Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery

Journal of Medicinal Chemistry

Volumn 58, Issue 20, 2015, Pages 7913-7927

  Narayanan, Sanju ^a   Harris, Danni L ^a   Maitra, Rangan ^a   Runyon, Scott P ^a  

^a RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALANINE; ANGIOTENSIN CONVERTING ENZYME 2; APELIN; APELIN RECEPTOR; APELIN RECEPTOR AGONIST; APELIN RECEPTOR ANTAGONIST; CARDIOVASCULAR AGENT; CYCLOPEPTIDE; UNCLASSIFIED DRUG; APLN PROTEIN, HUMAN; APLNR PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; MOLECULAR LIBRARY; PEPTIDE; SIGNAL PEPTIDE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANGIOGENESIS; APOPTOSIS; ARTICLE; CARDIOVASCULAR DISEASE; CONFORMATIONAL TRANSITION; DRUG BINDING; DRUG EFFECT; DRUG RECEPTOR BINDING; ELIMINATION HALF-LIFE; HEART PROTECTION; HUMAN; MEAN ARTERIAL PRESSURE; NONHUMAN; PATENT; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CARDIOVASCULAR DISEASES; CLINICAL TRIAL (TOPIC); DRUG DEVELOPMENT; DRUG EFFECTS; GENETICS; METABOLISM; MOLECULAR GENETICS; MOLECULAR LIBRARY;

AMINO ACID SEQUENCE; ANIMALS; CARDIOVASCULAR DISEASES; CLINICAL TRIALS AS TOPIC; DRUG DISCOVERY; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDES; RECEPTORS, G-PROTEIN-COUPLED; SMALL MOLECULE LIBRARIES;

EID: 84945373447     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00527     Document Type: Article

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