Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation

Cell Cycle

Volumn 14, Issue 16, 2015, Pages 2667-2676

  Fazolini, Narayana PB ^a   Cruz, André LS ^b   Werneck, Miriam BF ^b   Viol, João PB ^a   Maya Monteiro, Clarissa M ^a   Bozza, Patrícia T ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Leptin; Lipid droplets; mTOR; Rapamycin

Indexed keywords

CXCL1 CHEMOKINE; CYCLOOXYGENASE 2; FAT DROPLET; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; CYTOKINE; MTOR PROTEIN, RAT; PTGS2 PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; INTESTINE EPITHELIUM CELL; INTRACELLULAR SIGNALING; LIPID METABOLISM; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BIOSYNTHESIS; CELL CYCLE; CELL LINE; CYTOLOGY; ENZYME INDUCTION; EPITHELIUM CELL; GENETICS; INTESTINE MUCOSA; METABOLISM; OBESITY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOKINES; ENZYME INDUCTION; EPITHELIAL CELLS; INTESTINAL MUCOSA; LEPTIN; LIPID DROPLETS; LIPID METABOLISM; OBESITY; RATS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84943809084     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1041684     Document Type: Article

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