MiR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

EMBO Reports

Volumn 16, Issue 10, 2015, Pages 1358-1377

  Fierro Fernández, Marta ^a   Busnadiego, Óscar ^a   Sandoval, Pilar ^a   Espinosa Díez, Cristina ^a   Blanco Ruiz, Eva ^a   Rodríguez, MacArena ^b   Pian, Héctor ^b   Ramos, Ricardo ^c   López Cabrera, Manuel ^a   García Bermejo, Maria Laura ^b   Lamas, Santiago ^a  

^a CSIC   (Spain)

^b HOSPITAL RAMÓN Y CAJAL   (Spain)

^c Parque Científico de Madrid   (Spain)

Author keywords

fibrosis; miRNAs; myofibroblast; oxidative stress; TGF signaling

Indexed keywords

BLEOMYCIN; MICRORNA; MICRORNA 9; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; NOX4 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ARTICLE; CONTROLLED STUDY; FIBROBLAST; FIBROGENESIS; FIBROSING ALVEOLITIS; FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG FIBROBLAST; MESOTHELIUM CELL; MYOFIBROBLAST; PERITONEAL DIALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; LUNG FIBROSIS; METABOLISM; MOUSE; OXIDATIVE STRESS; PHYSIOLOGY;

ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; FIBROBLASTS; FIBROSIS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MICE; MICRORNAS; MYOFIBROBLASTS; NADPH OXIDASE; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84942819422     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540750     Document Type: Article

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