메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

Apelin-13 enhances arcuate POMC neuron activity via inhibiting M-current

Author keywords

[No Author keywords available]

Indexed keywords

APELIN; APELIN 13; APELIN RECEPTOR; PHOSPHOLIPASE C BETA; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; POTASSIUM CHANNEL KCNQ5; PROOPIOMELANOCORTIN; PROTEIN KINASE; UNCLASSIFIED DRUG; APELIN-13 PEPTIDE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; PERTUSSIS TOXIN; PHOSPHOLIPASE C; SIGNAL PEPTIDE;

EID: 84924940477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119457     Document Type: Article
Times cited : (20)

References (46)
  • 2
    • 20144380036 scopus 로고    scopus 로고
    • Apelin, a newly identified adipokine up-regulated by insulin and obesity
    • Epub 2005/01/29 PMID: 15677759
    • Boucher J, Masri B, Daviaud D, Gesta S, Guigne C, Mazzucotelli A, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology. 2005; 146(4):1764-71. Epub 2005/01/29. doi: 10.1210/en.2004-1427 PMID: 15677759
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1764-1771
    • Boucher, J.1    Masri, B.2    Daviaud, D.3    Gesta, S.4    Guigne, C.5    Mazzucotelli, A.6
  • 3
    • 0037178686 scopus 로고    scopus 로고
    • Apelin-immunoreactivity in the rat hypothalamus and pituitary
    • Epub 2002/07/13. PMID: 12113910
    • Brailoiu GC, Dun SL, Yang J, Ohsawa M, Chang JK, Dun NJ. Apelin-immunoreactivity in the rat hypothalamus and pituitary. Neuroscience letters. 2002; 327(3):193-7. Epub 2002/07/13. PMID: 12113910
    • (2002) Neuroscience Letters , vol.327 , Issue.3 , pp. 193-197
    • Brailoiu, G.C.1    Dun, S.L.2    Yang, J.3    Ohsawa, M.4    Chang, J.K.5    Dun, N.J.6
  • 4
    • 0037008882 scopus 로고    scopus 로고
    • Distribution of apelin-synthesizing neurons in the adult rat brain
    • PMID: 12150785
    • Reaux A, Gallatz K, Palkovits M, Llorens-Cortes C. Distribution of apelin-synthesizing neurons in the adult rat brain. Neuroscience. 2002; 113(3):653-62. PMID: 12150785
    • (2002) Neuroscience , vol.113 , Issue.3 , pp. 653-662
    • Reaux, A.1    Gallatz, K.2    Palkovits, M.3    Llorens-Cortes, C.4
  • 5
    • 84855775145 scopus 로고    scopus 로고
    • Central and peripheral apelin receptor distribution in the mouse: Species differences with rat
    • Epub 2011/12/27 PMID: 22197493
    • Pope GR, Roberts EM, Lolait SJ, O'Carroll AM. Central and peripheral apelin receptor distribution in the mouse: species differences with rat. Peptides. 2012; 33(1):139-48. Epub 2011/12/27. doi: 10.1016/j.peptides.2011.12.005 PMID: 22197493
    • (2012) Peptides , vol.33 , Issue.1 , pp. 139-148
    • Pope, G.R.1    Roberts, E.M.2    Lolait, S.J.3    O'Carroll, A.M.4
  • 6
    • 84876435089 scopus 로고    scopus 로고
    • Hypothalamic survival circuits: Blueprints for purposive behaviors
    • PMID: 23473313
    • Sternson SM. Hypothalamic survival circuits: blueprints for purposive behaviors. Neuron. 2013; 77(5):810-24. doi: 10.1016/j.neuron.2013.02.018 PMID: 23473313
    • (2013) Neuron , vol.77 , Issue.5 , pp. 810-824
    • Sternson, S.M.1
  • 7
    • 79959879208 scopus 로고    scopus 로고
    • Central insulin and leptin-mediated autonomic control of glucose homeostasis. Trends in endocrinology and metabolism
    • PMID: 21489811
    • Marino JS, Xu Y, Hill JW. Central insulin and leptin-mediated autonomic control of glucose homeostasis. Trends in endocrinology and metabolism: TEM. 2011; 22(7):275-85. doi: 10.1016/j.tem.2011.03.001 PMID: 21489811
    • (2011) TEM , vol.22 , Issue.7 , pp. 275-285
    • Marino, J.S.1    Xu, Y.2    Hill, J.W.3
  • 8
    • 79961191336 scopus 로고    scopus 로고
    • Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice
    • Duparc T, Colom A, Cani PD, Massaly N, Rastrelli S, Drougard A, et al. Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice. Antioxidants & redox signaling. 2011; 15(6):1477-96. doi: 10.1089/ars.2010.3454.
    • (2011) Antioxidants & Redox Signaling , vol.15 , Issue.6 , pp. 1477-1496
    • Duparc, T.1    Colom, A.2    Cani, P.D.3    Massaly, N.4    Rastrelli, S.5    Drougard, A.6
  • 9
    • 58349120831 scopus 로고    scopus 로고
    • Diminished metabolic responses to centrally-administered apelin-13 in diet-induced obese rats fed a high-fat diet
    • PMID: 19076266
    • Clarke KJ, Whitaker KW, Reyes TM. Diminished metabolic responses to centrally-administered apelin-13 in diet-induced obese rats fed a high-fat diet. Journal of neuroendocrinology. 2009; 21(2):83-9. doi: 10.1111/j.1365-2826.2008.01815.x PMID: 19076266
    • (2009) Journal of Neuroendocrinology , vol.21 , Issue.2 , pp. 83-89
    • Clarke, K.J.1    Whitaker, K.W.2    Reyes, T.M.3
  • 10
    • 0345714715 scopus 로고    scopus 로고
    • Intracerebroventricular injection of apelin-13 reduces food intake in the rat
    • Epub 2003/12/04. PMID: 14642423
    • Sunter D, Hewson AK, Dickson SL. Intracerebroventricular injection of apelin-13 reduces food intake in the rat. Neuroscience letters. 2003; 353(1):1-4. Epub 2003/12/04. PMID: 14642423
    • (2003) Neuroscience Letters , vol.353 , Issue.1 , pp. 1-4
    • Sunter, D.1    Hewson, A.K.2    Dickson, S.L.3
  • 11
    • 33746299000 scopus 로고    scopus 로고
    • Integration of metabolic stimuli in the hypothalamic arcuate nucleus
    • PMID: 16876573
    • van den Top M, Spanswick D. Integration of metabolic stimuli in the hypothalamic arcuate nucleus. Progress in brain research. 2006; 153:141-54. doi: 10.1016/S0079-6123(06)53008-0 PMID: 16876573
    • (2006) Progress in Brain Research , vol.153 , pp. 141-154
    • Van Den Top, M.1    Spanswick, D.2
  • 13
    • 0035015269 scopus 로고    scopus 로고
    • Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
    • PMID: 11359874
    • Reaux A, De Mota N, Skultetyova I, Lenkei Z, El Messari S, Gallatz K, et al. Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain. Journal of neurochemistry. 2001; 77(4):1085-96. PMID: 11359874
    • (2001) Journal of Neurochemistry , vol.77 , Issue.4 , pp. 1085-1096
    • Reaux, A.1    De Mota, N.2    Skultetyova, I.3    Lenkei, Z.4    El Messari, S.5    Gallatz, K.6
  • 15
    • 0037032005 scopus 로고    scopus 로고
    • Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility
    • PMID: 12215493
    • Szokodi I, Tavi P, Foldes G, Voutilainen-Myllyla S, Ilves M, Tokola H, et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circulation research. 2002; 91(5):434-40. PMID: 12215493
    • (2002) Circulation Research , vol.91 , Issue.5 , pp. 434-440
    • Szokodi, I.1    Tavi, P.2    Foldes, G.3    Voutilainen-Myllyla, S.4    Ilves, M.5    Tokola, H.6
  • 16
    • 84892932862 scopus 로고    scopus 로고
    • Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes
    • Epub 2013/07/25
    • Drougard A, Duparc T, Brenachot X, Carneiro L, Gouaze A, Fournel A, et al. Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes. Antioxidants & redox signaling. 2014; 20(4):557-73. Epub 2013/07/25. doi: 10.1089/ars.2013.5182.
    • (2014) Antioxidants & Redox Signaling , vol.20 , Issue.4 , pp. 557-573
    • Drougard, A.1    Duparc, T.2    Brenachot, X.3    Carneiro, L.4    Gouaze, A.5    Fournel, A.6
  • 17
    • 84897507249 scopus 로고    scopus 로고
    • Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels
    • PMID: 24703699
    • Qiu J, Zhang C, Borgquist A, Nestor CC, Smith AW, Bosch MA, et al. Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels. Cell metabolism. 2014; 19(4):682-93. doi: 10.1016/j.cmet.2014.03.004 PMID: 24703699
    • (2014) Cell Metabolism , vol.19 , Issue.4 , pp. 682-693
    • Qiu, J.1    Zhang, C.2    Borgquist, A.3    Nestor, C.C.4    Smith, A.W.5    Bosch, M.A.6
  • 19
    • 80052496920 scopus 로고    scopus 로고
    • Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity
    • Epub 2011/08/30 PMID: 21873987
    • Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, et al. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nature medicine. 2011; 17(9):1121-7. Epub 2011/08/30. doi: 10.1038/nm.2421 PMID: 21873987
    • (2011) Nature Medicine , vol.17 , Issue.9 , pp. 1121-1127
    • Diano, S.1    Liu, Z.W.2    Jeong, J.K.3    Dietrich, M.O.4    Ruan, H.B.5    Kim, E.6
  • 20
    • 84255192924 scopus 로고    scopus 로고
    • Endogenous BDNF regulates inhibitory synaptic transmission in the ventromedial nucleus of the hypothalamus
    • PMID: 21994261
    • Jo YH. Endogenous BDNF regulates inhibitory synaptic transmission in the ventromedial nucleus of the hypothalamus. Journal of neurophysiology. 2012; 107(1):42-9. doi: 10.1152/jn.00353.2011 PMID: 21994261
    • (2012) Journal of Neurophysiology , vol.107 , Issue.1 , pp. 42-49
    • Jo, Y.H.1
  • 21
    • 0025774354 scopus 로고
    • Liquid junction potentials and small cell effects in patch-clamp analysis
    • PMID: 1715403
    • Barry PH, Lynch JW. Liquid junction potentials and small cell effects in patch-clamp analysis. The Journal of membrane biology. 1991; 121(2):101-17. PMID: 1715403
    • (1991) The Journal of Membrane Biology , vol.121 , Issue.2 , pp. 101-117
    • Barry, P.H.1    Lynch, J.W.2
  • 23
    • 84861879399 scopus 로고    scopus 로고
    • Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons
    • PMID: 22436698
    • Roepke TA, Smith AW, Ronnekleiv OK, Kelly MJ. Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. American journal of physiology Endocrinology and metabolism. 2012; 302(11):E1399-406. doi: 10.1152/ajpendo.00565.2011 PMID: 22436698
    • (2012) American Journal of Physiology Endocrinology and Metabolism , vol.302 , Issue.11 , pp. E1399-E1406
    • Roepke, T.A.1    Smith, A.W.2    Ronnekleiv, O.K.3    Kelly, M.J.4
  • 24
    • 0030106244 scopus 로고    scopus 로고
    • Intracerebroventricular pertussis toxin enhances sensitivity to chemical convulsants and decreases the protective efficacy of carbamazepine in mice
    • PMID: 8880893
    • Korolkiewicz R, Kleinrok Z, Mlynarczyk M. Intracerebroventricular pertussis toxin enhances sensitivity to chemical convulsants and decreases the protective efficacy of carbamazepine in mice. Pharmacological research: the official journal of the Italian Pharmacological Society. 1996; 33(3):211-5. doi: 10.1006/phrs.1996.0029 PMID: 8880893
    • (1996) Pharmacological Research: The Official Journal of the Italian Pharmacological Society , vol.33 , Issue.3 , pp. 211-215
    • Korolkiewicz, R.1    Kleinrok, Z.2    Mlynarczyk, M.3
  • 25
    • 0027163363 scopus 로고
    • Modification of morphine-induced locomotor activity by pertussis toxin: Biochemical and behavioral studies in mice
    • PMID: 8397054
    • Funada M, Suzuki T, Narita M, Misawa M, Nagase H. Modification of morphine-induced locomotor activity by pertussis toxin: biochemical and behavioral studies in mice. Brain research. 1993; 619(1-2):163-72. PMID: 8397054
    • (1993) Brain Research , vol.619 , Issue.1-2 , pp. 163-172
    • Funada, M.1    Suzuki, T.2    Narita, M.3    Misawa, M.4    Nagase, H.5
  • 26
    • 33644839086 scopus 로고    scopus 로고
    • Involvement of cAMP/cAMP-dependent protein kinase signaling pathway in regulation of Na+,K+-ATPase upon activation of opioid receptors by morphine
    • PMID: 16317112
    • Wu ZQ, Li M, Chen J, Chi ZQ, Liu JG. Involvement of cAMP/cAMP-dependent protein kinase signaling pathway in regulation of Na+,K+-ATPase upon activation of opioid receptors by morphine. Molecular pharmacology. 2006; 69(3):866-76. doi: 10.1124/mol.105.016501 PMID: 16317112
    • (2006) Molecular Pharmacology , vol.69 , Issue.3 , pp. 866-876
    • Wu, Z.Q.1    Li, M.2    Chen, J.3    Chi, Z.Q.4    Liu, J.G.5
  • 28
    • 84884180829 scopus 로고    scopus 로고
    • The apelin receptor APJ: Journey from an orphan to a multifaceted regulator of homeostasis
    • PMID: 23943882
    • O'Carroll AM, Lolait SJ, Harris LE, Pope GR. The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis. The Journal of endocrinology. 2013; 219(1):R13-35. doi: 10.1530/JOE-13-0227 PMID: 23943882
    • (2013) The Journal of Endocrinology , vol.219 , Issue.1 , pp. R13-R35
    • O'Carroll, A.M.1    Lolait, S.J.2    Harris, L.E.3    Pope, G.R.4
  • 30
    • 0031051444 scopus 로고    scopus 로고
    • Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins
    • PMID: 9032437
    • Fields TA, Casey PJ. Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins. The Biochemical journal. 1997; 321 (Pt 3):561-71. PMID: 9032437
    • (1997) The Biochemical Journal , vol.321 , Issue.3 , pp. 561-571
    • Fields, T.A.1    Casey, P.J.2
  • 31
    • 42249116015 scopus 로고    scopus 로고
    • Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair
    • PMID: 18402935
    • Nelson TJ, Sun MK, Hongpaisan J, Alkon DL. Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair. European journal of pharmacology. 2008; 585(1):76-87. doi: 10.1016/j.ejphar.2008.01.051 PMID: 18402935
    • (2008) European Journal of Pharmacology , vol.585 , Issue.1 , pp. 76-87
    • Nelson, T.J.1    Sun, M.K.2    Hongpaisan, J.3    Alkon, D.L.4
  • 32
    • 0026676807 scopus 로고
    • Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C
    • Epub 1992/12/17 PMID: 1465134
    • Katz A, Wu D, Simon MI. Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C. Nature. 1992; 360(6405):686-9. Epub 1992/12/17. doi: 10.1038/360686a0 PMID: 1465134
    • (1992) Nature , vol.360 , Issue.6405 , pp. 686-689
    • Katz, A.1    Wu, D.2    Simon, M.I.3
  • 33
    • 0027495684 scopus 로고
    • New roles for G-protein beta gamma-dimers in transmembrane signalling
    • Epub 1993/09/30 PMID: 8413584
    • Clapham DE, Neer EJ. New roles for G-protein beta gamma-dimers in transmembrane signalling. Nature. 1993; 365(6445):403-6. Epub 1993/09/30. doi: 10.1038/365403a0 PMID: 8413584
    • (1993) Nature , vol.365 , Issue.6445 , pp. 403-406
    • Clapham, D.E.1    Neer, E.J.2
  • 34
    • 0027178468 scopus 로고
    • Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein
    • Epub 1993/06/01. PMID: 8389480
    • Wu D, Katz A, Simon MI. Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 1993; 90(11):5297-301. Epub 1993/06/01. PMID: 8389480
    • (1993) Proceedings of the National Academy of Sciences of the United States of America , vol.90 , Issue.11 , pp. 5297-5301
    • Wu, D.1    Katz, A.2    Simon, M.I.3
  • 35
    • 0034929557 scopus 로고    scopus 로고
    • KCNQ potassium channels: Physiology, pathophysiology, and pharmacology
    • Robbins J. KCNQ potassium channels: physiology, pathophysiology, and pharmacology. Pharmacology & therapeutics. 2001; 90(1):1-19.
    • (2001) Pharmacology & therapeutics , vol.90 , Issue.1 , pp. 1-19
    • Robbins, J.1
  • 36
    • 27644518764 scopus 로고    scopus 로고
    • Pathways modulating neural KCNQ/M (Kv7) potassium channels
    • PMID: 16261179
    • Delmas P, Brown DA. Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nature reviews Neuroscience. 2005; 6(11):850-62. doi: 10.1038/nrn1785 PMID: 16261179
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.11 , pp. 850-862
    • Delmas, P.1    Brown, D.A.2
  • 37
    • 70350303335 scopus 로고    scopus 로고
    • Kv7/KCNQ channels control action potential phasing of pyramidal neurons during hippocampal gamma oscillations in vitro
    • PMID: 19846723
    • Leao RN, Tan HM, Fisahn A. Kv7/KCNQ channels control action potential phasing of pyramidal neurons during hippocampal gamma oscillations in vitro. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2009; 29(42):13353-64. doi: 10.1523/JNEUROSCI.1463-09.2009 PMID: 19846723
    • (2009) The Journal of Neuroscience: The Official Journal of the Society for Neuroscience , vol.29 , Issue.42 , pp. 13353-13364
    • Leao, R.N.1    Tan, H.M.2    Fisahn, A.3
  • 38
    • 34548604499 scopus 로고    scopus 로고
    • Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
    • PMID: 17728716
    • Parton LE, Ye CP, Coppari R, Enriori PJ, Choi B, Zhang CY, et al. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature. 2007; 449(7159):228-32. doi: 10.1038/nature06098 PMID: 17728716
    • (2007) Nature , vol.449 , Issue.7159 , pp. 228-232
    • Parton, L.E.1    Ye, C.P.2    Coppari, R.3    Enriori, P.J.4    Choi, B.5    Zhang, C.Y.6
  • 39
    • 0035942777 scopus 로고    scopus 로고
    • Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
    • PMID: 11373681
    • Cowley MA, Smart JL, Rubinstein M, Cerdan MG, Diano S, Horvath TL, et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 2001; 411(6836):480-4. doi: 10.1038/35078085 PMID: 11373681
    • (2001) Nature , vol.411 , Issue.6836 , pp. 480-484
    • Cowley, M.A.1    Smart, J.L.2    Rubinstein, M.3    Cerdan, M.G.4    Diano, S.5    Horvath, T.L.6
  • 41
    • 33745819212 scopus 로고    scopus 로고
    • Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
    • PMID: 16794735
    • Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Munzberg H, et al. Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. The Journal of clinical investigation. 2006; 116(7):1886-901. doi: 10.1172/JCI27123 PMID: 16794735
    • (2006) The Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1886-1901
    • Plum, L.1    Ma, X.2    Hampel, B.3    Balthasar, N.4    Coppari, R.5    Munzberg, H.6
  • 42
    • 79961180328 scopus 로고    scopus 로고
    • Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels
    • PMID: 21835345
    • Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 2011; 71(3):488-97. doi: 10.1016/j.neuron.2011.06.012 PMID: 21835345
    • (2011) Neuron , vol.71 , Issue.3 , pp. 488-497
    • Sohn, J.W.1    Xu, Y.2    Jones, J.E.3    Wickman, K.4    Williams, K.W.5    Elmquist, J.K.6
  • 43
    • 0026497385 scopus 로고
    • Regulation of phospholipase C by G proteins
    • PMID: 1335185
    • Sternweis PC, Smrcka AV. Regulation of phospholipase C by G proteins. Trends in biochemical sciences. 1992; 17(12):502-6. PMID: 1335185
    • (1992) Trends in Biochemical Sciences , vol.17 , Issue.12 , pp. 502-506
    • Sternweis, P.C.1    Smrcka, A.V.2
  • 44
    • 70350389400 scopus 로고    scopus 로고
    • Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons
    • PMID: 19883613
    • Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, et al. Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell metabolism. 2009; 10(5):343-54. doi: 10.1016/j.cmet.2009.09.008 PMID: 19883613
    • (2009) Cell Metabolism , vol.10 , Issue.5 , pp. 343-354
    • Al-Qassab, H.1    Smith, M.A.2    Irvine, E.E.3    Guillermet-Guibert, J.4    Claret, M.5    Choudhury, A.I.6
  • 45
    • 34547651092 scopus 로고    scopus 로고
    • AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
    • PMID: 17671657
    • Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, et al. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. The Journal of clinical investigation. 2007; 117(8):2325-36. doi: 10.1172/JCI31516 PMID: 17671657
    • (2007) The Journal of Clinical Investigation , vol.117 , Issue.8 , pp. 2325-2336
    • Claret, M.1    Smith, M.A.2    Batterham, R.L.3    Selman, C.4    Choudhury, A.I.5    Fryer, L.G.6
  • 46
    • 84863267488 scopus 로고    scopus 로고
    • Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
    • PMID: 22326958
    • Berglund ED, Vianna CR, Donato J Jr, Kim MH, Chuang JC, Lee CE, et al. Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice. The Journal of clinical investigation. 2012; 122(3):1000-9. doi: 10.1172/JCI59816 PMID: 22326958
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.3 , pp. 1000-1009
    • Berglund, E.D.1    Vianna, C.R.2    Donato, J.3    Kim, M.H.4    Chuang, J.C.5    Lee, C.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.