CytoAnti-inflammatory effects of saponins derived from the roots of Platycodon grandiflorus in lipopolysaccharide-stimulated BV2 microglial cells

International Journal of Molecular Medicine

Volumn 31, Issue 6, 2013, Pages 1357-1366

  Jang, Kyung Jun ^a   Ki Kim, Hong ^a   Han, Min Ho ^b   Oh, You Na ^c   Yoon, Hyun Min ^a   Chung, Yoon Ho ^c   Kim, Gi Young ^d   Hwang, Hye Jin ^b,e   Kim, Byung Woo ^b   Choi, Yung Hyun ^a,b  

^a Dong Eui University   (South Korea)

^b Dong Eui University   (South Korea)

^c Duksan BandF Co Ltd   (South Korea)

^d Jeju National University   (South Korea)

^e Department of Food and Nutrition   (South Korea)

Author keywords

AKT; Anti inflammation; Mitogen activated protein kinases; Nuclear factor B; Platycodon grandiflorus; Saponins

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN KINASE B; SAPONIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; AUTACOID; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CYTOKINE PRODUCTION; ENZYME ACTIVATION; MICROGLIA; NONHUMAN; PLANT ROOT; PLATYCODON; PLATYCODON GRANDIFLORUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE; PROTEIN TRANSPORT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT ROOTS; PLATYCODON; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; SAPONINS;

EID: 84876380267     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1330     Document Type: Article

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