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Volumn 25, Issue 1, 2014, Pages 77-90

A targeting modality for destruction of RNA polymerase I that possesses anticancer activity

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE; PROTEASOME; PROTEIN P53; RIBOSOME DNA; SMALL MOLECULE TRANSPORT AGENT; SMALL MOLECULE TRANSPORT AGENT BMH 21; UNCLASSIFIED DRUG;

EID: 84892409069     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.12.009     Document Type: Article
Times cited : (214)

References (58)
  • 4
    • 0033611568 scopus 로고    scopus 로고
    • P53 represses ribosomal gene transcription
    • Budde A., Grummt I. p53 represses ribosomal gene transcription. Oncogene 1999, 18:1119-1124.
    • (1999) Oncogene , vol.18 , pp. 1119-1124
    • Budde, A.1    Grummt, I.2
  • 7
    • 84876884110 scopus 로고    scopus 로고
    • Dysregulation of the basal RNA polymerase transcription apparatus in cancer
    • Bywater M.J., Pearson R.B., McArthur G.A., Hannan R.D. Dysregulation of the basal RNA polymerase transcription apparatus in cancer. Nat. Rev. Cancer 2013, 13:299-314.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 299-314
    • Bywater, M.J.1    Pearson, R.B.2    McArthur, G.A.3    Hannan, R.D.4
  • 10
    • 1242296369 scopus 로고    scopus 로고
    • Mechanism of RNA polymerase I transcription
    • Comai L. Mechanism of RNA polymerase I transcription. Adv. Protein Chem. 2004, 67:123-155.
    • (2004) Adv. Protein Chem. , vol.67 , pp. 123-155
    • Comai, L.1
  • 17
    • 0028063847 scopus 로고
    • Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil
    • Ghoshal K., Jacob S.T. Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil. Cancer Res. 1994, 54:632-636.
    • (1994) Cancer Res. , vol.54 , pp. 632-636
    • Ghoshal, K.1    Jacob, S.T.2
  • 18
    • 43449111772 scopus 로고    scopus 로고
    • Modulation of RNA polymerase assembly dynamics in transcriptional regulation
    • Gorski S.A., Snyder S.K., John S., Grummt I., Misteli T. Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol. Cell 2008, 30:486-497.
    • (2008) Mol. Cell , vol.30 , pp. 486-497
    • Gorski, S.A.1    Snyder, S.K.2    John, S.3    Grummt, I.4    Misteli, T.5
  • 19
    • 78049261451 scopus 로고    scopus 로고
    • Wisely chosen paths-regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
    • Grummt I. Wisely chosen paths-regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden. FEBS J. 2010, 277:4626-4639.
    • (2010) FEBS J. , vol.277 , pp. 4626-4639
    • Grummt, I.1
  • 20
    • 37349029690 scopus 로고    scopus 로고
    • RNA polymerase I: a multifunctional molecular machine
    • Haag J.R., Pikaard C.S. RNA polymerase I: a multifunctional molecular machine. Cell 2007, 131:1224-1225.
    • (2007) Cell , vol.131 , pp. 1224-1225
    • Haag, J.R.1    Pikaard, C.S.2
  • 22
    • 0017283713 scopus 로고
    • The carcinogenicity of anticancer drugs: a hazard in man
    • Harris C.C. The carcinogenicity of anticancer drugs: a hazard in man. Cancer 1976, 37(2, Suppl):1014-1023.
    • (1976) Cancer , vol.37 , Issue.2 SUPPL , pp. 1014-1023
    • Harris, C.C.1
  • 23
    • 30044434446 scopus 로고    scopus 로고
    • Nucleolus: from structure to dynamics
    • Hernandez-Verdun D. Nucleolus: from structure to dynamics. Histochem. Cell Biol. 2006, 125:127-137.
    • (2006) Histochem. Cell Biol. , vol.125 , pp. 127-137
    • Hernandez-Verdun, D.1
  • 25
    • 76249101086 scopus 로고    scopus 로고
    • Abundance of ribosomal RNA gene copies maintains genome integrity
    • Ide S., Miyazaki T., Maki H., Kobayashi T. Abundance of ribosomal RNA gene copies maintains genome integrity. Science 2010, 327:693-696.
    • (2010) Science , vol.327 , pp. 693-696
    • Ide, S.1    Miyazaki, T.2    Maki, H.3    Kobayashi, T.4
  • 27
    • 2342491487 scopus 로고    scopus 로고
    • Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation
    • Kurki S., Peltonen K., Latonen L., Kiviharju T.M., Ojala P.M., Meek D., Laiho M. Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation. Cancer Cell 2004, 5:465-475.
    • (2004) Cancer Cell , vol.5 , pp. 465-475
    • Kurki, S.1    Peltonen, K.2    Latonen, L.3    Kiviharju, T.M.4    Ojala, P.M.5    Meek, D.6    Laiho, M.7
  • 29
    • 0035824818 scopus 로고    scopus 로고
    • Regulation of ribosome biogenesis within the nucleolus
    • Leary D.J., Huang S. Regulation of ribosome biogenesis within the nucleolus. FEBS Lett. 2001, 509:145-150.
    • (2001) FEBS Lett. , vol.509 , pp. 145-150
    • Leary, D.J.1    Huang, S.2
  • 31
    • 61449182121 scopus 로고    scopus 로고
    • Principles of cancer therapy: oncogene and non-oncogene addiction
    • Luo J., Solimini N.L., Elledge S.J. Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 2009, 136:823-837.
    • (2009) Cell , vol.136 , pp. 823-837
    • Luo, J.1    Solimini, N.L.2    Elledge, S.J.3
  • 32
    • 38149141767 scopus 로고    scopus 로고
    • Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis
    • Maclean K.H., Dorsey F.C., Cleveland J.L., Kastan M.B. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. J.Clin. Invest. 2008, 118:79-88.
    • (2008) J.Clin. Invest. , vol.118 , pp. 79-88
    • Maclean, K.H.1    Dorsey, F.C.2    Cleveland, J.L.3    Kastan, M.B.4
  • 33
    • 1542343973 scopus 로고    scopus 로고
    • MTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability
    • Mayer C., Zhao J., Yuan X., Grummt I. mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev. 2004, 18:423-434.
    • (2004) Genes Dev. , vol.18 , pp. 423-434
    • Mayer, C.1    Zhao, J.2    Yuan, X.3    Grummt, I.4
  • 34
    • 55849109584 scopus 로고    scopus 로고
    • The epigenetics of rRNA genes: from molecular to chromosome biology
    • McStay B., Grummt I. The epigenetics of rRNA genes: from molecular to chromosome biology. Annu. Rev. Cell Dev. Biol. 2008, 24:131-157.
    • (2008) Annu. Rev. Cell Dev. Biol. , vol.24 , pp. 131-157
    • McStay, B.1    Grummt, I.2
  • 35
    • 43249097755 scopus 로고    scopus 로고
    • Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules
    • Merz K., Hondele M., Goetze H., Gmelch K., Stoeckl U., Griesenbeck J. Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules. Genes Dev. 2008, 22:1190-1204.
    • (2008) Genes Dev. , vol.22 , pp. 1190-1204
    • Merz, K.1    Hondele, M.2    Goetze, H.3    Gmelch, K.4    Stoeckl, U.5    Griesenbeck, J.6
  • 40
    • 57549100234 scopus 로고    scopus 로고
    • Assays for ribosomal RNA processing and ribosome assembly
    • Chapter 22:Unit 22.11
    • Pestov D.G., Lapik Y.R., Lau L.F. Assays for ribosomal RNA processing and ribosome assembly. Curr. Protoc. Cell Biol. 2008, Chapter 22:Unit 22.11.
    • (2008) Curr. Protoc. Cell Biol.
    • Pestov, D.G.1    Lapik, Y.R.2    Lau, L.F.3
  • 42
    • 0344011603 scopus 로고    scopus 로고
    • Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
    • Rubbi C.P., Milner J. Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses. EMBO J. 2003, 22:6068-6077.
    • (2003) EMBO J. , vol.22 , pp. 6068-6077
    • Rubbi, C.P.1    Milner, J.2
  • 43
    • 0037363075 scopus 로고    scopus 로고
    • Does the ribosome translate cancer?
    • Ruggero D., Pandolfi P.P. Does the ribosome translate cancer?. Nat. Rev. Cancer 2003, 3:179-192.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 179-192
    • Ruggero, D.1    Pandolfi, P.P.2
  • 44
    • 33646847147 scopus 로고    scopus 로고
    • The RNA polymerase I transcription machinery
    • Russell J., Zomerdijk J.C. The RNA polymerase I transcription machinery. Biochem. Soc. Symp. 2006, 73:203-216.
    • (2006) Biochem. Soc. Symp. , vol.73 , pp. 203-216
    • Russell, J.1    Zomerdijk, J.C.2
  • 45
    • 73449096759 scopus 로고    scopus 로고
    • The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin
    • Sanij E., Hannan R.D. The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin. Epigenetics 2009, 4:374-382.
    • (2009) Epigenetics , vol.4 , pp. 374-382
    • Sanij, E.1    Hannan, R.D.2
  • 47
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker R.H. The NCI60 human tumour cell line anticancer drug screen. Nat. Rev. Cancer 2006, 6:813-823.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 48
    • 79953158399 scopus 로고    scopus 로고
    • Exploring the genomes of cancer cells: progress and promise
    • Stratton M.R. Exploring the genomes of cancer cells: progress and promise. Science 2011, 331:1553-1558.
    • (2011) Science , vol.331 , pp. 1553-1558
    • Stratton, M.R.1
  • 49
    • 0037291204 scopus 로고    scopus 로고
    • Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
    • Sugimoto M., Kuo M.L., Roussel M.F., Sherr C.J. Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. Mol. Cell 2003, 11:415-424.
    • (2003) Mol. Cell , vol.11 , pp. 415-424
    • Sugimoto, M.1    Kuo, M.L.2    Roussel, M.F.3    Sherr, C.J.4
  • 50
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott O., Olson A.J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J.Comput. Chem. 2010, 31:455-461.
    • (2010) J.Comput. Chem. , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 51
    • 1642576322 scopus 로고    scopus 로고
    • A fluorescent intercalator displacement assay for establishing DNA binding selectivity and affinity
    • Tse W.C., Boger D.L. A fluorescent intercalator displacement assay for establishing DNA binding selectivity and affinity. Acc. Chem. Res. 2005, 37:61-69.
    • (2005) Acc. Chem. Res. , vol.37 , pp. 61-69
    • Tse, W.C.1    Boger, D.L.2
  • 53
    • 67649217159 scopus 로고    scopus 로고
    • Inhibiting the transcription factor HSF1 as an anticancer strategy
    • Whitesell L., Lindquist S. Inhibiting the transcription factor HSF1 as an anticancer strategy. Expert Opin. Ther. Targets 2009, 13:469-478.
    • (2009) Expert Opin. Ther. Targets , vol.13 , pp. 469-478
    • Whitesell, L.1    Lindquist, S.2
  • 54
    • 70350734808 scopus 로고    scopus 로고
    • Preparation of synchronized human cell extracts to study ubiquitination and degradation
    • Williamson A., Jin L., Rape M. Preparation of synchronized human cell extracts to study ubiquitination and degradation. Methods Mol. Biol. 2009, 545:301-312.
    • (2009) Methods Mol. Biol. , vol.545 , pp. 301-312
    • Williamson, A.1    Jin, L.2    Rape, M.3
  • 55
    • 84872414012 scopus 로고    scopus 로고
    • Ubiquitylation and degradation of elongating RNA polymerase II: the last resort
    • Wilson M.D., Harreman M., Svejstrup J.Q. Ubiquitylation and degradation of elongating RNA polymerase II: the last resort. Biochim. Biophys. Acta 2013, 1829:151-157.
    • (2013) Biochim. Biophys. Acta , vol.1829 , pp. 151-157
    • Wilson, M.D.1    Harreman, M.2    Svejstrup, J.Q.3
  • 57
    • 0033867975 scopus 로고    scopus 로고
    • Repression of RNA polymerase I transcription by the tumor suppressor p53
    • Zhai W., Comai L. Repression of RNA polymerase I transcription by the tumor suppressor p53. Mol. Cell. Biol. 2000, 20:5930-5938.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5930-5938
    • Zhai, W.1    Comai, L.2
  • 58
    • 70350497397 scopus 로고    scopus 로고
    • Signaling to p53: ribosomal proteins find their way
    • Zhang Y., Lu H. Signaling to p53: ribosomal proteins find their way. Cancer Cell 2009, 16:369-377.
    • (2009) Cancer Cell , vol.16 , pp. 369-377
    • Zhang, Y.1    Lu, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.