The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G

Biology of the Cell

Volumn 104, Issue 8, 2012, Pages 462-475

  Petersson, Jessica ^a   Ageberg, Malin ^a   Sandén, Carl ^a   Olofsson, Tor ^a   Gullberg, Urban ^a   Drott, Kristina ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

IFN; P53; PML; Translation; TRIM22

Indexed keywords

CAP BINDING PROTEIN; CHEMOKINE; INITIATION FACTOR 4E; INITIATION FACTOR 4G; INTERFERON; LUCIFERASE; MESSENGER RNA; METHIONINE; PROTEIN P53; TRIPARTITE MOTIF PROTEIN 22; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DEATH; CELL GROWTH; CELL STRAIN U937; CLONOGENESIS; CONTROLLED STUDY; DATA ANALYSIS; EUKARYOTE; GENE; GENE EXPRESSION; GENE INTERACTION; HUMAN; HUMAN CELL; ISOTOPE LABELING; PRIORITY JOURNAL; PROTEIN ASSEMBLY; TRANSLATION INITIATION; TRIM22 GENE;

EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4G; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INTERFERON REGULATORY FACTOR-7; INTERFERONS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EUKARYOTA;

EID: 84864766957     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1111/boc.201100099     Document Type: Article

References (48)

1. Asnaghi, L., Bruno, P., Priulla, M. and Nicolin, A. (2004) mTOR: a protein kinase switching between life and death. Pharmacol. Res. 50, 545-549
2. Barr, S.D., Smiley, J.R. and Bushman, F.D. (2008) The interferon response inhibits HIV particle production by induction of TRIM22. PLoS Pathog. 4, e1000007
3. Bouazzaoui, A., Kreutz, M., Eisert, V., Dinauer, N., Heinzelmann, A., Hallenberger, S., Strayle, J., Walker, R., Rubsamen-Waigmann, H., Andreesen, R. and von Briesen, H. (2006) Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages. Virology 356, 79-94
4. Cao, T., Duprez, E., Borden, K.L., Freemont, P.S. and Etkin, L.D. (1998) Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML. J. Cell Sci. 111, 1319-1329
5. Cao, T., Shannon, M., Handel, M.A. and Etkin, L.D. (1996) Mouse ret finger protein (rfp) proto-oncogene is expressed at specific stages of mouse spermatogenesis. Dev. Genet. 19, 309-320
6. Carthagena, L., Bergamaschi, A., Luna, J.M., David, A., Uchil, P.D., Margottin-Goguet, F., Mothes, W., Hazan, U., Transy, C., Pancino, G. and Nisole, S. (2009) Human TRIM gene expression in response to interferons. PLoS One 4, e4894
7. Cencic, R., Desforges, M., Hall, D.R., Kozakov, D., Du, Y., Min, J., Dingledine, R., Fu, H., Vajda, S., Talbot, P.J. and Pelletier, J. (2011) Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J. Virol. 85, 6381-6389
8. Cohen, N., Sharma, M., Kentsis, A., Perez, J.M., Strudwick, S. and Borden, K.L. (2001) PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA. EMBO J. 20, 4547-4559
9. Colina, R., Costa-Mattioli, M., Dowling, R.J., Jaramillo, M., Tai, L.H., Breitbach, C.J., Martineau, Y., Larsson, O., Rong, L., Svitkin, Y.V., Makrigiannis, A.P., Bell, J.C. and Sonenberg, N. (2008) Translational control of the innate immune response through IRF-7. Nature 452, 323-328
10. Constantinou, C. and Clemens, M.J. (2007) Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53. Cell Death Differ. 14, 576-585
11. Culjkovic, B., Topisirovic, I., Skrabanek, L., Ruiz-Gutierrez, M. and Borden, K.L. (2006) eIF4E is a central node of an RNA regulon that governs cellular proliferation. J. Cell Biol. 175, 415-426
12. De Benedetti, A. and Baglioni, C. (1984) Inhibition of mRNA binding to ribosomes by localized activation of dsRNA-dependent protein kinase. Nature 311, 79-81
13. de Stanchina, E., Querido, E., Narita, M., Davuluri, R.V., Pandolfi, P.P., Ferbeyre, G. and Lowe, S.W. (2004) PML is a direct p53 target that modulates p53 effector functions. Mol. Cell 13, 523-535
14. Der, S.D. and Lau, A.S. (1995) Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity. Proc. Natl. Acad. Sci. U. S. A. 92, 8841-8845
15. Duan, Z., Gao, B., Xu, W. and Xiong, S. (2008) Identification of TRIM22 as a RING finger E3 ubiquitin ligase. Biochem. Biophys. Res. Commun. 374, 502-506
16. Eldin, P., Papon, L., Oteiza, A., Brocchi, E., Lawson, T.G. and Mechti, N. (2009) TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus. J. Gen. Virol. 90, 536-545
17. Erickson, A.K., Gale, M., Jr (2008) Regulation of interferon production and innate antiviral immunity through translational control of IRF-7. Cell Res. 18, 433-435
18. Flenghi, L., Fagioli, M., Tomassoni, L., Pileri, S., Gambacorta, M., Pacini, R., Grignani, F., Casini, T., Ferrucci, P.F., Martelli, M.F., Pelicci, P.-G. and Falini, B. (1995). Characterization of a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product: immunocytochemical evidence for high expression of PML proteins on activated macrophages, endothelial cells, and epithelia. Blood 85, 1871-1880
19. Gao, B., Duan, Z., Xu, W. and Xiong, S. (2009) Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain. Hepatology 50, 424-433
20. Gongora, C., Tissot, C., Cerdan, C, and Mechti, N. (2000) The interferon-inducible Staf50 gene is downregulated during T cell costimulation by CD2 and CD28. J. Interferon Cytokine Res. 20, 955-961
21. Holcik, M. and Sonenberg, N. (2005) Translational control in stress and apoptosis. Nat. Rev. Mol. Cell. Biol. 6, 318-327
22. Horn, E.J., Albor, A., Liu, Y., El-Hizawi, S., Vanderbeek, G.E., Babcock, M., Bowden, G.T., Hennings, H., Lozano, G., Weinberg, W.C. and Kulesz-Martin, M. (2004) RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties. Carcinogenesis 25, 157-167
23. Hsieh, A.C. and Ruggero, D. (2010) Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer. Clin. Cancer Res. 16, 4914-4920
24. Joazeiro, C.A. and Weissman, A.M. (2000) RING finger proteins: mediators of ubiquitin ligase activity. Cell 102, 549-552
25. Kajaste-Rudnitski, A., Marelli, S.S., Pultrone, C., Pertel, T., Uchil, P.D., Mechti, N., Mothes, W., Poli, G., Luban, J. and Vicenzi, E. (2011) TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements. J. Virol. 85, 5183-5196
26. Kentsis, A., Dwyer, E.C., Perez, J.M., Sharma, M., Chen, A., Pan, Z.Q. and Borden, K.L. (2001) The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E. J. Mol. Biol. 312, 609-623
27. Lai, H.K. and Borden, K.L. (2000) The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA. Oncogene 19, 1623-1634
28. Livingstone, M., Atas, E., Meller, A. and Sonenberg, N. (2010) Mechanisms governing the control of mRNA translation. Phys. Biol. 7, 021001
29. Meroni, G. and Diez-Roux, G. (2005) TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. Bioessays 27, 1147-1157
30. Moerke, N.J., Aktas, H., Chen, H., Cantel, S., Reibarkh, M.Y., Fahmy, A., Gross, J.D., Degterev, A., Yuan, J., Chorev, M., Halperin, J.A. and Wagner, G. (2007) Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell 128, 257-267
31. Obad, S., Brunnstrom, H., Vallon-Christersson, J., Borg, A., Drott, K. and Gullberg, U. (2004) Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells. Oncogene 23, 4050-4059.
32. Obad, S., Olofsson, T., Mechti, N., Gullberg, U. and Drott, K. (2007) Regulation of the interferon-inducible p53 target gene TRIM22 (Staf50) in human T lymphocyte activation. J. Interferon Cytokine Res. 27, 857-864
33. Petersson, J., Lonnbro, P., Herr, A.M., Morgelin, M., Gullberg, U. and Drott, K. (2010) The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase. Exp. Cell Res. 316, 568-579
34. Richter, J.D. and Sonenberg, N. (2005) Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433, 477-480
35. Salomoni, P., Ferguson, B.J., Wyllie, A.H. and Rich, T. (2008) New insights into the role of PML in tumour suppression. Cell Res. 18, 622-640
36. Sardiello, M., Cairo, S., Fontanella, B., Ballabio, A. and Meroni, G. (2008) Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties. BMC Evol. Biol. 8, 225
37. Silvera, D., Formenti, S.C. and Schneider, R.J. (2010) Translational control in cancer. Nat. Rev. Cancer 10, 254-266
38. Singh, R., Gaiha, G., Werner, L., McKim, K., Mlisana, K., Luban, J., Walker, B.D., Karim, S.S., Brass, A.L. and Ndung'u, T. (2011) Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. J. Virol. 85, 208-216
39. Smith, R.W., Graham, S.V. and Gray, N.K. (2008) Regulation of translation initiation by herpesviruses. Biochem. Soc. Trans. 36, 701-707
40. Sonenberg, N. (2008) eIF4E, the mRNA cap-binding protein: from basic discovery to translational research. Biochem. Cell Biol. 86, 178-183
41. Sonenberg, N. and Gingras, A.C. (1998) The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr. Opin. Cell Biol. 10, 268-275
42. Sukarieh, R., Sonenberg, N. and Pelletier, J. (2010) Nuclear assortment of eIF4E coincides with shut-off of host protein synthesis upon poliovirus infection. J. Gen. Virol. 91, 1224-1228
43. Tissot, C. and Mechti, N. (1995) Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression. J. Biol. Chem. 270, 14891-14898
44. Topisirovic, I., Svitkin, Y.V., Sonenberg, N. and Shatkin, A.J. (2011) Cap and cap-binding proteins in the control of gene expression. Wiley Interdiscip. Rev. RNA 2, 277-298
45. Urano, T., Saito, T., Tsukui, T., Fujita, M., Hosoi, T., Muramatsu, M., Ouchi, Y. and Inoue, S. (2002) Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature 417, 871-875
46. Van Der Kelen, K., Beyaert, R., Inze, D. and De Veylder, L. (2009) Translational control of eukaryotic gene expression. Crit. Rev. Biochem. Mol. Biol. 44, 143-168
47. von der Haar, T., Gross, J.D., Wagner, G. and McCarthy, J.E. (2004) The mRNA cap-binding protein eIF4E in post-transcriptional gene expression. Nat. Struct. Mol. Biol. 11, 503-511
48. Zhao, Y., Xu, D., Jiang, Y. and Zhang, L. (2010) Dual functions of interferon regulatory factors 7C in Epstein-Barr virus-mediated transformation of human B lymphocytes. PLoS One 5, e9459