Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice

Journal of Biomedical Science

Volumn 22, Issue 1, 2015, Pages

  Porto, Marcella L ^a   Rodrigues, Bianca P ^a   Menezes, Thiago N ^a   Ceschim, Sara L ^b   Casarini, Dulce E ^c   Gava, Agata L ^d   Pereira, Thiago Melo C ^a,e   Vasquez, Elisardo C ^a,b   Campagnaro, Bianca P ^b   Meyrelles, Silvana S ^a  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^b UNIVERSIDADE VILA VELHA   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d MCMASTER UNIVERSITY   (Canada)

^e Federal Institute of Education   (Brazil)

Author keywords

Aging; Apoptosis; DNA damage; Hematopoietic stem cell; Oxidative stress; Senescence

Indexed keywords

REACTIVE OXYGEN METABOLITE;

AGING; ANIMAL; APOPTOSIS; BONE MARROW; CELL AGING; DNA DAMAGE; HEMATOPOIETIC STEM CELL; MALE; METABOLISM; MOUSE; PATHOLOGY;

AGING; ANIMALS; APOPTOSIS; BONE MARROW; CELL AGING; DNA DAMAGE; HEMATOPOIETIC STEM CELLS; MALE; MICE; REACTIVE OXYGEN SPECIES;

EID: 84944711692     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/s12929-015-0201-8     Document Type: Article

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