Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated RAW 264.7 cells via p38 kinase and nuclear factor-κB signaling pathways

European Journal of Pharmacology

Volumn 601, Issue 1-3, 2008, Pages 171-178

  Choi, Hwa Jung ^a   Eun, Jae Soon ^b   Park, Young Ran ^a   Kim, Dae Keun ^b   Li, Rihua ^b   Moon, Woo Sung ^a   Park, Jeong Mi ^a   Kim, Hyung Sup ^a   Cho, Nam Pyo ^c   Cho, Sung Dae ^c   Soh, Yunjo ^a  

^a Chonbuk National University   (South Korea)

^b Woosuk University   (South Korea)

^c Department of Oral Anatomy   (South Korea)

Author keywords

Epimedium koreanum; Ikarisoside A; Inflammation; iNOS; LPS; Macrophage; NF B; NO; p38; RAW 264.7

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; EPIMEDIUM EXTRACT; IKARISOSIDE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; EPIMEDIUM KOREANUM; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BONE MARROW; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIMEDIUM; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOSIDES; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 56949083956     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.09.032     Document Type: Article

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