Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway

Journal of Biosciences

Volumn 37, Issue 1, 2012, Pages 91-101

  Wang, Di ^a,b   Chen, Jian ^b   Chen, Hui ^b   Duan, Zhi ^b   Xu, Qimei ^b   Wei, Meiyan ^b   Wang, Lianghua ^b   Zhong, Meizuo ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b First Hospital of Changsha   (China)

Author keywords

Colorectal carcinoma; HCT 116; leptin; mammalian target of rapamycin (mTOR); phosphatidylinositol 3 kinase PI3K

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE;

APOPTOSIS; CANCER; ENZYME ACTIVITY; EPIDEMIOLOGY; HORMONE; OBESITY;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL; CANCER STAGING; CELL DIFFERENTIATION; CELL PROLIFERATION; CHINESE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; REGULATORY MECHANISM;

APOPTOSIS; ASIAN CONTINENTAL ANCESTRY GROUP; CELL PROLIFERATION; CHROMONES; COLORECTAL NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; LEPTIN; MORPHOLINES; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 84859746151     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-011-9172-4     Document Type: Article

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