: 1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6
  • 47
    • 84883644241 scopus 로고    scopus 로고
    • Noncoding RNA in oncogenesis: A new era of identifying key players
    • Deng G, Sui G. Noncoding RNA in oncogenesis: a new era of identifying key players. Int J Mol Sci 2013; 14: 18319-18349.
    • (2013) Int J Mol Sci , vol.14 , pp. 18319-18349
    • Deng, G.1    Sui, G.2
  • 48
    • 84872762772 scopus 로고    scopus 로고
    • The impact of post-transcriptional regulation in the p53 network
    • Freeman JA, Espinosa JM. The impact of post-transcriptional regulation in the p53 network. Brief Func Genomics 2013 12; 46-57.
    • (2013) Brief Func Genomics , vol.12 , pp. 46-57
    • Freeman, J.A.1    Espinosa, J.M.2
  • 49
    • 84887921212 scopus 로고    scopus 로고
    • Identification of new p53 target microRNAs by bioinformatics and functional analysis
    • Bisio A, De Sanctis V, Del Vescovo V, Denti MA, Jegga AG, Inga A et al. Identification of new p53 target microRNAs by bioinformatics and functional analysis. BMC Cancer 2013; 13: 552.
    • (2013) BMC Cancer , vol.13 , pp. 552
    • Bisio, A.1    De Sanctis, V.2    Del Vescovo, V.3    Denti, M.A.4    Jegga, A.G.5    Inga, A.6
  • 51
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang C-J, Chao C-H, Xia W, Yang J-Y, Xiong Y, Li C-W et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 2011; 13: 317-323.
    • (2011) Nat Cell Biol , vol.13 , pp. 317-323
    • Chang, C.-J.1    Chao, C.-H.2    Xia, W.3    Yang, J.-Y.4    Xiong, Y.5    Li, C.-W.6
  • 54
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 2010; 142: 409-419.
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1    Guttman, M.2    Feldser, D.3    Garber, M.4    Koziol, M.J.5    Kenzelmann-Broz, D.6
  • 57
    • 84869090231 scopus 로고    scopus 로고
    • Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis
    • Nikulenkov F, Spinnler C, Li H, Tonelli C, Shi Y, Turunen M et al. Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ 2012; 19: 1992-2002.
    • (2012) Cell Death Differ , vol.19 , pp. 1992-2002
    • Nikulenkov, F.1    Spinnler, C.2    Li, H.3    Tonelli, C.4    Shi, Y.5    Turunen, M.6
  • 58
    • 84883474258 scopus 로고    scopus 로고
    • Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells
    • Menendez D, Nguyen T-A, Freudenberg JM, Mathew VJ, Anderson CW, Jothi R et al. Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells. Nucleic Acids Res 2013; 41: 7286-7301.
    • (2013) Nucleic Acids Res , vol.41 , pp. 7286-7301
    • Menendez, D.1    Nguyen, T.-A.2    Freudenberg, J.M.3    Mathew, V.J.4    Anderson, C.W.5    Jothi, R.6
  • 59
    • 79960424486 scopus 로고    scopus 로고
    • Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas
    • Zhang J, Cho S-J, Shu L, Yan W, Guerrero T, Kent M et al. Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes Dev 2011; 25: 1528-1543.
    • (2011) Genes Dev , vol.25 , pp. 1528-1543
    • Zhang, J.1    Cho, S.-J.2    Shu, L.3    Yan, W.4    Guerrero, T.5    Kent, M.6
  • 60
    • 84930513716 scopus 로고    scopus 로고
    • P53-directed translational control can shape and expand the universe of p53 target genes
    • Zaccara S, Tebaldi T, Pederiva C, Ciribilli Y, Bisio A, Inga A. p53-directed translational control can shape and expand the universe of p53 target genes. Cell Death Differ 2014; 21: 1522-1534.
    • (2014) Cell Death Differ , vol.21 , pp. 1522-1534
    • Zaccara, S.1    Tebaldi, T.2    Pederiva, C.3    Ciribilli, Y.4    Bisio, A.5    Inga, A.6
  • 61
    • 84877879910 scopus 로고    scopus 로고
    • The DEAD box proteins DDX5 (p68) and DDX17 (p72): Multitasking transcriptional regulators
    • Fuller-Pace FV. The DEAD box proteins DDX5 (p68) and DDX17 (p72): multitasking transcriptional regulators. Biochim Biophys Acta 2013; 1829: 756-763.
    • (2013) Biochim Biophys Acta , vol.1829 , pp. 756-763
    • Fuller-Pace, F.V.1
  • 62
    • 84924611001 scopus 로고    scopus 로고
    • Regulation of the mRNA half-life in breast cancer
    • Griseri P. Regulation of the mRNA half-life in breast cancer. World J Clin Oncol 2014; 5: 323.
    • (2014) World J Clin Oncol , vol.5 , pp. 323
    • Griseri, P.1
  • 63
    • 84875229872 scopus 로고    scopus 로고
    • How cells get the message: Dynamic assembly and function of mRNA-protein complex
    • Muller-McNicoll M, Neugebauer KM. How cells get the message: dynamic assembly and function of mRNA-protein complex. Nat Rev Genet 2013; 14: 275-287.
    • (2013) Nat Rev Genet , vol.14 , pp. 275-287
    • Muller-McNicoll, M.1    Neugebauer, K.M.2
  • 64
    • 0027284915 scopus 로고
    • P53-catalyzed annealing of complementary single-stranded nucleic acids
    • Oberosler P, Hloch P, Ramsperger U, Stahl H. p53-catalyzed annealing of complementary single-stranded nucleic acids. EMBO J 1993; 12: 2389-2396.
    • (1993) EMBO J , vol.12 , pp. 2389-2396
    • Oberosler, P.1    Hloch, P.2    Ramsperger, U.3    Stahl, H.4
  • 65
    • 0028915813 scopus 로고
    • Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids
    • Wu L, Bayle JH, Elenbaas B, Pavletich NP, Levine AJ. Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids. Mol Cell Biol 1995; 15: 497-504.
    • (1995) Mol Cell Biol , vol.15 , pp. 497-504
    • Wu, L.1    Bayle, J.H.2    Elenbaas, B.3    Pavletich, N.P.4    Levine, A.J.5
  • 66
    • 33645466699 scopus 로고    scopus 로고
    • Recognition of RNA by the p53 tumor suppressor protein in the yeast three-hybrid system
    • Riley KJL. Recognition of RNA by the p53 tumor suppressor protein in the yeast three-hybrid system. RNA 2006; 12: 620-630.
    • (2006) RNA , vol.12 , pp. 620-630
    • Riley, K.J.L.1
  • 67
    • 34748915767 scopus 로고    scopus 로고
    • Analysis of p53-RNA interactions in cultured human cells
    • Riley KJL, James Maher L III. Analysis of p53-RNA interactions in cultured human cells. Biochem Biophys Res Commun 2007; 363: 381-387.
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 381-387
    • Riley, K.J.L.1    James Maher, L.2
  • 68
    • 35548983482 scopus 로고    scopus 로고
    • P53 RNA interactions: New clues in an old mystery
    • Riley KJL, Maher LJ. p53 RNA interactions: New clues in an old mystery. RNA 2007; 13: 1825-1833.
    • (2007) RNA , vol.13 , pp. 1825-1833
    • Riley, K.J.L.1    Maher, L.J.2
  • 70
    • 0035797499 scopus 로고    scopus 로고
    • P53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA
    • Galy B, Creancier L, Prado-Lourenco L, Prats A-C, Prats H. p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA. Oncogene 2001; 20: 4613-4620.
    • (2001) Oncogene , vol.20 , pp. 4613-4620
    • Galy, B.1    Creancier, L.2    Prado-Lourenco, L.3    Prats, A.-C.4    Prats, H.5
  • 71
    • 0035967104 scopus 로고    scopus 로고
    • Tumour suppressor p53 inhibits human fibroblast growth factor 2 expression by a post-transcriptional mechanism
    • Galy B, Creancier L, Zanibellato C, Prats A-C, Prats H. Tumour suppressor p53 inhibits human fibroblast growth factor 2 expression by a post-transcriptional mechanism. Oncogene 2001; 20: 1669-1677.
    • (2001) Oncogene , vol.20 , pp. 1669-1677
    • Galy, B.1    Creancier, L.2    Zanibellato, C.3    Prats, A.-C.4    Prats, H.5
  • 72
    • 0028981277 scopus 로고
    • P53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest
    • Ewen ME, Oliver CJ, Sluss HK, Miller SJ, Peeper DS. p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest. Genes Dev 1995; 9: 204-217.
    • (1995) Genes Dev , vol.9 , pp. 204-217
    • Ewen, M.E.1    Oliver, C.J.2    Sluss, H.K.3    Miller, S.J.4    Peeper, D.S.5
  • 73
    • 0033756586 scopus 로고    scopus 로고
    • P53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta - And p53-mediated translational inhibition of cdk4
    • Miller SJ, Suthiphongchai T, Zambetti GP, Ewen ME. p53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta - and p53-mediated translational inhibition of cdk4. Mol Cell Biol 2000; 20: 8420-8431.
    • (2000) Mol Cell Biol , vol.20 , pp. 8420-8431
    • Miller, S.J.1    Suthiphongchai, T.2    Zambetti, G.P.3    Ewen, M.E.4
  • 77
    • 84861418314 scopus 로고    scopus 로고
    • Specialized ribosomes: A new frontier in gene regulation and organismal biology
    • Xue S, Barna M. Specialized ribosomes: a new frontier in gene regulation and organismal biology. Nat Rev Mol Cell Biol 2012; 13: 355-369.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 355-369
    • Xue, S.1    Barna, M.2
  • 79
    • 84856236025 scopus 로고    scopus 로고
    • Are snoRNAs and snoRNA host genes new players in cancer?
    • Williams GT, Farzaneh F. Are snoRNAs and snoRNA host genes new players in cancer? Nat Rev Cancer 2012; 12: 84-88.
    • (2012) Nat Rev Cancer , vol.12 , pp. 84-88
    • Williams, G.T.1    Farzaneh, F.2
  • 80
    • 84883634636 scopus 로고    scopus 로고
    • P53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer
    • Marcel V, Ghayad SE, Belin S, Gabriell T, Morel A-P, Solano-Gonzalez E et al. p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer. Cancer Cell 2013; 24: 318-330.
    • (2013) Cancer Cell , vol.24 , pp. 318-330
    • Marcel, V.1    Ghayad, S.E.2    Belin, S.3    Gabriell, T.4    Morel, A.-P.5    Solano-Gonzalez, E.6
  • 81
    • 0037428129 scopus 로고    scopus 로고
    • Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification
    • Ruggero D. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science 2003; 299: 259-262.
    • (2003) Science , vol.299 , pp. 259-262
    • Ruggero, D.1
  • 82
    • 33646543044 scopus 로고    scopus 로고
    • Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita
    • Yoon A, Peng G, Brandenburger Y, Brandenburg Y, Zollo O, Xu W et al. Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science 2006; 312: 902-906.
    • (2006) Science , vol.312 , pp. 902-906
    • Yoon, A.1    Peng, G.2    Brandenburger, Y.3    Brandenburg, Y.4    Zollo, O.5    Xu, W.6
  • 83
    • 84878596830 scopus 로고    scopus 로고
    • H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation
    • Bellodi C, McMahon M, Contreras A, Juliano D, Kopmar N, Nakamura T et al. H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation. Cell Rep 2013; 3: 1493-1502.
    • (2013) Cell Rep , vol.3 , pp. 1493-1502
    • Bellodi, C.1    McMahon, M.2    Contreras, A.3    Juliano, D.4    Kopmar, N.5    Nakamura, T.6
  • 86
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia NT, Ghaemmaghami S, Newman JRS, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 2009; 324: 218-223.
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.S.3    Weissman, J.S.4
  • 87
    • 84876093209 scopus 로고    scopus 로고
    • P53 induces transcriptional and translational programs to suppress cell proliferation and growth
    • Loayza-Puch F, Drost J, Rooijers K, Lopes R, Elkon R, Agami R. p53 induces transcriptional and translational programs to suppress cell proliferation and growth. Genome Biol 2013; 14: R32.
    • (2013) Genome Biol , vol.14 , pp. R32
    • Loayza-Puch, F.1    Drost, J.2    Rooijers, K.3    Lopes, R.4    Elkon, R.5    Agami, R.6
  • 88
    • 0017729820 scopus 로고
    • Continuous protein synthesis is required to maintain the probability of entry into S phase
    • Brooks RF. Continuous protein synthesis is required to maintain the probability of entry into S phase. Cell 1977; 12: 311-317.
    • (1977) Cell , vol.12 , pp. 311-317
    • Brooks, R.F.1
  • 91
    • 10044226056 scopus 로고    scopus 로고
    • Nucleolar size and activity are related to pRb and p53 status in human breast cancer
    • Trere D. Nucleolar size and activity are related to pRb and p53 status in human breast cancer. J Histochem Cytochem 2004; 52: 1601-1607.
    • (2004) J Histochem Cytochem , vol.52 , pp. 1601-1607
    • Trere, D.1
  • 92
    • 0033611568 scopus 로고    scopus 로고
    • P53 represses ribosomal gene transcription
    • Budde A, Grummt I. p53 represses ribosomal gene transcription. Oncogene 1999; 18: 1119-1124.
    • (1999) Oncogene , vol.18 , pp. 1119-1124
    • Budde, A.1    Grummt, I.2
  • 93
    • 0033867975 scopus 로고    scopus 로고
    • Repression of RNA polymerase i transcription by the tumor suppressor p53
    • Zhai W, Comai L. Repression of RNA polymerase I transcription by the tumor suppressor p53. Mol Cell Biol 2000; 20: 5930-5938.
    • (2000) Mol Cell Biol , vol.20 , pp. 5930-5938
    • Zhai, W.1    Comai, L.2
  • 94
    • 0032100624 scopus 로고    scopus 로고
    • P53 is a general repressor of RNA polymerase III transcription
    • Cairns CA, White RJ. p53 is a general repressor of RNA polymerase III transcription. EMBO J 1998; 17: 3112-3123.
    • (1998) EMBO J , vol.17 , pp. 3112-3123
    • Cairns, C.A.1    White, R.J.2
  • 95
    • 0029910713 scopus 로고    scopus 로고
    • P53 inhibits RNA polymerase IIIdirected transcription in a promoter-dependent manner
    • Chesnokov I, Chu WM, Botchan MR, Schmid CW. p53 inhibits RNA polymerase IIIdirected transcription in a promoter-dependent manner. Mol Cell Biol 1996; 16: 7084-7088.
    • (1996) Mol Cell Biol , vol.16 , pp. 7084-7088
    • Chesnokov, I.1    Chu, W.M.2    Botchan, M.R.3    Schmid, C.W.4
  • 96
    • 85047697488 scopus 로고    scopus 로고
    • RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome
    • Stein T, Crighton D, Boyle JM, Varley JM, White RJ. RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome. Oncogene 2002; 21: 2961-2970.
    • (2002) Oncogene , vol.21 , pp. 2961-2970
    • Stein, T.1    Crighton, D.2    Boyle, J.M.3    Varley, J.M.4    White, R.J.5
  • 98
    • 24044529785 scopus 로고    scopus 로고
    • Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53
    • Zhu N, Gu L, Findley HW, Zhou M. Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53. Biochem Biophys Res Commun 2005; 335: 1272-1279.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1272-1279
    • Zhu, N.1    Gu, L.2    Findley, H.W.3    Zhou, M.4
  • 99
    • 0034235630 scopus 로고    scopus 로고
    • Correlation of p53 and the proto-oncogene eIF4E in larynx cancers: Prognostic implications
    • Nathan CA, Sanders K, Abreo FW, Nassar R, Glass J. Correlation of p53 and the proto-oncogene eIF4E in larynx cancers: prognostic implications. Cancer Res 2000; 60: 3599-3604.
    • (2000) Cancer Res , vol.60 , pp. 3599-3604
    • Nathan, C.A.1    Sanders, K.2    Abreo, F.W.3    Nassar, R.4    Glass, J.5
  • 100
    • 2942535833 scopus 로고    scopus 로고
    • Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells
    • Obad S, Brunnstrom H, Vallon-Christersson J, Borg A, Drott K, Gullberg U. Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells. Oncogene 2004; 23: 4050-4059.
    • (2004) Oncogene , vol.23 , pp. 4050-4059
    • Obad, S.1    Brunnstrom, H.2    Vallon-Christersson, J.3    Borg, A.4    Drott, K.5    Gullberg, U.6
  • 101
    • 84864766957 scopus 로고    scopus 로고
    • The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G
    • Petersson J, Ageberg M, Sanden C, Olofsson T, Gullberg U, Drott K. The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G. Biol Cell 2012; 104: 462-475.
    • (2012) Biol Cell , vol.104 , pp. 462-475
    • Petersson, J.1    Ageberg, M.2    Sanden, C.3    Olofsson, T.4    Gullberg, U.5    Drott, K.6
  • 102
    • 0037043851 scopus 로고    scopus 로고
    • P53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation
    • Horton LE, Bushell M, Barth-Baus D, Tilleray VJ, Clemens MJ, Hensold JO. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation. Oncogene 2002; 21: 5325-5334.
    • (2002) Oncogene , vol.21 , pp. 5325-5334
    • Horton, L.E.1    Bushell, M.2    Barth-Baus, D.3    Tilleray, V.J.4    Clemens, M.J.5    Hensold, J.O.6
  • 103
    • 48449101433 scopus 로고    scopus 로고
    • P53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
    • Budanov AV, Karin M. p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 2008; 134: 451-460.
    • (2008) Cell , vol.134 , pp. 451-460
    • Budanov, A.V.1    Karin, M.2
  • 105
    • 33644927797 scopus 로고    scopus 로고
    • Regulation of protein synthesis by inducible wild-type p53 in human lung carcinoma cells
    • Tilleray V, Constantinou C, Clemens MJ. Regulation of protein synthesis by inducible wild-type p53 in human lung carcinoma cells. FEBS Lett 2006; 580: 1766-1770.
    • (2006) FEBS Lett , vol.580 , pp. 1766-1770
    • Tilleray, V.1    Constantinou, C.2    Clemens, M.J.3
  • 106
    • 33847069498 scopus 로고    scopus 로고
    • Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53
    • Constantinou C, Clemens MJ. Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53. Cell Death Differ 2007; 14: 576-585.
    • (2007) Cell Death Differ , vol.14 , pp. 576-585
    • Constantinou, C.1    Clemens, M.J.2
  • 107
    • 66249142352 scopus 로고    scopus 로고
    • The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival
    • Barkic M, Crnomarkovic S, Grabusic K, Bogetic I, Panic L, Tamarut S et al. The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol 2009; 29: 2489-2504.
    • (2009) Mol Cell Biol , vol.29 , pp. 2489-2504
    • Barkic, M.1    Crnomarkovic, S.2    Grabusic, K.3    Bogetic, I.4    Panic, L.5    Tamarut, S.6
  • 108
    • 84872561715 scopus 로고    scopus 로고
    • Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency
    • Donehower LA. Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency. Aging 2012; 4: 660-661.
    • (2012) Aging , vol.4 , pp. 660-661
    • Donehower, L.A.1
  • 109
    • 84872573944 scopus 로고    scopus 로고
    • New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis
    • Comas M, Toshkov I, Kuropatwinski KK, Chernova OB, Polinsky A, Blagosklonny MV et al. New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis. Aging 2012; 4: 715-722.
    • (2012) Aging , vol.4 , pp. 715-722
    • Comas, M.1    Toshkov, I.2    Kuropatwinski, K.K.3    Chernova, O.B.4    Polinsky, A.5    Blagosklonny, M.V.6
  • 111
    • 84902324667 scopus 로고    scopus 로고
    • Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
    • Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA et al. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Elife 2014; 3: e02200.
    • (2014) Elife , vol.3 , pp. e02200
    • Allen, M.A.1    Andrysik, Z.2    Dengler, V.L.3    Mellert, H.S.4    Guarnieri, A.5    Freeman, J.A.6
  • 112
    • 0035843156 scopus 로고    scopus 로고
    • Negative regulation of bcl-2 expression by p53 in hematopoietic cells
    • Wu Y, Mehew JW, Heckman CA, Arcinas M, Boxer LM. Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene 2001; 20: 240-251.
    • (2001) Oncogene , vol.20 , pp. 240-251
    • Wu, Y.1    Mehew, J.W.2    Heckman, C.A.3    Arcinas, M.4    Boxer, L.M.5
  • 113
    • 80053015725 scopus 로고    scopus 로고
    • P53 isoforms: An intracellular microprocessor?
    • Khoury MP, Bourdon J-C. p53 isoforms: an intracellular microprocessor? Genes Cancer 2011; 2: 453-465.
    • (2011) Genes Cancer , vol.2 , pp. 453-465
    • Khoury, M.P.1    Bourdon, J.-C.2
  • 114
    • 69949171557 scopus 로고    scopus 로고
    • P53 isoforms δ133p53 and p53β are endogenous regulators of replicative cellular senescence
    • Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ et al. p53 isoforms δ133p53 and p53β are endogenous regulators of replicative cellular senescence. Nat Cell Biol 2009; 11: 1135-1142.
    • (2009) Nat Cell Biol , vol.11 , pp. 1135-1142
    • Fujita, K.1    Mondal, A.M.2    Horikawa, I.3    Nguyen, G.H.4    Kumamoto, K.5    Sohn, J.J.6
  • 115
    • 84883827546 scopus 로고    scopus 로고
    • The human δnp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function
    • Lin S-C, Karoly ED, Taatjes DJ. The human δNp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. Aging Cell 2013; 12: 863-872.
    • (2013) Aging Cell , vol.12 , pp. 863-872
    • Lin, S.-C.1    Karoly, E.D.2    Taatjes, D.J.3
  • 116
    • 78449297894 scopus 로고    scopus 로고
    • The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network
    • Boominathan L. The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis Rev 2010; 29: 613-639.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 613-639
    • Boominathan, L.1
  • 117
    • 84894122839 scopus 로고    scopus 로고
    • P53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage
    • Cam M, Bid HK, Xiao L, Zambetti GP, Houghton PJ, Cam H. p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage. J Biol Chem 2014; 289: 4083-4094.
    • (2014) J Biol Chem , vol.289 , pp. 4083-4094
    • Cam, M.1    Bid, H.K.2    Xiao, L.3    Zambetti, G.P.4    Houghton, P.J.5    Cam, H.6
  • 118
    • 84861335163 scopus 로고    scopus 로고
    • P63 transcriptionally regulates BNC1 a Pol i and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation
    • Boldrup L, Coates PJ, Laurell G, Nylander K. p63 transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation. Eur J Cancer 2012; 48: 1401-1406.
    • (2012) Eur J Cancer , vol.48 , pp. 1401-1406
    • Boldrup, L.1    Coates, P.J.2    Laurell, G.3    Nylander, K.4
  • 120
    • 84892564905 scopus 로고    scopus 로고
    • Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage
    • Zhang Q, Shalaby NA, Buszczak M. Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage. Science 2014; 343: 298-301.
    • (2014) Science , vol.343 , pp. 298-301
    • Zhang, Q.1    Shalaby, N.A.2    Buszczak, M.3
  • 121
    • 84912104736 scopus 로고    scopus 로고
    • Biosynthesis of ribosomal RNA in nucleoli regulates pluripotency and differentiation ability of pluripotent stem cells
    • Watanabe-Susaki K, Takada H, Enomoto K, Miwata K, Ishimine H, Intoh A et al. Biosynthesis of ribosomal RNA in nucleoli regulates pluripotency and differentiation ability of pluripotent stem cells. Stem Cells 2014; 32: 3099-3111.
    • (2014) Stem Cells , vol.32 , pp. 3099-3111
    • Watanabe-Susaki, K.1    Takada, H.2    Enomoto, K.3    Miwata, K.4    Ishimine, H.5    Intoh, A.6


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