Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice

Carcinogenesis

Volumn 35, Issue 9, 2014, Pages 2134-2141

  Higurashi, Takuma ^a   Endo, Hiroki ^a   Uchiyama, Takashi ^a   Uchiyama, Shiori ^a   Yamada, Eiji ^a   Ohkubo, Hidenori ^a   Sakai, Eiji ^a   Takahashi, Hirokazu ^a   Maeda, Shin ^a   Wada, Koichiro ^b   Natsumeda, Yutaka ^a   Hippo, Yoshitaka ^c   Nakajima, Atsushi ^a   Nakagama, Hitoshi ^c  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR; LEPTIN RECEPTOR B; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ABERRANT CRYPT FOCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; COLON CARCINOGENESIS; COLON MUCOSA; COLON TUMOR; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE INACTIVATION; INTESTINE EPITHELIUM; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SYSTEMIC DISEASE; TRANSCRIPTION INITIATION; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; COLON; COLONIC NEOPLASMS; DIET, HIGH-FAT; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HUMANS; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84906832450     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu135     Document Type: Article

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