Anti-inflammatory effect of sargachromanol G isolated from Sargassum siliquastrum in RAW 264.7 cells

Archives of Pharmacal Research

Volumn 35, Issue 8, 2012, Pages 1421-1430

  Yoon, Weon Jong ^a,c   Heo, Soo Jin ^b   Han, Sang Chul ^a   Lee, Hye Ja ^a   Kang, Gyeoung Jin ^a   Kang, Hee Kyoung ^a   Hyun, Jin Won ^a   Koh, Young Sang ^a   Yoo, Eun Sook ^a  

^a Jeju National University School of Medicine   (South Korea)

^b Korea Research Institute of Ships and Ocean Engineering   (South Korea)

^c Jeju Biodiversity Research Institute   (South Korea)

Author keywords

Inflammatory markers; MAPK; NF B; Pro inflammatory cytokines; Sargachromanol G; Sargassum siliquastrum

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN P50; SARGACHROMANOL G; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; MACROPHAGE; MOUSE; NONHUMAN; SARGASSUM; SARGASSUM SILIQUASTRUM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZOPYRANS; CELL LINE; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORYLATION; SARGASSUM;

EID: 84868088099     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-012-0812-5     Document Type: Article

References (27)

1. Ahmad, N., Chen, L. C., Gordon, M. A., Laskin, J. D., and Laskin, D. L., Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia. J. Leukoc. Biol., 71, 1005-1011 (2002).
2. Brown, M. D. and Sacks, D. B., Compartmentalised MAPK pathways. Handb. Exp. Pharmacol., 186, 205-235 (2008).
3. Ding, C., Cicuttini, F., Li, J., and Jones, G., Targeting IL-6 in the treatment of inflammatory and autoimmune diseases. Expert Opin. Investig. Drugs, 18, 1457-1466 (2009).
4. Edwards, M. R., Bartlett, N. W., Clarke, D., Birrell, M., Belvisi, M., and Johnston, S. L., Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. Pharmacol. Ther., 121, 1-13 (2009).
5. Feldmann, M., Brennan, F. M., Chantry, D., Haworth, C., Turner, M., Katsikis, P., Londei, M., Abney, E., Buchan, G., Barrett, K., Corcoran, A., Kissonerghis, M., Zheng, R., Grubeck-Loebenstein, B., Barkley, D., Chu, C. Q., Field, M., and Maini, R. N., Cytokine assays: role in evaluation of the pathogenesis of autoimmunity. Immunol. Rev., 119, 105-123 (1991).
6. Feldmann, M., Many cytokines are very useful therapeutic targets in disease. J. Clin. Invest., 118, 3533-3536 (2008).
7. Fernandez, M., Rios, J. C., Jos, A., and Repetto, G., Comparative cytotoxicity of alachlor on RTG-2 trout and SH-SY5Y human cells. Arch. Environ. Contam. Toxicol., 51, 515-520 (2006). (Pubitemid 44581814)
8. Fogal, B. and Hewett, S. J., Interleukin-1beta: a bridge between inflammation and excitotoxicity? J. Neurochem., 106, 1-23 (2008).
9. Fujihara, M., Muroi, M., Tanamoto, K., Suzuki, T., Azuma, H., and Ikeda, H., Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex. Pharmacol. Ther., 100, 171-194 (2003). (Pubitemid 37377912)
10. Ghosh, S. and Hayden, M. S., New regulators of NF-kappaB in inflammation. Nat. Rev. Immunol., 8, 837-848 (2008).
11. Guha, M. and Mackman, N., LPS induction of gene expression in human monocytes. Cell Signal., 13, 85-94 (2001). (Pubitemid 32222977)
12. Heo, S. J., Yoon, W. J., Kim, K. N., Ahn, G. N., Kang, S. M., Kang, D. H., Affan, A., Oh, C., Jung, W. K., and Jeon, Y. J., Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food Chem. Toxicol., 48, 2045-2051 (2010).
13. Ji, R. R., Gereau, R. W., 4th., Malcangio, M., and Strichartz, G. R., MAP kinase and pain. Brain Res. Rev., 60, 135-148 (2009).
14. Kim, E. Y. and Moudgil, K. D., Regulation of autoimmune inflammation by pro-inflammatory cytokines. Immunol. Lett., 120, 1-5 (2008).
15. Kim, J. H., Bachmann, R. A., and Chen, J., Interleukin-6 and insulin resistance. Vitam. Horm., 80, 613-633 (2009).
16. Kofler, S., Nickel, T., and Weis, M., Role of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation. Clin. Sci., 108, 205-213 (2005). (Pubitemid 40343567)
17. Lapa e Silva, J. R., Possebon da Silva, M. D., Lefort, J., and Vargaftig, B. B., Endotoxin, asthma, and allergic immune responses. Toxicology, 152, 31-35 (2000).
18. Lee, H. J., Hyun, E. A., Yoon, W. J., Kim, B. H., Rhee, M. H., Kang, H. K., Cho, J. Y, and Yoo, E. S., In vitro antiinflammatory and anti-oxidative effects of Cinnamomum camphora extracts. J. Ethnopharmacol., 103, 208-216 (2006). (Pubitemid 41796919)
19. Malemud, C. J. and Miller, A, H., Pro-inflammatory cytokineinduced SAPK/MAPK and JAK/STAT in rheumatoid arthritis and the new anti-depression drugs. Expert Opin. Ther. Targets, 12, 171-183 (2008). (Pubitemid 351284960)
20. Mehra, V. C., Ramgolam, V. S., and Bender, J. R., Cytokines and cardiovascular disease. J. Leukoc. Biol., 78, 805-818 (2005). (Pubitemid 41384397)
21. Murakami, A. and Ohigashi, H., Targeting NOX, iNOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals. Int. J. Cancer, 121, 2357-2363 (2007). (Pubitemid 350022403)
22. Ren, K. and Torres, R., Role of interleukin-1beta during pain and inflammation. Brain Res. Rev., 60, 57-64 (2009).
23. Sugita, T., Targeting therapy for inflammatory diseases by anti-TNF-alpha biologics. Yakugaku Zasshi, 129, 19-24 (2009).
24. Sweet, M. J. and Hume, D. A., Endotoxin signal transduction in macrophages. J. Leukoc. Biol., 60, 8-26 (1996). (Pubitemid 26248877)
25. Walsh, N. C., Crotti, T. N., Goldring, S. R., and Gravallese, E. M., Rheumatic diseases: the effects of inflammation on bone. Immunol. Rev., 208, 228-251 (2005). (Pubitemid 41746396)
26. Wong, E. T. and Tergaonkar, V., Roles of NF-kappaB in health and disease: mechanisms and therapeutic potential. Clin. Sci., 116, 451-465 (2009).
27. Yoon, W. J., Moon, J. Y., Song, G., Lee, Y. K., Han, M. S., Lee, J. S., Ihm, B. S., Lee, W. J., Lee, N. H., and Hyun, C. G., Artemisia fukudo essential oil attenuates LPS-induced inflammation by suppressing NF-kappaB and MAPK activation in RAW 264.7 macrophages. Food Chem. Toxicol., 48, 1222-1229 (2010).