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Volumn 3, Issue 5, 2013, Pages 1512-1525

P53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression InVivo

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GLUTAMIC ACID; PROTEIN P53; TETRAMER; DNA; PROTEIN BINDING;

EID: 84878582588     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.04.008     Document Type: Article
Times cited : (66)

References (47)
  • 5
    • 0035496607 scopus 로고    scopus 로고
    • Rescuing the function of mutant p53
    • Bullock A.N., Fersht A.R. Rescuing the function of mutant p53. Nat. Rev. Cancer 2001, 1:68-76.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 68-76
    • Bullock, A.N.1    Fersht, A.R.2
  • 8
    • 34247860915 scopus 로고    scopus 로고
    • Telomere dysfunction suppresses spontaneous tumorigenesis invivo by initiating p53-dependent cellular senescence
    • Cosme-Blanco W., Shen M.F., Lazar A.J., Pathak S., Lozano G., Multani A.S., Chang S. Telomere dysfunction suppresses spontaneous tumorigenesis invivo by initiating p53-dependent cellular senescence. EMBO Rep. 2007, 8:497-503.
    • (2007) EMBO Rep. , vol.8 , pp. 497-503
    • Cosme-Blanco, W.1    Shen, M.F.2    Lazar, A.J.3    Pathak, S.4    Lozano, G.5    Multani, A.S.6    Chang, S.7
  • 11
    • 34547702285 scopus 로고    scopus 로고
    • Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine
    • Demidov O.N., Timofeev O., Lwin H.N., Kek C., Appella E., Bulavin D.V. Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine. Cell Stem Cell 2007, 1:180-190.
    • (2007) Cell Stem Cell , vol.1 , pp. 180-190
    • Demidov, O.N.1    Timofeev, O.2    Lwin, H.N.3    Kek, C.4    Appella, E.5    Bulavin, D.V.6
  • 12
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C., Zhang P., Harper J.W., Elledge S.J., Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995, 82:675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 16
    • 0028171968 scopus 로고
    • Mediation of c-Myc-induced apoptosis by p53
    • Hermeking H., Eick D. Mediation of c-Myc-induced apoptosis by p53. Science 1994, 265:2091-2093.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 17
    • 77952212178 scopus 로고    scopus 로고
    • Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
    • Hu W., Zhang C., Wu R., Sun Y., Levine A., Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc. Natl. Acad. Sci. USA 2010, 107:7455-7460.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7455-7460
    • Hu, W.1    Zhang, C.2    Wu, R.3    Sun, Y.4    Levine, A.5    Feng, Z.6
  • 24
    • 84861973567 scopus 로고    scopus 로고
    • Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
    • Li T., Kon N., Jiang L., Tan M., Ludwig T., Zhao Y., Baer R., Gu W. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 2012, 149:1269-1283.
    • (2012) Cell , vol.149 , pp. 1269-1283
    • Li, T.1    Kon, N.2    Jiang, L.3    Tan, M.4    Ludwig, T.5    Zhao, Y.6    Baer, R.7    Gu, W.8
  • 26
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe S.W., Ruley H.E., Jacks T., Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993, 74:957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 27
    • 0027319521 scopus 로고
    • P53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe S.W., Schmitt E.M., Smith S.W., Osborne B.A., Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993, 362:847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 29
    • 33845611951 scopus 로고    scopus 로고
    • Modeling the therapeutic efficacy of p53 restoration in tumors
    • Martins C.P., Brown-Swigart L., Evan G.I. Modeling the therapeutic efficacy of p53 restoration in tumors. Cell 2006, 127:1323-1334.
    • (2006) Cell , vol.127 , pp. 1323-1334
    • Martins, C.P.1    Brown-Swigart, L.2    Evan, G.I.3
  • 31
    • 44049095767 scopus 로고    scopus 로고
    • In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
    • Michalak E.M., Villunger A., Adams J.M., Strasser A. In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ. 2008, 15:1019-1029.
    • (2008) Cell Death Differ. , vol.15 , pp. 1019-1029
    • Michalak, E.M.1    Villunger, A.2    Adams, J.M.3    Strasser, A.4
  • 34
    • 84857443702 scopus 로고    scopus 로고
    • The p53 network: cellular and systemic DNA damage responses in aging and cancer
    • Reinhardt H.C., Schumacher B. The p53 network: cellular and systemic DNA damage responses in aging and cancer. Trends Genet. 2012, 28:128-136.
    • (2012) Trends Genet. , vol.28 , pp. 128-136
    • Reinhardt, H.C.1    Schumacher, B.2
  • 37
    • 77958515009 scopus 로고    scopus 로고
    • Life or death: p53-induced apoptosis requires DNA binding cooperativity
    • Schlereth K., Charles J.P., Bretz A.C., Stiewe T. Life or death: p53-induced apoptosis requires DNA binding cooperativity. Cell Cycle 2010, 9:4068-4076.
    • (2010) Cell Cycle , vol.9 , pp. 4068-4076
    • Schlereth, K.1    Charles, J.P.2    Bretz, A.C.3    Stiewe, T.4
  • 39
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 42
    • 33645769536 scopus 로고    scopus 로고
    • A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network
    • Toledo F., Krummel K.A., Lee C.J., Liu C.W., Rodewald L.W., Tang M., Wahl G.M. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network. Cancer Cell 2006, 9:273-285.
    • (2006) Cancer Cell , vol.9 , pp. 273-285
    • Toledo, F.1    Krummel, K.A.2    Lee, C.J.3    Liu, C.W.4    Rodewald, L.W.5    Tang, M.6    Wahl, G.M.7
  • 43
    • 34250315824 scopus 로고    scopus 로고
    • DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model
    • Van Nguyen T., Puebla-Osorio N., Pang H., Dujka M.E., Zhu C. DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model. J.Exp. Med. 2007, 204:1453-1461.
    • (2007) J.Exp. Med. , vol.204 , pp. 1453-1461
    • Van Nguyen, T.1    Puebla-Osorio, N.2    Pang, H.3    Dujka, M.E.4    Zhu, C.5
  • 45
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: the growing complexity of p53
    • Vousden K.H., Prives C. Blinded by the light: the growing complexity of p53. Cell 2009, 137:413-431.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 47
    • 1942520427 scopus 로고    scopus 로고
    • Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses
    • Yoon K.A., Nakamura Y., Arakawa H. Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses. J.Hum. Genet. 2004, 49:134-140.
    • (2004) J.Hum. Genet. , vol.49 , pp. 134-140
    • Yoon, K.A.1    Nakamura, Y.2    Arakawa, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.