FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16274-16281

  Qi, Wentao ^a,d   Fitchev, Philip S ^b   Cornwell, Mona L ^b   Greenberg, Jordan ^a   Cabe, Maleen ^a   Weber, Christopher R ^c   Roy, Hemant K ^a   Crawford, Susan E ^b   Savkovic, Suzana D ^a  

^a NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d ACADEMY OF STATE ADMINISTRATION OF GRAIN   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROLIFERATIVE EFFECT; COLON CANCER CELLS; EPITHELIAL PROLIFERATION; FEEDBACK REGULATION; FORKHEAD TRANSCRIPTIONS; HUMAN COLON CANCER CELLS; NEGATIVE REGULATORS; THERAPEUTIC INTERVENTION;

CYTOLOGY; DROPS; MAMMALS; TRANSCRIPTION FACTORS; TUMORS;

CELLS;

COAT PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FAT DROPLET; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN PLIN2; SIRTUIN 6; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL GROWTH; CELL PROLIFERATION; COLON CANCER; COLONIC EPITHELIAL CELL; CONTROLLED STUDY; FEEDBACK SYSTEM; GROWTH INHIBITION; HUMAN; HUMAN CELL; INTESTINE CELL; LIPID METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

CANCER BIOLOGY; COLON CANCER; COLORECTAL CANCER; FOXO3; GROWTH; GROWTH FACTORS; LIPID DROPLET; LIPIDS; TUMOR METABOLISM; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; COLON; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EPITHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTESTINAL MUCOSA; LIPID METABOLISM; MEMBRANE PROTEINS; MICE; NEOPLASM PROTEINS; PROMOTER REGIONS, GENETIC; SIRTUINS;

MUS;

EID: 84878762399     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.470617     Document Type: Article

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