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Volumn 52, Issue 4, 2014, Pages 147-151

DNA damage response in adult stem cells

Author keywords

Cancer aging; DNA damage; Self renewal; Stem cells

Indexed keywords

PROTEIN P21; PROTEIN P53;

EID: 84895555081     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2013.12.005     Document Type: Review
Times cited : (27)

References (58)
  • 1
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: taking shape
    • Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 2006, 31:402-410.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 402-410
    • Shiloh, Y.1
  • 2
    • 45849099050 scopus 로고    scopus 로고
    • Living on a break: cellular senescence as a DNA-damage response
    • d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat. Rev. Cancer 2008, 8:512-522.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 512-522
    • d'Adda di Fagagna, F.1
  • 4
    • 34247251276 scopus 로고    scopus 로고
    • Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response
    • Zou L. Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response. Genes Dev. 2007, 21:879-885.
    • (2007) Genes Dev. , vol.21 , pp. 879-885
    • Zou, L.1
  • 6
    • 0037468232 scopus 로고    scopus 로고
    • MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
    • Lou Z., Minter-Dykhouse K., Wu X., Chen J. MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. Nature 2003, 421:957-961.
    • (2003) Nature , vol.421 , pp. 957-961
    • Lou, Z.1    Minter-Dykhouse, K.2    Wu, X.3    Chen, J.4
  • 9
    • 0036906303 scopus 로고    scopus 로고
    • Checkpoint signalling: focusing on 53BP1
    • Abraham R.T. Checkpoint signalling: focusing on 53BP1. Nat. Cell Biol. 2002, 4:E277-E279.
    • (2002) Nat. Cell Biol. , vol.4
    • Abraham, R.T.1
  • 12
    • 0037341599 scopus 로고    scopus 로고
    • Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
    • Lukas C., Falck J., Bartkova J., Bartek J., Lukas J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat. Cell Biol. 2003, 5:255-260.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 255-260
    • Lukas, C.1    Falck, J.2    Bartkova, J.3    Bartek, J.4    Lukas, J.5
  • 13
    • 22944462083 scopus 로고    scopus 로고
    • Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
    • Bekker-Jensen S., Lukas C., Melander F., Bartek J., Lukas J. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J. Cell Biol. 2005, 170:201-211.
    • (2005) J. Cell Biol. , vol.170 , pp. 201-211
    • Bekker-Jensen, S.1    Lukas, C.2    Melander, F.3    Bartek, J.4    Lukas, J.5
  • 14
    • 0035939844 scopus 로고    scopus 로고
    • Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53
    • Turenne G.A., Paul P., Laflair L., Price B.D. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53. Oncogene 2001, 20:5100-5110.
    • (2001) Oncogene , vol.20 , pp. 5100-5110
    • Turenne, G.A.1    Paul, P.2    Laflair, L.3    Price, B.D.4
  • 23
    • 77955322030 scopus 로고    scopus 로고
    • Stem cells and DNA damage: persist or perish?
    • Lane A.A., Scadden D.T. Stem cells and DNA damage: persist or perish?. Cell 2010, 142:360-362.
    • (2010) Cell , vol.142 , pp. 360-362
    • Lane, A.A.1    Scadden, D.T.2
  • 25
    • 33746617272 scopus 로고    scopus 로고
    • Hematopoietic stem cells: the paradigmatic tissue-specific stem cell
    • Bryder D., Rossi D.J., Weissman I.L. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am. J. Pathol. 2006, 169:338-346.
    • (2006) Am. J. Pathol. , vol.169 , pp. 338-346
    • Bryder, D.1    Rossi, D.J.2    Weissman, I.L.3
  • 26
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M., Hanada K., Hamada H., Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996, 273:242-245.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 27
    • 77956252530 scopus 로고    scopus 로고
    • Differential DNA damage response in stem and progenitor cells
    • Seita J., Rossi D.J., Weissman I.L. Differential DNA damage response in stem and progenitor cells. Cell Stem Cell 2010, 7:145-147.
    • (2010) Cell Stem Cell , vol.7 , pp. 145-147
    • Seita, J.1    Rossi, D.J.2    Weissman, I.L.3
  • 28
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki S., Iwama A., Takayanagi S., Morita Y., Eto K., Ema H., Nakauchi H. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 2006, 25:3515-3523.
    • (2006) EMBO J. , vol.25 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Morita, Y.4    Eto, K.5    Ema, H.6    Nakauchi, H.7
  • 38
    • 0037317521 scopus 로고    scopus 로고
    • The role of p53 in determining sensitivity to radiotherapy
    • Gudkov A.V., Komarova E.A. The role of p53 in determining sensitivity to radiotherapy. Nat. Rev. Cancer 2003, 3:117-129.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 117-129
    • Gudkov, A.V.1    Komarova, E.A.2
  • 39
    • 3543029166 scopus 로고    scopus 로고
    • Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and cell cycle arrest
    • Wilson J.W., Pritchard D.M., Hickman J.A., Potten C.S. Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and cell cycle arrest. Am. J. Pathol. 1998, 153:899-909.
    • (1998) Am. J. Pathol. , vol.153 , pp. 899-909
    • Wilson, J.W.1    Pritchard, D.M.2    Hickman, J.A.3    Potten, C.S.4
  • 40
    • 0031663614 scopus 로고    scopus 로고
    • The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine
    • Potten C.S., Grant H.K. The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine. Br. J. Cancer 1998, 78:993-1003.
    • (1998) Br. J. Cancer , vol.78 , pp. 993-1003
    • Potten, C.S.1    Grant, H.K.2
  • 41
    • 0034632668 scopus 로고    scopus 로고
    • Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine
    • Pritchard D.M., Print C., O'Reilly L., Adams J.M., Potten C.S., Hickman J.A. Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine. Oncogene 2000, 19:3955-3959.
    • (2000) Oncogene , vol.19 , pp. 3955-3959
    • Pritchard, D.M.1    Print, C.2    O'Reilly, L.3    Adams, J.M.4    Potten, C.S.5    Hickman, J.A.6
  • 42
    • 0030779865 scopus 로고    scopus 로고
    • P53 deficiency sensitizes clonogenic cells to irradiation in the large but not the small intestine
    • Hendry J.H., Cai W.B., Roberts S.A., Potten C.S. p53 deficiency sensitizes clonogenic cells to irradiation in the large but not the small intestine. Radiat. Res. 1997, 148:254-259.
    • (1997) Radiat. Res. , vol.148 , pp. 254-259
    • Hendry, J.H.1    Cai, W.B.2    Roberts, S.A.3    Potten, C.S.4
  • 43
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt A.J., Potten C.S., Kemp C.J., Hickman J.A., Balmain A., Lane D.P., Hall P.A. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 1994, 54:614-617.
    • (1994) Cancer Res. , vol.54 , pp. 614-617
    • Merritt, A.J.1    Potten, C.S.2    Kemp, C.J.3    Hickman, J.A.4    Balmain, A.5    Lane, D.P.6    Hall, P.A.7
  • 44
    • 0029048596 scopus 로고
    • Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia
    • Merritt A.J., Potten C.S., Watson A.J., Loh D.Y., Nakayama K., Hickman J.A. Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. J. Cell Sci. 1995, 108(Pt 6):2261-2271.
    • (1995) J. Cell Sci. , vol.108 , Issue.PART 6 , pp. 2261-2271
    • Merritt, A.J.1    Potten, C.S.2    Watson, A.J.3    Loh, D.Y.4    Nakayama, K.5    Hickman, J.A.6
  • 46
    • 1642580868 scopus 로고    scopus 로고
    • Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine
    • Potten C.S. Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine. Radiat. Res. 2004, 161:123-136.
    • (2004) Radiat. Res. , vol.161 , pp. 123-136
    • Potten, C.S.1
  • 48
    • 0035960043 scopus 로고    scopus 로고
    • The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
    • Vulliamy T., Marrone A., Goldman F., Dearlove A., Bessler M., Mason P.J., Dokal I. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 2001, 413:432-435.
    • (2001) Nature , vol.413 , pp. 432-435
    • Vulliamy, T.1    Marrone, A.2    Goldman, F.3    Dearlove, A.4    Bessler, M.5    Mason, P.J.6    Dokal, I.7
  • 49
    • 33646948760 scopus 로고    scopus 로고
    • Advances in understanding the genetic basis for bone-marrow failure
    • Lieberman L., Dror Y. Advances in understanding the genetic basis for bone-marrow failure. Curr. Opin. Pediatr. 2006, 18:15-21.
    • (2006) Curr. Opin. Pediatr. , vol.18 , pp. 15-21
    • Lieberman, L.1    Dror, Y.2
  • 52
    • 0041440074 scopus 로고    scopus 로고
    • Repopulating defect of mismatch repair-deficient hematopoietic stem cells
    • Reese J.S., Liu L., Gerson S.L. Repopulating defect of mismatch repair-deficient hematopoietic stem cells. Blood 2003, 102:1626-1633.
    • (2003) Blood , vol.102 , pp. 1626-1633
    • Reese, J.S.1    Liu, L.2    Gerson, S.L.3
  • 55
    • 29144450333 scopus 로고    scopus 로고
    • The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor
    • Morales M., Theunissen J.W., Kim C.F., Kitagawa R., Kastan M.B., Petrini J.H. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. Genes Dev. 2005, 19:3043-3054.
    • (2005) Genes Dev. , vol.19 , pp. 3043-3054
    • Morales, M.1    Theunissen, J.W.2    Kim, C.F.3    Kitagawa, R.4    Kastan, M.B.5    Petrini, J.H.6
  • 56
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.