Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 7, 2014, Pages 2373-2381

  Abarikwu, Sunny O ^a  

^a REDEEMER S UNIVERSITY   (Nigeria)

Author keywords

IL 6; Inflammation; Kolaviron; Lipopolysaccharide; MAPK; RAW macrophage

Indexed keywords

BETA1 1 INTERFERON; BETA1 INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 6; KOLAVIRON; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C JUN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYMATIC DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GARCINIA KOLA; GENE EXPRESSION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

IL-6; INFLAMMATION; KOLAVIRON; LIPOPOLYSACCHARIDE; MAPK; RAW MACROPHAGE;

ANIMALS; FLAVONOIDS; GARCINIA KOLA; GENE EXPRESSION REGULATION; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; SEEDS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84900410961     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.03.006     Document Type: Article

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