P53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

Cell Reports

Volumn 3, Issue 5, 2013, Pages 1339-1345

  Valente, Liz J ^a,b   Gray, Daniel H D ^a,b   Michalak, Ewa M ^a,b   Pinon Hofbauer, Josefina ^c   Egle, Alex ^c   Scott, Clare L ^a,b   Janic, Ana ^a,b   Strasser, Andreas ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2AX; PROTEIN NOXA; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; APOPTOSIS REGULATORY PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PMAIP1 PROTEIN, MOUSE; PROTEIN BCL 2; PUMA PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CELL AGING; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; G1 PHASE CELL CYCLE CHECKPOINT; GENE TARGETING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DEFICIENCY; GAMMA RADIATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; RADIATION RESPONSE; S PHASE CELL CYCLE CHECKPOINT; THYMOCYTE;

ANIMALIA; MUS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA REPAIR; G1 PHASE CELL CYCLE CHECKPOINTS; GAMMA RAYS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-BCL-2; S PHASE CELL CYCLE CHECKPOINTS; THYMOCYTES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84878546043     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.04.012     Document Type: Article

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