Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 6455-6467

  Neacsu, Patricia ^a   Mazare, Anca ^b   Schmuki, Patrik ^b   Cimpean, Anisoara ^a  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Inflammatory mediators; Macrophage; Mitogen activated protein kinases; NF B; Titania nanotubes

Indexed keywords

BIOMATERIAL; I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOTUBE; NITRIC OXIDE; STRESS ACTIVATED PROTEIN KINASE; TITANIA NANOTUBE; TITANIUM; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; I KAPPA B; I KAPPA B KINASE ALPHA; LIPOPOLYSACCHARIDE; NFKBIA PROTEIN, MOUSE; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOMODULATION; INFLAMMATION; MACROPHAGE; MURINE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SURFACE PROPERTY; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; I-KAPPA B PROTEINS; INFLAMMATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NANOTUBES; NF-KAPPA B; NF-KAPPAB INHIBITOR ALPHA; NITRIC OXIDE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TITANIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84944190099     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S92019     Document Type: Article

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