Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist

FASEB Journal

Volumn 24, Issue 5, 2010, Pages 1506-1517

  Iturrioz, Xavier ^a   Alvear Perez, Rodrigo ^a   De Mota, Nadia ^a   Franchet, Christel ^b,d   Guillier, Fabrice ^b   Leroux, Vincent ^c   Dabire, Hubert ^a   Jouan, Melissande Le ^a   Chabane, Hadjila ^b   Gerbier, Romain ^a   Bonnet, Dominique ^b   Berdeaux, Alain ^a   Maigret, Bernard ^c   Galzi, Jean Luc ^b   Hibert, Marcel ^b   Llorens Cortes, Catherine ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c CNRS   (France)

^d BioParc Bld Sebastien Brandt   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APELIN RECEPTOR; CYCLIC AMP; E 339 3 D6; FLUORESCENT DYE; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; NORADRENALIN; UNCLASSIFIED DRUG; VASODILATOR AGENT; VASOPRESSIN; AGTRL1 PROTEIN, HUMAN; DIPEPTIDE; E339 3D6 COMPOUND; E339-3D6 COMPOUND; FLUORESCEIN DERIVATIVE; VASOPRESSIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG MECHANISM; ENERGY TRANSFER; FLUORESCENCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION; VASOPRESSIN RELEASE; ANIMAL; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; WISTAR KYOTO RAT;

MUS; RATTUS;

ANIMALS; AORTA; CYCLIC AMP; DIPEPTIDES; DRUG EVALUATION, PRECLINICAL; FLUORESCEINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FORSKOLIN; HUMANS; MALE; MICE; RATS; RATS, INBRED WKY; RECEPTORS, G-PROTEIN-COUPLED; VASODILATION; VASOPRESSINS;

EID: 77952296548     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-140715     Document Type: Article

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