-
1
-
-
58849085018
-
Pulmonary veno-occlusive disease
-
Montani D, Price LC, Dorfmuller P, Achouh L, Jaïs X, Yaïci A, Sitbon O, Musset D, Simonneau G, Humbert M. Pulmonary veno-occlusive disease. Eur Respir J. 2009;33:189-200.
-
(2009)
Eur Respir J.
, vol.33
, pp. 189-200
-
-
Montani, D.1
Price, L.C.2
Dorfmuller, P.3
Achouh, L.4
Jaïs, X.5
Yaïci, A.6
Sitbon, O.7
Musset, D.8
Simonneau, G.9
Humbert, M.10
-
2
-
-
74049095508
-
ERG is required for the differentiation of embryonic stem cells along the endothelial lineage
-
Nikolova-Krstevski V, Yuan L, Le Bras A, Vijayaraj P, Kondo M, Gebauer I, Bhasin M, Carman CV, Oettgen P. ERG is required for the differentiation of embryonic stem cells along the endothelial lineage. BMC Dev Biol. 2009;9:72.
-
(2009)
BMC Dev Biol
, vol.9
, pp. 72
-
-
Nikolova-Krstevski, V.1
Yuan, L.2
Le Bras, A.3
Vijayaraj, P.4
Kondo, M.5
Gebauer, I.6
Bhasin, M.7
Carman, C.V.8
Oettgen, P.9
-
3
-
-
45549102935
-
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells
-
Loughran SJ, Kruse EA, Hacking DF, de Graaf CA, Hyland CD, Willson TA, Henley KJ, Ellis S, Voss AK, Metcalf D, Hilton DJ, Alexander WS, Kile BT. The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nat Immunol. 2008;9:810-819.
-
(2008)
Nat Immunol
, vol.9
, pp. 810-819
-
-
Loughran, S.J.1
Kruse, E.A.2
Hacking, D.F.3
De Graaf, C.A.4
Hyland, C.D.5
Willson, T.A.6
Henley, K.J.7
Ellis, S.8
Voss, A.K.9
Metcalf, D.10
Hilton, D.J.11
Alexander, W.S.12
Kile, B.T.13
-
4
-
-
0035760290
-
Combined genomic and antisense analysis reveals that the transcription factor Erg is implicated in endothelial cell differentiation
-
McLaughlin F, Ludbrook VJ, Cox J, von Carlowitz I, Brown S, Randi AM. Combined genomic and antisense analysis reveals that the transcription factor Erg is implicated in endothelial cell differentiation. Blood. 2001;98:3332-3339.
-
(2001)
Blood
, vol.98
, pp. 3332-3339
-
-
McLaughlin, F.1
Ludbrook, V.J.2
Cox, J.3
Von Carlowitz, I.4
Brown, S.5
Randi, A.M.6
-
5
-
-
78650885048
-
The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells
-
Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM, Randi AM. The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells. Arterioscler Thromb Vasc Biol. 2011;31:142-150.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 142-150
-
-
Sperone, A.1
Dryden, N.H.2
Birdsey, G.M.3
Madden, L.4
Johns, M.5
Evans, P.C.6
Mason, J.C.7
Haskard, D.O.8
Boyle, J.J.9
Paleolog, E.M.10
Randi, A.M.11
-
6
-
-
66149106668
-
Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene
-
Yuan L, Nikolova-Krstevski V, Zhan Y, Kondo M, Bhasin M, Varghese L, Yano K, Carman CV, Aird WC, Oettgen P. Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. Circ Res. 2009;104:1049-1057.
-
(2009)
Circ Res
, vol.104
, pp. 1049-1057
-
-
Yuan, L.1
Nikolova-Krstevski, V.2
Zhan, Y.3
Kondo, M.4
Bhasin, M.5
Varghese, L.6
Yano, K.7
Carman, C.V.8
Aird, W.C.9
Oettgen, P.10
-
7
-
-
0032755112
-
Xl erg: Expression pattern and overexpression during development plead for a role in endothelial cell differentiation
-
Baltzinger M, Mager-Heckel AM, Remy P. Xl erg: expression pattern and overexpression during development plead for a role in endothelial cell differentiation. Dev Dyn. 1999;216:420-433.
-
(1999)
Dev Dyn
, vol.216
, pp. 420-433
-
-
Baltzinger, M.1
Mager-Heckel, A.M.2
Remy, P.3
-
8
-
-
4644320632
-
Apelin has in vivo inotropic effects on normal and failing hearts
-
Berry MF, Pirolli TJ, Jayasankar V, Burdick J, Morine KJ, Gardner TJ, Woo YJ. Apelin has in vivo inotropic effects on normal and failing hearts. Circulation. 2004;110(suppl 1):II187-II193.
-
(2004)
Circulation
, vol.110
, pp. II187-II193
-
-
Berry, M.F.1
Pirolli, T.J.2
Jayasankar, V.3
Burdick, J.4
Morine, K.J.5
Gardner, T.J.6
Woo, Y.J.7
-
9
-
-
33744816839
-
Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure
-
Chong KS, Gardner RS, Morton JJ, Ashley EA, McDonagh TA. Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure. Eur J Heart Fail. 2006;8:355-360.
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 355-360
-
-
Chong, K.S.1
Gardner, R.S.2
Morton, J.J.3
Ashley, E.A.4
McDonagh, T.A.5
-
10
-
-
0041696762
-
The msr/apj gene encoding the apelin receptor is an early and specific marker of the venous phenotype in the retinal vasculature
-
Saint-Geniez M, Argence CB, Knibiehler B, Audigier Y. The msr/apj gene encoding the apelin receptor is an early and specific marker of the venous phenotype in the retinal vasculature. Gene Expr Patterns. 2003;3:467-472.
-
(2003)
Gene Expr Patterns
, vol.3
, pp. 467-472
-
-
Saint-Geniez, M.1
Argence, C.B.2
Knibiehler, B.3
Audigier, Y.4
-
11
-
-
0037868944
-
Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats
-
Cheng X, Cheng XS, Pang CC. Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats. Eur J Pharmacol. 2003;470:171-175.
-
(2003)
Eur J Pharmacol
, vol.470
, pp. 171-175
-
-
Cheng, X.1
Cheng, X.S.2
Pang, C.C.3
-
12
-
-
33745947584
-
Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo
-
Cox CM, D'Agostino SL, Miller MK, Heimark RL, Krieg PA. Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo. Dev Biol. 2006;296:177-189.
-
(2006)
Dev Biol
, vol.296
, pp. 177-189
-
-
Cox, C.M.1
D'Agostino, S.L.2
Miller, M.K.3
Heimark, R.L.4
Krieg, P.A.5
-
13
-
-
50949099615
-
Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis
-
Eyries M, Siegfried G, Ciumas M, Montagne K, Agrapart M, Lebrin F, Soubrier F. Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res. 2008;103:432-440.
-
(2008)
Circ Res
, vol.103
, pp. 432-440
-
-
Eyries, M.1
Siegfried, G.2
Ciumas, M.3
Montagne, K.4
Agrapart, M.5
Lebrin, F.6
Soubrier, F.7
-
14
-
-
70449109145
-
Notch3 signaling promotes the development of pulmonary arterial hypertension
-
Li X, Zhang X, Leathers R, Makino A, Huang C, Parsa P, Macias J, Yuan JX, Jamieson SW, Thistlethwaite PA. Notch3 signaling promotes the development of pulmonary arterial hypertension. Nat Med. 2009;15:1289-1297.
-
(2009)
Nat Med
, vol.15
, pp. 1289-1297
-
-
Li, X.1
Zhang, X.2
Leathers, R.3
Makino, A.4
Huang, C.5
Parsa, P.6
Macias, J.7
Yuan, J.X.8
Jamieson, S.W.9
Thistlethwaite, P.A.10
-
15
-
-
14644406264
-
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors
-
Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005;166:913-921.
-
(2005)
Am J Pathol
, vol.166
, pp. 913-921
-
-
Schacht, V.1
Dadras, S.S.2
Johnson, L.A.3
Jackson, D.G.4
Hong, Y.K.5
Detmar, M.6
-
16
-
-
71049164323
-
Goal-oriented therapy in pulmonary veno-occlusive disease: A word of caution
-
Montani D, Jaïs X, Dorfmuller P, Simonneau G, Sitbon O, Humbert M. Goal-oriented therapy in pulmonary veno-occlusive disease: a word of caution. Eur Respir J. 2009;34:1204-1206.
-
(2009)
Eur Respir J.
, vol.34
, pp. 1204-1206
-
-
Montani, D.1
Jaïs, X.2
Dorfmuller, P.3
Simonneau, G.4
Sitbon, O.5
Humbert, M.6
-
17
-
-
79551585898
-
ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification
-
Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev. 2011;25:251-262.
-
(2011)
Genes Dev
, vol.25
, pp. 251-262
-
-
Taoudi, S.1
Bee, T.2
Hilton, A.3
Knezevic, K.4
Scott, J.5
Willson, T.A.6
Collin, C.7
Thomas, T.8
Voss, A.K.9
Kile, B.T.10
Alexander, W.S.11
Pimanda, J.E.12
Hilton, D.J.13
-
18
-
-
77955655868
-
Hemodynamic effect of apelin in a canine model of acute pulmonary thromboembolism
-
Feng JH, Li WM, Wu XP, Tan XY, Gao YH, Han CL, Li SQ, Xie HN. Hemodynamic effect of apelin in a canine model of acute pulmonary thromboembolism. Peptides. 2010;31:1772-1778.
-
(2010)
Peptides
, vol.31
, pp. 1772-1778
-
-
Feng, J.H.1
Li, W.M.2
Wu, X.P.3
Tan, X.Y.4
Gao, Y.H.5
Han, C.L.6
Li, S.Q.7
Xie, H.N.8
-
19
-
-
34249855545
-
From the archives of the AFIP: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis
-
Frazier AA, Franks TJ, Mohammed TL, Ozbudak IH, Galvin JR. From the archives of the AFIP: pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis. Radiographics. 2007;27:867-882.
-
(2007)
Radiographics
, vol.27
, pp. 867-882
-
-
Frazier, A.A.1
Franks, T.J.2
Mohammed, T.L.3
Ozbudak, I.H.4
Galvin, J.R.5
-
20
-
-
11144356184
-
The endothelial- cell-derived secreted factor Egfl7 regulates vascular tube formation
-
Parker LH, Schmidt M, Jin SW, Gray AM, Beis D, Pham T, Frantz G, Palmieri S, Hillan K, Stainier DY, De Sauvage FJ, Ye W. The endothelial- cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature. 2004;428:754-758.
-
(2004)
Nature
, vol.428
, pp. 754-758
-
-
Parker, L.H.1
Schmidt, M.2
Jin, S.W.3
Gray, A.M.4
Beis, D.5
Pham, T.6
Frantz, G.7
Palmieri, S.8
Hillan, K.9
Stainier, D.Y.10
De Sauvage, F.J.11
Ye, W.12
-
21
-
-
78650652062
-
Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7
-
Nichol D, Shawber C, Fitch MJ, Bambino K, Sharma A, Kitajewski J, Stuhlmann H. Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7. Blood. 2010;116:6133-6143.
-
(2010)
Blood
, vol.116
, pp. 6133-6143
-
-
Nichol, D.1
Shawber, C.2
Fitch, M.J.3
Bambino, K.4
Sharma, A.5
Kitajewski, J.6
Stuhlmann, H.7
-
22
-
-
50349086725
-
Vascular effects of apelin in vivo in man
-
Japp AG, Cruden NL, Amer DA, Li VK, Goudie EB, Johnston NR, Sharma S, Neilson I, Webb DJ, Megson IL, Flapan AD, Newby DE. Vascular effects of apelin in vivo in man. J Am Coll Cardiol. 2008;52:908-913.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 908-913
-
-
Japp, A.G.1
Cruden, N.L.2
Amer, D.A.3
Li, V.K.4
Goudie, E.B.5
Johnston, N.R.6
Sharma, S.7
Neilson, I.8
Webb, D.J.9
Megson, I.L.10
Flapan, A.D.11
Newby, D.E.12
-
23
-
-
55849094397
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
-
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest. 2008;118:3343-3354.
-
(2008)
J Clin Invest
, vol.118
, pp. 3343-3354
-
-
Chun, H.J.1
Ali, Z.A.2
Kojima, Y.3
Kundu, R.K.4
Sheikh, A.Y.5
Agrawal, R.6
Zheng, L.7
Leeper, N.J.8
Pearl, N.E.9
Patterson, A.J.10
Anderson, J.P.11
Tsao, P.S.12
Lenardo, M.J.13
Ashley, E.A.14
Quertermous, T.15
-
24
-
-
80052348254
-
Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
-
Alastalo TP, Li M, Perez Vde J, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival. J Clin Invest. 2011;121:3735-3746.
-
(2011)
J Clin Invest
, vol.121
, pp. 3735-3746
-
-
Alastalo, T.P.1
Li, M.2
Perez Vde, J.3
Pham, D.4
Sawada, H.5
Wang, J.K.6
Koskenvuo, M.7
Wang, L.8
Freeman, B.A.9
Chang, H.Y.10
Rabinovitch, M.11
-
25
-
-
70350462121
-
Endogenous regulation of cardiovascular function by apelin-APJ
-
Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol. 2009;297:H1904-H1913.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, pp. H1904-H1913
-
-
Charo, D.N.1
Ho, M.2
Fajardo, G.3
Kawana, M.4
Kundu, R.K.5
Sheikh, A.Y.6
Finsterbach, T.P.7
Leeper, N.J.8
Ernst, K.V.9
Chen, M.M.10
Ho, Y.D.11
Chun, H.J.12
Bernstein, D.13
Ashley, E.A.14
Quertermous, T.15
-
26
-
-
33847176664
-
The G protein-coupled receptor Agtrl1b regulates early development of myocardial progenitors
-
Scott IC, Masri B, D'Amico LA, Jin SW, Jungblut B, Wehman AM, Baier H, Audigier Y, Stainier DY. The G protein-coupled receptor Agtrl1b regulates early development of myocardial progenitors. Dev Cell. 2007;12:403-413.
-
(2007)
Dev Cell
, vol.12
, pp. 403-413
-
-
Scott, I.C.1
Masri, B.2
D'Amico, L.A.3
Jin, S.W.4
Jungblut, B.5
Wehman, A.M.6
Baier, H.7
Audigier, Y.8
Stainier, D.Y.9
-
27
-
-
82755165210
-
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension
-
Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, Dumur CI, Fawcett P, Voelkel NF, Natarajan R. Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. Am J Respir Cell Mol Biol. 2011;45:1239-1247.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1239-1247
-
-
Drake, J.I.1
Bogaard, H.J.2
Mizuno, S.3
Clifton, B.4
Xie, B.5
Gao, Y.6
Dumur, C.I.7
Fawcett, P.8
Voelkel, N.F.9
Natarajan, R.10
-
28
-
-
66949148740
-
Apelin decreases myocardial injury and improves right ventricular function in monocrotalineinduced pulmonary hypertension
-
Falcão-Pires I, Gonçalves N, Henriques-Coelho T, Moreira-Gonçalves D, Roncon-Albuquerque R Jr, Leite-Moreira AF. Apelin decreases myocardial injury and improves right ventricular function in monocrotalineinduced pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2009;296:H2007-H2014.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
, pp. H2007-H2014
-
-
Falcão-Pires, I.1
Gonçalves, N.2
Henriques-Coelho, T.3
Moreira-Gonçalves, D.4
Roncon-Albuquerque, R.5
Leite-Moreira, A.F.6
-
29
-
-
84891373442
-
EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
-
Eyries M, Montani D, Girerd B, Perret C, Leroy A, Lonjou C, Chelghoum N, Coulet F, Bonnet D, Dorfmüller P, Fadel E, Sitbon O, Simonneau G, Tregouët DA, Humbert M, Soubrier F. EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension. Nat Genet. 2014;46:65-69.
-
(2014)
Nat Genet
, vol.46
, pp. 65-69
-
-
Eyries, M.1
Montani, D.2
Girerd, B.3
Perret, C.4
Leroy, A.5
Lonjou, C.6
Chelghoum, N.7
Coulet, F.8
Bonnet, D.9
Dorfmüller, P.10
Fadel, E.11
Sitbon, O.12
Simonneau, G.13
Tregouët, D.A.14
Humbert, M.15
Soubrier, F.16
-
30
-
-
84893709864
-
EIF2AK4 mutations in pulmonary capillary hemangiomatosis
-
Best DH, Sumner KL, Austin ED, Chung WK, Brown LM, Borczuk AC, Rosenzweig EB, Bayrak-Toydemir P, Mao R, Cahill BC, Tazelaar HD, Leslie KO, Hemnes AR, Robbins IM, Elliott CG. EIF2AK4 mutations in pulmonary capillary hemangiomatosis. Chest. 2014;145:231-236.
-
(2014)
Chest
, vol.145
, pp. 231-236
-
-
Best, D.H.1
Sumner, K.L.2
Austin, E.D.3
Chung, W.K.4
Brown, L.M.5
Borczuk, A.C.6
Rosenzweig, E.B.7
Bayrak-Toydemir, P.8
Mao, R.9
Cahill, B.C.10
Tazelaar, H.D.11
Leslie, K.O.12
Hemnes, A.R.13
Robbins, I.M.14
Elliott, C.G.15
-
31
-
-
0001598487
-
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
-
Berlanga JJ, Santoyo J, De Haro C. Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase. Eur J Biochem. 1999;265:754-762.
-
(1999)
Eur J Biochem
, vol.265
, pp. 754-762
-
-
Berlanga, J.J.1
Santoyo, J.2
De Haro, C.3
|