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Volumn 88, Issue 7, 2010, Pages 645-652

Regulation of tumor suppressor p53 at the RNA level

Author keywords

AU rich elements; miRNA; mRNA regulation; p53; Wig 1

Indexed keywords

ANTAGOMIR; ANTIGEN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HUMAN ANTIGEN R; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MICRORNA; PROTEIN; PROTEIN BAX; PROTEIN MDM2; PROTEIN NOXA; PROTEIN P53; PUMA PROTEIN; QUERCETIN; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WIG 1 PROTEIN; 3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION;

EID: 77954537044     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-010-0609-2     Document Type: Review
Times cited : (63)

References (97)
  • 1
    • 69149089025 scopus 로고    scopus 로고
    • 30 years and a long way into p53 research
    • 10.1016/S1470-2045(09)70198-6 19717093
    • P Hainaut KG Wiman 2009 30 years and a long way into p53 research Lancet Oncol 10 913 919 10.1016/S1470-2045(09)70198-6 19717093
    • (2009) Lancet Oncol , vol.10 , pp. 913-919
    • Hainaut, P.1    Wiman, K.G.2
  • 4
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • 10.1038/35042675 1:CAS:528:DC%2BD3cXosVemtrY%3D 11099028
    • B Vogelstein D Lane AJ Levine 2000 Surfing the p53 network Nature 408 307 310 10.1038/35042675 1:CAS:528:DC%2BD3cXosVemtrY%3D 11099028
    • (2000) Nature , vol.408 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 5
    • 70349459599 scopus 로고    scopus 로고
    • P53 and metabolism
    • 10.1038/nrc2715 1:CAS:528:DC%2BD1MXhtFentb%2FM
    • KH Vousden KM Ryan 2009 p53 and metabolism Nat Rev, Cancer 9 691 700 10.1038/nrc2715 1:CAS:528:DC%2BD1MXhtFentb%2FM
    • (2009) Nat Rev, Cancer , vol.9 , pp. 691-700
    • Vousden, K.H.1    Ryan, K.M.2
  • 6
    • 69349098834 scopus 로고    scopus 로고
    • Stem cells: The promises and perils of p53
    • 10.1038/4601085a 10.1038/4601085a 1:CAS:528:DC%2BD1MXhtVGiurjK 19713919
    • V Krizhanovsky SW Lowe 2009 Stem cells: the promises and perils of p53 Nature 460 1085 1086 10.1038/4601085a 10.1038/4601085a 1:CAS:528: DC%2BD1MXhtVGiurjK 19713919
    • (2009) Nature , vol.460 , pp. 1085-1086
    • Krizhanovsky, V.1    Lowe, S.W.2
  • 7
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • DOI 10.1038/nrc864
    • KH Vousden X Lu 2002 Live or let die: the cell's response to p53 Nat Rev, Cancer 2 594 604 10.1038/nrc864 10.1038/nrc864 1:CAS:528:DC%2BD38XlslGqsL8%3D (Pubitemid 37328926)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.8 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 8
    • 0033993563 scopus 로고    scopus 로고
    • The ARF/p53 pathway
    • DOI 10.1016/S0959-437X(99)00038-6
    • CJ Sherr JD Weber 2000 The ARF/p53 pathway Curr Opin Genet Dev 10 94 99 10.1016/S0959-437X(99)00038-6 1:CAS:528:DC%2BD3cXhslOks70%3D 10679383 S0959-437X(99)00038-6 [pii] (Pubitemid 30113711)
    • (2000) Current Opinion in Genetics and Development , vol.10 , Issue.1 , pp. 94-99
    • Sherr, C.J.1    Weber, J.D.2
  • 9
    • 0037349289 scopus 로고    scopus 로고
    • p53 has a direct apoptogenic role at the mitochondria
    • DOI 10.1016/S1097-2765(03)00050-9
    • M Mihara S Erster A Zaika O Petrenko T Chittenden P Pancoska UM Moll 2003 p53 has a direct apoptogenic role at the mitochondria Mol Cell 11 577 590 10.1016/S1097-2765(03)00050-9 1:CAS:528:DC%2BD3sXjtVWktrk%3D 12667443 S1097276503000509 [pii] (Pubitemid 36385115)
    • (2003) Molecular Cell , vol.11 , Issue.3 , pp. 577-590
    • Mihara, M.1    Erster, S.2    Zaika, A.3    Petrenko, O.4    Chittenden, T.5    Pancoska, P.6    Moll, U.M.7
  • 10
    • 37249038565 scopus 로고    scopus 로고
    • p53 family isoforms
    • DOI 10.2174/138920107783018444
    • JC Bourdon 2007 p53 Family isoforms Curr Pharm Biotechnol 8 332 336 10.2174/138920107783018444 1:CAS:528:DC%2BD1cXitVSms70%3D 18289041 (Pubitemid 350268191)
    • (2007) Current Pharmaceutical Biotechnology , vol.8 , Issue.6 , pp. 332-336
    • Bourdon, J.-C.1
  • 11
    • 35148826938 scopus 로고    scopus 로고
    • Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm
    • DOI 10.1016/j.ccr.2007.10.001, PII S153561080700270X
    • T Soussi KG Wiman 2007 Shaping genetic alterations in human cancer: the p53 mutation paradigm Cancer Cell 12 303 312 10.1016/j.ccr.2007.10.001 1:CAS:528:DC%2BD2sXht1ais7zN 17936556 (Pubitemid 47539312)
    • (2007) Cancer Cell , vol.12 , Issue.4 , pp. 303-312
    • Soussi, T.1    Wiman, K.G.2
  • 12
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • 10.1038/nrc2693 1:CAS:528:DC%2BD1MXhtVWhsb7J
    • R Brosh V Rotter 2009 When mutants gain new powers: news from the mutant p53 field Nat Rev, Cancer 9 701 713 10.1038/nrc2693 1:CAS:528:DC%2BD1MXhtVWhsb7J
    • (2009) Nat Rev, Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 14
    • 33646799132 scopus 로고    scopus 로고
    • Strategies for therapeutic targeting of the p53 pathway in cancer
    • 10.1038/sj.cdd.4401921 1:CAS:528:DC%2BD28Xks1OrtbY%3D 16557267
    • KG Wiman 2006 Strategies for therapeutic targeting of the p53 pathway in cancer Cell Death Differ 13 921 926 10.1038/sj.cdd.4401921 1:CAS:528: DC%2BD28Xks1OrtbY%3D 16557267
    • (2006) Cell Death Differ , vol.13 , pp. 921-926
    • Wiman, K.G.1
  • 15
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • DOI 10.1038/nature05529, PII NATURE05529
    • W Xue L Zender C Miething RA Dickins E Hernando V Krizhanovsky C Cordon-Cardo SW Lowe 2007 Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas Nature 445 656 660 10.1038/nature05529 1:CAS:528:DC%2BD2sXhtlOrtbo%3D 17251933 (Pubitemid 46232886)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 19
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis
    • DOI 10.1016/j.molcel.2007.05.017, PII S1097276507003188
    • N Raver-Shapira E Marciano E Meiri Y Spector N Rosenfeld N Moskovits Z Bentwich M Oren 2007 Transcriptional activation of miR-34a contributes to p53-mediated apoptosis Mol Cell 26 731 743 10.1016/j.molcel.2007.05.017 1:CAS:528:DC%2BD2sXnt1Cqur0%3D 17540598 (Pubitemid 46856247)
    • (2007) Molecular Cell , vol.26 , Issue.5 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3    Spector, Y.4    Rosenfeld, N.5    Moskovits, N.6    Bentwich, Z.7    Oren, M.8
  • 20
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
    • 1:CAS:528:DC%2BD2sXhtFWlsr3O 17554199
    • V Tarasov P Jung B Verdoodt D Lodygin A Epanchintsev A Menssen G Meister H Hermeking 2007 Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest Cell Cycle 6 1586 1593 1:CAS:528:DC%2BD2sXhtFWlsr3O 17554199
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 22
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • DOI 10.1158/0008-5472.CAN-07-1585
    • DC Corney A Flesken-Nikitin AK Godwin W Wang AY Nikitin 2007 MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth Cancer Res 67 8433 8438 10.1158/0008-5472.CAN-07-1585 1:CAS:528:DC%2BD2sXhtVCit7%2FF 17823410 (Pubitemid 47437414)
    • (2007) Cancer Research , vol.67 , Issue.18 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Yu.5
  • 23
    • 12444252198 scopus 로고    scopus 로고
    • Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
    • DOI 10.1038/sj.onc.1206477
    • A Mirza Q Wu L Wang T McClanahan WR Bishop F Gheyas W Ding B Hutchins T Hockenberry P Kirschmeier JR Greene S Liu 2003 Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression Oncogene 22 3645 3654 10.1038/sj.onc.1206477 10.1038/sj.onc.1206477 1:CAS:528:DC%2BD3sXktlSjtrs%3D 12789273 (Pubitemid 36765324)
    • (2003) Oncogene , vol.22 , Issue.23 , pp. 3645-3654
    • Mirza, A.1    Wu, Q.2    Wang, L.3    McClanahan, T.4    Bishop, W.R.5    Gheyas, F.6    Ding, W.7    Hutchins, B.8    Hockenberry, T.9    Kirschmeier, P.10    Greene, J.R.11    Liu, S.12
  • 24
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • 10.1038/emboj.2009.214 1:CAS:528:DC%2BD1MXpvFCktbg%3D 19696742
    • HL Yan G Xue Q Mei YZ Wang FX Ding MF Liu MH Lu Y Tang HY Yu SH Sun 2009 Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis EMBO J 28 2719 2732 10.1038/emboj.2009.214 1:CAS:528:DC%2BD1MXpvFCktbg%3D 19696742
    • (2009) EMBO J , vol.28 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3    Wang, Y.Z.4    Ding, F.X.5    Liu, M.F.6    Lu, M.H.7    Tang, Y.8    Yu, H.Y.9    Sun, S.H.10
  • 26
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • 10.1038/nature08199 1:CAS:528:DC%2BD1MXovFymtL0%3D 19626115
    • HI Suzuki K Yamagata K Sugimoto T Iwamoto S Kato K Miyazono 2009 Modulation of microRNA processing by p53 Nature 460 529 533 10.1038/nature08199 1:CAS:528:DC%2BD1MXovFymtL0%3D 19626115
    • (2009) Nature , vol.460 , pp. 529-533
    • Suzuki, H.I.1    Yamagata, K.2    Sugimoto, K.3    Iwamoto, T.4    Kato, S.5    Miyazono, K.6
  • 27
    • 0029115918 scopus 로고
    • Negative feedback regulation of wild-type p53 biosynthesis
    • 1:CAS:528:DyaK2MXovVektrw%3D 7556087
    • J Mosner T Mummenbrauer C Bauer G Sczakiel F Grosse W Deppert 1995 Negative feedback regulation of wild-type p53 biosynthesis EMBO J 14 4442 4449 1:CAS:528:DyaK2MXovVektrw%3D 7556087
    • (1995) EMBO J , vol.14 , pp. 4442-4449
    • Mosner, J.1    Mummenbrauer, T.2    Bauer, C.3    Sczakiel, G.4    Grosse, F.5    Deppert, W.6
  • 28
    • 0033756586 scopus 로고    scopus 로고
    • P53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4
    • 10.1128/MCB.20.22.8420-8431.2000 1:CAS:528:DC%2BD3cXotFWrt7c%3D 11046139
    • SJ Miller T Suthiphongchai GP Zambetti ME Ewen 2000 p53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4 Mol Cell Biol 20 8420 8431 10.1128/MCB.20.22.8420-8431.2000 1:CAS:528:DC%2BD3cXotFWrt7c%3D 11046139
    • (2000) Mol Cell Biol , vol.20 , pp. 8420-8431
    • Miller, S.J.1    Suthiphongchai, T.2    Zambetti, G.P.3    Ewen, M.E.4
  • 30
    • 0035797499 scopus 로고    scopus 로고
    • p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA
    • DOI 10.1038/sj.onc.1204630
    • B Galy L Creancier L Prado-Lourenco AC Prats H Prats 2001 p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA Oncogene 20 4613 4620 10.1038/sj.onc.1204630 1:CAS:528:DC%2BD3MXmtFejs7Y%3D 11498784 (Pubitemid 32762433)
    • (2001) Oncogene , vol.20 , Issue.34 , pp. 4613-4620
    • Galy, B.1    Creancier, L.2    Prado-Lourenco, L.3    Prats, A.-C.4    Prats, H.5
  • 31
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • 10.1016/j.cell.2009.04.037 10.1016/j.cell.2009.04.037 1:CAS:528:DC%2BD1MXlvFams74%3D 19410540
    • KH Vousden C Prives 2009 Blinded by the light: the growing complexity of p53 Cell 137 413 431 10.1016/j.cell.2009.04.037 10.1016/j.cell.2009.04.037 1:CAS:528:DC%2BD1MXlvFams74%3D 19410540
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 32
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • 1:CAS:528:DyaK38XhvFSltg%3D%3D 1933891
    • MB Kastan O Onyekwere D Sidransky B Vogelstein RW Craig 1991 Participation of p53 protein in the cellular response to DNA damage Cancer Res 51 6304 6311 1:CAS:528:DyaK38XhvFSltg%3D%3D 1933891
    • (1991) Cancer Res , vol.51 , pp. 6304-6311
    • Kastan, M.B.1    Onyekwere, O.2    Sidransky, D.3    Vogelstein, B.4    Craig, R.W.5
  • 33
    • 26244459242 scopus 로고    scopus 로고
    • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
    • DOI 10.1016/j.cell.2005.07.034, PII S0092867405008147
    • M Takagi MJ Absalon KG McLure MB Kastan 2005 Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin Cell 123 49 63 10.1016/j.cell.2005.07.034 1:CAS:528:DC%2BD2MXhtFelt7nF 16213212 (Pubitemid 41414528)
    • (2005) Cell , vol.123 , Issue.1 , pp. 49-63
    • Takagi, M.1    Absalon, M.J.2    McLure, K.G.3    Kastan, M.B.4
  • 34
    • 33746855405 scopus 로고    scopus 로고
    • The identification of an internal ribosomal entry site in the 5′-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage
    • DOI 10.1038/sj.onc.1209483, PII 1209483
    • DQ Yang MJ Halaby Y Zhang 2006 The identification of an internal ribosomal entry site in the 5′-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage Oncogene 25 4613 4619 10.1038/sj.onc.1209483 1:CAS:528:DC%2BD28Xnsl2jsb8%3D 16607284 (Pubitemid 44175120)
    • (2006) Oncogene , vol.25 , Issue.33 , pp. 4613-4619
    • Yang, D.-Q.1    Halaby, M.-J.2    Zhang, Y.3
  • 35
    • 37549051733 scopus 로고    scopus 로고
    • Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage
    • 10.1128/MCB.01126-07 1:CAS:528:DC%2BD1cXmt1eqtw%3D%3D 17938203
    • H Liu ZG Lu Y Miki K Yoshida 2007 Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage Mol Cell Biol 27 8480 8491 10.1128/MCB.01126-07 1:CAS:528:DC%2BD1cXmt1eqtw%3D%3D 17938203
    • (2007) Mol Cell Biol , vol.27 , pp. 8480-8491
    • Liu, H.1    Lu, Z.G.2    Miki, Y.3    Yoshida, K.4
  • 36
    • 0034702232 scopus 로고    scopus 로고
    • Compromised HOXA5 function can limit p53 expression in human breast tumours
    • DOI 10.1038/35016125
    • V Raman SA Martensen D Reisman E Evron WF Odenwald E Jaffee J Marks S Sukumar 2000 Compromised HOXA5 function can limit p53 expression in human breast tumours Nature 405 974 978 10.1038/35016125 1:CAS:528:DC%2BD3cXks1WktLg%3D 10879542 (Pubitemid 30435057)
    • (2000) Nature , vol.405 , Issue.6789 , pp. 974-978
    • Raman, V.1    Martenser, S.A.2    Reisman, D.3    Evron, E.4    Odenwald, W.F.5    Jaffee, E.6    Marks, J.7    Sukumar, S.8
  • 37
    • 10344247666 scopus 로고    scopus 로고
    • The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
    • DOI 10.1038/nature03147
    • RT Phan R Dalla-Favera 2004 The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells Nature 432 635 639 10.1038/nature03147 10.1038/nature03147 1:CAS:528:DC%2BD2cXhtVeht7rE 15577913 (Pubitemid 39626271)
    • (2004) Nature , vol.432 , Issue.7017 , pp. 635-639
    • Phan, R.T.1    Dalla-Favera, R.2
  • 38
    • 33745020716 scopus 로고    scopus 로고
    • Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: A basis for p53 haplo-insufficiency
    • DOI 10.1038/sj.onc.1209387, PII 1209387
    • CJ Lynch J Milner 2006 Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency Oncogene 25 3463 3470 10.1038/sj.onc.1209387 1:CAS:528:DC%2BD28XlsVersbs%3D 16449974 (Pubitemid 43877049)
    • (2006) Oncogene , vol.25 , Issue.24 , pp. 3463-3470
    • Lynch, C.J.1    Milner, J.2
  • 39
    • 68149157545 scopus 로고    scopus 로고
    • P53 and little brother p53/47: Linking IRES activities with protein functions
    • 10.1038/onc.2009.138 1:CAS:528:DC%2BD1MXms1aksr8%3D 19483723
    • R Grover MM Candeias R Fahraeus S Das 2009 p53 and little brother p53/47: linking IRES activities with protein functions Oncogene 28 2766 2772 10.1038/onc.2009.138 1:CAS:528:DC%2BD1MXms1aksr8%3D 19483723
    • (2009) Oncogene , vol.28 , pp. 2766-2772
    • Grover, R.1    Candeias, M.M.2    Fahraeus, R.3    Das, S.4
  • 40
    • 53949121380 scopus 로고    scopus 로고
    • Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26
    • 10.1016/j.molcel.2008.08.031 1:CAS:528:DC%2BD1cXhtlehsb3K 18951086
    • Y Ofir-Rosenfeld K Boggs D Michael MB Kastan M Oren 2008 Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26 Mol Cell 32 180 189 10.1016/j.molcel.2008.08.031 1:CAS:528:DC%2BD1cXhtlehsb3K 18951086
    • (2008) Mol Cell , vol.32 , pp. 180-189
    • Ofir-Rosenfeld, Y.1    Boggs, K.2    Michael, D.3    Kastan, M.B.4    Oren, M.5
  • 41
    • 0035939819 scopus 로고    scopus 로고
    • The rapid destabilization of p53 mRNA in immortal chicken embryo fibroblast cells
    • DOI 10.1038/sj.onc.1204664
    • H Kim S You LK Foster J Farris DN Foster 2001 The rapid destabilization of p53 mRNA in immortal chicken embryo fibroblast cells Oncogene 20 5118 5123 10.1038/sj.onc.1204664 1:CAS:528:DC%2BD3MXmslGmu74%3D 11526500 (Pubitemid 32844040)
    • (2001) Oncogene , vol.20 , Issue.37 , pp. 5118-5123
    • Kim, H.1    You, S.2    Foster, L.K.3    Farris, J.4    Foster, D.N.5
  • 42
    • 60549107869 scopus 로고    scopus 로고
    • Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage
    • 10.1016/j.molcel.2009.01.028 1:CAS:528:DC%2BD1MXltFSnu70%3D 19250907
    • S Mahmoudi S Henriksson M Corcoran C Mendez-Vidal KG Wiman M Farnebo 2009 Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage Mol Cell 33 462 471 10.1016/j.molcel.2009.01.028 1:CAS:528: DC%2BD1MXltFSnu70%3D 19250907
    • (2009) Mol Cell , vol.33 , pp. 462-471
    • Mahmoudi, S.1    Henriksson, S.2    Corcoran, M.3    Mendez-Vidal, C.4    Wiman, K.G.5    Farnebo, M.6
  • 44
    • 58849093262 scopus 로고    scopus 로고
    • Revisiting the principles of microRNA target recognition and mode of action
    • 10.1038/nrm2619 1:CAS:528:DC%2BD1MXltFWqtg%3D%3D
    • P Brodersen O Voinnet 2009 Revisiting the principles of microRNA target recognition and mode of action Nat Rev 10 141 148 10.1038/nrm2619 1:CAS:528:DC%2BD1MXltFWqtg%3D%3D
    • (2009) Nat Rev , vol.10 , pp. 141-148
    • Brodersen, P.1    Voinnet, O.2
  • 45
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • 10.1038/nrg2504 1:CAS:528:DC%2BD1MXlvFChtA%3D%3D
    • M Ghildiyal PD Zamore 2009 Small silencing RNAs: an expanding universe Nat Rev, Genet 10 94 108 10.1038/nrg2504 1:CAS:528:DC%2BD1MXlvFChtA%3D%3D
    • (2009) Nat Rev, Genet , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 46
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • 10.1101/gad.1767609 1:CAS:528:DC%2BD1MXks1Sruro%3D 19293287
    • MT Le C Teh N Shyh-Chang H Xie B Zhou V Korzh HF Lodish B Lim 2009 MicroRNA-125b is a novel negative regulator of p53 Genes Dev 23 862 876 10.1101/gad.1767609 1:CAS:528:DC%2BD1MXks1Sruro%3D 19293287
    • (2009) Genes Dev , vol.23 , pp. 862-876
    • Le, M.T.1    Teh, C.2    Shyh-Chang, N.3    Xie, H.4    Zhou, B.5    Korzh, V.6    Lodish, H.F.7    Lim, B.8
  • 47
    • 72049115805 scopus 로고    scopus 로고
    • MicroRNA 125a and its regulation of the p53 tumor suppressor gene
    • 10.1016/j.febslet.2009.10.002 1:CAS:528:DC%2BD1MXhsVWls7vN 19818772
    • Y Zhang JS Gao X Tang LD Tucker P Quesenberry I Rigoutsos B Ramratnam 2009 MicroRNA 125a and its regulation of the p53 tumor suppressor gene FEBS Lett 583 3725 3730 10.1016/j.febslet.2009.10.002 1:CAS:528:DC%2BD1MXhsVWls7vN 19818772
    • (2009) FEBS Lett , vol.583 , pp. 3725-3730
    • Zhang, Y.1    Gao, J.S.2    Tang, X.3    Tucker, L.D.4    Quesenberry, P.5    Rigoutsos, I.6    Ramratnam, B.7
  • 48
    • 13544267521 scopus 로고    scopus 로고
    • Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis
    • DOI 10.1016/j.cell.2004.12.009
    • B Schumacher M Hanazawa MH Lee S Nayak K Volkmann ER Hofmann M Hengartner T Schedl A Gartner 2005 Translational repression of Caenorhabditis elegans p53 by GLD-1 regulates DNA damage-induced apoptosis Cell 120 357 368 10.1016/j.cell.2004.12.009 1:CAS:528:DC%2BD2MXhs1Krt78%3D 15707894 (Pubitemid 40222430)
    • (2005) Cell , vol.120 , Issue.3 , pp. 357-368
    • Schumacher, B.1    Hanazawa, M.2    Lee, M.-H.3    Nayak, S.4    Volkmann, K.5    Hofmann, R.6    Hengartner, M.7    Schedl, T.8    Gartner, A.9
  • 49
    • 70350707749 scopus 로고    scopus 로고
    • Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets
    • 10.1101/gr.091181.109 1:CAS:528:DC%2BD1MXhsVSmtLnI 19767416
    • J Hausser M Landthaler L Jaskiewicz D Gaidatzis M Zavolan 2009 Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets Genome Res 19 2009 2020 10.1101/gr.091181.109 1:CAS:528:DC%2BD1MXhsVSmtLnI 19767416
    • (2009) Genome Res , vol.19 , pp. 2009-2020
    • Hausser, J.1    Landthaler, M.2    Jaskiewicz, L.3    Gaidatzis, D.4    Zavolan, M.5
  • 50
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • A Grimson KK Farh WK Johnston P Garrett-Engele LP Lim DP Bartel 2007 MicroRNA targeting specificity in mammals: determinants beyond seed pairing Mol Cell 27 91 105 10.1016/j.molcel.2007.06.017 10.1016/j.molcel.2007.06.017 1:CAS:528:DC%2BD2sXot1els7Y%3D 17612493 (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 51
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: Are there unifying principles?
    • DOI 10.1093/nar/gki1012
    • C Barreau L Paillard HB Osborne 2005 AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res 33 7138 7150 10.1093/nar/gki1012 10.1093/nar/gki1012 1:CAS:528:DC%2BD28XisFKqsA%3D%3D 16391004 (Pubitemid 43125082)
    • (2005) Nucleic Acids Research , vol.33 , Issue.22 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 52
    • 16844362149 scopus 로고    scopus 로고
    • Post-transcriptional regulation in cancer
    • 10.1016/j.biolcel.2004.05.002 10.1016/j.biolcel.2004.05.002 1:CAS:528:DC%2BD2cXnslGjuro%3D 15380615
    • Y Audic RS Hartley 2004 Post-transcriptional regulation in cancer Biol Cell 96 479 498 10.1016/j.biolcel.2004.05.002 10.1016/j.biolcel.2004.05.002 1:CAS:528:DC%2BD2cXnslGjuro%3D 15380615
    • (2004) Biol Cell , vol.96 , pp. 479-498
    • Audic, Y.1    Hartley, R.S.2
  • 55
    • 0033547302 scopus 로고    scopus 로고
    • A translation repressor element resides in the 3′ untranslated region of human p53 mRNA
    • 10.1038/sj.onc.1203064 1:CAS:528:DyaK1MXnvFyhsro%3D 10597243
    • L Fu W Ma S Benchimol 1999 A translation repressor element resides in the 3′ untranslated region of human p53 mRNA Oncogene 18 6419 6424 10.1038/sj.onc.1203064 1:CAS:528:DyaK1MXnvFyhsro%3D 10597243
    • (1999) Oncogene , vol.18 , pp. 6419-6424
    • Fu, L.1    Ma, W.2    Benchimol, S.3
  • 56
    • 33745849149 scopus 로고    scopus 로고
    • Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs
    • DOI 10.1074/jbc.M602344200
    • T Zou K Mazan-Mamczarz JN Rao L Liu BS Marasa AH Zhang L Xiao R Pullmann M Gorospe JY Wang 2006 Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs J Biol Chem 281 19387 19394 10.1074/jbc.M602344200 10.1074/jbc.M602344200 1:CAS:528:DC%2BD28Xms1Gqs78%3D 16690610 (Pubitemid 44035444)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.28 , pp. 19387-19394
    • Zou, T.1    Mazan-Mamczarz, K.2    Rao, J.N.3    Liu, L.4    Marasa, B.S.5    Zhang, A.-H.6    Xiao, L.7    Pullmann, R.8    Gorospe, M.9    Wang, J.-Y.10
  • 57
    • 59849105830 scopus 로고    scopus 로고
    • Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR
    • 10.1002/mc.20460 1:CAS:528:DC%2BD1MXitlClsL4%3D 18680106
    • X Tong JC Pelling 2009 Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR Mol Carcinog 48 118 129 10.1002/mc.20460 1:CAS:528:DC%2BD1MXitlClsL4%3D 18680106
    • (2009) Mol Carcinog , vol.48 , pp. 118-129
    • Tong, X.1    Pelling, J.C.2
  • 59
    • 0030693589 scopus 로고    scopus 로고
    • Wig-1, a new p53-induced gene encoding a zinc finger protein
    • 10.1038/sj.onc.1201454 10.1038/sj.onc.1201454 1:CAS:528: DyaK2sXotVWnsLs%3D 9400996
    • S Varmeh-Ziaie I Okan Y Wang KP Magnusson P Warthoe M Strauss KG Wiman 1997 Wig-1, a new p53-induced gene encoding a zinc finger protein Oncogene 15 2699 2704 10.1038/sj.onc.1201454 10.1038/sj.onc.1201454 1:CAS:528: DyaK2sXotVWnsLs%3D 9400996
    • (1997) Oncogene , vol.15 , pp. 2699-2704
    • Varmeh-Ziaie, S.1    Okan, I.2    Wang, Y.3    Magnusson, K.P.4    Warthoe, P.5    Strauss, M.6    Wiman, K.G.7
  • 60
    • 0035817786 scopus 로고    scopus 로고
    • Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein
    • DOI 10.1038/sj.onc.1204722
    • F Hellborg W Qian C Mendez-Vidal C Asker M Kost-Alimova M Wilhelm S Imreh KG Wiman 2001 Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein Oncogene 20 5466 5474 10.1038/sj.onc.1204722 10.1038/sj.onc.1204722 1:CAS:528:DC%2BD3MXntFWjsb8%3D 11571644 (Pubitemid 32889483)
    • (2001) Oncogene , vol.20 , Issue.39 , pp. 5466-5474
    • Hellborg, F.1    Qian, W.2    Mendez-Vidal, C.3    Asker, C.4    Kost-Alimova, M.5    Wilhelm, M.6    Imreh, S.7    Wiman, K.G.8
  • 61
    • 0030802364 scopus 로고    scopus 로고
    • A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
    • DOI 10.1093/emboj/16.14.4384
    • D Israeli E Tessler Y Haupt A Elkeles S Wilder R Amson A Telerman M Oren 1997 A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis EMBO J 16 4384 4392 10.1093/emboj/16.14. 4384 10.1093/emboj/16.14.4384 1:CAS:528:DyaK2sXkvFeqtbg%3D 9250682 (Pubitemid 27298191)
    • (1997) EMBO Journal , vol.16 , Issue.14 , pp. 4384-4392
    • Israeli, D.1    Tessler, E.2    Haupt, Y.3    Elkeles, A.4    Wilder, S.5    Amson, R.6    Telerman, A.7    Oren, M.8
  • 62
    • 0036566780 scopus 로고    scopus 로고
    • The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity
    • 10.1093/nar/30.9.1991 1:CAS:528:DC%2BD38XktFGhtbY%3D 11972337
    • C Mendez-Vidal MT Wilhelm F Hellborg W Qian KG Wiman 2002 The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity Nucleic Acids Res 30 1991 1996 10.1093/nar/30.9.1991 1:CAS:528: DC%2BD38XktFGhtbY%3D 11972337
    • (2002) Nucleic Acids Res , vol.30 , pp. 1991-1996
    • Mendez-Vidal, C.1    Wilhelm, M.T.2    Hellborg, F.3    Qian, W.4    Wiman, K.G.5
  • 63
    • 16544389806 scopus 로고    scopus 로고
    • The p53-induced Wig-1 zinc finger protein is highly conserved from fish to man
    • 1:CAS:528:DC%2BD2cXkvFaisLg%3D 15138600
    • F Hellborg KG Wiman 2004 The p53-induced Wig-1 zinc finger protein is highly conserved from fish to man Int J Oncol 24 1559 1564 1:CAS:528: DC%2BD2cXkvFaisLg%3D 15138600
    • (2004) Int J Oncol , vol.24 , pp. 1559-1564
    • Hellborg, F.1    Wiman, K.G.2
  • 64
    • 33746369766 scopus 로고    scopus 로고
    • The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs
    • DOI 10.1016/j.febslet.2006.07.005, PII S0014579306008386
    • C Mendez Vidal M Prahl KG Wiman 2006 The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs FEBS Lett 580 4401 4408 10.1016/j.febslet.2006.07.005 10.1016/j.febslet.2006.07.005 1:CAS:528:DC%2BD28Xns12lsLg%3D 16844115 (Pubitemid 44118258)
    • (2006) FEBS Letters , vol.580 , Issue.18 , pp. 4401-4408
    • Mendez Vidal, C.1    Prahl, M.2    Wiman, K.G.3
  • 65
    • 0030967951 scopus 로고    scopus 로고
    • RNA helicase A mediates association of CBP with RNA polymerase II
    • DOI 10.1016/S0092-8674(00)80376-1
    • T Nakajima C Uchida SF Anderson CG Lee J Hurwitz JD Parvin M Montminy 1997 RNA helicase A mediates association of CBP with RNA polymerase II Cell 90 1107 1112 10.1016/S0092-8674(00)80376-1 1:CAS:528:DyaK2sXmtlOmurY%3D 9323138 (Pubitemid 27408524)
    • (1997) Cell , vol.90 , Issue.6 , pp. 1107-1112
    • Nakajima, T.1    Uchida, C.2    Anderson, S.F.3    Chee-Gun, L.4    Hurwitz, J.5    Parvin, J.D.6    Montminy, M.7
  • 66
    • 0031830844 scopus 로고    scopus 로고
    • BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A
    • DOI 10.1038/930
    • SF Anderson BP Schlegel T Nakajima ES Wolpin JD Parvin 1998 BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A Nat Genet 19 254 256 10.1038/930 1:CAS:528:DyaK1cXls1SnsL4%3D 9662397 (Pubitemid 28309336)
    • (1998) Nature Genetics , vol.19 , Issue.3 , pp. 254-256
    • Anderson, S.F.1    Schlegel, B.P.2    Nakajima, T.3    Wolpin, E.S.4    Parvin, J.D.5
  • 67
    • 4544264117 scopus 로고    scopus 로고
    • RNA helicase A interacts with nuclear factor κB p65 and functions as a transcriptional coactivator
    • DOI 10.1111/j.1432-1033.2004.04314.x
    • T Tetsuka H Uranishi T Sanda K Asamitsu JP Yang F Wong-Staal T Okamoto 2004 RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator Eur J Biochem 271 3741 3751 10.1111/j.1432-1033. 2004.04314.x 1:CAS:528:DC%2BD2cXnvVWms7g%3D 15355351 (Pubitemid 39233616)
    • (2004) European Journal of Biochemistry , vol.271 , Issue.18 , pp. 3741-3751
    • Tetsuka, T.1    Uranishi, H.2    Sanda, T.3    Asamitsu, K.4    Yang, J.-P.5    Wong-Staal, F.6    Okamoto, T.7
  • 69
    • 33646930155 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, α (I) mRNA stability
    • DOI 10.1074/jbc.M510925200
    • M Fahling R Mrowka A Steege P Martinka PB Persson BJ Thiele 2006 Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability J Biol Chem 281 9279 9286 10.1074/jbc.M510925200 10.1074/jbc.M510925200 16464861 (Pubitemid 43864643)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.14 , pp. 9279-9286
    • Fahling, M.1    Mrowka, R.2    Steege, A.3    Martinka, P.4    Persson, P.B.5    Thiele, B.J.6
  • 70
    • 33847239085 scopus 로고    scopus 로고
    • Suppression of p53-activated gene, PAG608, attenuates methamphetamine-induced neurotoxicity
    • 10.1016/j.neulet.2006.12.036 10.1016/j.neulet.2006.12.036 1:CAS:528:DC%2BD2sXitl2js7Y%3D 17234339
    • M Asanuma I Miyazaki Y Higashi FJ Diaz-Corrales M Shimizu K Miyoshi N Ogawa 2007 Suppression of p53-activated gene, PAG608, attenuates methamphetamine-induced neurotoxicity Neurosci Lett 414 263 267 10.1016/j.neulet.2006.12.036 10.1016/j.neulet.2006.12.036 1:CAS:528: DC%2BD2sXitl2js7Y%3D 17234339
    • (2007) Neurosci Lett , vol.414 , pp. 263-267
    • Asanuma, M.1    Miyazaki, I.2    Higashi, Y.3    Diaz-Corrales, F.J.4    Shimizu, M.5    Miyoshi, K.6    Ogawa, N.7
  • 71
    • 34249715781 scopus 로고    scopus 로고
    • mRNA stability control: A clandestine force in normal and malignant hematopoiesis
    • DOI 10.1038/sj.leu.2404656, PII 2404656
    • RA Steinman 2007 mRNA stability control: a clandestine force in normal and malignant hematopoiesis Leukemia 21 1158 1171 10.1038/sj.leu.2404656 10.1038/sj.leu.2404656 1:CAS:528:DC%2BD2sXlsFOhsrg%3D 17392821 (Pubitemid 46838514)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1158-1171
    • Steinman, R.A.1
  • 72
    • 0035266295 scopus 로고    scopus 로고
    • HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3′ untranslated regions of cytokine and angiogenic factor mRNAs
    • 1:CAS:528:DC%2BD3MXit1Ogsbs%3D 11280780
    • LB Nabors GY Gillespie L Harkins PH King 2001 HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3′ untranslated regions of cytokine and angiogenic factor mRNAs Cancer Res 61 2154 2161 1:CAS:528:DC%2BD3MXit1Ogsbs%3D 11280780
    • (2001) Cancer Res , vol.61 , pp. 2154-2161
    • Nabors, L.B.1    Gillespie, G.Y.2    Harkins, L.3    King, P.H.4
  • 74
    • 33747601610 scopus 로고    scopus 로고
    • Expression of the ELAV-like protein HuR in human colon cancer: Association with tumor stage and cyclooxygenase-2
    • DOI 10.1038/modpathol.3800645, PII 3800645
    • C Denkert I Koch N von Keyserlingk A Noske S Niesporek M Dietel W Weichert 2006 Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2 Mod Pathol 19 1261 1269 10.1038/modpathol.3800645 1:CAS:528:DC%2BD28XotlCgu74%3D 16799479 (Pubitemid 44268197)
    • (2006) Modern Pathology , vol.19 , Issue.9 , pp. 1261-1269
    • Denkert, C.1    Koch, I.2    Von Keyserlingk, N.3    Noske, A.4    Niesporek, S.5    Dietel, M.6    Weichert, W.7
  • 75
    • 4143134276 scopus 로고    scopus 로고
    • Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma
    • DOI 10.1158/1078-0432.CCR-04-0070
    • C Denkert W Weichert KJ Winzer BM Muller A Noske S Niesporek G Kristiansen H Guski M Dietel S Hauptmann 2004 Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma Clin Cancer Res 10 5580 5586 10.1158/1078-0432.CCR-04-0070 1:CAS:528:DC%2BD2cXmvFSlur0%3D 15328200 (Pubitemid 39100499)
    • (2004) Clinical Cancer Research , vol.10 , Issue.16 , pp. 5580-5586
    • Denkert, C.1    Weichert, W.2    Winzer, K.-J.3    Muller, B.-M.4    Noske, A.5    Niesporek, S.6    Kristiansen, G.7    Guski, H.8    Dietel, M.9    Hauptmann, S.10
  • 76
    • 0035161588 scopus 로고    scopus 로고
    • Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements
    • 1:CAS:528:DC%2BD3MXos1Khu78%3D 11720287
    • G Stoecklin P Stoeckle M Lu O Muehlemann C Moroni 2001 Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements RNA 7 1578 1588 1:CAS:528:DC%2BD3MXos1Khu78%3D 11720287
    • (2001) RNA , vol.7 , pp. 1578-1588
    • Stoecklin, G.1    Stoeckle, P.2    Lu, M.3    Muehlemann, O.4    Moroni, C.5
  • 77
    • 67449132368 scopus 로고    scopus 로고
    • The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis
    • 10.1158/0008-5472.CAN-08-4238 1:CAS:528:DC%2BD1MXnt1equ74%3D 19491267
    • SE Brennan Y Kuwano N Alkharouf PJ Blackshear M Gorospe GM Wilson 2009 The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis Cancer Res 69 5168 5176 10.1158/0008-5472.CAN-08-4238 1:CAS:528:DC%2BD1MXnt1equ74%3D 19491267
    • (2009) Cancer Res , vol.69 , pp. 5168-5176
    • Brennan, S.E.1    Kuwano, Y.2    Alkharouf, N.3    Blackshear, P.J.4    Gorospe, M.5    Wilson, G.M.6
  • 78
    • 10344256186 scopus 로고    scopus 로고
    • 2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR
    • DOI 10.1074/jbc.M407535200
    • X Yang W Wang J Fan A Lal D Yang H Cheng M Gorospe 2004 Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR J Biol Chem 279 49298 49306 10.1074/jbc.M407535200 10.1074/jbc.M407535200 1:CAS:528:DC%2BD2cXpslKis7g%3D 15371446 (Pubitemid 39625816)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49298-49306
    • Yang, X.1    Wang, W.2    Fan, J.3    Lal, A.4    Yang, D.5    Cheng, H.6    Gorospe, M.7
  • 79
    • 73649138927 scopus 로고    scopus 로고
    • Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA
    • 10.3858/emm.2009.41.11.088 1:CAS:528:DC%2BD1MXhsFGqur%2FE 19949288
    • MJ Chae HY Sung EH Kim M Lee H Kwak CH Chae S Kim WY Park 2009 Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA Exp Mol Med 41 824 831 10.3858/emm.2009.41.11.088 1:CAS:528:DC%2BD1MXhsFGqur%2FE 19949288
    • (2009) Exp Mol Med , vol.41 , pp. 824-831
    • Chae, M.J.1    Sung, H.Y.2    Kim, E.H.3    Lee, M.4    Kwak, H.5    Chae, C.H.6    Kim, S.7    Park, W.Y.8
  • 80
    • 0027938267 scopus 로고
    • Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice
    • 10.1093/carcin/15.11.2669 1:CAS:528:DyaK2MXitFyrsrw%3D 7955124
    • K Shimoi S Masuda M Furugori S Esaki N Kinae 1994 Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice Carcinogenesis 15 2669 2672 10.1093/carcin/15.11.2669 1:CAS:528:DyaK2MXitFyrsrw%3D 7955124
    • (1994) Carcinogenesis , vol.15 , pp. 2669-2672
    • Shimoi, K.1    Masuda, S.2    Furugori, M.3    Esaki, S.4    Kinae, N.5
  • 83
    • 38049100559 scopus 로고    scopus 로고
    • An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells
    • 10.1073/pnas.0706641104 1:CAS:528:DC%2BD1cXhs1WmtA%3D%3D 18056640
    • XB Shi L Xue J Yang AH Ma J Zhao M Xu CG Tepper CP Evans HJ Kung RW deVere White 2007 An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells Proc Natl Acad Sci USA 104 19983 19988 10.1073/pnas.0706641104 1:CAS:528:DC%2BD1cXhs1WmtA%3D%3D 18056640
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19983-19988
    • Shi, X.B.1    Xue, L.2    Yang, J.3    Ma, A.H.4    Zhao, J.5    Xu, M.6    Tepper, C.G.7    Evans, C.P.8    Kung, H.J.9    Devere White, R.W.10
  • 84
    • 31044455031 scopus 로고    scopus 로고
    • RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain
    • DOI 10.1261/rna.2258506
    • PT Nelson DA Baldwin WP Kloosterman S Kauppinen RH Plasterk Z Mourelatos 2006 RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain RNA 12 187 191 10.1261/rna.2258506 1:CAS:528:DC%2BD28XhtlSjsrw%3D 16373485 (Pubitemid 43121922)
    • (2006) RNA , vol.12 , Issue.2 , pp. 187-191
    • Nelson, P.T.1    Baldwin, D.A.2    Kloosterman, W.P.3    Kauppinen, S.4    Plasterk, R.H.A.5    Mourelatos, Z.6
  • 87
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • DOI 10.1038/sj.onc.1210293, PII 1210293
    • C Welch Y Chen RL Stallings 2007 MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells Oncogene 26 5017 5022 10.1038/sj.onc.1210293 10.1038/sj.onc.1210293 1:CAS:528: DC%2BD2sXotFygs78%3D 17297439 (Pubitemid 47172643)
    • (2007) Oncogene , vol.26 , Issue.34 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 88
    • 34047270440 scopus 로고    scopus 로고
    • Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    • DOI 10.1158/0008-5472.CAN-06-2698
    • A Gaur DA Jewell Y Liang D Ridzon JH Moore C Chen VR Ambros MA Israel 2007 Characterization of microRNA expression levels and their biological correlates in human cancer cell lines Cancer Res 67 2456 2468 10.1158/0008-5472.CAN-06-2698 10.1158/0008-5472.CAN-06-2698 1:CAS:528: DC%2BD2sXivV2gu78%3D 17363563 (Pubitemid 46548930)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2456-2468
    • Gaur, A.1    Jewell, D.A.2    Liang, Y.3    Ridzon, D.4    Moore, J.H.5    Chen, C.6    Ambros, V.R.7    Israel, M.A.8
  • 89
    • 0034834248 scopus 로고    scopus 로고
    • Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST Data
    • DOI 10.1101/gr.190501
    • E Beaudoing D Gautheret 2001 Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST data Genome Res 11 1520 1526 10.1101/gr.190501 1:CAS:528:DC%2BD3MXmvV2mtrs%3D 11544195 (Pubitemid 32894677)
    • (2001) Genome Research , vol.11 , Issue.9 , pp. 1520-1526
    • Beaudoing, E.1    Gautheret, D.2
  • 90
    • 33646950851 scopus 로고    scopus 로고
    • Biased alternative polyadenylation in human tissues
    • 10.1186/gb-2005-6-12-r100 16356263
    • H Zhang JY Lee B Tian 2005 Biased alternative polyadenylation in human tissues Genome Biol 6 R100 10.1186/gb-2005-6-12-r100 16356263
    • (2005) Genome Biol , vol.6 , pp. 100
    • Zhang, H.1    Lee, J.Y.2    Tian, B.3
  • 91
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • DOI 10.1126/science.1155390
    • R Sandberg JR Neilson A Sarma PA Sharp CB Burge 2008 Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites Science 320 1643 1647 10.1126/science.1155390 1:CAS:528: DC%2BD1cXnt1Oju70%3D 18566288 (Pubitemid 351931255)
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 92
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • 10.1016/j.cell.2009.06.016 1:CAS:528:DC%2BD1MXhsVCjs7rM 19703394
    • C Mayr DP Bartel 2009 Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells Cell 138 673 684 10.1016/j.cell.2009.06.016 1:CAS:528:DC%2BD1MXhsVCjs7rM 19703394
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 93
    • 66049104920 scopus 로고    scopus 로고
    • Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development
    • 10.1073/pnas.0900028106 1:CAS:528:DC%2BD1MXlvFSgtrw%3D 19372383
    • Z Ji JY Lee Z Pan B Jiang B Tian 2009 Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development Proc Natl Acad Sci USA 106 7028 7033 10.1073/pnas. 0900028106 1:CAS:528:DC%2BD1MXlvFSgtrw%3D 19372383
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7028-7033
    • Ji, Z.1    Lee, J.Y.2    Pan, Z.3    Jiang, B.4    Tian, B.5
  • 95
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • DOI 10.1038/ng2003, PII NG2003
    • MS Kumar J Lu KL Mercer TR Golub T Jacks 2007 Impaired microRNA processing enhances cellular transformation and tumorigenesis Nat Genet 39 673 677 10.1038/ng2003 1:CAS:528:DC%2BD2sXksFersLo%3D 17401365 (Pubitemid 46676103)
    • (2007) Nature Genetics , vol.39 , Issue.5 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 96
    • 0024573893 scopus 로고
    • Characterization of the human p53 gene promoter
    • 1:CAS:528:DyaL1MXit1Kntbw%3D 2664471
    • SP Tuck L Crawford 1989 Characterization of the human p53 gene promoter Mol Cell Biol 9 2163 2172 1:CAS:528:DyaL1MXit1Kntbw%3D 2664471
    • (1989) Mol Cell Biol , vol.9 , pp. 2163-2172
    • Tuck, S.P.1    Crawford, L.2
  • 97
    • 33645524978 scopus 로고    scopus 로고
    • Two internal ribosome entry sites mediate the translation of p53 isoforms
    • 10.1038/sj.embor.7400623 1:CAS:528:DC%2BD28XjtV2htL0%3D 16440000
    • PS Ray R Grover S Das 2006 Two internal ribosome entry sites mediate the translation of p53 isoforms EMBO Rep 7 404 410 10.1038/sj.embor.7400623 1:CAS:528:DC%2BD28XjtV2htL0%3D 16440000
    • (2006) EMBO Rep , vol.7 , pp. 404-410
    • Ray, P.S.1    Grover, R.2    Das, S.3


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