Biosynthesis of ribosomal RNA in nucleoli regulates pluripotency and differentiation ability of pluripotent stem cells

Stem Cells

Volumn 32, Issue 12, 2014, Pages 3099-3111

  Watanabe Susaki, Kanako ^a   Takada, Hitomi ^a   Enomoto, Kei ^b   Miwata, Kyoko ^a   Ishimine, Hisako ^a   Intoh, Atsushi ^b   Ohtaka, Manami ^a   Nakanishi, Mahito ^a   Sugino, Hiromu ^a   Asashima, Makoto ^a,b,c,d   Kurisaki, Akira ^a,d  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Differentiation; Embryonic stem cells; Fibrillarin; Nucleoli; Pluripotency; Ribosomal RNA

Indexed keywords

ALKALINE PHOSPHATASE; DACTINOMYCIN; FIBRILLARIN; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; METHYLTRANSFERASE; OCTAMER TRANSCRIPTION FACTOR 4; RIBOSOME RNA; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DELETION MUTANT; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; RNA SYNTHESIS; STABLE EXPRESSION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; MOUSE EMBRYONIC STEM CELL; NUCLEOLUS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL NUCLEOLUS; CELLS, CULTURED; LEUKEMIA INHIBITORY FACTOR; MICE; MOUSE EMBRYONIC STEM CELLS; PLURIPOTENT STEM CELLS; RNA, RIBOSOMAL; SIGNAL TRANSDUCTION;

EID: 84912104736     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1825     Document Type: Article

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