Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita

Science

Volumn 312, Issue 5775, 2006, Pages 902-906

  Yoon, Andrew ^a   Peng, Guang ^a   Brandenburg, Yves ^a   Zollo, Ornella ^a   Xu, Wei ^a   Rego, Eduardo ^b   Ruggero, Davide ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; DISEASES; ENZYMES; MUTAGENESIS; RNA; TUMORS;

APOPTOSIS PROTEIN; DYSKERATOSIS CONGENITA; RIBOSOMAL RNA (RRNA); RIBOSOME MODIFICATION;

GENETIC ENGINEERING;

CYCLIN DEPENDENT KINASE INHIBITOR 1B; MESSENGER RNA; PROTEIN BCL XL; RIBOSOME RNA; VIRUS VECTOR; X LINKED INHIBITOR OF APOPTOSIS;

CANCER; MUTATION; RNA; SKIN DISORDER; TUMOR;

ANIMAL CELL; ARTICLE; BONE MARROW DEPRESSION; CANCER; CANCER SUSCEPTIBILITY; CONGENITAL SKIN DISEASE; DKC1 GENE; DYSKERATOSIS CONGENITA; EMBRYO; FIBROBLAST; GENE; GENE MUTATION; INTERNAL RIBOSOME ENTRY SITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; RIBOSOME; RNA TRANSLATION; X CHROMOSOME LINKED DISORDER;

5' UNTRANSLATED REGIONS; ANIMALS; BCL-X PROTEIN; CELL CYCLE PROTEINS; CELL LINE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DYSKERATOSIS CONGENITA; HUMANS; INSECT VIRUSES; LYMPHOCYTES; MALE; MICE; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POINT MUTATION; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; PROTEOMICS; PSEUDOURIDINE; RNA VIRUSES; RNA, MESSENGER; RNA, RIBOSOMAL; TRANSFECTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 33646543044     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1123835     Document Type: Article

References (31)

1. I. Dokal, Br. J. Haematol. 110, 768 (2000).
2. U. T. Meier, Chromosoma 114, 1 (2005).
3. J. Ni, A. L. Tien, M. J. Fournier, Cell 89, 565 (1997).
4. C. Wang, C. C. Query, U. T. Meier, Mol. Cell. Biol. 22, 8457 (2002).
5. Y. Mochizuki, J. He, S. Kulkarni, M. Bessler, P. J. Mason, Proc. Natl. Acad. Sci. U.S.A. 101, 10756 (2004).
6. D. Ruggero et al., Science 299, 259 (2003).
7. Materials and methods are available as supporting material on Science Online.
8. N. A. Gasper, C. C. Petty, L. W. Schrum, I. Marriott, K. L. Bost, Infect. Immun. 70, 4075 (2002).
9. V. Sharma, M. Delgado, D. Ganea, J. Immunol. 176, 97 (2006).
10. A. J. Stauber et al., Mol. Pharmacol. 67, 681 (2005).
11. M. Holcik, C. Lefebvre, C. Yeh, T. Chow, R. G. Korneluk, Nat. Cell Biol. 1, 190 (1999).
12. W. K. Miskimins, G. Wang, M. Hawkinson, R. Miskimins, Mol. Cell. Biol. 21, 4960 (2001).
13. M. Kullmann, U. Gopfert, B. Siewe, L. Hengst, Genes Dev. 16, 3087 (2002).
14. C. U. Hellen, P. Sarnow, Genes Dev. 15, 1593 (2001).
15. M. Holcik, N. Sonenberg, Nat. Rev. Mol. Cell Biol. 6, 318 (2005).
16. S. S. Millard et al., J. Biol. Chem. 272, 7093 (1997).
17. J. Pelletier, N. Sonenberg, J. Virol. 63, 441 (1989).
18. M. Stoneley, F. E. Paulin, J. P. Le Quesne, S. A. Chappell, A. E. Willis, Oncogene 16, 423 (1998).
19. S. Cho, J. H. Kim, S. H. Back, S. K. Jang, Mol. Cell. Biol. 25, 1283 (2005).
20. M. L. Fero, E. Randel, K. E. Gurley, J. M. Roberts, C. J. Kemp, Nature 396, 177 (1998).
21. J. Philipp-Staheli, S. R. Payne, C. J. Kemp, Exp. Cell Res. 264, 148 (2001).
22. M. L. Fero et al., Cell 85, 733 (1996).
23. H. Kiyokawa et al., Cell 85, 721 (1996).
24. K. Nakayama et al., Cell 85, 707 (1996).
25. J. E. Wilson, T. V. Pestova, C. U. Hellen, P. Sarnow, Cell 102, 511 (2000).
26. E. Jan, P. Sarnow, J. Mol. Biol. 324, 889 (2002).
27. C. P. Petersen, M. E. Bordeleau, J. Pelletier, P. A. Sharp, Mol. Cell 21, 533 (2006).
28. I. Dokal, Curr. Opin. Hematol. 3, 453 (1996).
29. N. Motoyama et al., Science 267, 1506 (1995).
30. M. Socolovsky, A. E. Fallon, S. Wang, C. Brugnara, H. F. Lodish, Cell 98, 181 (1999).
31. -/- mice; M. Holcik, L. Hengst, and P. Sarnow for reagents; K. Zaret, J. Burch, E. Golemis, and J. Testa for critical reading of the manuscript; and FCCC core facilities and J. Grant for technical assistance.